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	Chronic Granulomatous Disease CGD
		Chronic Granulomatous Disease Thirty years ago when chronic granulomatous disease was first recognized, most of the children who had inherited the illness died before they reached their tenth birthday.
		Chronic Granulomatous Disease (CGD) is a genetically determined (inherited) disease characterized by an inability of the patient's phagocytic cells (polymorphonuclear leukocytes and monocytes) to kill certain microorganisms.
		chronic granulomatous disease CGD An inherited abnormality of certain cells of the immune system that "ingest" bacteria and kill them ; the abnormality results in infection by certain types of bacteria.
	www.doctorpage.com /findit/Diseases_and_Conditions/Chronic_Granulomatous_Disease_CGD/index.htm (109 words)

	Granulomatous Disease (Site not responding. Last check: 2007-11-06)
		Chronic granulomatous disease(CGD) is a rare inherited immunodeficiency disorder characterized by recurrent, often life-threatening bacterial and fungal infections, as well as granulomas in multiple organs.
		In chronic granulomatous disease, there is a defect in the NADPH oxidase apparatus rendering neutrophils defective in their ability to kill certain types of bacteria and fungi.
		In summary, CGD is a rare inherited immunodeficiency disorder involving a defect in the neutrophils response to infection.
	cats.med.uvm.edu /cats_teachingmod/radiology/radiology_html/teaching/radio_adult/granulomatous%20_disease/granulo.htm (937 words)

	Chronic granulomatous disease - Wikipedia, the free encyclopedia
		In medicine (genetics and pediatrics) chronic granulomatous disease (CGD) is a hereditary disease where neutrophil granulocytes are unable to destroy ingested pathogens.
		Four genes have been implicated in CGD (p is the weight of the protein in kDa; the g means glycoprotein):
		This has been reported in women who are homozygous for the genetic defect causing glucose-6-phosphate dehydrogenase deficiency (G6PD), which is characterised by reduced NADPH levels.
	en.wikipedia.org /wiki/Chronic_granulomatous_disease (224 words)

	chronic granulomatous disease -- Encyclopædia Britannica
		Chronic hepatitis is the result of unresolved acute injury and is associated with ongoing liver damage.
		The formal name for the disease is erythema infectiosum, which means “infectious redness.” The name fifth disease was applied to the condition because it was the fifth pink-red infectious rash of childhood to be described.
		Heartworm disease is caused by the parasitic filarial worm Dirofiliaria immitis, the adults of which colonize the right ventricle of the heart and the pulmonary artery.
	www.britannica.com /eb/article-9082459 (717 words)

	Chronic Granulomatous Disease \| Principal Health News
		Chronic granulomatous disease (CGD) is an inherited disorder in which white blood cells lose their ability to destroy certain bacteria and fungi.
		CGD is an X-linked genetic disease, meaning the defective gene is carried on the X chromosome (one of the sex chromosomes).
		In CGD there is a defect in the ability of the white blood cells to kill bacteria and fungi.
	www.principalhealthnews.com /topic/topic100586620 (627 words)

	Chronic granulomatous disease
		Chronic granulomatous disease is an inherited abnormality of certain cells of the immune system that normally kill bacteria (phagocytic cells).
		Chronic granulomatous disease (CGD) is transmitted 50-60% of the time as a recessive sex-linked trait.
		Chronic swelling of the lymph nodes in the neck with abscess formation is common.
	www.healthcentral.com /ency/408/001239.html (443 words)

	eMedicine - Chronic Granulomatous Disease : Article by Roman Nowicki, MD, PhD
		CGD is a syndrome that typically manifests as pneumonia, infectious dermatitis, and recurrent or severe subcutaneous abscess formation.
		Patients with CGD are susceptible to severe and recurrent infections due to catalase-positive organisms and organisms resistant to nonoxidative killing.
		Chowdhury MM, Anstey A, Matthews CN: The dermatosis of chronic granulomatous disease.
	www.emedicine.com /derm/topic719.htm (3365 words)

	ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Chronic granulomatous disease
		Chronic granulomatous disease (CGD) is transmitted as a sex-linked recessive trait.
		CGD is almost universally a disease affecting males, although it is possible for a woman to have two affected X chromosomes and subsequently develop CGD.
		In this disease, the inability of phagocytic cells to kill certain bacteria and fungi leads to long term (chronic) and repeated (recurrent) infections appearing in the first years of life.
	www.enlmedical.com /article/001239.htm (364 words)

	Chronic Granulomatous Disease (Site not responding. Last check: 2007-11-06)
		Chronic granulomatous disease is a term used to describe the group of inherited disorders of the immune system characterized by an inability of the body’s phagocytes to kill certain micro-organisms.
		Patients with chronic granulomatous disease have an increased susceptibility to infection with staphylococcus, gram-negative bacteria and fungi.
		All patients with chronic granulomatous disease are at risk of infections of the lymph nodes, skin, lungs and bones.
	www.stjude.org /disease-summaries/0,2557,449_2164_6530,00.html (365 words)

