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Topic: Corticosterone


In the News (Thu 24 Dec 09)

  
  corticosterone on Encyclopedia.com   (Site not responding. Last check: 2007-10-08)
Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol and cortisone.
Corticosterone regulation of insulin-like growth factor I, IGF-binding proteins, and growth in streptozotocin-induced diabetic rats.
Increased serum corticosterone and glucose in offspring of chromium(III)-treated male mice.
www.encyclopedia.com /html/c1/corticostrne.asp   (558 words)

  
 Corticosterone - Wikipedia, the free encyclopedia
Corticosterone is a 21 carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
In many species corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
However, in humans, corticosterone is produced primarily in the zona glomerulosa of the adrenal cortex.
en.wikipedia.org /wiki/Corticosterone   (104 words)

  
 Corticosterone Supplementation Reduced Selective Protein Kinase C Isoform Expression in the Epidermis of ...
corticosterone with 5, 10, and 35 mg of corticosterone implants
Elevation of plasma corticosterone in adrenalectomized mice with corticosterone implants.
of corticosterone to adrenalectomized mice by an implanted pellet
cebp.aacrjournals.org /cgi/content/full/10/6/679   (5040 words)

  
 Stress, Corticosterone and Testosterone in Male Desert Tortoises
The elevated corticosterone is believed to inhibit the secretion of gonadotropin and thus shut down gonadal secretion of steroids.
Corticosterone does increase as in other reptiles, but no decrease in testosterone is seen until about 24 hours after the onset of stress when corticosterone has also returned to pre-stress levels.
The reason for this linkage of corticosterone and testosterone secretion is not known, but the close anatomical relationship of the two tissues may play a role.
www.deserttortoise.org /abstract/abstracts2001/2001abs22.html   (231 words)

  
 Corticosterone Facilitates the Acquisition of Cocaine Self-Administration in Rats: Opposite Effects of the Type II ...
Corticosterone was measured 15 min after the self-administration of single infusions of cocaine or saline.
in the plasma corticosterone responses to 20 mg/kg cocaine.
Donald RA (1966) Dexamethasone suppression of the plasma corticosterone response.
jpet.aspetjournals.org /cgi/content/full/287/1/72?ma+href=   (6469 words)

  
 Ontogeny of Corticosterone-Inducible Growth Hormone-Secreting Cells during Chick Embryonic Development -- Bossis and ...
Corticosterone (0, 0.02, 0.2, and 2 µg in 300 µl of saline) was injected into separate eggs on e9, e10, e11, and e12.
Corticosterone (0, 0.02, 0.2, 2, and 20 µg in 300 µl of saline) was injected into separate eggs on e0, e8, e9, e10, e11, and e12.
Eggs were injected either with 2 µg of corticosterone in saline or saline alone on e11, and the number of GH secreting-cells was estimated on e13, e16, e19, and d1 (day of hatch) using reverse hemolytic plaque assays.
endo.endojournals.org /cgi/content/full/141/7/2683   (5672 words)

  
 Journal of Carcinogenesis | Full text | Glucocorticoid-like effects of antihepatocarcinogen Rotenone are mediated ...
In this study, exposure of mice to exogenous corticosterone significantly reduced thymus/body weight ratios; this effect was mimicked by rotenone (Fig 1).
Surprisingly, a 3-fold increase in serum levels of corticosterone was observed in rotenone-treated mice (Fig 6).
Based on the well-known inhibitory effects of glucocorticoids on cell growth and DNA synthesis [8], our data suggest that enhancing corticosterone secretion by rotenone is likely to, at least in part, mediate the anti-hepatocarcinogenic effect known to occur in response to this compound [3].
www.carcinogenesis.com /content/2/1/2   (3183 words)

  
 Role of Corticosterone in the Enhancement of the Antibody Response after Acute Cocaine Administration -- Stanulis et ...
primarily in an increase in plasma corticosterone and a release
cortex to release corticosterone (Rivier and Vale, 1987
Sarnyai, Z., Biro, E., Penke, B. and Telegdy, G.: The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats.
jpet.aspetjournals.org /cgi/content/full/280/1/284   (4760 words)

