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	Coronavirus - Wikipedia, the free encyclopedia
		Coronavirus is a genus of animal virus belonging to the family Coronaviridae.
		The name "coronavirus" draws reference to the "corona" -- the "ring-like radiating structure" formed by the outermost part of the atmosphere of the sun.
		Feline enteric coronavirus is a pathogen of minor clinical significance, but spontaneous mutation of this virus can result in feline infectious peritonitis (FIP), a disease associated with high mortality.
	en.wikipedia.org /wiki/Coronavirus (690 words)

	Coronavirus -- Facts, Info, and Encyclopedia article (Site not responding. Last check: 2007-10-21)
		Coronavirus is a genus of animal ((virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein) virus belonging to the family (Click link for more info and facts about Coronaviridae) Coronaviridae.
		The naming of this fourth coronavirus is still a controversial issue, as the three labs are still battling over who actually discovered the virus first and hence earns the right to name the virus.
		Early 2005, a research team at the University of Hong Kong reported finding a fifth human coronavirus in two (Respiratory disease characterized by inflammation of the lung parenchyma (excluding the bronchi) with congestion caused by viruses or bacteria or irritants) pneumonia patients, and subsequently named it HKU1.
	www.absoluteastronomy.com /encyclopedia/c/co/coronavirus.htm (624 words)

	Coronavirus infection aka corona virus affects many dogs
		Different members of the coronavirus family have a predilection for specific species; thus, a coronavirus infection in the dog is highly unlikely to be contagious to a person or other animal.
		Because the coronavirus is highly contagious, animals that live in kennels or participate in dog shows are at a high risk for contracting it and should be vaccinated.
		Canine coronavirus is passed on when a susceptible dog or puppy ingests feces from a dog that has the virus.
	www.workingdogs.com /vccorona.htm (717 words)

	CDC Media Relations - Telebriefing Transcript - March 24, 2003
		Coronavirus is not a Paramyxovirus, it is not a Metapneumovirus.
		This, in scientific terms, is very strong evidence supporting Coronavirus as an etiology, but we know from sequencing pieces of the virus DNA that it is not identical to the Coronaviruses that we've seen in the past.
		Since the Coronavirus has not, as it seems, been known to be deadly before in humans, could you give us any information on what is different about this virus, maybe the origins of it, you know, anything you can tell us on that.
	www.cdc.gov /od/oc/media/transcripts/t030324.htm (5111 words)

	Medmicro Chapter 60
		On rare occasions, gastrointestinal coronavirus infection has been associated with outbreaks of diarrhoea in children, but these enteric viruses are not well characterized and are not discussed in this chapter.
		Coronavirus virions are spherical to pleomorphic enveloped particles (Fig.
		Because coronavirus infections are common, many individuals have specific antibodies in their nasal secretions, and these antibodies can protect against infection.
	gsbs.utmb.edu /microbook/ch060.htm (1262 words)

	Balgownie Veterinary Hospital: Coronavirus
		Coronavirus (CCV) is a virus closely related to Parvovirus.
		Coronavirus can be picked up by dogs sniffing long grass where infected dogs have gone to the toilet up to one year ago.
		Coronavirus causes severe bloody watery diarrhoea, shock, abdominal pain and vomiting.
	www.balgownievet.com.au /1_dog_coronavirus.htm (407 words)

	Coronaviruses
		Coronavirus particles are irregularly-shaped, ~60-220nm in diameter, with an outer envelope bearing distinctive, 'club-shaped' peplomers (~20nm long x 10nm at wide distal end).
		The number of coronavirus serotypes and the extent of antigenic variation is unknown.
		Amplification of short regions of the polymerase gene, (the most strongly conserved part of the coronavirus genome) by reverse transcriptase polymerase chain reaction (RT-PCR) and nucleotide sequencing revealed that the SARS virus is a novel coronavirus which has not previously been present in human populations.
	www-micro.msb.le.ac.uk /3035/Coronaviruses.html (1937 words)

	CIDRAP >> New coronavirus may be SARS cause, CDC says
		CDC experts have grown the coronavirus in cultures of tissue samples from SARS patients and have viewed the virus in electron microscope studies, Gerberding said.
		Gerberding added, "This is not identical to the coronaviruses we've seen in the past, so this may be a new or emerging coronavirus infection." She explained that there are three groups of coronaviruses, but the genetic sequencing studies done so far indicate that this particular coronavirus does not fall precisely into any of them.
		Further steps needed to confirm the coronavirus hypothesis include further culturing of the virus from appropriate specimens, sequencing of the viral genome, and examining specimens from patients at different stages of the illness, the CDC news release stated.
	www.cidrap.umn.edu /cidrap/content/hot/sars/news/coronavirus.html (854 words)

	Coronavirus Confirmed as Cause of SARS
		But the virus identified as the cause of SARS appears to be a previously unknown member of the coronavirus family.
		Although researchers had widely accepted this new coronavirus as the primary cause of SARS in recent weeks, a series of conditions known as Koch's postulates had to be met before it could be officially recognized as the cause.
		Those conditions include: finding the virus in all cases of the disease, isolating the virus and culturing it in the lab from an infected tissue sample, reproducing the disease in a previously healthy host, and identifying the virus in the infected host.
	www.webmd.com /content/article/63/72113.htm?z=1728_00000_1000_ln_03 (444 words)

