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Topic: Coronary thrombosis


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  US FDA/CDRH: FDA Statement on Coronary Drug-Eluting Stents
Stent thrombosis in patients who receive DES is a primary area of interest for the agency because of the potential for serious adverse outcomes—even though stent thrombosis occurs at low rates.
The CYPHER Sirolimus-eluting Coronary Stent is indicated for improving coronary luminal diameter in patients with symptomatic ischemic disease due to discrete de novo lesions of length ≤ 30 mm in native coronary arteries with reference vessel diameter of ≥2.5 mm to ≤3.5 mm.
The TAXUS Express Paclitaxel-Eluting Coronary Stent System is indicated for improving luminal diameter for the treatment of de novo lesions ≤28 mm in length in native coronary arteries ≥2.5 to ≤3.75 mm in diameter.
www.fda.gov /cdrh/news/091406.html   (986 words)

  
 InfraReDx - new insight into Coronary Artery Disease
Such plaques, which cannot be detected by commonly-used tests such as a treadmill examination and even coronary angiography, are suspected to be the cause of most sudden cardiac deaths and non-fatal heart attacks.
Coronary artery disease is the leading cause of death in developed nations.
The cause of most heart attacks is rupture of a plaque in the coronary arteries followed by formation of a clot that blocks the flow of blood to heart muscle.
www.infraredx.com   (399 words)

  
 Coronary Artery Bypass Graft Surgery (Heart Bypass Surgery, CABG) Information on MedicineNet.com
According to the American Heart Association 427,000 coronary artery bypass graft (CABG) surgeries were performed in the United States in 2004, making it one of the most commonly performed major operations.
Coronary artery disease (CAD) occurs when atherosclerotic plaque (hardening of the arteries) builds up in the wall of the arteries that supply the heart.
When coronary arteries narrow more than 50 to 70%, the blood supply beyond the plaque becomes inadequate to meet the increased oxygen demand during exercise.
www.medicinenet.com /coronary_artery_bypass_graft/article.htm   (621 words)

  
 Cause of Coronary Heart Disease and symptoms of Coronary Heart Disease
The term coronary heart disease covers a group of clinical syndromes arising particularly from failure of the coronary arteries to supply sufficient blood to the heart.
They include angina pectoris, coronary thrombosis or heart attack, and sudden death without infarction.
A common symptom of heart disease is shortness of breath, which is caused by the blood being deprived of the proper amount of oxygen.
www.home-remedies-for-you.com /remedy/Coronary-Heart-Disease.html   (1423 words)

  
  Heart Disease - Coronary Thrombosis
This is a blood clot occurring in the arteries of the heart and occluding it (coronary occlusion).
A blood clot in a blood vessel is a "thrombus." When it becomes detached from vessel walls and floats in the blood it is called an "embolus." The resultant condition is known as "thrombosis." Thrombi may lodge in a heart artery (coronary artery), plug it, and block blood supply to a wedge-shaped heart muscle section.
The patient is prostrated and falls to the ground with ashen-faced pallor; pain in the heart region is severe, constricting and lancinating; pulse is thready—rapid, irregular and feeble; breathing becomes shallow and rapid; he has clammy, cold perspiration.
www.rawfoodexplained.com /diseases-relating-to-the-heart/coronary-thrombosis.html   (1322 words)

  
  InfoMedics Malaysia
Later evidence indicated, however, that, though thrombotic occlusion of an atheromatous lesion in a coronary artery is the most common cause of the disorder, the manifestations are the result of the death of an area of heart muscle (infarction).
Coronary thrombosis is present in a majority of the hearts examined at autopsy and undoubtedly plays an important role.
Coronary artery bypass surgery is widely used to restore adequate blood flow to the heart muscle beyond severe atheromatous obstruction in the main coronary arteries.
www.angelfire.com /md/LeeHH/heart1.html   (2614 words)

  
 coronary - Search Results - MSN Encarta
When thrombosis occurs in an artery, the tissues that the artery normally supplies with blood suffer infarction—that is, they die from a lack of...
The heart is nourished not by the blood passing through its chambers but by a specialized network of blood vessels.
Coronary Heart Disease, chronic illness in which the coronary arteries, the vessels that supply oxygen-carrying blood to the heart, become narrowed...
ca.encarta.msn.com /coronary.html   (141 words)

  
 Coronary thrombosis (heart attack)
This is known as a coronary thrombosis, a myocardial infarction or heart attack.
Conversely, plaque rupture leading to a coronary thrombosis often occurs in someone with no previous history of angina.
An alternative is emergency dilatation (enlarging) of the occluded coronary artery using a balloon, a procedure known as coronary angioplasty.
www.netdoctor.co.uk /diseases/facts/coronarythrombosis.htm   (1846 words)