  
 Effects of corticosterone on muscle mitochondria identifying different sensitivity to glucocorticoids in Lewis and ...
Plasma corticosterone, COX, and SDH activities and COX/SDH ratio in sham, ADX + 0 mg, ADX + 12 mg, ADX + 50 mg ADX + 100 mg, and ADX + 200 mg Lewis and Fischer rats
the Lewis strain, 50-, 100-, and 200-mg corticosterone pellet
Corticosterone, brain mineralocorticoid receptors (MRs) and the activity of the hypothalamic-pituitary-adrenal (HPA) axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA axis.
ajpendo.physiology.org /cgi/content/full/286/2/E159   (5413 words)

  
 The Purpose of Cortisol and Corticosterone
Cortisol is for intestinal disease (diarrhea) and corticosterone serum disease.
Base corticosterone is increased in plasma from dehydration, but the much higher corticosterone from immobilization stress is not affected by water status.
Reinforcing the concept that cortisol is relied on more for intestinal disease control and corticosterone for serum disease is the circumstance that corticosterone at physiological levels shows a marked inhibition of insulin and enhancement of glucagon in vitro.
members.tripod.com /~charles_W/cortisol.html   (8014 words)

  
 Circadian Variation in Basal Plasma Corticosterone and Adrenocorticotropin in the Rat: Sexual Dimorphism and Changes ...
Corticosterone was measured in unextracted, thermally denatured plasma
Mesor concentrations of plasma I-ACTH and corticosterone in male rats and in females at estrus, postestrus, diestrus, and proestrus.
Regression of plasma corticosterone on plasma I-ACTH in male rats and in females at estrus and proestrus.
endo.endojournals.org /cgi/content/full/138/9/3842   (5041 words)

  
 Corticosterone Acts Directly at the Amygdala to Alter Spinal Neuronal Activity in Response to Colorectal Distension -- ...
Lee Y, Schulkin J, and Davis M. Effect of corticosterone on the enhancement of the acoustic startle reflex by corticotropin releasing factor (CRF).
Makino S, Gold PW, and Schulkin J. Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus.
Makino S, Gold PW, and Schulkin J. Effects of corticosterone on CRH mRNA and content in the bed nucleus of stria terminalis; comparison with the effects in the central nucleus of the amygdala and the paraventricular nucleus of the hypothalamus.
jn.physiology.org /cgi/content/full/89/3/1343   (5028 words)

  
 Poultry Science: Physiological effects of elevated plasma corticosterone concentrations in broiler chickens. An ...   (Site not responding. Last check: 2007-10-08)
The simple performance, and the close relation between circulating corticosterone levels and heterophil counts, makes this an easy and quick method that is sensitive to increased levels of circulating corticosterone from base levels.
The changed responsiveness of the adrenal glands to adrenocorticotropic hormone after increased circulating corticosterone levels may be an indication of the coping strategies during stress.
Tonic immobility and heterophil/lymphocyte responses of the domestic fowl to corticosterone infusion.
www.findarticles.com /p/articles/mi_qa4109/is_200308/ai_n9244274   (1190 words)

  
 Relationships between Environmental Organochlorine Contaminant Residues, Plasma Corticosterone Concentrations, and ...   (Site not responding. Last check: 2007-10-08)
The observation of reduced basal plasma corticosterone concentrations in herring gull embryos exposed to high environmental concentrations of organochlorines is in contrast to recently published observations in amphibians.
Similar to fish and amphibians, measurement of plasma corticosterone is the most common technique used to assess the functional status of the HPA axis and/or adrenal gland in wild and domestic birds (36-40).
Influence of corticosterone on the metabolism of palmitate and glucose in cockerels.
ehp.niehs.nih.gov /members/1999/107p179-186lorenzen/lorenzen-full.html   (6091 words)

