
	Where results make sense

Topic: Coxsackie B4 virus

Related Topics

Coxsackie B

Diabetes dictionary

Hypoglycemia

Human leukocyte antigen

DragonStrike (board game)

Hemodialysis

Ochelata, Oklahoma

CNW

Dixieland

Roger Douglas

Edogawa Rampo

New Zealand general election 1999

Birmingham New Street

All Quiet on the Western Front

Under Pressure

	Coxsackie B4 virus
		Coxsackie B4 virus is a virus which can trigger an autoimmune reaction[?] which results in an attack on the beta cells.
		There are several viruses in the Coxsackie family and many of them seem to evoke this response, as do several other agents.
		A genetic predispostion to this seems to be required.
	www.ebroadcast.com.au /lookup/encyclopedia/co/Coxsackie_B4_virus.html (78 words)

	Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry - Nature Medicine
		Coxsackie B4 virus is strongly associated with the development of insulin-dependent diabetes mellitus in humans and shares sequence similarity with the islet autoantigen glutamic acid decarboxylase.
		We infected different strains of mice with Coxsackie B4 virus to discriminate between the two possible induction mechanisms, and found that mice with susceptible MHC alleles had no viral acceleration of diabetes, but mice with a T cell receptor transgene specific for a different islet autoantigen rapidly developed diabetes.
		These results show that diabetes induced by Coxsackie virus infection is a direct result of local infection leading to inflammation, tissue damage, and the release of sequestered islet antigen resulting in the re-stimulation of resting autoreactive T cells, further indicating that the islet antigen sensitization is an indirect consequence of the viral infection.
	www.nature.com /nm/journal/v4/n7/abs/nm0798-781.html (813 words)

	Coxsackie virus and myocardial infarction - Letters to the Editor Townsend Letter for Doctors and Patients - Find ...
		In The Lancet for April 23, 1977 was a report from The King Edward VII Hospital in Sussex, England suggesting that Coxsackie virus infections were causing heart attacks.
		Coxsackie B3 is presumed to be harmless but Coxsackie B4 is said to attack the myocardium and produce damage to the myocardium much like an infarction.
		It is likely that the cold he had was a Coxsackie B4 viral infection and his death was caused by the Coxsackie B4 virus.
	findarticles.com /p/articles/mi_m0ISW/is_2002_July/ai_87720039 (555 words)

	Study of Coxsackie B viral infections in chronic pancreatitis patients from Kerala. Shanmugam JJ, Balakrishnan VV, ...
		Yoon and Co-workers[9] isolated Coxsackie B4 virus from the pancreas of a boy with acute diabetes mellitus.
		The serological evidence Coxsaekie B virus infections in acute pancreatitis patients as reported by other workers,[1],[6],[8] ranged from 5.2% to 90.9%, with an initial testing dilutions ranging from to 1 : 32.Hence, wide variations in positivity rate of Coxsaekie B virus infections may be partly due to the differences in the testing dilutions.
		Whether the Coxsackie B viruses have any etiological association with the genesis of pancreatitis is yet to be studied in detail including the animal experiments using viruses isolated from the pancreatic specimens of the patients.
	www.jpgmonline.com /article.asp?issn=0022-3859;year=1987;volume=33;issue=1;spage=29;epage=31;aulast=Shanmugam (1017 words)

	Enterovirus-Induced Beta-cell damage
		Berg A-K, El-Shebani A, Andersson A, Frisk G. Replication of Coxsackievirus B4 strains in RINm5F cells is dependent on the growth pattern of the cells.
		to glucose in mouse beta-cells infected with coxsackie B or Echo virus.
		Frisk G, Torfason EG, Diderholm H. Reverse radioimmunoassays of IgM and IgG antibodies to Coxsackie B viruses in patients with acute myopericarditis.
	www.kbh.uu.se /enterovirus.htm (1552 words)

	- Vol 26 No 3, September 2002
		Coxsackie B viruses were most often identified in patients presenting with meningitis (31%), lower respiratory tract illness (18%) and gastroenteritis (11%).
		Coxsackie B4 and B5 were the most common serotypes of coxsackie B viruses identified in LabVISE.
		Coxsackie B4 is associated with respiratory disease (summer gripe) mostly in children under 5 years of age.
	www.health.gov.au /internet/wcms/publishing.nsf/Content/cda-pubs-cdi-2002-cdi2603-htm-cdi2603b7.htm (1683 words)

