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Topic: Creatinine


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  Creatinine Blood Levels — Complete medical explanation regarding the production of this chemical waste molecule on ...
Creatinine is a chemical waste molecule that is generated from muscle metabolism.
Normal levels of creatinine in the blood are approximately 0.6 to 1.2 milligrams (mg) per deciliter (dl) in adult males and 0.5 to 1.1 milligrams per deciliter in adult females.
Creatinine levels that reach 2.0 or more in babies and 10.0 or more in adults may indicate the need for a dialysis machine to remove wastes from the blood.
www.medicinenet.com /creatinine_blood_test/article.htm   (501 words)

  
  Creatinine
It measures the actual amount of creatinine which has been excreted, and as such, it is roughly the equivalent of GFR (glomerular filtration rate, which is the percentage kidney function that most kidney patients are familiar with).
It is only roughly equivalent to GFR because some creatinine is also cleared into the urine by the renal tubules (this is called tubular secretion) and this is in addition to the creatinine which is cleared via the glomeruli (which is what glomerular filtration rate measures).
Normally, about 10% of creatinine clearance is due to tubular secretion, but in cases of chronic renal insufficiency, the proportion of creatinine clearance which is due to tubular secretion as opposed to glomerular filtration can rise to 30% and go as high as 50%.
www.igan.ca /id84.htm   (591 words)

  
 Creatinine: The Test
Serum creatinine measurements (along with your age, weight, and gender) also are used to calculate the estimated glomerular filtration rate (EGFR), which is used as a screening test to look for evidence of kidney damage.
Creatinine may be ordered routinely as part of a comprehensive or basic metabolic panel, when someone has non-specific health complaints, is acutely ill, and/or when a doctor suspects kidney dysfunction.
The creatinine blood test may be ordered, along with the BUN test, at regular intervals when the patient has a known kidney disorder or has a disease that may affect kidney function or be exacerbated by dysfunction.
www.labtestsonline.org /understanding/analytes/creatinine/test.html   (707 words)

  
 Creatinine Clearance
Because all the creatinine filtered by the kidneys in a given time interval is excreted into the urine, creatinine levels are equivalent to the glomerular filtration rate (GFR); the rate at which the kidneys process blood through the glomerular system.
The creatinine clearance test is used to diagnose renal dysfunction and is also used to evaluate the progression of renal disease.
A minimum creatinine clearance of 10ml/min is necessary to maintain life without the use of renal or peritoneal dialysis.
www.rnceus.com /renal/renalcc.html   (304 words)

  
 A Brief Review of Creatinine Concentration   (Site not responding. Last check: 2007-10-15)
Creatinine, in actuality, has poor sensitivity in diagnosing renal disease in the dog and cat because three-fourths of renal function must be lost before abnormalities in creatinine concentration are seen.
Creatinine is used to evaluate GFR because it is almost exclusively cleared by glomerular filtration and is neither secreted nor absorbed by the renal tubules.
Creatinine is a relatively large molecule (113 daltons) that is primarily concentrated in the urine bathing the abdomen and is slow (over 4 hours) to diffuse into the blood.
www.vet.uga.edu /vpp/clerk/miller/index.htm   (3057 words)

  
 Creatinine - Serum - Health Centers - WHIOTV.com | WHIO
Creatinine is a breakdown product of creatine, which is an important part of muscle.
Creatinine can be converted to the ATP molecule, which is a high-energy source.
Creatinine is excreted from the body entirely by the kidneys.
www.whiotv.com /encyclopedia/6864516/detail.html   (659 words)

  
 Creatinine - urine
A measurement of the serum creatinine level is often used to evaluate kidney function.
Urine creatinine levels can be used as a screening test to evaluate kidney function, or can be part of the creatinine clearance test.
Creatinine is a breakdown product of creatine, which is an important constituent of muscle.
www.stlukes-stl.com /ency/article/003610.htm   (553 words)

  
 Creatinine
The revised levels at which creatinine may be considered dilute (<20 ml/dL) or abnormally dilute (<=5 mg/dL) are based on the critical points that SAMSHA has set as decision points for interpreting dilute or substituted urine specimens.
Creatinine is a metabolic byproduct of protein metabolism, which normally appears in urine in relatively constant quantities over a 24-hour period with regular liquid consumption.
Therefore, urine creatinine can be used as an indicator of urine water content or as a marker value for urine.
www.dtpm.ws /Creatinine.htm   (220 words)