  
 Corticosterone-dependent driving influence of the suprachiasmatic nucleus on adrenal sensitivity to ACTH -- Sage et al. ...
Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release.
Decrease of endogenous vasopressin release necessary for expression of the circadian rise in plasma corticosterone: a reverse microdialysis study.
Szafarczyk, A, Ixart G, Malaval F, Nouguier-Soulé J, and Assenmacher I. Effects of lesions of the suprachiasmatic nuclei and of p-chlorophenylalanine on the circadian rhythms of adrenocorticotrophic hormone and corticosterone in the plasma, and on locomotor activity of rats.
ajpendo.physiology.org /cgi/content/full/282/2/E458   (5284 words)

  
 Defective ACTH response to stress in previously stressed rats: dependence on glucocorticoid status -- Martí et ...
Stress-induced inhibition of plasma corticosterone response to subsequent stress in rats: a nonadrenocorticotropin-mediated mechanism.
Stress down-regulates corticosterone receptors in a site-specific manner in the brain.
Corticosterone can facilitate as well as inhibit corticotropin-releasing hormone gene expression in the rat hypothalamic paraventricular nucleus.
ajpregu.physiology.org /cgi/content/full/277/3/R869   (5532 words)

  
 Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically ...
Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice -- Harper et al.
Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice
Fecal levels of corticosterone at 17 mo of age were influenced
physiolgenomics.physiology.org /cgi/content/abstract/15/1/44   (412 words)

  
 Attenuated neuroendocrine responses to emotional and physical stressors in pregnant rats involve adenohypophysial ...
Either 0·2 ml (for detection of ACTH and corticosterone) or 0·6 ml (for ACTH, corticosterone, oxytocin and vasopressin, and lactate as an indicator of muscle activity) blood samples, replaced immediately by sterile 0·9 % saline, were taken under basal conditions at 09.30 and 10.00 h and after the respective stress exposure.
Plasma ACTH and corticosterone concentrations from virgin and pregnant, and virgin and lactating rats, respectively, were estimated in different assays.
Plasma ACTH (A) and corticosterone (B) concentrations in virgin rats and between days 9 and 12 of lactation under basal conditions and in response to exposure to the elevated plus-maze (EPM) followed by forced swimming (FS) according to the protocol described in the legend to Fig.
jp.physoc.org /cgi/content/full/508/1/289   (8466 words)

  
 Plasma corticosterone response to acute and chronic voluntary exercise in female house mice -- Girard and Garland 92 ...
Plasma corticosterone response to acute and chronic voluntary exercise in female house mice
Blood samples for corticosterone determination were collected at six times over 52 days with 7-14 days between sampling.
Corticosterone, body condition and locomotor activity: a model for dispersal in screech-owls.
jap.physiology.org /cgi/content/full/92/4/1553   (6110 words)

  
 Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS -- ...
Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS -- Lenczowski et al.
Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS
Different responses of plasma ACTH and corticosterone and of plasma interleukin-1-beta to single and recurrent endotoxin challenges.
ajpregu.physiology.org /cgi/content/full/273/6/R1870   (4206 words)

  
 Glucocorticoids act in the dorsal hindbrain to increase arterial pressure -- Scheuer et al. 286 (1): 458 -- AJP - Heart ...
corticosterone (Cort) or the GR antagonist mifepristone (Mif)
Corticosterone exerts site-specific and state-dependent effects in prefrontal cortex and amygdala on regulation of adrenocorticotropic hormone, insulin and fat deposits.
Corticosterone infused intracerebroventricularly inhibits energy storage and stimulates the hypothalamo-pituitary axis in adrenalectomized rats drinking sucrose.
ajpheart.physiology.org /cgi/content/full/286/1/H458   (6078 words)

  
 Endogenous corticosteroids modulate Clostridium difficile toxin A-induced enteritis in rats -- Castagliuolo et al. 280 ...
Plasma corticosterone levels were assessed at 0, 1, and 2 h after injection of purified toxin A in rat ileum.
Plasma corticosterone levels were maintained at a desired level (1, 2, and 4× basal levels) by implanting sc corticosterone pellets as described in Methods.
Augmented ACTH responses to stress in adrenalectomized rats replaced with constant, physiological levels of corticosterone are partially normalized by acute increases in corticosterone.
ajpgi.physiology.org /cgi/content/full/280/4/G539   (4637 words)

