
	Where results make sense

Topic: Click chemistry

	C&EN: COVER STORY - IN SITU CLICK CHEMISTRY
		Click chemistry is the use of chemical building blocks with "built-in high-energy content to drive a spontaneous and irreversible linkage reaction with appropriate complementary sites in other blocks," explains Scripps chemistry professor and Nobel Laureate K.
		An important chemical precedent for in situ click chemistry was a series of classic experiments in the 1980s by chemistry professor William L. Mock of the University of Illinois, Chicago, and coworkers on cucurbituril--a nonadecacyclic cage structure that acts as a catalyst.
		In the nonbiological area, Sharpless, Finn, and coworkers are collaborating with groups led by chemistry professors Paul S. Weiss and Raymond L. Funk of Penn State and James M. Tour of Rice University in an effort to develop surfaces with precise chemical patterns at the nanometer scale.
	pubs.acs.org /cen/coverstory/8006/8006clickchemistry.html (2432 words)

	Click chemistry - Wikipedia, the free encyclopedia
		Click chemistry is a concept introduced by K.
		Barry Sharpless in 2001 and describes chemistry tailored to generate substances quickly and reliably by joining small units together as nature does.
		Click chemistry in combination with combinatorial chemistry, high-throughput screening and building chemical libraries speeds up new drug discoveries by making each reaction in a multistep synthesis fast, efficient and predictable.
	en.wikipedia.org /wiki/Click_chemistry (377 words)

	chemistry encyclopedia (Site not responding. Last check: 2007-10-26)
		Written for a broad, cross-disciplinary audience, the Encyclopedia of Biological Chemistry addresses the fundamental discipline of biological chemistry underlying virtually all of the life sciences.
		In its short (30 year) history, computational chemistry has become one of the mainstays of modern industrial and academic chemistry.
		Examines the six major areas of inorganic chemistry: physical and theoretical methods, organometallic chemistry, main group elements, solid state chemistry, transition metals and bioinorganic chemistry.
	www.books-n-magazines.com /mkw/chemistry_encyclopedia.html (519 words)

	The Scripps Research Institute - News and Views
		Click chemistry, a modular protocol for organic synthesis that Sharpless developed, is a powerful and original approach to drug design.
		These protein-protein interfaces often have multiple potential binding sites for small molecules, and the trick with in situ click chemistry is to find classes of compounds that will bind tightly enough in the two faces of HIV that their proximity will allow their natural reactivity to take over.
		In this case, in vivo in situ click chemistry suggests the development of a new type of cocktail—one that is made inside the target enzymes inside a living organism.
	www.scripps.edu /newsandviews/e_20040202/resistance2.html (1054 words)

	Chemistry
		Chemistry is the study of matter and the interactions among different types of matter.
		Chemistry is the study of the atomic building blocks of nature, how they combine and their combinations which form the solids, liquids, and gases that make up most forms of matter.
		Chemistry is the branch of science concerned with the properties, structure, and composition of substances and their reactions with one another.
	www.101science.com /Chemistry.htm (1826 words)

	Click on to HPLC
		The power of ‘click chemistry’ has been extended to the world of separation analysis by a team of scientists in China.
		The ‘click chemistry’ concept was first referred to in 2001 by Barry Sharpless and co-workers and describes highly efficient approaches to joining molecular units together.
		The team hope they will be able to develop their click columns for the urgent problem of separating the highly complex mixtures of traditional Chinese medicine, said Lei.
	www.rsc.org /Publishing/ChemTech/Volume/2006/12/click_hplc.asp (348 words)

	CEFIC - Global Themes
		Chemistry is a multidisciplinary science which is essential to a wide variety of fields, e.g.
		By contrast, chemistry allows us to make new materials with astounding properties on which our technological world is dependent.
		Chemistry is by definition the transformation of matter.
	www.chemforlife.org /themes (351 words)

