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Topic: Chromosome 17 (human)

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	Fcr - Fc receptor
		IgG Fc receptor II (Fc gamma RII) on human monocytes is polymorphic with respect to its appearance on gels after isoelectric focusing and with respect to its ability to mediate T lymphocyte proliferation induced by murine anti-CD3 mAb of the IgG1 isotype (i.e., its ability to bind murine IgG1).
		Both forms of recombinant human D-factor were active on the murine myeloid leukemia cell line M1 in a dose- and time-dependent manner for the inhibition of [3H]thymidine incorporation, and also induced phagocytosis, Fc receptor expression, and prostaglandin E2 synthesis by M1 cells.
		Human resting B lymphocytes entered a state of sustained proliferation when incubated with both the mouse fibroblastic Ltk- cell line that had been transfected with the human Fc receptor (Fc gamma RII/CDw32) and monoclonal antibodies to CD40.
	www.pdg.cnb.uam.es /UniPub/iHOP/gg/147120.html (5839 words)

	BRCA1 Gene - July 2001: 707715 (Site not responding. Last check: 2007-10-20)
		Interestingly, although chromosome aberrations were evident, aneuploidy was not observed.
		Human granulosa cells obtained during in vitro fertilization procedures were cultured with 10, 10(2), 10(3), or 10(4) ng/mL insulin with or without preincubation with 100 nM wortmannin, a specific irreversible inhibitor of PI-3 kinase.
		Additional studies were carried out in cultures of human ovarian cells prepared from homogenized whole ovarian tissue of a woman with a family history of breast cancer and a mutation of BRCA-1 gene who underwent bilateral oophorectomy.
	www.acor.org /cnet/707715.html (4604 words)

	Chromosome 17 - Genetics Home Reference
		Chromosome 17 is one of the 23 pairs of chromosomes in humans.
		Chromosome 17 spans more than 81 million base pairs (the building material of DNA) and represents between 2.5 and 3 percent of the total DNA in cells.
		Genes on chromosome 17 are among the estimated 20,000 to 25,000 total genes in the human genome.
	ghr.nlm.nih.gov /chromosome=17 (390 words)

	chromosome 7 (Site not responding. Last check: 2007-10-20)
		Human DPPX cDNA clones were isolated from a hippocampus cDNA library using a fragment of a previously isolated bovine DPPX clone as a probe (Yokotani et al., 1993 (212757)).
		Human PMS2 is one of the 4 bacterial DNA mismatch repair gene homologs found to be mutated in the germline of hereditary nonpolyposis colon cancer (HNPCC) patients.
		The gene was localized to chromosome 7 by PCR analysis of a marker fragment with somatic cell hybrids (Papadopoulos et al., 1994 (320862)) and further mapped to 7p22 by FISH with a genomic Pl clone containing the 3'region of the gene (Nicolaides et al., 1994 (386274)).
	www.genet.sickkids.on.ca /SCW7-2.html (6956 words)

	1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and ....
		Chromosome preparations from patient 2 were made from a bone marrow aspirate that was extensively infiltrated with neuroblastoma cells.
		Co-hybridization of MYCN (pNb-9), a chromosome 17 library (pBS-17), and a chromosome 17 centr omere probe (p17H8) showed that the two HSRs in N206 were the result of MYCN amplification and that they were integrated in the long arms of chromosomes 17 (Fig.4k).
		When comparing the size of the translocated chromosome 17 segment with the normal chromosomes 17 in the 1;17, 11;1 7, and other chromosome 17 rearrangements, it appears that nearly the entire 17q arm is always translocated, provided no chromosome 17 material was duplicated (Fig.4).
	allserv.rug.ac.be /~fspelema/neubla/researc/trans.htm (5742 words)

	Trisomy 17 mosaicism (Site not responding. Last check: 2007-10-20)
		Trisomy 17 mosaicism has been occasionally detected on chorionic villus sampling or amniocentesis and is usually associated with a normal outcome with no evidence of the trisomy 17 cells in newborn blood.
		One case of confined placental mosaicism for trisomy 17 was reported in a large study of chromosomal mosaicism detected on CVS.
		Although peripheral blood lymphocyte chromosomes were normal, trisomy 17 was present in the skin fibroblasts.
	www.medgen.ubc.ca /wrobinson/mosaic/trisomy17.htm (441 words)