	Nocardia farcinica Pneumonia in Chronic Granulomatous Disease -- Shetty et al. 104 (4): 961 -- Pediatrics
		Chronic granulomatous disease (CGD) is a rare inherited disorder of the nicotinamide adenine dinucleotide phosphate-oxidase
		Curnutte JT Chronic granulomatous disease: the solving of a clinical riddle at the molecular level.
		Johnston HC, Shigeoka AO, Hurley DC, Pysher TJ Nocardia pneumonia in a neonate with chronic granulomatous disease.
	pediatrics.aappublications.org /cgi/content/full/104/4/961 (2002 words)

	Chronic Granulomatous Disease
		Chronic Granulomatous Disease is a genetically determined (inherited) primary immune deficiency disease characterized by an inability of the body’s phagocytic cells (polymorphonuclear leukocytes and monocytes) to kill certain microorganisms.
		DEFINITION: Chronic Granulomatous Disease (CGD) is a genetically determined (inherited) disease characterized by an inability of the body’s phagocytic cells to kill certain microorganisms.
		The diagnosis of CGD is made by analyzing the metabolic function and killing capacity of the patient’s phagocytic cells.
	www.immunedisease.com /US/patients/IDF/cgd.html (1423 words)

	CGD Information
		Chronic granulomatous disease is the name given to a collection of inherited genetic mutations that disrupt the NADPH oxidase complex.
		The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex.
		X-Linked Chronic Granulomatous Disease: Mutations in the CYBB Gene Encoding the gp91-phox Component of Respiratory-Burst Oxidase.
	www.bio.davidson.edu /Courses/Immunology/Students/spring2000/bishop/restricted/cgd.html (1396 words)

	Chronic Granulomatous Disease
		ACTIMMUNE or interferon gamma-1b, a form of interferon gamma, is indicated for use in chronic granulomatous disease (CGD) and severe, malignant osteopetrosis.
		Chronic Granulomatous Disease - Chronic granulomatous disease (CGD), an inherited disorder of phagocytic cells, results from an inability of phagocytes to undergo the respiratory burst necessary to...
		Chronic Granulomatous Disease Research Advances on Several Fronts Less than 20 years ago, a child born with chronic granulomatous disease (CGD) had a slim chance of surviving to adulthood.
	www.jrzb.com.cn /35533-chronicgranulomatousdisease.html (245 words)

	eMedicine - Chronic Granulomatous Disease : Article by Lawrence C Wolfe, MD
		CGD is now known to be caused by a defect in the nicotinamide adenine dinucleotide phosphate (reduced form) (NADPH) oxidase enzyme of phagocytes.
		Chronic or recurrent infections in childhood can lead to failure to thrive with impairment of physical growth, though most adults with CGD appear to attain their expected growth potential.
		Granulomatous involvement of the GI and GU tracts is not uncommon.
	www.emedicine.com /ped/topic1590.htm (5738 words)

	Chronic Granulomatous Disease (CGD) - Patient UK
		Chronic granulomatous disease is a genetically heterogeneous immunodeficiency disorder resulting from an inability of phagocytes to kill microbes that they have ingested.
		Serious disease is rarely autosomal dominant as it is self-destructive in that it kills the affected person before he or she can reproduce.
		De Boer M, Bolscher BG, Sijmons RH, et al; Prenatal diagnosis in a family with X-linked chronic granulomatous disease with the use of the polymerase chain reaction.
	www.patient.co.uk /showdoc/40001725 (1407 words)

	Chronic Granulomatous Disease Research Advances on Several Fronts, January 1996
		There are now four known inherited forms of the disease, and the central defect has been identified as the inability of white blood cells called phagocytes to make hydrogen peroxide, which kills certain microbes.
		Five young adults with one form of CGD are undergoing gene therapy in a study at the NIH Clinical Center in Bethesda, Md. This is the first non-AIDS gene therapy trial pioneered by intramural NIAID investigators, and the first attempt worldwide to treat CGD patients with this novel therapy.
		The registry also will also benefit CGD patients and their physicians by providing the first good estimates of the number of people with CGD and new information about the natural history of the disease and its treatment.
	www.niaid.nih.gov /publications/dateline/0196/page3.htm (1407 words)

	National Primary Immunodeficiency ResourceCenter (Site not responding. Last check: 2007-11-06)
		Chronic Granulomatous Disease is an inherited disorder characterized by a defect in which neutrophils (white blood cells in the body that kill invading bacteria or fungus) are unable to kill certain microorganisms.
		When a diagnosis of Chronic Granulomatous Disease is suspected in child with serious infections at an early age, confirmation of this diagnosis is by laboratory analysis.
		There is no specific corrective therapy for patients with Chronic Granulomatous Disease, although bone marrow transplantation has been done in a few cases and is being considered in many centers as an option.
	npi.jmfworld.org /patienttopatient/index.cfm?section=patienttopatient&content=syndromes&area=7&CFID=1293888&CFTOKEN=79674585 (1281 words)