	Click Chemistry: A "Click" Away from Discovery
		Even with the advent of combinatorial chemistry and high-throughput screening in the past two decades, the generation of leads is dependent on the reliability of the individual reactions to construct the new molecular framework.
		Click chemistry is a newer approach to the synthesis of drug-like molecules that can accelerate the drug discovery process by utilizing a few practical and reliable reactions.
		Of the reactions comprising the click universe, the “perfect” example is the Huisgen 1,3-dipolar cycloaddition of alkynes to azides to form 1,4-disubsituted-1,2,3-triazoles (Scheme 1).
	www.sigmaaldrich.com /Area_of_Interest/Chemistry/Chemical_Synthesis/Product_Highlights/Click.html (499 words)

	WU Libraries: Chemistry Library
		Click here for a full list of all the Electronic Journals Washington University currently subscribes to.
		Reference services, research consultation, and individual and group instruction in the use of Chemistry Library resources is available either during posted office hours or by appointment.
		One is reserved for Chemistry Department faculty, staff, and students.
	library.wustl.edu /units/chemistry (548 words)

	Chemistry
		Click on the links on the left of the page for a comprehensive treatment of many of the topics required for the Leaving Certificate syllabus.
		Beginning in 1998 the Lapeer East Chemistry II class began publishing the results of some of their experiments and projects on the Internet.
		Chemistry Quizzes have been written for many topics on the chemistry syllabus.
	www.sip.ie /sip069/Documents/chemistrypage.html (1086 words)

	Rader's CHEM4KIDS.COM
		If you're still not sure what to click, try our site map that lists all of the topics on the site.
		Chemistry is the study of MATTER and the changes that take place with that matter.
		Matter is the name that scientists have given to everything that you can touch, or see, or feel, or smell.
	www.chem4kids.com (326 words)

	Click Chemistry Strategy Test More Than Successful
		The enzyme selected for click chemistry's proof-in-practice was one of the first brain enzymes to be identified.
		Sharpless calls this variation of click chemistry "in situ," which is Latin for "in the natural position." In this case, the reaction is in situ because the enzyme directs which way the pieces come together.
		In click chemistry, chemicals (such as acetylcholinesterase inhibitors) are made from modular chemical "blocks" that can be joined together in various combinations in very few steps.
	unisci.com /stories/20021/0315021.htm (1020 words)

	Windows FAQ
		Your Windows username is identical to your username on the chemistry Unix server, but your Windows password is independent of (and should be different from) your Unix password.
		Your /home directory on chemistry, as well as chemistry's /scr disk are available from any PC running Windows.
		The chemistry Unix server simply forwards connection requests to the Windows server, and the Windows server authenticates the requests (using the Windows password database).
	www.chemistry.ohio-state.edu /compsupp/PC-Mac/nt-accounts.html (1090 words)

	chair for fundamental organic chemistry fct/unl. home page
		The Chair for Fundamental Organic Chemistry is part of the Organic Chemistry Section of the Department of Chemistry The main role is to carry on teaching at the graduate and undergraduate levels on various fields of organic chemistry.
		This course covers the fundamentals of Organic Chemistry for students on the 2nd and 3rd semesters of Organic Chemistry, Biotechnology and Chemical Engineering degrees.
		This course is complementary to Analytical Chemistry as an optional area in the 4th and 5th semesters of the Organic Chemistry, Biotechnology, and Chemical Engineering degrees.
	www.dq.fct.unl.pt /qof/QOF.html (1224 words)

	Barry K. Sharpless - CIRS (Site not responding. Last check: 2007-10-26)
		The Sharpless Lab was the first academic chemistry group with robotics, and the lesson from the combinatorial numbers game was the primacy of reliability.
		"Click" chemistry was the Sharpless Lab's response: a set of powerful, virtually 100% reliable, selective reactions for the rapid synthesis of new compounds via heteroatom links (C-X-C).
		Click chemistry is integral now to all research within the Sharpless Lab.
	www.cirs.net /researchers/Chemistry/sharpless.htm (250 words)

