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Topic: Chronic myeloid leukaemia

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	Chronic Myeloid Leukaemia
		Chronic myeloid leukaemia is a form of leukaemia that progresses slowly during the chronic phase of the disease.
		In chronic myeloid leukaemia the disease is typically widespread at the time of diagnosis, which is why this form of staging is not used.
		Chronic myeloid leukaemia is a form of leukaemia affecting a primitive stem cell.
	www.lrf.org.uk /en/1/infdispatcml.html (5834 words)

	Chronic Myelogenous Leukemia Treatment - National Cancer Institute
		Chronic myelogenous leukemia (CML) is one of a group of diseases called the myeloproliferative disorders.
		Deininger MW, Goldman JM, Melo JV: The molecular biology of chronic myeloid leukemia.
		Martiat P, Michaux JL, Rodhain J: Philadelphia-negative (Ph-) chronic myeloid leukemia (CML): comparison with Ph+ CML and chronic myelomonocytic leukemia.
	www.cancer.gov /cancerinfo/pdq/treatment/CML/healthprofessional (392 words)

	Chronic Myeloid Leukaemia (CML) - Patient UK
		Chronic myeloid leukaemia is a cancer of blood forming cells in the bone marrow.
		CML is sometimes called chronic myelogenous leukaemia, chronic granulocytic leukaemia, or chronic myelocytic leukemia.
		Chronic myeloid leukaemia (CML) is the rarest of the four main types of leukaemia.
	www.patient.co.uk /showdoc/27000839 (2268 words)

	indiacancer.org - Chronic Myeloid Leukaemia (Site not responding. Last check: 2007-10-23)
		CML or chronic myeloid leukaemia is a slowly progressive leukaemia and usually occurs in people who are middle aged or older than that, but it can also be seen sometimes in children.
		CML being an insidious disease, progresses very slowly and initially there may be no symptoms at all.
		CML once diagnosed may have to be evaluated to check if there is involvement of the central nervous system or the brain.
	www.indiacancer.org /coca/c/chronic.html (2524 words)

	The treatment of chronic myeloid leukaemia
		Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder characterized by leukocytosis with accumulation of all forms of mature and immature granulocytes.
		It is the hallmark of CML and is found in 95% of patients.
		P53 loss and point mutations are associated with suppression of apoptosis and progression of CML to myeloid blast crisis.
	www.priory.com /med/leuk.htm (3167 words)

	ABC of clinical haematology: Chronic myeloid leukaemia -- Goldman 314 (7081): 657 -- BMJ (Site not responding. Last check: 2007-10-23)
		Chronic myeloid leukaemia is a clonal malignant myeloproliferative
		The diagnosis of chronic myeloid leukaemia in chronic phase
		Peripheral blood film from patient with chronic myeloid leukaemia showing many mature granulocytes, including two basophils (arrow); a blast cell is prominent (double arrow).
	bmj.bmjjournals.com /cgi/content/full/314/7081/657 (1608 words)

	myeloid leukaemia (chronic) - General Practice Notebook
		Chronic myeloid leukaemia is a malignant clonal proliferation of an abnormal haemopoietic stem cell.
		Chronic myeloid leukaemia accounts for 20% of all leukaemias.
		It occurs mainly in middle aged and elderly people and is characterised by marked leucocytosis, a left shifted myeloid series and in 95% of patients, the Philadelphia chromosome.
	www.gpnotebook.co.uk /simplepage.cfm?ID=87359532 (881 words)

	Chronic Myeloid Leukaemia
		Chronic myeloid leukaemia (CML) affects the myeloid cells in the blood, that is all the blood cells except the lymphocytes.
		The word chronic describes the comparatively sluggish progress of the disease if left untreated.
		Most patients with chronic myeloid leukaemia can be treated effectively with anti-cancer drugs.
	www.lrf.org.uk /en/1/discmlhome.html (99 words)

	Leukaemia (chronic myeloid) - imatinib (No. 70)
		NICE has recommended that imatinib should be the first treatment considered for an adult with the Philadelphia-chromosome type of CML in the chronic phase.
		If a person has been taking imatinib for CML while in the chronic phase, but still goes on to the accelerated or blast crisis phase, NICE has recommended that imatinib treatment is continued only as part of a research study.
		If a person in the chronic phase of CML is already taking interferon-alpha, the choice about whether to change to imatinib depends to some extent on how well the interferon-alpha is working and how well the person is feeling.
	www.nice.org.uk /page.aspx?o=89859 (315 words)