	Chronic Granulomatous Disease: Immunodeficiency Disorders: Merck Manual Professional
		More than 50% of cases of chronic granulomatous disease (CDG) are inherited as an X-linked recessive trait and thus occur only in males; in the rest, inheritance is autosomal recessive.
		CGD usually begins with recurrent abscesses during early childhood, but in a few patients, onset is delayed until the early teens.
		Multiple granulomatous lesions occur in the lungs, liver, lymph nodes, and GI and GU tract (causing obstruction).
	www.merck.com /mmpe/sec13/ch164/ch164e.html (435 words)

	Scedosporium apiospermum in chronic granulomatous disease treated with an HLA matched bone marrow transplant -- Gompels ...
		Scedosporium apiospermum in chronic granulomatous disease treated with an HLA matched bone marrow transplant -- Gompels et al.
		Steroid-responsive esophageal obstruction in a child with chronic granulomatous disease (CGD).
		Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft.
	jcp.bmjjournals.com /cgi/content/full/55/10/784 (1377 words)

	Introduction: Chronic Granulomatous Disease - CureResearch.com
		Chronic Granulomatous Disease: The CGD patient's defense system is not effective against certain bacteria and fungi, including E. coli and Staphylococcus aureus, as well as less common germs like Pseudomonas, Serratia, and Aspergillus.
		Researching symptoms of Chronic Granulomatous Disease: Further information about the symptoms of Chronic Granulomatous Disease is available including a list of symptoms of Chronic Granulomatous Disease, other diseases that might have similar symptoms in differential diagnosis of Chronic Granulomatous Disease, or alternatively return to research other symptoms in the symptom center.
		Statistics and Chronic Granulomatous Disease: Various sources and calculations are available in statistics about Chronic Granulomatous Disease, prevalence and incidence statistics for Chronic Granulomatous Disease, and you can also research other medical statistics in our statistics center.
	www.cureresearch.com /c/chronic_granulomatous_disease/intro.htm (294 words)

	ACTIMMUNE ®: Chronic Granulomatous Disease (Site not responding. Last check: 2007-11-06)
		Chronic granulomatous disease (CGD) is actually a group of rare, inherited disorders of the immune system that are caused by defects in the immune system cells called phagocytes.
		The National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), conducts and supports research on a wide range of allergic, immunologic, and infectious diseases.
		An excellent source of information for patients and families is the Chronic Granulomatous Disease homepage (A Guide for CGD Patients and Their Families).
	www.actimmune.com /wt/act/cgd (846 words)

	Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor -- Myrup et al. 42 ...
		Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor -- Myrup et al.
		In several diseases there is a relation between deficiency of neutrophil granulocytes and granulomatous lesions.
		Agents responsible for infection in chronic granulomatous disease of childhood.
	gut.bmjjournals.com /cgi/content/full/42/1/127 (1551 words)

	Chronic granulomatous disease (Disease) - Des Moines, Iowa Health Hospital IA (Site not responding. Last check: 2007-11-06)
		Chronic granulomatous disease (Disease) - Des Moines, Iowa Health Hospital IA To search for a specific phrase enclose that phrase in quotes.
		Prolonged antibiotic therapy may help to reduce infections, but premature death is typically a result of repeated pulmonary infections.
		Call your health care provider if you have chronic granulomatous disease and you suspect that you have pneumonia or infection in another part of the body.
	www.iowahealth.org /12701.cfm (594 words)

	Granulomatous Disease, Chronic Synonyms, Eastern North Carolina, NC
		Granulomatous Disease, Chronic Synonyms, Eastern North Carolina, NC To search for a specific phrase enclose that phrase in quotes.
		It is possible that the main title of the report Granulomatous Disease, Chronic is not the name you expected.
		Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (lymphocytes).
	www.uhseast.com /112930.cfm (433 words)

	Statistics about Chronic Granulomatous Disease - WrongDiagnosis.com
		The term 'prevalence' of Chronic Granulomatous Disease usually refers to the estimated population of people who are managing Chronic Granulomatous Disease at any given time.
		The term 'incidence' of Chronic Granulomatous Disease refers to the annual diagnosis rate, or the number of new cases of Chronic Granulomatous Disease diagnosed each year.
		Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence.
	www.wrongdiagnosis.com /c/chronic_granulomatous_disease/stats.htm (253 words)

	MedlinePlus Medical Encyclopedia: Chronic granulomatous disease
		CGD; Fatal granulomatosis of childhood; Chronic granulomatous disease of childhood; Progressive septic granulomatosis
		Chronic granulomatous disease is an inherited abnormality of certain cells of the immune system, known as phagocytic cells.
		Chronic granulomatous disease (CGD) is transmitted in 50%-60% of the cases as a recessive sex-linked trait.
	www.nlm.nih.gov /medlineplus/ency/article/001239.htm (646 words)

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