	Instructions for how to access my grades!
		Click on the WebCT link on the previous page (it should still be open as this window should have opened in a new window).
		Click on a WebCT link or type in the address: http://virtual.parkland.edu:8900.
		If you click on the linked name of the score you will get any available statistics for it (like the mean score, et cetera).
	virtual.parkland.edu /kozaneck/chemistry202/grades_instructions.html (220 words)

	Click chemistry
		The method, termed in situ click chemistry, uses the cycloaddition of azides with alkynes as the 'click' mechanism that locks two halves of the desired structure together.
		A combinatorial approach including different lengths of hydrocarbon linker chains between the functional sites and the clicking parts allows chemists to screen several combinations for the optimal geometric arrangement.Sharpless' team used the method to find a new inhibitor of the enzyme acetylcholinesterase (AChE), which plays a key role in the transmission of nerve signals.
		Hartmuth Kolb's group, also at the Scripps Research Institute, has collaborated to extend the range of the method and identified three additional AChE inhibitors.2 The group has expanded this work to the metabolic enzyme carbonic anhydrase (CA), a drug target in the treatment of glaucoma.
	www.rsc.org /chemistryworld/Issues/2005/February/clickchemistry.asp (343 words)

	Chemsongs - Fun & Funny Chemistry Songs
		On the eighth day of chemistry, my teacher said to me, don't touch the equipment, is everyone on time, don't blow up the lab, get off the desks, wear safety glasses, acids are harmful, hydrogen is a gas, and write down the safety rules.
		On the ninth day of chemistry, my teacher said to me, don't throw the glassware, don't touch the equipment, is everyone on time, don't blow up the lab, get off the desks, wear safety glasses, acids are harmful, hydrogen is a gas, and write down the safety rules.
		On the tenth day of chemistry, my teacher said to me, put down the matches, don't throw the glassware, don't touch the equipment, is everyone on time, don't blow up the lab, get off the desks, wear safety glasses, acids are harmful, hydrogen is a gas, and write down the safety rules.
	www.delta.edu /slime/chemsongs.html (1619 words)

	Nobel Laureate Chemist K. Barry Sharpless to Lecture at Pomona College
		Sharpless is the W. Keck Professor of Chemistry at The Scripps Research Institute (TSRI) in La Jolla, Calif. Along with his co-workers, he has discovered and developed many widely used catalytic oxidation processes.
		He previously served on the chemistry faculties of the Massachusetts Institute of Technology (1970and#8211;1977, 1980and#8211;1990, Arthur C. Cope Professor, 1987and#8211;1990) and Stanford University, (1977and#8211;1980).
		He previously served on the chemistry faculties of the Massachusetts Institute of Technology (1970–1977, 1980–1990, Arthur C. Cope Professor, 1987–1990) and Stanford University, (1977–1980).
	www.collegenews.org /x2133.xml (930 words)

	JCE Online: JCE WebWare: Chemistry Formatter Add-ins for Microsoft Word and Excel
		A chemistry formatter is software that does some of the formatting a chemist would otherwise have to do by hand.
		Chemistry formatters for Microsoft Excel and Word are provided that perform the five functions described below.
		Users select the material to be formatted, click the chemistry formatter button, and the reformatted material appears.
	jchemed.chem.wisc.edu /JCEWWW/Features/WebWare/WW004 (333 words)

	Amazon.com: Heathen Chemistry: Music: Oasis (Site not responding. Last check: 2007-10-26)
		Heathen Chemistry is their first step back up the ascent, albeit a small step.
		Perhaps its the fact that "Owen Morris" is not producing their albums anymore, or the fact that they need a producer, because Oasis produced this album themselves, and while thats all well and good.
		Heathen Chemistry is pretty watered down and weak, it does not stand up well as a entire listen and too much of the tracks sound more filler than anyhting else.
	www.amazon.com /exec/obidos/tg/detail/-/B000068QY7?v=glance (1352 words)

