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Topic: Curcumin

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	Linus Pauling Institute at Oregon State University
		Curcumin is readily conjugated in the intestine and liver to form curcumin glucuronides and curcumin sulfates or reduced to hexahydrocurcumin (Figure 2) (3).
		In contrast, curcumin was not detected in the liver tissue of patients with liver metastases of colorectal cancer after the same dose of oral curcumin (8), suggesting that oral curcumin administration may not effectively deliver curcumin to tissues outside the gastrointestinal tract.
		Curcumin inhibited apoptosis induced by the tumor suppressor protein p53 in cultured human colon cancer cells (28, 29), and one study found that curcumin inhibited apoptosis induced by several chemotherapeutic agents in cultured breast cancer cells at concentrations of 1-10 micromoles/liter (30).
	lpi.oregonstate.edu /infocenter/phytochemicals/curcumin/index.html (3319 words)

	Curcumin and Curcuminoids
		Curcumin’s cholesterol-lowering actions include interfering with intestinal cholesterol uptake, increasing the conversion ofcholesterol in to bile acids by increasing the activity of hepatic cholesterol-7-alpha-hydroxylase, the rate-limiting enzyme of bile acid synthesis; and increasing the excretion of bile acids via its choleretic effects.
		Curcumin is a major component of the Curcuma species, which is commonly used as a yellow coloring and flavoring agent in foods.
		Curcumin possesses anti-inflammatory activity and is a potent inhibitor of reactive oxygen-generating enzymes, such as lipoxygenase/cyclooxygenase, xanthine dehydrogenase/oxidase and induc-ible nitric oxide synthase.
	www.herbalfields.com /curcumin.html (1876 words)

	Curcuma longa
		Curcumin is found to be a potent radiosensitizer in p53 mutant prostate cancer cell line PC-3 and it acts by overcoming the effects of radiation-induced prosurvival gene expression in prostate cancer.
		Curcumin was found to decrease the Ehrlich's ascites carcinoma cell number, by the induction of apoptosis in the tumor cells as evident from flow-cytometric analysis of cell cycle phase distribution of nuclear DNA &=11676493 oligonucleosomal fragmentation.
		Curcumin was shown to be responsible for the inhibition of AK-5 tumor (a rat histiocytoma) growth by inducing apoptosis in AK-5 tumor cells via redox signalling and caspase activation.
	www.herbmed.org /herbs/herb9.htm (6131 words)

	curcumin - multiple sclerosis encyclopaedia
		Curcumin (Diferuloylmethane) is a compound found in the Indian curry spice, tumeric.
		Research using curcumin, the active ingredient of tumeric, in EAE, a mouse model of multiple sclerosis, has shown that it may be of benefit to people with MS.
		Curcumin is not to be confused with cumin which is a completely different spice with a similar name.
	www.mult-sclerosis.org /curcumin.html (328 words)

	Curcumin - Wikipedia, the free encyclopedia
		Curcumin is the active ingredient of the Indian curry spice turmeric.
		Curcumin is known for its antitumor, antioxidant, anti-amyloid and anti-inflammatory properties.
		Curcumin, when eaten, is absorbed effectively as shown by the numerous studies and research on human and animal research.
	en.wikipedia.org /wiki/Curcumin (816 words)

	Le Magazine, July 2002 - Report: A Report On Curcumin's Anti-Cancer Effects
		Curcumin arrests the growth of cancer cells in the G2 stage.
		The actions of curcumin have been the subject of presentations at major meetings on cancer research, and the object of study by researchers at the most prestigious universities in the world.
		The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
	www.lef.org /magazine/mag2002/jul2002_report_curcumin_01.html (2934 words)

	Curcumin Cures (Site not responding. Last check: 2007-10-08)
		Thus, chemopreventive activity of curcumin is observed when it is administered prior to, during, and after carcinogen treatment as well as when it is given only during the promotion/progression phase (starting late in premalignant stage) of colon carcinogenesis.
		Curcumin, a diferuloylmethane, is a major active component of the food flavor turmeric (Curcuma longa) that exhibits anticarcinogenic properties in vivo...
		Curcumin treatment caused a significant induction of the glutathione S-transferase (GST) isozyme (detoxification enzyme)…and these studies suggest that curcumin may be an effective protective agent against cataractogenesis (formation of cataracts) induced by lipid peroxidation (oxidation of fat).
	www.agelesscures.com /id19.html (4468 words)

	Curcumin Research : by Ray Sahelian, M.D. Buy Curcumin and Turmeric (Site not responding. Last check: 2007-10-08)
		Curcumin -induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.
		Curcumin and its metabolites were detected and quantitated by high-performance liquid chromatography with detection by UV spectrophotometry or mass spectrometry.
		Curcumin may have been the herb that helped your lichen planus, and we eagerly await other reports from those with lichen planus to see if your response was an isolated case or whether in fact curcumin is helpful for lichen planus.
	www.raysahelian.com /curcumin.html (4063 words)

