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| | eMedicine - Atrioventricular Block, Third Degree, Congenital : Article by Robert Hamilton, MD (Site not responding. Last check: 2007-10-09) |
 | | Autoimmune congenital heart block is considered, but not definitively proven, to be the result of transplacental passage of maternal antibodies (ie, alloantibodies), which affect atriventricular conduction tissues. |
 | | Congenital heart block is presumed to be caused by injury from the placental passage of maternal anti-Ro (or related) antibodies, which are present in more than 90% of mothers if tested during pregnancy or at the time of delivery. |
 | | Children with isolated congenital complete heart block are most likely to have acquired the disease as a complication of subclinical or clinical maternal lupus erythematosus, maternal Sjögren syndrome, or another maternal autoimmune disease. |
| www.emedicine.com /ped/topic2496.htm (2760 words) |
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