  
 Thrombosis - Wikipedia, the free encyclopedia
Thrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system.
The formation of a thrombus is usually caused by an injury to the vessel's wall, either by trauma or infection, and by the slowing or stagnation of blood flow past the point of injury.
If a bacterial infection is present at the site of thrombosis, the thrombus may break down, spreading particles of infected material throughout the circulatory system (pyemia, septic embolus) and setting up metastatic abscesses wherever they come to rest.
en.wikipedia.org /wiki/Coronary_thrombosis   (265 words)

  
 Book "Myogenic Theory of the Myocardial Infarction"
The isolated coronary lesions are responsible for the pathological disharmony in the ventriculogram, resulting from the effects of ischemia and loss of regional contractility, in addition to them the mechanical effect of the hemodynamic overload caused by the exaltation of the other non-ischemic ventricular segments during the phase of ventricular ejection.
In combined lesions of 2 or 3 coronary arteries, the repercussions on the ventriculogram are responsible for the pathological harmony which may lead to infarction of the most injured segment, or else to cardiac insufficiency.
The net of coronary collateral circulation is not always able to prevent myocardial infarction, because it develops depending on the anatomical features of the obstructive process, and is not always sufficient to face the demands of the physical activity of the coronary patient.
www.infarctcombat.org /LivroTM/parte8.htm   (1908 words)

  
 Current concepts in antiplatelet therapy for cardiovascular disease
Thrombosis as a factor in the pathogenesis of coronary atherosclerosis.
The pathogenesis of coronary artery disease and acute coronary syndromes (1).
The pathogenesis of coronary artery disease and acute coronary syndromes (2).
www.jaapa.com /issues/j20040301/articles/antiplatelet.html   (4443 words)

  
 Thrombosis/Coronary Thrombosis
Coronary thrombosis is a term used to describe the blockage of a coronary artery secondary to blood clotting within the artery.
Thrombosis of coronary arteries occurs when the opening, or lumen, of the artery becomes so small that the blood flow through the narrowed segment slows, allowing the blood to clot in the artery.
Thrombosis of a coronary artery can lead to a heart attack if not treated.
www.surgery.usc.edu /divisions/ct/zglossary-thrombosis.html   (98 words)

  
 eMedicine - Coronary Artery Atherosclerosis : Article by Vibhuti N Singh, MD, MPH, FACC, FSCAI
Coronary artery atherosclerosis or CAD refers to the presence of atherosclerotic changes within the walls of the coronary arteries, which causes impairment or obstruction of normal blood flow with resultant myocardial ischemia.
Coronary angiography: Coronary arterial luminography remains the criterion standard for defining significant flow-limiting stenoses that must be revascularized through percutaneous or surgical intervention to improve prognosis.
This usually occurs in diabetic patients, in whom coronary arteries are traditionally described as small-caliber vessels, when that appearance is actually due to the presence of diffuse symmetrical involvement of the entire vessel, as elucidated by recent IVUS studies.
www.emedicine.com /med/topic446.htm   (12553 words)

  
 Thrombosis
Thrombosis is clearly the most common cause of death in the United States.
The causes of hypercoagulability and overt thrombosis are becoming more clear and often definitive with enhanced knowledge of hemostasis and the development and extended utilization of testing systems useful for evaluating patients with thrombotic and thromboembolic disorders.
Thrombosis, be it arterial or venous, can no longer be viewed as a general diagnosis; approaching thrombosis in this manner probably accounts for not only many treatment failures, but also for often confusing and conflicting results of clinical trials.
www.thrombosis.net /introduction/introcontent.htm   (508 words)

  
 Coronary Thrombosis Related to Use of Xenadrine[reg] RFA   (Site not responding. Last check: )
Persistent occlusion of the apical portion of the anterior descending artery was attributed to embolization of the proximal thrombus despite AngioJet thrombectomy, distal angioplasty, and intracoronary infusion of both nitroglycerin and adenosine.
The myocardial infarction was likely caused by in situ coronary thrombosis, perhaps related to transient coronary spasm and transient platelet activation as a result of intense sympathetic activity.
Coronary vasospasm is thought to be the underlying mechanism of myocardial infarction in patients taking ma huang.
www.arabmedmag.com /issue-15-10-2005/casereport/main01.htm   (2063 words)

  
 Thrombophilia in coronary artery disease: A double jeopardy Indian Journal of Medical Research - Find Articles
The clinical manifestations of the chronic development of coronary artery atheroma are angina and acute myocardial infarction.
But, since the onset of thrombosis in majority of cases is at a later stage, it is unlikely that genetic causes may be the sole determinant.
The underlying processes that lead to atheroma formation and coronary thrombosis are complex involving various systems that regulate vasoactivity, adhesion molecules, inflammation, lipid metabolism, coagulation and the fibrinolytic pathways2.
www.findarticles.com /p/articles/mi_qa3867/is_200407/ai_n9446062   (821 words)