	Multiple Sclerosis References 2003; Authors: M
		The most abundant secretory mediator of the human mast cell is the tetrameric protease tryptase.
		Prolactin maps on chromosome 6p, about 11-kb telomeric to HLA-DRB1 and PRLR in 5p12-13, which revealed evidence of linkage with MS in different populations.
		Based on the presence of consanguinity, the a priori hypothesis was that the disease is transmitted in an autosomal recessive fashion in the pedigree.
	lansbury.bwh.harvard.edu /ms_references_2003_authors_m.htm (9387 words)

	Human Genetics
		Remember that a translocation occurs when one chromosome (or a fragment) is transferred to a non-homologous chromosome.
		A Gene Map of the Human Genome As of mid 1996.
		Human Karyotypes Exhibiting Various Abnormalities (from Bioweb) Drawings of a number of human karyotypes.
	www.emc.maricopa.edu /faculty/farabee/BIOBK/BioBookhumgen.html (1948 words)

	Diabetes: Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13 (Site not responding. Last check: 2007-10-20)
		The regional localization was determined by hybridization of the probe to cell hybrids having translocations of human chromosome 17 and by in situ hybridization of [.sup.3H]-labeled phJHT-3 to normal human prometaphase lymphocyte chromosomes [7].
		The chromosomal assignment of GLUT4 was determined by correlating the presence of this gene with that of a specific human chromosome in a panel of human-mouse somatic cell hybrids having different numbers and combinations of human chromosomes.
		The chromosomal localization of genes encoding four human facilitative transporters have been determined (7,15, 16; herein), and all are on different chromosomes (Table 3).
	www.findarticles.com /p/articles/mi_m0922/is_n8_v38/ai_13384278 (1331 words)

	IQ Intelligence Tests Books 1970-1989 (Site not responding. Last check: 2007-10-20)
		Early malnutrition and mental development : proceedings of a symposium jointly sponsored by the National institute of child health and human development, Bethesda, Maryland, the Swedish international development authority, the Swedish nutrition foundation, and the World health organization : including papers from an ensuing WHO workshop.
		Human intelligence : perspectives on its theory and measurement.
		Stott, D. Issues in the intelligence debate : a juxtaposition of the arguments and an appraisal by Denis H. Stott of Intelligence, the battle for the mind, by H.J. Eysenck and L.J. Kamin.
	www.medlina.com /iq_intelligence_tests_books_1970-1989.htm (3773 words)

	ESHG Posters 11
		Human chromosome 22 is one of the smallest autosomes involved in many human genetic disease.
		Human BAC clones from 17p13 and 17q21.3 were identified, which span the inversion breakpoints.
		Chromosome 21 (HC21) is the smallest human chromosome.
	www.medacad.org /eshg/abstracts/posters11.htm (4190 words)

	Conserved Synteny in Rat and Mouse for a Blood Pressure QTL on Human Chromosome 17 -- Zimdahl et al. 39 (6): 1050 -- ...
		on human chromosome 17 and rat chromosome 10 are syntenic.
		Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10.
		Human hypertension caused by mutations in WNK kinases.
	hyper.ahajournals.org /cgi/content/full/39/6/1050 (1315 words)

	Human Genetics - UPD Maternal Chromosome 17 (Site not responding. Last check: 2007-10-20)
		The paternal chromosome is shown on the right.
		Ledbetter, D.H. and Engel, E. (1995): Uniparental disomy in humans: development of an imprinting map and its implications for prenatal diagnosis.
		Morison, I.M. and Reeve, A.E.(1998): A catalogue of imprinted genes and parent-of-origin effects in humans and animals.
	www.genes.uchicago.edu /upd/upd17m.html (57 words)

	Chromosome 17 (Site not responding. Last check: 2007-10-20)
		and delta subunit genes to chromosome 2 and the beta subunit gene ro chromosome 17.
		12.630.995 2.83 335 24 117 81 17 9 10.692 1.177 1.94 335 1120 118...
		Chromosome 17 in which both ends have been lost (deletion) and the broken ends have reunited to form a ring...
	www.e-dna-tests.info /resources/chromosome-17.html (443 words)