	CURRY POWDER: Curcumin
		As thus obtained, curcumin crystallizes in amber-yellow prisms, appearing orange-yellow in reflected light, insoluble in water and diluted acids, sparingly soluble (1 in 2000) in benzene (Daube's solvent, which refuses to dissolve the resins); easily soluble in ether, chloroform, and alcohol; also in diluted alkaline solutions with a striking red-brown, fluorescent color.
		Chemically, curcumin is a substituted aromatic oxyacid, yielding vanillin with weak oxidizers, and protocatechuic acid when fused with caustic potash.
		Curcumin: Confusion exists in present usage of this word; Curcumin is the name for turmeric in many countries; however, expensive products called "Curcumin" are now being sold with the vitamins at health food outlets, and research on curcumin abounds in current medical literature.
	www.lionsgrip.com /curcurcumin.html (1765 words)

	Curcumin - Promote a Healthy Inflammation Response - Curcumin (Site not responding. Last check: 2007-10-08)
		Curcumin is a natural health enhancer with a long history of use in Ayurvedic (Indian) medicine for supporting a healthy inflammatory response, promoting detoxification of the body, and easing occasional minor digestive upset.
		This curcumin extract is a powerful 18:1 concentrate, meaning it takes 18 pounds of the dry herb to equal the potency of one pound of the dry extract.
		Research suggests curcumin may also be effective in comforting symptoms of occasional digestive upset.
	www.immunesupport.com /curcumin.htm (212 words)

	Flu Wiki - Consequences - Curcumin
		Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells.
		Also in animal studies, curcumin was found to decrease the nephrotoxicity due to doxorubicin and to decrease chromosomal aberrations due to bleomycin.
		Curcumin is a constituent of the common kitchen spice Tumeric.
	www.fluwikie.com /pmwiki.php?n=Consequences.Curcumin (854 words)

	Curcumin C3 Complex® with Green Tea Extract - Pure Prescriptions
		Curcumin C3 Complex® is a unique, patented extract of Curcuma longa root, commonly known as “Turmeric".
		Pure Prescriptions' very own Dr. Ankur Chandra, MD discusses the medicinal benefits of Curcumin and why these plant-derived chemicals have generated considerable interest recently for their potential to combat human disease such as cancer, inflammation, and atherosclerosis...
		“Curcumin C3 Complex has proven to be unique in its ability to act not only as a powerful antioxidant but to exhibit exemplary anti-inflammatory actions.
	www.pureprescriptions.com /curcumin.asp (517 words)

	Curcumin Inhibits Formation of Amyloid {beta} Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo -- Yang ...
		Curcumin binds to peptide sequences that form fibrils or protofibrils Shown are a schematic diagram and table of curcumin binding experiments.
		Curcumin crosses the blood-brain barrier and binds to plaques in vivo.
		or absent by preabsorption of curcumin with fibril-forming A
	www.jbc.org /cgi/content/full/280/7/5892 (5917 words)

	Curcumin (Site not responding. Last check: 2007-10-08)
		Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.
		This agent was shown to decrease the proliferative potential and induce the apoptosis potential of both androgen-dependent and androgen-independent prostate cancer cells in vitro, largely by modulating the apoptosis suppressor proteins and by interfering with the growth factor receptor signaling pathways as exemplified by the EGF-receptor.
		RESULTS: Curcumin causes a marked decrease in the extent of cell proliferation as measured by the BrdU incorporation assay and a significant increase in the extent of apoptosis as measured by an in situ cell death assay.
	www.youngagain.com /curcumin2.html (595 words)

	CURCUMIN + QUERCETIN
		Curcumin is effective at inhibiting 5-lipoxygenase and subsequently HETE, a survival factor for prostate, breast, and pancreatic cancers (Ghosh et al.
		CURCUMIN An overview of the good properties of curcumin related to cancer in general, which includes prostate cancer.
		Given that other studies have shown curcumin is non-toxic, these results should be followed by a test of the spice in both animal models of melanoma and in human trials, they say.
	www.altered-states.net /barry/cancer/curcumin.htm (2533 words)

	Curcumin Information - Curcumin Supplement -
		Curcumin (Curcuma longa) is the source of the spice Turmeric, and is used in curries and other spicy dishes from India, Asia, and the Middle East.
		Curcumin is what gives the Curry its characteristic bright yellow color and strong taste.
		In modern times, research has focused on Curcumin's antioxidant, anti-inflammatory, anticarcinogenic, and antimicrobial properties, and on its use in cardiovascular disease, gastrointestinal disorders, and as a treatment for the liver.
	www.curcumin.net (336 words)