  
 Creatinine clearance
The creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood, usually based on measurements of a 24-hour urine sample and a blood sample drawn at the end of the 24-hour period.
Because creatinine is found in stable plasma concentrations, is freely filtered and not reabsorbed, and is minimally secreted by the kidneys, creatinine clearance is used to estimate the glomerular filtration rate (GFR).
Creatinine is used for this purpose, since it is normally present in the body and very little creatinine is reabsorbed after it is filtered.
www.umm.edu /ency/article/003611.htm   (945 words)

  
 Serum creatinine
Creatinine is freely filtered and therefore the serum creatinine level depends on the Glomerular Filtration Rate (GFR).
The serum creatinine level does not rise until at least half of the kidney's nephrons are destroyed or damaged.
Measurement of serum creatinine is important because it is a inexpensive and reliable indicator of renal function.
www.rnceus.com /renal/renalcreat.html   (476 words)

  
 Creatinine - urine - Evanston Northwestern Healthcare   (Site not responding. Last check: 2007-10-15)
The creatinine urine test measures the amount of creatinine in urine.
Urine creatinine levels can be used as a screening test to evaluate kidney function, or as part of the creatinine clearance test.
Creatinine is a waste product, that is, it cannot be used by cells for any constructive purpose.
www.enh.org /healthandwellness/encyclopedia/ency/article/003610.aspx   (669 words)

  
 Creatinine Tests Before CT Scans
Creatinine is a normal breakdown product of muscle tissue and if your kidneys are functioning normally, they will excrete creatinine into your urine and eliminate it from your body - otherwise it will build up in your system and your creatinine level will rise.
That's why a creatinine blood test is used to determine if you have normal or impaired kidney function.
If the creatinine is mildly elevated (between 1.3 and 2.0, which indicates abnormal kidney functioning) the radiologist may proceed with the CT scan, but lower the dye dose.
healthlink.mcw.edu /article/973896344.html   (359 words)

  
 Creatinine Test | AHealthyMe.com
The creatinine test is used to diagnose impaired kidney function and to determine renal (kidney) damage.
The creatinine test is used to measure the amount of creatinine in the blood.
Creatinine is excreted entirely by the kidneys, and therefore is directly related to renal function.
www.ahealthyme.com /topic/topic100586675   (590 words)

  
 Creatinine and Creatinine Clearance
Creatinine and creatinine clearance tests measure creatinine levels in your blood and urine to provide information about how well your kidneys are working.
The creatinine clearance value is calculated from the amounts of creatinine in the urine and blood and from the volume of urine.
A high blood creatinine level is usually associated with a low creatinine clearance because creatinine in the blood is removed, or filtered, by the kidneys.
www.webmd.com /hw/kidney_failure/hw4322.asp   (1821 words)

  
 URI APhA-ASP Creatinine Clearance Project
The calculation of creatinine clearance is an indicator of glomerular filtration rate (GFR) and is used clinically as an indicator of overall renal function.
Creatinine is a byproduct of creatinine metabolism that occurs in the muscle.
Creatinine is one of the indicators of renal function.
www.uri.edu /student_organizations/asp/resources/creatinine.html   (461 words)

  
 Renally excreted drug dosing review   (Site not responding. Last check: 2007-10-15)
Thus, an estimate of creatinine clearance is necessary for determining the appropriate dosage of renally excreted drugs.
Creatinine clearance can either be measured by a timed urine collection or estimated from serum creatinine.
Use of a very low serum creatinine (0.5 mg% or less) in the C&G equation leads to a falsely elevated CL Therefore, many practitioners designate 0.7 mg% as the minimum SCr which should be used in the equation.
www.rxkinetics.com /renal.html   (1995 words)

  
 Creatinine: Common Questions   (Site not responding. Last check: 2007-10-15)
Creatinine levels may be 10%-30% higher in people who eat a diet that is very high in meat.
Creatinine and urea are the primary tests used to check how well the kidneys filter waste products from your blood.
Creatinine levels are generally slightly lower in pregnancy.
www.labtestsonline.org.uk /understanding/analytes/creatinine/faq.html   (345 words)

  
 Healthopedia.com - Creatinine (Serum Creatinine, Serum Creatinine Level, Creatinine Level in the Blood)
Creatinine is a waste product made by the body during regular metabolism.
The level of creatinine in the blood is a good measure of overall kidney function.
To perform a serum creatinine test, a blood sample is taken from a vein on the forearm or hand.
www.healthopedia.com /creatinine   (417 words)