	DHEA, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, hair loss, hair growth, buy Rx ... (Site not responding. Last check: 2007-10-20)
		The study was aimed at clarifying the relative roles of genetic and environmental factors in determination of the blood concentration of high density lipoprotein cholesterol (HDL-C) in the Russian population.
		The comparison of transgenic mice overexpressing human or murine apolipoprotein A-II has highlighted major structural differences between the two proteins; they have opposite effects on HDL size, apolipoprotein A-I content, plasma concentration, and protection from oxidation.
		Human apolipoprotein A-II is more hydrophobic, displaces apolipoprotein A-I from HDL, accelerates apolipoprotein A-I catabolism, and its plasma concentration is decreased by fasting.
	www.twinpharm.com /ref-lipoprotein/lipoprotein-research-abs4.50.html (1212 words)

	Comparative Analysis of the {alpha}-Like Globin Clusters in Mouse, Rat, and Human Chromosomes Indicates a Mechanism ...
		Dot plots of the mouse Chromosome 17 sequence against the human Chromosome 16 (A) and mouse Chromosome 11 (B) sequences.
		ancestral mouse Chromosome 17 and it is proposed that a recombination
		The IL-9 receptor gene (IL9R): Genomic structure, chromosomal localization in the pseudoautosomal region of the long arm of the sex chromosomes, and identification of IL9R pseudogenes at 9qter, 10pter, 16pter, and 18pter.
	www.genome.org /cgi/content/full/14/4/623 (3616 words)

	Exploring Genes & Genetic Disorders
		cientists, enabled by the Human Genome Project, are churning out an unprecedented volume of data on human chromosomes and the tens of thousands of genes residing on them, many associated with genetic disorders.
		Each of the 24 different human chromosomes featured on this poster can be viewed online.
		Learn about the physical makeup of human chromosomes and see some of the genes that have been found on each one.
	www.ornl.gov /sci/techresources/Human_Genome/posters/chromosome (556 words)

	Human T cell leukemia viruses use a receptor determined by human chromosome 17.
		Human T cell leukemia viruses use a receptor determined by human chromosome 17.
		Human-mouse somatic cell hybrids were used to determine which human chromosome was required to confer susceptibility to VSV(HTLV) infection.
		The only human chromosome common to all susceptible cell hybrids was chromosome 17, and the receptor gene was localized to 17cen-qter.
	www.aegis.com /aidsline/1989/mar/M8930313.html (372 words)

	Human Chromosome Launchpad
		This site is provided as a single-source launchpad to information about each human chromosome.
		Choose databases and other information resources by "pointing and clicking" on one of the pictured chromosomes or by using the list of links below.
		Each chromosome page provides links to gene maps, sequences, associated genetic disorders, nonhuman genetic models, identified genes, research efforts and laboratories, and other information as available.
	www.ornl.gov /sci/techresources/Human_Genome/launchpad (159 words)

	Zebrafish Comparative Genomics and the Origins of Vertebrate Chromosomes -- Postlethwait et al. 10 (12): 1890 -- Genome ...
		chromosomes with orthologs on Hsa17, one with the precursors to
		The overlapping conserved syntenies of orthologs of these human chromosome segments in fish, mouse, cat, and human suggest that they were originally part of a single chromosome that fragmented in the tetrapod lineage.
		Hansmann, I. Structural variability of human chromosome 9 in relateion to its evolution.
	www.genome.org /cgi/content/full/10/12/1890 (7524 words)

	Publikationen 1997
		Remission was achieved in 17 (36%) and marker-negative remission in eight (17%).
		These data demonstrate that under certain experimental conditions efficient YAC transfer into human cells by spheroplast fusion is possible and may be useful for the cloning of human disease-related genes.
		In contrast, doxorubicin-resistant human ovarian A2780/Dx5 tumor cells [pgp170 phenotype] were 6.2-fold resistant to NB-506, whereas resistance to CPT was 2.6-fold.
	www.uni-essen.de /tumorforschung/1997.html (9718 words)

	10 Chromosome (Site not responding. Last check: 2007-10-20)
		Chromosome 10, Monosomy 10p is a rare chromosomal disorder in which the end (distal) portion of the short arm (p) of chromosome 10 is missing (deleted or monosomic).
		Excluding the pseudogenes, human chromosome 10 is a chromosome with an average gene density (10.4 genes...
		of heterozygosity for loci on chromosome 10 is associated with morphologically malignant...
	www.e-dna-tests.info /resources/10-chromosome.html (632 words)