	Home Page: Ms Mowbray's AP Chemistry (Site not responding. Last check: 2007-10-26)
		AP Chemistry is a demanding, college level chemistry class.
		Lab is an important component of AP Chemistry.
		Click here for the most recent Problem Set.
	lvillage.wsfcs.k12.nc.us /lv/hscare/hp.nsf/HomePages/lmowbray (152 words)

	Electron Configurations (Site not responding. Last check: 2007-10-26)
		Click on "Overview" This is an overview or review of Chapter 8.
		Click on "Exploration" Click on "The VSEPR Theory of Molecular Structure".
		Click on the molecule and drag the pointer to see the molecule rotate.
	www.nv.cc.va.us /alexandria/science/101LewisStructuresworksheet.html (199 words)

	New Page 1 (Site not responding. Last check: 2007-10-26)
		Then highlight the current chapter from the second drop-down menu and click to open.
		Click on On-line study tools from the list.
		Browse through the “book” on the right by clicking the arrows at the bottom of the page, or by using the scroll bar on the right side.
	www.rock-hill.k12.sc.us /teachers/rhhs/mbailey/test.htm (106 words)

	Professional Development Curriculum at the University of Pittsburgh Department of Chemistry
		Although excellent experimental technique and a broad chemical knowledge are crucial to a career in chemistry, there are additional skills that are needed in order to be truly successful.
		Click here to view various opportunities for career devlopment outside of University of Pittsburgh.
		Click here to view a listing of various available chemistry positions that have been brought to our attention.
	www.chem.pitt.edu /grad/procurriculum.asp (320 words)

	Department of Chemistry & Biochemisty: Current News and Events
		The award recognized his accomplishments in bio-inorganic chemistry, specifically his investigations of oxygen activating heme enzymes and the use of spectroscopy to determine the coordination structure of heme centers in proteins.
		Inorganic Chemistry is the most widely cited and respected journal in its field with articles covering a broad spectrum of interests including bioinorganic, organometallic, solid state and materials chemistry and the chemistry of nanoscale systems.
		His current research efforts are in the areas of inorganic and organometallic chemistry including synthesis, structures, and catalytic properties of bimetallic clusters and nanoparticles; as well as studies of heterocyclic macrocycles; and molecular electronics.
	www.chem.sc.edu /NewsArchive.asp (6907 words)

	ACS-Fluorine Division Home
		Click on Newsletter in the menu bar to the left.
		Donations are sought for the Moissan Summer Undergraduate Research Fellowship in Fluorine Chemistry, administered by the ACS Division of Fluorine Chemistry.
		Click here to download a pdf version of the bylaws.
	membership.acs.org /F/FLUO (413 words)

	The page cannot be found (Site not responding. Last check: 2007-10-26)
		Make sure that the Web site address displayed in the address bar of your browser is spelled and formatted correctly.
		If you reached this page by clicking a link, contact the Web site administrator to alert them that the link is incorrectly formatted.
		Click the Back button to try another link.
	www.absoluteastronomy.com /encyclopedia/c/co/computational_chemistry.htm (121 words)

	ASU Libraries: Chemistry Links
		Chemdex: Biochemistry and Biological Chemistry and Chemdex: Bioinorganic Chemistry
		Jobs can be searched by categories such as analytical chemistry, applied chemistry, biochemistry, cancer research, catalysis, chemical engineering, chemistry, computational chemistry, drug discovery, education, environmental chemistry, inorganic chemistry, materials science, medicinal and pharmaceutical chemistry, nuclear chemistry, organic chemistry, pharmacology, physical chemistry, spectroscopy, and theoretical/computational chemistry.
		Chemistry books will be found under QD (chemistry), although some chemical physics titles may be found under QC (physics), and some biochemistry may be found under QP (biochemistry).
	www.asu.edu /lib/noble/chem/chem-links.htm (3414 words)

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