	Leukaemia (chronic myeloid) - imatinib (No. 50) obsolete, replaced by No. 70
		Leukaemia (chronic myeloid) - imatinib (No. 50) obsolete, replaced by No. 70
		Please note that this appraisal has now been reviewed and the guidance replaced by Leukaemia (chronic myeloid) - imatinib (No. 70).
		Assessment report on the use of imanitib for chronic myeloid leukaemia
	www.nice.org.uk /cat.asp?c=37604 (96 words)

	Chronic Myeloid Leukaemia - Genetics
		-Monitoring of of ABL-BCR in Patients with CML in Remission
		Chronic myelogenous leukemia (CML) is characterised by the Philadelphia (Ph) chromosome which is seen in over 95% of patients.
		The median age of patients with Ph+ CML is 67 years of age, it can occasionally occur in children (2-3% of all childhood leukaemias).
	www.cancerindex.org /geneweb/X1208.htm (140 words)

	Statements of Principles - Chronic myeloid leukaemia - diagnostic protocol
		Statements of Principles - Chronic myeloid leukaemia - diagnostic protocol
		The diagnosis of chronic myeloid leukaemia can be confirmed when made by an LMO, specialist or Departmental medical officer as a final diagnosis.
		Before confirming the diagnosis you should be satisfied that the claimed condition falls within the scope of the words in the RMA SOP definition of chronic myeloid leukaemia (Instruments No. 15 and 16 of ’03).
	www.dva.gov.au /pensions/statemnt/b016dp.htm (111 words)

	leukaemia (chronic myeloid, juvenile) - General Practice Notebook
		leukaemia (chronic myeloid, juvenile) - General Practice Notebook
		Juvenile CML is thought to originate from a mutation in a foetal stem cell.
		It is a rare disorder and affects children under 5 years of age.
	www.gpnotebook.co.uk /medwebpage.cfm?ID=-294977530 (798 words)

	Chronic Myeloid Leukaemia: Biology and Treatment (Site not responding. Last check: 2007-10-23)
		Book Description: In this volume, an international team of experts in chronic myeloid leukemia share their expertise.
		In particular, they contribute their insights on the latest advances in understanding this disease, and the implications those developments have for its management.
		Chronic Myeloid Leukemia is ideal for oncologists and other specialists in the field.
	isbn.nu /185317890X (378 words)

	Leukemia, Myeloid, Chronic
		The booklet explains the causes, signs and symptoms, diagnosis, treatment, and prognosis of chronic myeloid leukaemia.
		A collection of resources on chronic myeloid leukaemia including statistics, and access to relevant guidelines, further reading, Medline searches, papers, trials, patient information, and other resources (including Web sites).
		Using diagrammatical information the leaflet explains what leukaemia is, the main types of leukaemia together with specific details about chronic myeloid leukaemia and who gets it.
	omni.ac.uk /browse/mesh/D015464.html (521 words)

	Chronic myeloid leukaemia (CML)
		This section of CancerHelp UK tells you about chronic myeloid leukaemia (CML).
		It includes symptoms and causes, treatment for chronic myeloid leukaemia, living with chronic myeloid leukaemia, and current research.
		CancerHelp UK is not designed to provide medical advice or professional services and is intended to be for educational use only.
	www.cancerhelp.org.uk /help/default.asp?page=4830 (103 words)

	Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
		Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
		The presence of an abnormally small chromosome (Ph/sup 1) replacing one of the smallest acrocentric autosomes is looked for in blood cells of two patients with chronic myeloid leukemia.
		The Ph/sup 1/ is observed in about half the cells of one of the patients, who has received no treatment for the disease.
	www.osti.gov /energycitations/product.biblio.jsp?osti_id=4789874 (187 words)

	Suggested links for Chronic myeloid leukaemia Diseases Database (Site not responding. Last check: 2007-10-23)
		CML overview of prognosis, diagnosis, classification, and patient treatment
		Leukaemia (chronic myeloid) - imatinib for first line therapy (No 70)
		Content is not asserted complete or error free, please see also our disclaimer.
	www.diseasesdatabase.com /links1.asp?glngUserChoice=2659 (117 words)

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