  
 TIME.com: CORONARY THROMBOSIS -- Oct. 3, 1955 -- Page 1
The clot is a thrombus, the process of its formation is thrombosis, and if it happens in one of the coronary arteries, it is coronary thrombosis (while there are medical distinctions in their precise use, the terms "coronary occlusion" and "cardiac infarction" are generally synonymous with "coronary thrombosis").
A mild coronary thrombosis could be one in which a relatively small coronary artery has been closed and a small heart area has suffered damage.
The symptoms of coronary thrombosis vary greatly from patient to patient, but nearly always include a cramping pain in the chest that is sometimes very similar to the "gas pains" of indigestion.
www.time.com /time/magazine/article/0,9171,807676,00.html   (651 words)

  
 Coronary Thrombosis Trust
Rupture of a plaque sets off the acute coronary thrombosis that causes heart attack (myocardial infarction) and unstable angina.
Inflammation of the endothelium, the lining cells of the inside of the arteries, is also caused by raised homocysteine levels.
We still favour the theory put forward in 1885 by von Rokitanski, which says that thrombosis is the common factor in the way this disease develops.
www.coronarythrombosistrust.org.uk /html/qa-atherosclerosis.html   (259 words)

  
 Coronary Thrombosis Prevention - References
(252) Monica project has found little correlation between coronary heart disease mortality and mean level of cholesterol, systolic blood pressure and proportion of smokers.
Coronary heart disease risk reduced by 20-30% with 10% reduction in serum cholesterol, by 10-15% with a 5-6 mm reduction in diastolic blood pressureBP and by 50-70% with smoking cessation.
(279) Cholesterol screening in young adults should be limited to those with coronary heart disease or other unusual factors which place them at high short term risk of death from coronary heart disease.
www.takeheart.co.uk /qcoms6.htm   (2143 words)

  
 Glycoprotein IIIa PlA Polymorphism Associates With Progression of Coronary Artery Disease and With Myocardial ...
of the Pl polymorphism of the gene for GPIIIa with coronary thrombosis
The pathogenesis of coronary artery disease and the acute coronary syndromes.
Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischemic death.
atvb.ahajournals.org /cgi/content/full/19/10/2573   (3991 words)

  
 About thrombosis   (Site not responding. Last check: )
When a clot is formed inside a blood vessel, blocking the whole of a vein or artery, this is known as thrombosis.
A blood clot in an artery of the heart, such as the coronary artery is known as a heart attack, or myocardial infarction
An example of this is when part of the clot from a deep vein thrombosis breaks off, goes up the leg, through the right side of the heart and lodges in a lung artery (pulmonary artery).
www.thrombosis-charity.org.uk /aboutthrom.htm   (396 words)

  
 Subacute coronary stent thrombosis in a patient developing clopidogrel associated thrombotic thrombocytopenic purpura ...
Subacute coronary stent thrombosis in a patient developing clopidogrel associated thrombotic thrombocytopenic purpura -- von Mach et al.
Subacute coronary stent thrombosis in a patient developing clopidogrel associated thrombotic thrombocytopenic purpura
It is commonly used for the prevention of thrombosis
heart.bmjjournals.com /cgi/content/full/91/2/e14   (956 words)

  
 Molecular Imaging Identifies Regions with Microthromboemboli During Primary Angioplasty in Acute Coronary Thrombosis -- ...
We hypothesized that myocardial MTE in acute coronary
On coronary angiography, an occlusive thrombus was observed
Myocardial perfusion imaging in the setting of coronary artery stenosis and acute myocardial infarction using venous injection of FS-069, a second generation echocardiographic contrast agent.
jnm.snmjournals.org /cgi/content/full/45/7/1194   (3325 words)

  
 THROMBOSIS
Thrombosis is clearly the most common cause of death in the United States (see Table 1).
These and common clinical defects leading to thrombosis are discussed later and found in Table 2.
MISSION: Specializing in all clinical aspects of the diagnosis of causes and specific treatment of Thrombosis, including deep vein thrombosis, pulmonary embolus, recurrent miscarriage (placental thrombosis), transient cerebral ischemia (TIA), and stroke (cerebrovascular thrombosis) retinal vascular thrombosis and coronary artery thrombosis.
www.strategytech.com   (278 words)

  
 Cardiovascular Pathology Index
Heart and LAD coronary artery with recent thrombus, gross
Coronary artery with recent thrombus, longitudinal section, gross
Coronary artery with recent thrombus, cross section, gross
www-medlib.med.utah.edu /WebPath/CVHTML/CVIDX.html   (173 words)

  
 MedlinePlus: Coronary Disease
Coronary Artery Disease (National Heart, Lung, and Blood Institute)
Coronary Artery Disease (Mayo Foundation for Medical Education and Research)
The primary NIH organization for research on Coronary Disease is the National Heart, Lung, and Blood Institute
www.nlm.nih.gov /medlineplus/coronarydisease.html   (437 words)

  
 Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitor -- Zoldhelyi et al. ...
Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitor -- Zoldhelyi et al.
selectin inhibition of coronary thrombosis is underscored by the
Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury.
ajpheart.physiology.org /cgi/content/full/279/6/H3065   (7021 words)

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