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Topic: Cinchophen


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In the News (Thu 24 Dec 09)

  
  cinchophen
Cinchophen is an analgesic drug that was introduced in 1910 and frequently used to treat gout.
This drug is still used somewhat by veterinarians to treat gout.
Use of this drug in humans ceased in the 1930's due to the discovery that cinchophen can cause serious liver damage.
www.measuroo.com /dru-C/cinchophen.php   (48 words)

  
 Cinchophen at The Medical Dictionary
Cinchophen derivatives containing arsenic;: Some new types of organic bismuth compounds,
Cinchophen derivatives containing arsenic;: Arsenic derivatives of the diphenyl series,
The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and acridine dyes;: The relation between their chemical constitution...
the-medical-dictionary.com /cinchophen.htm   (99 words)

  
 THE ACTION OF CINCHOPHEN -- GRABFIELD and PRATT 42 (4): 407 -- Journal of Pharmacology And Experimental Therapeutics
cinchophen day when compared with the endogenous level was increased
by cinchophen were tabulated in thirteen of the persons studied.
of cinchophen is solely on the kidneys increased excretion of
jpet.aspetjournals.org /cgi/content/abstract/42/4/407   (590 words)

  
 Arthritis And Rheumatism
The most dangerous of these drugs is cinchophen or, as it is sometimes called, atophan.
This drug, incorporated in many patent medicines or administered as such, has been responsible for many deaths and a far greater number of serious illnesses.
The dangers in the use of cinchophen are so well recognized now that the U. government has at last been empowered to proceed against those cinchophen-containing preparations which are "dangerous to health when used in the dosage, or with the frequency or duration prescribed, recommended or suggested in the labeling thereof."
www.oldandsold.com /articles35/health-and-medicine-49.shtml   (1007 words)

  
 Gout
Being not only effective in the acute attacks but, unlike colchicine, also an analgesic, cinchophen virtually replaced colchicine until it became evident in the 1930s that it caused liver damage.
Probenecid was found to accelerate excretion of uric acid; the frequency of gout attacks diminished and tophi shrank.
The other discovery was phenylbutazone, with therapeutic effects similar to cinchophen.
partners.nytimes.com /books/first/p/porter-gout.html   (4117 words)

  
 DRUG-INDUCED SKIN ERUPTIONS
cinchophen, meprobamate, penicillin, silvestrol, sulphonamides, ACE-inhibitors (see also urticaria).
acetylsalicylic acid, antipyrins, arsenic, barbiturates, bromides, chloral hydrate, chlorpromazine, cinchophen, cumarin, phenytoin, hydantoin, iodides, mesantoin, phenobarbital, promethazine, sodium thiosulphate, sulfamethoxypyridazine, sulphonamides, tetracycline.
barbiturates, cinchophen, mercury, morphine, novobiocin, opium, penicillin, phenobarbital, pituitary extract, quinine, salicylates, streptomycin, sulphonamides, atropine.
www.cverros.gr /Drugerup.htm   (1289 words)

  
 Pyridylmethyl esters of selected bio-affecting carboxylic acids - Patent 4376767
A compound as defined by claim 1, wherein R--COO-- is the acyloxy residue of a monocarboxylic acid selected from the group consisting of indomethacin, aspirin, naproxen, sulindac, ibuprofen, tolmetin, diflunisal, flurbiprofen, indoprofen, fenclozic acid, ketoprofen, alclofenac, bucloxic acid, cinchophen, cinmetacin, ibufenac, furoburen, prodolic acid, pirprofen, fluprofen, flutiazin, clometacin, flufenisal and salsalate.
A compound as defined by claim 34, wherein R--COO-- is the acyloxy residue of cinchophen.
Other objects, features and advantages of the invention will be apparent to those skilled in the art from the detailed description of the invention which follows.
www.freepatentsonline.com /4376767.html   (7687 words)

  
 Pethealthcare - Pet Guide - Pet Clinic - My dog, Gemma, has spondolitis in her back ...
It may be that Gemma has additional problems that are causing the continual discomfort when walking and getting up.
Prednolucotropin is a combination of a steroid, prednisolone and a non-steroidal anti-inflammatory (NSAID), cinchophen.
It is a good painkiller but you must be careful when using it in combination with additional steroid tablets, as I am sure your vet will have discussed with you.
www.pethealthcare.co.uk /question_1031   (350 words)

  
 Question of the Week - International Veterinary Academy of Pain Management - Colorado State University   (Site not responding. Last check: 2007-10-11)
The gastroduodenal mucosa of 30 healthy dogs was examined by endoscope after 7 days of oral non-steroidal anti-inflammatory drug administration.
One group received ketoprofen (1 mg/kg every 24 h), one group copper-indomethacin (0.2 mg/kg every 12 h), one group 1 mg of prednisolone and 200 mg of cinchophen (1 tablet/20 kg every 12 h), one group aspirin (15 mg/kg every 12 h) and one group gelatin (1 capsule every 12 h).
Occult blood was not detected in the faeces either before or after non-steroidal anti-inflammatory drug administration.
cvmbs.colostate.edu /ivapm/professionals/members/qow/aspirinarticle.htm   (985 words)

  
 [No title]
Atophan (2-phenylquinoline-4-carboxylic acid) or cinchophen is recommended for budgerigars, 120 mg SID, and for fowl, 250 mg BID.
Low-protein seed mixtures should be provided, along with a rich supply of vegetables & fruit, supplemented vit A. For general treatment, give sodium bicarbonate (0.5 to 2%) or lithium carbonate (1%).
Atophan (2-phenylquinoline-4-carboxylic acid) or cinchophen is recommended for budgerigars, 120 mg SID, & for fowl, 250 mg BID.
netvet.wustl.edu /species/birds/aviandis.txt   (6581 words)

  
 cinchophen - OneLook Dictionary Search   (Site not responding. Last check: 2007-10-11)
We found 4 dictionaries with English definitions that include the word cinchophen:
Tip: Click on the first link on a line below to go directly to a page where "cinchophen" is defined.
cinchophen : Stedman's Online Medical Dictionary, 27th Edition [home, info]
onelook.com /?w=cinchophen   (86 words)