	Coronavirus SARS Picture: Virus Life Cycle image: Viral Replication graphic, Russell Kightley Media (Site not responding. Last check: 2007-10-21)
		The viruses collect in membrane bound sacs and are eventually released onto the surface of the cell in large numbers.
		It then enters the cell by membrane fusion with the plasma membrane or by receptor mediated endocytosis (a clathrin coated vesicle is seen floating in the region).
		The nucleus is shown in the lower right hand corner of the image and the N protein presumably enters through the nuclear pores (the flower-like structures decorating the surface of the nucleus).
	www.rkm.com.au /VIRUS/CORONAVIRUS/coronavirus-replication.html (729 words)

	Exclusive - House Flies Can Spread Coronavirus
		Avian Dis 2003 Jan-Mar;47(1):149-53 Mechanical transmission of turkey coronavirus by domestic houseflies (Musca domestica Linnaeaus).
		So, Jeff, it is my reasonable guess that SARS coronavirus can be spread by house flies for between 3 and 72 hours after a fly has come into contact with SARS coronavirus as is likely to happen if a fly lands on any infected human waste/body fluids.
		You will note that, for turkey coronavirus, it is sufficient to have one single infected fly land on a bird and the bird can become infected.
	www.rense.com /general37/exclu.htm (655 words)

	Rapid identification of coronavirus replicase inhibitors using a selectable replicon RNA -- Hertzig et al. 85 (6): 1717 ...
		assay for the identification of coronavirus replicase inhibitors.
		Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
		Coronavirus as a possible cause of severe acute respiratory syndrome.
	vir.sgmjournals.org /cgi/content/full/85/6/1717 (4878 words)

	Another New Coronavirus Found In Japan
		The new coronavirus has been designated HCoV-NL63 and is clearly different from the 3 known human coronavirus species: _Human coronavirus 229E_, _Humman coronavirus OC43_, and the _SARS coronavirus_.
		The precise evolutionary relationship of this new human coronavirus to the established members of the family has yet to be determined.
		Now a paper entitled "Detection of human coronavirus NL63 from children with respiratory illness in 2003 - Sendai City" has appeared on the Japanese National Institute of Infectious Diseases web-site entitled "Detection of human coronavirus NL63 from children with respiratory illness in 2003 - Sendai City".
	www.rense.com /general54/corona.htm (508 words)

	WHO \| Summary on major findings in relation to coronavirus by members of the WHO multi-centre collaborative network on ...
		A new coronavirus which is unlike any other known members of the genus Coronavirus has been isolated consistently by several network laboratories from SARS patients from several countries.
		Generic coronavirus primers detect a new coronavirus RNA in cell-culture and in specimens from SARS patients.
		Partial sequencing of a new coronavirus in several laboratories confirms affiliation of a new coronavirus to the genus Coronavirus as well as dissimilarities with known members belonging to each of the three existing groups of this genus.
	www.who.int /csr/sars/findings/en (346 words)

	Detection of Coronavirus in the Central Nervous System of a Child With Acute Disseminated Encephalomyelitis -- Yeh et ...
		Coronavirus OC43 was detected in the CSF and nasopharyngeal
		Detection of rhinovirus, respiratory syncytial virus, and coronavirus infections in acute otitis media by reverse transcriptase polymerase chain reaction.
		Coronavirus in brain tissue from patients with multiple sclerosis.
	pediatrics.aappublications.org /cgi/content/full/113/1/e73?... (2179 words)

	CANINE CORONAVIRUS
		Canine Coronavirus is a virus that affects the intestinal tract of dogs.
		The clinical signs of Canine Coronavirus vary from mild and undetectable to severe and fatal.
		Dogs that have recovered from Coronavirus develop some immunity, but the duration of immunity is unknown.
	www.cpvh.com /Articles/8.html (364 words)

	SARS/Coronavirus Suspected (Site not responding. Last check: 2007-10-21)
		Coronaviruses are a common cause of mild to moderate upper-respiratory illness in humans and are associated with respiratory, gastrointestinal, liver, and neurologic disease in several animal species.
		The new coronavirus was isolated from clinical specimens of two patients with SARS, cultured in Vero E6 cells, and then characterized by several laboratory methods.
		Other serologic tests demonstrated that the new agent reacts with antisera to one of the three known coronavirus serogroups, but sequence analysis suggests that it is distinct from the known coronaviruses.
	www.hivdent.org /cdc/cdcnSCS042003.htm (370 words)

	WHO \| Coronavirus never before seen in humans is the cause of SARS
		The speed at which this virus was identified is the result of the close international collaboration of 13 laboratories from 10 countries.
		Over the past three weeks, due to the urgency surrounding the worldwide threat to health of SARS and early indications this was a new member of the coronavirus family, research has proceeded under the assumption that SARS was caused by a new coronavirus.
		Credit for the coronavirus findings, which definitively pinpoints the cause of SARS, is attributed to the 13 laboratories, working in conjunction with WHO.
	www.who.int /mediacentre/releases/2003/pr31/en (584 words)