  
 Temporal Effects of Stress by Immobilization and Sensitivity of the Isolated Rat Pacemaker to Isoproterenol: Roles of ...
The final average shown for the NI group is the combined average of the control obtained from the individual averages for each IMO group.
Plasma corticosterone levels for all groups is shown in micrograms per milliliter of plasma ± S.E.M. Chronic stress induced by immobilization resulted in a leftward
Kennett GA, Dickinson SL, and Curzon G (1985a) Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone.
jpet.aspetjournals.org /cgi/content/full/306/3/1152   (4390 words)

  
 Mechanisms of Energy Restriction: Effects of Corticosterone on Cell Growth, Cell Cycle Machinery, and Apoptosis -- ...
Effect of corticosterone on cell growth, cell death and cell cycle distribution of TM10 cells.
doses of corticosterone in ethanol for 24, 48, or 72 h and the levels of CDK4 (A) or cyclin D1 (B) proteins in cell lysates were determined by Western blotting as detailed in "Materials and Methods." These data are representative of the results from three independent experiments.
Garvy B. A., King L. E., Telford W. G., Morford L. A., Fraker P. Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis.
cancerres.aacrjournals.org /cgi/content/full/62/18/5280   (6081 words)

  
 ALZET® Bibliography - Administration of Corticosterone
P1649 Gomez-Sanchez,E.P., Venkataraman,M.T., Thwaites,D., Fort,C. ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension.
P1265 Jones,R.B., Beuving,G., Blokhuis,H.J. Tonic immobility and Heterophil/lymphocyte responses of the domestic fowl to corticosterone infusion.
P0709 Fukushima,M., Lupien,J., Bray,G.A. Interaction of light and corticosterone on food intake and brown adipose tissue of the rat.
www.alzet.com /bibliography/CCST.php   (1265 words)

  
 Impaired Diurnal Adrenal Rhythmicity Restored by Constant Infusion of Corticotropin-releasing Hormone in ...
Circadian analysis of plasma corticosterone and glucose in KO and WT mice.
Assenmacher (1979) Effects of lesions of the suprachiasmatic nuclei and p-chlorophenylalanine on the circadian rhythms of adrenocorticotropic hormone and corticosterone in the plasma, and on locomotor activity of rats.
Allen, C., and J.W. Kendall (1967) Maturation of the circadian rhythm of plasma corticosterone in the rat.
www.jci.org /cgi/content/full/99/12/2923   (5060 words)

  
 The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by ...   (Site not responding. Last check: 2007-10-08)
The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by increases in corticosterone and PGE2 -- Newton et al.
The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by increases in corticosterone and PGE
and transient rise in serum corticosterone (CS), and the injection
www.jleukbio.org /cgi/content/abstract/76/4/854   (341 words)

  
 Corticosterone Acts Directly at the Amygdala to Alter Spinal Neuronal Activity in Response to Colorectal Distension -- ...
Corticosterone Acts Directly at the Amygdala to Alter Spinal Neuronal Activity in Response to Colorectal Distension -- Qin et al.
Corticosterone Acts Directly at the Amygdala to Alter Spinal Neuronal Activity in Response to Colorectal Distension.
amygdala by corticosterone sensitizes the lumbosacral spinal neurons
jn.physiology.org /cgi/content/abstract/89/3/1343   (384 words)

  
 Frequent serial fecal corticoid measures from rats reflect circadian and ovarian corticosterone rhythms -- Cavigelli et ...
Frequent serial fecal corticoid measures from rats reflect circadian and ovarian corticosterone rhythms -- Cavigelli et al.
Frequent serial fecal corticoid measures from rats reflect circadian and ovarian corticosterone rhythms
of the circadian corticosterone rhythm within individual rats.
joe.endocrinology-journals.org /cgi/content/abstract/184/1/153   (241 words)

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