	Defeat Diabetes: Key Findings: Diabetes Is Caused By A Virus
		The candidate virus that the research team focused on was the Coxsackie B4 virus (CVB4), a bug that causes typical viral symptoms and most commonly found in children.
		Using the genetic code of the virus and the latest DNA technology, the Action Researchers were able to grow key parts of the virus and see how the body responds to these, using blood samples of some 40 Type 1 diabetics: teenagers and young adults who had been diagnosed within the last five months.
		Dr Peakman, says: ‘A virus is like an enemy invasion that the body fights with using an ‘infantry’ of anti-viral cells called effector cells, that counteract the virus.
	www.defeatdiabetes.org /Articles/virus030328.htm (672 words)

	ILAR Journal Vol 45(3)
		Third, antigenic epitopes on the virus could be similar to molecules on the host tissue (molecular mimicry), thus causing the generation of antigen-specific T effector cells and/or antibodies that recognize the host target cell, leading to the development of autoimmunity.
		Coxsackie B4 antigens were detected in the islets by immunofluorescence and high levels of antibody against Coxsackie B4 virus were present in the child's serum.
		Coxsackie B virus infection and onset of childhood diabetes.
	dels.nas.edu /ilar_n/ilarjournal/45_3/html/v4503jun.shtml (16568 words)

	Coxsackie B4 virus -- Facts, Info, and Encyclopedia article (Site not responding. Last check: 2007-11-04)
		There are several viruses in the (additional info and facts about Coxsackie) Coxsackie family and many of them seem to evoke this response, as do several other agents.
		A genetic predispostion to this seems to be required.
		See also: (Diabetes caused by a relative or absolute deficiency of insulin and characterized by polyuria) diabetes mellitus, (additional info and facts about diabetes mellitus type 1) diabetes mellitus type 1.
	www.absoluteastronomy.com /encyclopedia/c/co/coxsackie_b4_virus.htm (110 words)

	Archives of Hellenic Medicine
		Coxsackie viruses A and B, which belong to the family of enteroviruses, cause a wide variety of symptoms.
		Histological examination of the liver biopsy revealed hepatitis and serological study revealed a Coxsackie-B4 virus infection.
		Such liver damage in adults from this type of virus has not been referred to in the literature.
	www.mednet.gr /archives/1999-4/391abs.html (114 words)

	Blind World - Requested Article (Site not responding. Last check: 2007-11-04)
		Scientists have found a strong clue that childhood diabetes is linked to a common virus, it was disclosed today.
		The virus might cause the immune system to go into overdrive and start attacking and killing the cells in the pancreas that produce insulin.
		Several years ago a strain of the virus was recovered from the pancreas of a child dying from Type 1 diabetes.
	home.earthlink.net /~blindworld5/RESEARCH/2-05-24-01.htm (525 words)

	Diabetes: Diabetogenic potential of human pathogens uncov... @ HighBeam Research (Site not responding. Last check: 2007-11-04)
		Interestingly, the tropism of the virus was altered in SOCS-1 transgenic (Tg) mice, and CVB3 was detected in islet cells of SOCS-1-Tg mice before [beta]-cell loss and the onset of diabetes.
		One example is when the infecting virus causes direct cytolysis of [beta]-cells, which leads to their destruction and diabetes in the infected host (2,3).
		In the present study, MCMV served as a model virus for HCMV, with the aim to test whether CMV tropism for the [beta]-cell is regulated by IFNs.
	www.highbeam.com /library/doc0.asp?DOCID=1G1:106395070&refid=ip_encyclopedia_hf (6135 words)

	Townsend Letter for Doctors and Patients: Coxsackie virus and myocardial infarction - Letters to the Editor
		In The Lancet for April 23, 1977 was a report from The King Edward VII Hospital in Sussex, England suggesting that Coxsackie virus infections were causing heart attacks.
		Coxsackie B3 is presumed to be harmless but Coxsackie B4 is said to attack the myocardium and produce damage to the myocardium much like an infarction.
		It is likely that the cold he had was a Coxsackie B4 viral infection and his death was caused by the Coxsackie B4 virus.
	www.findarticles.com /p/articles/mi_m0ISW/is_2002_July/ai_87720039 (608 words)