	HUMAN CHROMOSOME #17 (Site not responding. Last check: 2007-10-20)
		Regional mapping of genes encoding human steroidogenic enzymes: P450scc to 15q23-q24, adrenoxin to 11q22; adrenoxin reductase to 17q24-25; and P450c17 to 10q24-q25.
		Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7.
		Human somatostatin receptor genes: Localization of SSTR5 to human chromosomes 14, 17, and 22, and identification of simple tandem repeat polymorphisms.
	www.il-st-acad-sci.org /genecats/hsa17.html (1174 words)

	POR - Content (Site not responding. Last check: 2007-10-20)
		Genetic alterations of chromosome 17 have been reported to occur frequently both in human sporadic and familial malignancies.
		The present study was undertaken to explore the possible involvement of chromosome 17 genes including TP53 and the breast cancer susceptibility BRCA1 tumor suppressor genes in the development of sporadic osteogenic sarcoma.
		In 53% of the cases studied at least one locus on chromosome 17 was affected by LOH.
	www.webio.hu /por/content.php?article=511 (294 words)

	DHEA, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, hair loss, hair growth, buy Rx ... (Site not responding. Last check: 2007-10-20)
		In human plasma, PAF acetylhydrolase (EC 3.1.1.47) circulates in a complex with low density lipoproteins (LDL) and high density lipoproteins (HDL).
		Two domains within the primary sequence of human PAF acetylhydrolase, tyrosine 205 and residues 115 and 116, were important for its binding to LDL.
		When residues 115 and 116 from human PAF acetylhydrolase were introduced into mouse PAF acetylhydrolase (which normally does not associate with LDL), the mutant mouse PAF acetylhydrolase associated with lipoproteins.
	www.twinpharm.com /ref-catabolism/catabolism-research-abs4.49.html (1347 words)

	Keyword (Site not responding. Last check: 2007-10-20)
		The finding implies that humans' social interactions are pre-programmed to some extent and that external influences - "nurture" in contrast to "nature" - may be less important.
		Dozens of new genes identified: By intensely and systematically comparing the human X chromosome to genetic information from chimpanzees, rats and mice, a team of scientists from the United States and India has uncovered dozens of new genes, many of which are located in regions of the chromosome already tied to disease.
		Regions of the X chromosome, one of the two sex chromosomes (Y is the other), have been linked to mental retardation and numerous other disorders, but finding the particular genetic abnormalities involved has been difficult.
	www.freerepublic.com /focus/keyword?k=genetics (5419 words)

	Evidence for Linkage Between Essential Hypertension and a Putative Locus on Human Chromosome 17 -- Baima et al. 34 (1): ...
		Human chromosome 17 is syntenic with rat chromosome 10, and evidence
		the chromosome 17 blood pressure QTL were tested (Figure).
		Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 20.
	hyper.ahajournals.org /cgi/content/full/34/1/4 (2814 words)

	Human to Mouse Homology Region Map, Chromosome 17
		Gene order has been changed from that shown in the chromosome committee reports or online databases, as required by high-resolution human physical mapping data; these data also indicate a probable difference between human and mouse organization, e.g.
		Subsequent hyperlinks on the marker will provide marker details and hyperlink to the actual Human Gene Map region (by selecting the interval defined by the Genethon Map loci intervals).
		The asterisk character ('') is used to indicate a different region of homology on the same mouse chromosome*.
	www.ncbi.nlm.nih.gov /Omim/Homology/human17.html (298 words)

	The human X chromosome (Site not responding. Last check: 2007-10-20)
		The detailed sequence of the human X chromosome is published this week, together with a survey of inactivated X genes in females.
		The X inactivation profile has important clinical implications, as the unique nature of sex chromosomes means that it contains a disproportionate number of disease-causing genes.
		With both the X and Y chromosomes sequenced, their evolution from a pair of 'normal' chromosomes can be studied in detail.
	www.nature.com /nature/links/050317/050317-1.html (150 words)

	HUMAN GENOME PROJECTS
		Chr3, Human chromosome 3 database (University of Texas)
		Chr21 at Tokyo Univ., Human chromosome 21 Sequence Map (University of Tokyo)
		Chr21 at ERI, Human chromosome 21 genomic sequence database (Eleanor Roosevelt Institute)
	www.dbbm.fiocruz.br /TcruziDB/human.htm (60 words)

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