  
 Medscape MEDLINE search: Creatinine
Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass grafting.
OBJECTIVES: We sought to evaluate renal function assessed on the basis of calculated creatinine clearance as a predictor of early mortality and postoperative complications in patients undergoing coronary artery bypass grafting and to assess whether calculated creatinine clearance is superior to serum creatinine concentration in predicting early death postoperatively.
Extrapolation of reciprocal creatinine plot is not reliable in predicting the onset of dialysis in patients with progressive renal insufficiency.
search.medscape.com /uslclient/searchMedline.do?queryText=Creatinine   (1324 words)

  
 Creatinine - Wikipedia, the free encyclopedia
Creatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
A higher than normal creatinine and BUN can also be indicative of dehydration when BUN-to-creatinine ratio is abnormal, with BUN levels rising higher than creatinine levels.
Measuring serum creatinine is a simple test and it is the most commonly used indicator of renal function.
en.wikipedia.org /wiki/Creatinine   (419 words)

  
 Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements   (Site not responding. Last check: 2007-10-15)
Urinary creatinine concentrations, specific gravity, and osmolality are common methods for adjusting dilution and for determining whether a spot urine sample is valid for assessing chemical exposures.
Urine creatinine concentrations were used to adjust the urinary concentrations of pesticides and metabolites of pesticides and phthalates in subsets of adults participating in NHANES III.
Because urinary creatinine concentrations are so widely used to adjust or correct urinary concentrations of environmental and workplace chemicals or their metabolites, the formation of urinary creatinine and the ways in which various factors may affect its concentration are important to review.
www.ehponline.org /members/2004/7337/7337.html   (6062 words)

  
 Creatinine definition - Medical Dictionary definitions of popular medical terms
Although it is a waste, creatinine serves a vital diagnostic function.
(In the metric system, a milligram is a unit of weight equal to one-thousandth of a gram, and a deciliter is a unit of volume equal to one-tenth of a liter.) Muscular young or middle-aged adults may have more creatinine in their blood than the norm for the general population.
Creatinine Blood Test - Learn more about the Creatinine blood test, including a description, reasons for production, importance of checking levels, and interpretation of blood Creatinine level results.
www.medterms.com /script/main/art.asp?articlekey=12550   (459 words)

  
 Kidneys,creatinine levels
Creatinines in end stage renal failure usually run 10 or less for the less muscular.
A creatinine of 2 means that half of the kidney function is lost.
If the creatinine is around 5, about 80- 90% of their kidney function is lost.
www.medhelp.org /forums/urology/archive/232.html   (504 words)

  
 Creatinine clearance - Wikipedia, the free encyclopedia
In general, creatinine clearance is the removal of creatinine from the body.
Clinically, creatinine clearance is a useful measure for estimating the glomerular filtration rate (GFR) of the kidneys.
Creatinine is used because it fulfills these requirements (though not perfectly) and it is produced naturally by the body (creatinine is a metabolite of creatine, which is found in muscle).
en.wikipedia.org /wiki/Creatinine_clearance   (440 words)

  
 Creatinine: The Test   (Site not responding. Last check: 2007-10-15)
A combination of blood and urine creatinine levels may be used to calculate a "creatinine clearance." This measures how effectively your kidneys are filtering small molecules like creatinine out of your blood.
Creatinine may be part of a routine blood test, widely used when someone has non-specific health complaints, or when your doctor suspects kidney problems.
As creatinine levels are related to the amount of muscle the person has, low levels may be a consequence of decreased muscle mass (such as in the elderly), but may also be occasionally found in advanced liver disease.
www.labtestsonline.org.uk /understanding/analytes/creatinine/test.html   (329 words)

  
 Adult Health Advisor 2005.4: Blood (Serum) Creatinine Test
Creatinine is carried by the blood to the kidneys, which filter it from the body into the urine.
Creatinine is measured to see how well your kidneys are working.
The normal range for creatinine in the blood is 0.8 to 1.4 milligrams per deciliter (mg/dL).
www.med.umich.edu /1libr/aha/aha_creatini_crs.htm   (583 words)

  
 Creatinine
A measurement of the serum creatinine level is often used to evaluate
Creatinine is a breakdown product of creatine, which is an important
Creatinine is a waste product, that is, it cannot be used by cells for any
www.geocities.com /worldwidebarnes/Creatinine.htm   (1473 words)

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