	Action Medical Research - Diabetes: A Key Piece In The Jigsaw
		Coxsackie B4 virus (CVB4), is a bug that causes typical viral symptoms and is most commonly found in children.
		Using the genetic code of the virus and the latest DNA technology, we were able to grow key parts of the virus and see how the body responds to them.
		A virus is like an enemy invasion that the body fights by using an ‘infantry’ of anti-viral cells called effector cells, that counteract the virus.
	www.action.org.uk /touching_lives/2002/autumn/diabetes (1159 words)

	Indian Pediatrics - Editorial
		The pathogenetic linkage between viral infections, including Coxsackie viruses, and renal diseases is difficult to establish(1).We present patient with acute mixed infection with B2 and B4 Coxsackie viruses complicated by glomerulonephritis.
		The role of enteroviruses and especially Coxsackie B viruses in nephritis was suspected previously(2).
		Experimental IgA nephropathy induced by Coxsackie B4 virus in mice.
	www.indianpediatrics.net /aug2005/aug-838-839.htm (525 words)

	Endotext.com - Pediatric Endocrinology, Diabetes Mellitus
		Coxsackie B. Chronic hepatitis C virus infection has also been associated with an increased incidence of diabetes, but it is uncertain as yet if there is a cause-and-effect relationship.
		Coxsackie B virus and rubella virus have been linked with IMD and in few instances, Coxsackie B virus has even been directly isolated from pancreatic tissues of individuals with acute IMD.
		Another study further supports a link between Coxsackie virus and IMD, associating IgM antibodies to Coxsackie B virus as a marker of recent exposure to the virus in newly diagnosed IMD patients and age/sex-matched controls (129).
	www.endotext.org /pediatrics/pediatrics5/pediatrics5.htm (12166 words)

	All the Virology on the WWW Articles : Chronic Diseases With Possible Infectious Etiologies
		It appears that it still cannot be said that Coxsackie B4 virus causes type I diabetes.
		Perhaps as challenging to organic disease dogma as were H. pylori and C. pneumoniae is Borna disease virus and its suspected role in causing mood disorders and schizophrenia.
		The virus was initially isolated from a variety of domestic and wild animals, mostly mammals but also ostriches.
	www.virology.net /Articles/Nash.html (2723 words)

	Voice of the Diabetic, Summer 2002 (Site not responding. Last check: 2007-11-04)
		The research team focused on the Coxsackie B4 virus (CVB4), a bug that causes typical viral symptoms and is most commonly found in children.
		Using the genetic code of the virus and the latest DNA technology, the researchers were able to grow key parts of the virus.
		However, the response of the diabetics was more pronounced, which suggests that the diabetics had been exposed to the virus in the recent past, or repeatedly over time, and so were already primed to take action.
	www.nfb.org /vod/vodsum0202.htm (414 words)

	Cocksackie Virus Induces Diabetes
		The effects of local infection with the Coxsackie B4 virus may be the autoimmune mechanism underlying virus-induced insulin-dependent diabetes mellitus (IDDM).
		The induction of diabetes in this study was a direct result of local infection leading to inflammation, tissue damage, and the release of sequestered islet antigen resulting in the re-stimulation of resting autoreactive cells.
		Coxsackie B4 virus has been implicated in human IDDM and destroys the exocrine pancreas but not the islet cells.
	www.vaccinationnews.com /DailyNews/May2002/CocksackieVirusInducesDiabetes.htm (371 words)

	High frequency of antigenic variants among naturally occurring human Coxsackie B4 virus isolates identified by ...
		The Coxsackie B virus group consists of six serotypes (B1−B6) that are antigenically distinct.
		It is not known, however, whether the different clinical diseases are due to chance infection of particular organs by Coxsackie B4 or due to antigenic variants of Coxsackie B4 that are inherently different in their tissue tropism.
		In an attempt to identify variants of the Coxsackie B4 serotype, we prepared a panel of 18 monoclonal antibodies that neutralized the prototype Coxsackie B4 strain.
	www.nature.com /nature/journal/v300/n5890/abs/300374a0.html (382 words)