	USNews.com: Health: In Brief: Cancer: Curcumin and melanoma
		Small doses of curcumin, a spice ground from the turmeric root and a common ingredient in curry, not only stopped the growth of melanoma cells in the lab but also caused the cells to self-destruct, say researchers from the University of Texas's M. Anderson Cancer Center in Houston.
		The researchers tested curcumin on lab-grown melanoma cells to see if the spice could stop the cells from surviving and reproducing.
		"Curcumin is a perfect alternative [to chemotherapy], but we have to prove that it works," he says.
	www.usnews.com /usnews/health/briefs/cancer/hb050711a.htm (488 words)

	Consumption of the Putative Chemopreventive Agent Curcumin by Cancer Patients: Assessment of Curcumin Levels in the ...
		Consumption of the Putative Chemopreventive Agent Curcumin by Cancer Patients: Assessment of Curcumin Levels in the Colorectum and their Pharmacodynamic Consequences -- Garcea et al.
		Consumption of the Putative Chemopreventive Agent Curcumin by Cancer Patients: Assessment of Curcumin Levels in the Colorectum and their Pharmacodynamic Consequences
		The concentrations of curcumin in normal and malignant colorectal
	cebp.aacrjournals.org /cgi/content/abstract/14/1/120 (389 words)

	Turmeric - Wikipedia, the free encyclopedia
		"Curcumin has been used for thousands of years as a safe anti-inflammatory in a variety of ailments as part of Indian traditional medicine," Gregory Cole, Professor of medicine and neurology at the David Geffen School of Medicine at UCLA said.
		The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.
		Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats.
	en.wikipedia.org /wiki/Turmeric (1106 words)

	Herbal Descriptions - Curcumin - Curcuma longa (Site not responding. Last check: 2007-10-08)
		Curcumin increases the secretion of bile by stimulating the bile duct.
		Curcumin also protects the liver by detoxification, stimulating the gall bladder and scavenging free radicals.
		Curcumin is being studied as an anti-inflammatory, and for other potential medical uses.
	www.viable-herbal.com /herbdesc1/1curcumi.htm (389 words)

	Curcumin, Potent Antioxidant, Anti-Inflammatory and Cancer Fighter, qnt: 180 caps, size: 500 mg (Site not responding. Last check: 2007-10-08)
		Curcumin is a potent antioxidant with specific antiviral, anti-inflammatory, anti-cancer and cholesterol-lowering effects.
		Curcumin is an antioxidant extract from the spice turmeric that produces a wide range of health benefits.
		In a wide range of cancer cells, curcumin has been shown to induce cell shrinkage, chromatin condensation, DNA fragmentation and block cellular signal transduction, all of which are characteristics of apoptosis according to an article published in the journal Nutrition and Cancer USA (26/1 1996).
	www.youngagain.com /curpotananan.html (651 words)

	Curcumin/Turmeric (Curcuma longa)
		The rats fed curcumin also performed better on memory tests than rats on normal diets...
		And preliminary studies at Vanderbilt University suggest that curcumin may block the progression of multiple sclerosis...
		Thromboxane is a potent inflammatory compound produced by the body in response to injury or irritation.
	qualitycounts.com /fpcurcumin.html (1525 words)

	Curcumin (Curcurmin) (Site not responding. Last check: 2007-10-08)
		A new study published in the current issue of the journal Clinical Cancer Research reveals that curcumin -- the yellow pigment in turmeric, a major spice in curry -- can stop the growth and spread of colorectal and breast cancers.
		In a host of studies, M.D. Anderson researchers are showing that curcumin, the pungent yellow spice in both turmeric and curry powders, has potent anti-cancer properties.
		One of the things that sets curcumin apart from most other anti-cancer supplements, is that this phenolic can actually block chemicals from getting inside cells.
	www.thepowerhour.com /curcurmin.htm (429 words)

	Curcumin 95 by Jarrow Formulas Inc - Curcumin 95
		Curcumin 95 by Jarrow Formulas on wholesale prices!
		Curcumin 95 is an 18:1 extract of the antioxidants found in the spice turmeric root.
		Curcumin 95 contains 95% curcuminoids (including curcumin, demethoxycurcumin and bisdemethoxy-curcumin) which are antioxidants.
	www.herbsmd.com /sp/xq/asp/store.CUR/qx/default.htm (114 words)

	Curcumin - Highest amount per capsule and per bottle (via CobWeb/3.1 planetlab2.cs.virginia.edu) (Site not responding. Last check: 2007-10-08)
		Curcumin - Highest amount per capsule and per bottle (via CobWeb/3.1 planetlab2.cs.virginia.edu)
		Ground Turmeric is used worldwide as a seasoning, the main ingredient in curry, and as a source for Curcumin (Turmeric contains approximately 5% Curcumin) and its therapeutic effects.
		These include Curcumin, demethoxycurcumin and bisdemethoxycurcumin in a concentrated extract for maximum potency.
	www.turmeric-curcumin.com.cob-web.org:8888 (205 words)

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