| | Distribution of protein disulfide isomerase in rat epiphyseal chondrocytes. (Site not responding. Last check: 2007-10-30) |
 | | The labeling density of the cisternal space of the dilated ER, probably reflecting marked accumulation of secretory proteins such as procollagen, was always higher than that of the non-dilated ER. |
 | | In the dilated cisternal space, gold particles were freely and evenly distributed, without preferential binding to the luminal surface of the ER membranes. |
 | | The exclusive localization of gold particles in the cisternal space of the ER and nuclear envelopes and the lack of gold particles in the Golgi apparatus, including cis-Golgi cisternae, indicate that PDI is an ER-soluble protein in the chondrocytes and is presumably sorted out in some pre-Golgi compartment and not transported to the Golgi apparatus. |
| www.arclab.org /medlineupdates/abstract_2584692.html (236 words) |