	September Surveillance Bulletin (Site not responding. Last check: 2007-11-04)
		Without isolation of the virus or demonstration of a rising titre it is not possible to exclude passive maternal transfer of Coxsackie antibodies.
		Despite intensive investigation (stool culture, Coxsackie B serology, post-mortem myocardial tissue culture) of numerous infants and children hospitalised for myocarditis in the past year, this is a very rare instance of a positive finding.
		Titres of 1:160 to Coxsackie B4, 1:80 to B3, 1:40 to B2 and <1:10 to the remaining serotypes were detected in the blood specimen of a 17 year old female with chest pain and malaise.
	www.niv.ac.za /survbul/current/sep2.htm (3944 words)

	Bopegamage (Site not responding. Last check: 2007-11-04)
		A comparative study of serological parameters in coxsackie virus B4 infected mice by intraperitoneal and oral route.
		The etiological role of coxsackie B4 viruses as one of the triggering factors of IDDM have been indicated in experimental and epidemiological studies.
		Differences in the antibody and the alpha/beta and gamma interferon levels and their temporal kinetics during the different modes of infection were observed.
	biologia.savba.sk /Suppl_9/Bopegamage.htm (175 words)

	[No title] (Site not responding. Last check: 2007-11-04)
		The destruction of beta cells renders them unable to produce insulin, which moves glucose from the blood to the cells, and the patient develops hyperglycaemia (diabetes) due to too much glucose in the blood.
		It has been suggested that at least 27 per cent of all IDDM cases are due to viruses, and in particular Coxsackie B4 virus (CBV4).
		Once the exact receptors and entry routes utilised by the virus to infect the cells have been revealed we will attempt to inhibit virus infection by preventing its entry into beta cells.”;
	www.diabetes.org.uk /research/roundup/regions/port1.htm (135 words)

	Action Medical Research - Key Findings For Diabetes: Action Research study points to viruses
		UK scientists have found strong evidence suggesting that diabetes is caused by a virus, according to new published research.
		The candidate virus that the Action Research team focused on was the Coxsackie B4 virus (CVB4), a bug that causes typical viral symptoms and most commonly found in children.
		Dr Peakman, and his co-worker Dr Ruben Varela-Calvino, says: ‘A virus is like an enemy invasion that the body fights with using an ‘infantry’ of anti-viral cells called effector cells, that counteract the virus.
	www.action.org.uk /news_media/press_releases/168 (1048 words)

	NCFL - The Non-Consolidated Frequency List
		Adenovirus (a virus that causes infections in the lungs, stomach, and intestines): 333, 523, 786
		Epstein-Barr virus (the herpes virus causing mononucleosis): 105, 172, 253, 660, 663, 669, 744, 825, 1032, 1920
		Meningococcus virus (a virus infecting the membranes that envelop the brain and spinal cord): 720
	www.electroherbalism.com /Bioelectronics/FrequenciesandAnecdotes/Non-ConsolidatedFrequencyList.htm (7811 words)

	children with DIABETES - Ask the Diabetes Team
		I recently read a study that mentioned the Coxsackie B virus as producing the same GAD proteins found in people with diabetes, and I'm just wondering what implications this might have for my son.
		To start with the simple bit, if your eight year old daughter is known to have Type 1A antibody positive autoimmune diabetes then her brother has approximately a 5% chance of developing the same form of diabetes.
		In the Coxsackie B4 virus, there is a similarity between a protein called CVB4 and a human GAD fragment called GAD65.
	www.childrenwithdiabetes.com /dteam/2000-08/d_0d_59r.htm (534 words)

	Coxsackie B4 virus Information
		Coxsackie B4 virus is a virus which can trigger an autoimmune reaction which results in destruction of the insulin-producing beta cells of the pancreas, which is one of several different etiologies of diabetes mellitus.
		An absolute deficiency of insulin renders the person a type 1 diabetic.
		View a list of authors or edit this article.
	www.bookrags.com /wiki/Coxsackie_B4_virus (105 words)

Try your search on: Qwika (all wikis)