  
 STUDIES ON THE DENERVATED KIDNEY I. THE ACTION OF CINCHOPHEN ON THE URIC ACID AND ALLANTOIN EXCRETION IN DOGS, AND ITS ...
The effects of cinchophen on the uric acid and allantoin
effect of cinchophen on the uric acid excretion after denervation
by the exhibition of cinchophen is not altered by denervation
jpet.aspetjournals.org /cgi/content/abstract/50/1/123   (188 words)

  
 FDA Law Enforcement: Critical to Product Safety
Instead, the government acted against other obesity products such as Marmola, which contained thyroid extract, a potent drug that the agency had been unable to take action against under the 1906 act.
Pain relievers and headache remedies containing aminopyrine and cinchophen and a mixture of acetanilide and bromides were soon seized based on misbranding charges.
Because the 1938 act contained many new sections that applied to the food industry, Junod says that the early inspectors recall they spent a lot of time in the field taking industry surveys.
www.fda.gov /fdac/features/2006/106_ora.html   (3062 words)

  
 Find in a Library: The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and ...
Find in a Library: The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and acridine dyes; the relation between their chemical constitution and pharmacologic action,
The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and acridine dyes; the relation between their chemical constitution and pharmacologic action,
WorldCat is provided by OCLC Online Computer Library Center, Inc. on behalf of its member libraries.
www.worldcatlibraries.org /wcpa/ow/08beb2eabf248afb.html   (124 words)

  
 Definition of cinchophen - Merriam-Webster Online Dictionary
Click here to search for another word in the Merriam-Webster Online Dictionary.
Visit Britannica.com for more information on "cinchophen "
Get the Top 10 Search Results for "cinchophen "
m-w.com /dictionary/cinchophen   (29 words)

  
 Amazon.com: The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and acridine ...   (Site not responding. Last check: 2007-10-11)
Amazon.com: The therapeutic agents of the quinoline group, cinchophen, plasmoquine, nupercaine, quinine and acridine dyes;: The relation between their chemical constitution...
This item is not eligible for Amazon Prime, but over a million other items are.
If you would like to purchase this title, we recommend that you occasionally check this page to see if it has become available.
www.amazon.com /exec/obidos/ASIN/B00085JWGU/ref=pd_smaj_1121903609   (481 words)

  
 Interpretation of Lab Test Profiles / Cushing's Help and Support   (Site not responding. Last check: 2007-10-11)
Generally, fasting blood glucose >140 mg/dL and/or 2h postprandial glucose >200 mg/dL demonstrated on several occasions is suggestive of diabetes mellitus; OGTT is usually not required for diagnosis.
In adults, hypoglycemia can be observed in certain neoplasms (islet cell tumor, adrenal and gastric carcinoma, fibrosarcoma, hepatoma), severe liver disease, poisonings (arsenic, CCl4, chloroform, cinchophen, phosphorous, alcohol, salicylates, phenformin, and antihistamines), adrenocortical insufficiency, hypothroidism, and functional disorders (postgastrectomy, gastroenterostomy, autonomic nervous system disorders).
Failure to promptly separate serum from cells in a red top tube causes falsely depressed glucose levels.
www.cushings-help.com /results.htm   (4430 words)

  
 Amazon.com: "hepatotoxic threat": Key Phrase page   (Site not responding. Last check: 2007-10-11)
See all pages with references to hepatotoxic threat.
Cinchophen has long since fallen from clinical use, and its hepatotoxic threat is no longer relevant.
However, the adverse effects of NSAIDs have again become the focus of attention (...
www.amazon.com /phrase/hepatotoxic-threat   (295 words)

  
 Amazon.com: "been hepatocellular": Key Phrase page   (Site not responding. Last check: 2007-10-11)
See all pages with references to been hepatocellular.
Only glafenine, diclofenac, and cinchophen have provoked significant hepatic disease in sufficient numbers to be meaningful; and the injury has been hepatocellular.
Key Phrases in this book: Clin Pharmacol, Arthritis Rheum, Ann Intern Med, Agents Actions, Ann Rheum Dis, United States, migraine abortive therapy, pravadoline maleate, drug exanthem, gastric irritancy, leflunomide therapy, phenazone derivatives (See more)
www.amazon.com /phrase/been-hepatocellular   (298 words)

  
 Cytochrome P450s and Other Enzymes in Drug Metabolism and Toxicity
To return to the issue, there is another list of drugs with reactive products that have warnings for hepatoxicity: acetaminophen (Figure 5), carbamazepine, clozapine, diclofenac, disulfiram, halothane, leflunomide, methyldopa, rifampin, tacrine, tamoxifen, terbinafine, ticlopidine, and zileuton.
Another list in the same reference includes drugs with reactive metabolites that were used in other countries but never approved in the United States: alpidem, amineptine, amodiaquine, cinchophen, dihydralazine (Figure 6), dilevalol, ebrotidine, glafenine, ibufenac, isoxicam, niperotidine, perhexiline, pirprofen, and tilbroquinol.
The point has been made several times that the drugs associated with apparently idiosyncratic reactions are not really dose-independent.
www.aapsj.org /view.asp?art=aapsj080112   (5465 words)

  
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oldach.net /maze/Convolvulad/tied/blately   (420 words)

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