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Topic: Coloboma

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	BBC - Health - Ask the doctor - Coloboma
		Coloboma is a condition where the eye fails to develop fully while the baby is in the womb, leaving part of the structure of the eye missing (usually at the bottom of the eye).
		In the most common type of coloboma, this natural cleft fails to close, leaving a split in the iris, lens, the network of blood vessels to the retina (the choroid), the major nerves at the back of the eye, or even the eyelid.
		Coloboma is not one single condition, but a result of a variety of genetic or developmental problems.
	www.bbc.co.uk /health/ask_the_doctor/coloboma.shtml (547 words)

	optic-coloboma.html
		Coloboma involving the optic disc, sclerocornea, persistent pupillary membrane, hypoplasia of iris stroma, and Dandy-Walker syndrome were thought to be caused by the abnormal development of neural crest cells.
		CONCLUSION: Central visual acuity in children born with colobomas involving the optic nerve correlates with the development of normal foveal anatomy, regardless of the size of the coloboma, the color of the optic nerve, or the presence of subfoveal pigmentary changes.
		AB: Coloboma of the lens is characterized by notching of the equator of the lens.
	www.indiana.edu /~pietsch/optic-coloboma.html (8213 words)

	MedlinePlus Medical Encyclopedia: Coloboma of the iris
		Coloboma of the iris is a congenital (present since birth) defect of the iris of the eye.
		Coloboma of the iris may appear as a fl, round hole located in or adjacent to the iris (colored portion of the eye).
		A small coloboma, especially if it is not attached to the pupil, may allow a secondary image to focus on the back of the eye, causing a ghost image, blurred vision, or decreased visual acuity.
	www.nlm.nih.gov /medlineplus/ency/article/003318.htm (487 words)

	Coloboma Information on Healthline
		Coloboma, also known as keyhole defect of the iris, is a congenital genetic disorder that affects the iris of the eye.
		A coloboma describes a condition wherein a portion of a structure of the eye is absent, usually the iris, retina, or the optic nerve.
		The disorder is often referred to as a keyhole defect of the iris because the shape of the coloboma appears as the shape of a keyhole or an upside-down pear.
	www.healthline.com /galecontent/coloboma (628 words)

	Coloboma of the iris
		Coloboma of the iris is a congenital (present since birth) defect of the iris of the eye.
		Coloboma of the iris may appear as a fl, round hole located in or adjacent to the iris (colored portion of the eye).
		A small coloboma, especially if it is not attached to the pupil, may allow a secondary image to focus on the back of the eye, causing a ghost image, blurred vision, or decreased visual acuity.
	www.healthcentral.com /ency/408/003318.html (411 words)

	COLOBOMA
		What can a Parent Do A Coloboma is a congenital (present at birth) genetic defect that affects the iris of the eye.
		Sometimes a coloboma may be inherited from one of the parents and be part of a syndrome.
		Sometimes the coloboma is seen in the eye with a reduced eye size.
	www.capefearvalley.com /outreach/outreach/BabyBook/Pages/Coloboma.htm (585 words)

	Coloboma
		Associated conditions are: microphthalmia, polydactyly and mental retardation.
		Depending on the extent and location of the coloboma, there may be decreased visual acuity, nystagmus, strabismus, photophobia, and a loss of visual fields.
		IMPLICATIONS: Visual fields measurement is suggested when a coloboma of some-part of the inner eye is suspected (i.e., choroid or pigment epithelium).
	www.tsbvi.edu /Education/anomalies/coloboma.htm (101 words)

	COLOBOMA : Contact a Family - for families with disabled children: information on rare syndromes and disorders
		Coloboma means that there is a gap, or cleft, in one of the structures of the eye.
		Dominant mutations in PAX2 and PAX6 cause optic nerve Colobomas, in the MAF gene result in iris Coloboma and in the SHH gene cause Coloboma and Microphthalmia.
		Coloboma is one of the eye conditions covered by M.A.C.S. (Micro and Anophthalmic Children's Society).
	www.cafamily.org.uk /Direct/c51.html (647 words)