	Reverse Genetics System for the Avian Coronavirus Infectious Bronchitis Virus -- Casais et al. 75 (24): 12359 -- The ...
		The 5' two-thirds of a coronavirus genome encompass the replicase gene.
		cDNAs from the genomic RNA of porcine coronavirus transmissible
		Coronavirus IBV: partial amino terminal sequencing of spike polypeptide S2 identifies the sequence Arg-Arg-Phe-Arg-Arg at the cleavage site of the spike precursor propolypeptide of IBV strains Beaudette and M41.
	jvi.asm.org /cgi/content/full/75/24/12359 (7074 words)

	Rad's Coronavirus Page (Site not responding. Last check: 2007-10-21)
		In addition to discussing basic viral features, the focus of the page is on the most common clinical manifestation of Human Coronavirus infection, the Common Cold.
		Coronavirus was first isolated from chickens in 1937 by Beaudette and Hudson.
		When the the family was distinguished on the basis of its distinctive morphology, it received separate classification and the name corona because of the crownlike appearance of the surface projections.
	www.stanford.edu /group/virus/corona/virushome.html (256 words)

	C - Coronavirus
		Coronavirus may cause viral diarrhea and may make fatality from parvovirus more likely if the infections occur concurrently.
		On the other hand, this virus causes minimal damage to the intestines and may not cause clinical illness on its own.
		Personally, I do not recommend the use of coronavirus vaccine.
	www.vetinfo.com /dencyclopedia/decoronav.html (169 words)

	December '96 - Coronavirus (Site not responding. Last check: 2007-10-21)
		This month, I’ll describe canine coronavirus, which is probably the second most important cause of virus-infected intestinal disease (viral enteritis) in dogs.
		In contrast to parvovirus, coronavirus is easily killed by most chemical d is infectants.
		Dual infection with parvovirus and coronavirus at the same time have been shown to be more severe than either virus alone.
	www.espomagazine.com /vet/dec96.htm (580 words)

	SARS coronavirus: a new challenge for prevention and therapy -- Holmes 111 (11): 1605 -- Journal of Clinical ...
		Phylogenetic analysis of coronaviruses, based on the polymerase gene, shows that SARS coronavirus is different from each of the three groups of the previously known coronaviruses.
		The spike glycoprotein S is a good candidate for vaccines because neutralizing antibodies are directed against S. Blockade of the specific virus receptor on the surface of the host cell by monoclonal antibodies or other ligands can prevent virus entry.
		The putative helicase of the coronavirus mouse hepatitis virus is processed from the replicase gene polyprotein and localizes in complexes that are active in viral RNA synthesis.
	www.jci.org /cgi/content/full/111/11/1605 (3517 words)

	Coronavirus Virion (CoV), image by Russell Kightley Media (Site not responding. Last check: 2007-10-21)
		SARS is caused by a novel coronavirus (original image is 3210 pixels across).
		CORONAVIRUSES AND SARS (Severe Acute Respiratory Syndrome): A new type of coronavirus has been identified as the cause of the emergent disease called Severe Acute Respiratory Syndrome or SARS.
		The Transmissible Gastroenteritis Coronavirus Contains a Spherical Core Shell Consisting of M and N Proteins.
	www.rkm.com.au /VIRUS/CORONAVIRUS/coronavirus-virion.html (560 words)

	CDC \| SARS-Associated Coronavirus (SARS-CoV) Sequencing
		On April 14, 2003, the Centers for Disease Control and Prevention (CDC) announced the completion of the full-length genetic sequencing of the genome of the SARS-associated coronavirus (SARS-CoV).
		The sequence data confirmed that SARS-CoV is a previously unrecognized coronavirus.
		The accession number for the sequence of SARS-CoV (Urbani strain) is AY278741.
	www.cdc.gov /ncidod/sars/sequence.htm (219 words)

	New virus linked to childhood diseases - Children's Health - MSNBC.com (Site not responding. Last check: 2007-10-21)
		The new virus is a coronavirus, a family of viruses that cause common colds, animal diseases and severe acute respiratory syndrome, a new disease that emerged in China in 2003, killing 800 people globally and causing a worldwide panic before it was contained.
		And 11 babies infected with the new coronavirus were newborns in intensive care units.
		Kawasaki disease can be marked by an eye infection, redness of the mouth or throat, rash, redness or swelling of the hands or feet, and swollen lymph nodes.
	www.msnbc.msn.com /id/6844203 (415 words)

	New Scientist Breaking News - Identity of killer pneumonia bug confirmed (Site not responding. Last check: 2007-10-21)
		Scientists have satisfied key tests that confirm that the virus causing the global outbreak of severe pneumonia is a new type of coronavirus.
		To be definitively declared the cause of SARS, the novel virus must satisfy three conditions known as Koch's postulates.
		First, the suspect microbe must be isolated from all, or nearly all, cases; second, it must be cultured in isolation; and third, those cultured germs must be able to re-create the disease in a test animal.
	www.newscientist.com /article.ns?id=dn3582 (572 words)

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