	Coloboma del iris
		Los colobomas del iris pueden aparecer como un orificio redondo y negro localizado dentro o al lado del iris (porciÃ³n coloreada del ojo).
		Un coloboma pequeÃ±o, especialmente si no estÃ¡ adherido a la pupila, puede hacer que una imagen secundaria se enfoque en la parte posterior del ojo ocasionando una imagen fantasma, visiÃ³n borrosa o disminuciÃ³n de la agudeza visual.
		El coloboma puede estar asociado con condiciones hereditarias, trauma del ojo o cirugÃa del ojo.
	www.umm.edu /esp_ency/article/003318.htm (409 words)

	Coloboma
		A coloboma is a gap in part of the structures of the eye.
		Coloboma of the iris may sometimes give the appearance of a keyhole in the pupil.
		If the hospital staff suspect a child has a coloboma, which is normally first noticed by the possible keyhole-like shape of the pupil, then they will carry out a full eye examination.
	www.rnib.org.uk /xpedio/groups/public/documents/PublicWebsite/public_rnib003643.hcsp (970 words)

	Coloboma definition - Medical Dictionary definitions of popular medical terms
		The resultant coloboma can be likened to a missing slice from a pie that may involve a number of different structures within the eye including the choroid, iris, lens, optic nerve, and retina.
		A coloboma can occur as an isolated defect in an otherwise normal baby, or it can be part of a multiple congenital malformation syndrome such as the cat-eye syndrome (named after the coloboma which gives the eye something of a feline look).
		Colobomas are also seen in the aniridia-Wilms tumor association (the concurrence of undergrowth of the iris of the eye and Wilms tumor of the kidney); and the trisomy 13 syndrome (a disastrous disease due to an extra chromosome number 13).
	www.medterms.com /script/main/art.asp?articlekey=12064 (191 words)

	eMedicine - Eyelid Coloboma : Article by Mounir Bashour
		Although an eyelid coloboma can occur in many locations, the most common position is at the junction of the medial and middle third of the upper lid.
		Of the 19 cases of upper eyelid coloboma, 5 occurred in isolation, 11 were associated with facial deformities, and 3 were part of a first arch syndrome (according to the Mustarde classification).
		The edges of the defect are freshened with sharp incisions, and precise anastomosis is preformed.
	www.emedicine.com /oph/topic673.htm (1398 words)

	Coloboma
		This is a picture of my daughter Carleigh's coloboma.
		seem to vary and not one coloboma family is the same as the other.
		Eye problems we have are coloboma, bilat., microphthalmia, ptosis, degen.
	groups.msn.com /Coloboma (248 words)

	Coloboma - Patient UK
		Coloboma - Patient UK PatientPlus articles are written for doctors and so the language can be technical.
		Coloboma of the iris This is the most commonly seen form, presenting as a keyhole-shaped notch in the inferonasal quadrant of the eye.
		Eyelid coloboma This is a full-thickness defect of the eyelid - the most common position is at the junction of the medial and middle third of the upper lid.
	www.patient.co.uk /showdoc/40001727 (405 words)

	MACS Homepage
		This is the home of information about Microphthalmia, Anophthalmia, Coloboma and related conditions.
		We offer support and information to parents and professionals in the UK and around
		Alternatively translate your information into English if you wish to contact us.
	www.macs.org.uk (303 words)

	Coloboma
		It is diagnosed by the presence of 4 out of seven of the problems below.
		Eighty percent of Charge syndrome patients present with colobomas of the retina, choroid or optic nerve.
		CHARGE Syndrome Foundation, Inc. 2004 Parkade Boulevard Columbia, MO 65202-3121
	www.lowvision.org /coloboma.htm (66 words)

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