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Topic: Cutaneous receptor

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Mechanoreceptor

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	Sensory receptor - Wikipedia, the free encyclopedia
		Odour receptors in olfactory receptor neurons, for example, are activated by interacting with molecular structures on the odor molecule.
		A sensory receptor's adequate stimulus is the stimulus modality for which it possesses the adequate sensory transduction apparatus.
		Cutaneous receptors are sensory receptors found in the dermis or epidermis.
	en.wikipedia.org /wiki/Sensory_receptor (408 words)

	Cutaneous Receptors (Site not responding. Last check: 2007-08-21)
		The different classes of cutaneous receptors, like all sensory receptors, are defined in two ways: by their anatomical structures, and by the type of electrical signals they send along their nerve fibres.
		Pressure on the skin causes a sustained discharge of nerve impulses; as with the Merkel cell, the frequency of nerve impulses is proportional to the intensity of the stimulus.
		The pacinian corpuscle is a rapidly adapting receptor.
	www.ilo.org /encyclopaedia/?print&nd=857400179 (2911 words)

	Cancer Information, Research, and Treatment for all Types of Cancer \| OncoLink
		A T-cell receptor gamma polymerase chain reaction assay using capillary electrophoresis for the diagnosis of cutaneous T-cell lymphomas.
		Mycosis fungoides is a malignant T-cell lymphoproliferative disease with a predilection for cutaneous involvement.
		Cutaneous T cell lymphomas are characterized by an accumulation of malignant clonal lymphocytes in the skin and occasionally in the blood.
	www.oncolink.upenn.edu /types/article.cfm?c=18&s=61&ss=296&id=8551 (3351 words)

	Specialty Laboratories ::: we help doctors help patients
		Cytokines and soluble interleukin-2 receptors in rheumatoid arthritis.
		Increased serum concentrations of the soluble interleukin-2 receptor in cutaneous T-cell lymphoma.
		Soluble interleukin-2 receptors in serum and bile of liver transplant recipients.
	www.specialtylabs.com /books/display.asp?id=793 (781 words)

	T-cell subtype - cutaneous
		"Cutaneous T cell lymphoma (CTCL) is a lymphoma of T cell (a type of white blood cell that is responsible for immune function) origin that affects the skin.
		Non-cutaneous T-cell lymphomas that are positive for the CD4 receptor are predominantly of the nodal subtype.
		EPOCH for refractory T-cell NHL Chemotherapy with etoposide, vincristine, doxorubicin, bolus cyclophosphamide, and oral prednisone in patients with refractory cutaneous T-cell lymphoma.
	www.lymphomation.org /type-t-cell-cutaneous.htm (641 words)

	PNS Unit
		The sensory receptor with endings in the periphery is referred to as the primary sensory neuron or the primary afferent, meaning that it is the first neuron in the sensory input chain.
		Cutaneous receptors are primary afferent fibers with their sensory region in the layers of skin.
		The receptor is formed from the terminal of an afferent fiber that has its cell body in, or near, a dorsal root ganglion or cranial nerve ganglion.
	www.med.uiuc.edu /m1/neurosci/Web_Neuro_2001/protected/curriculum/Unit_07_01_PNS/PNS-all.htm (11342 words)

	Differences in clinical behaviour and immunophenotype between primary cutaneous and primary nodal anaplastic large cell ... (Site not responding. Last check: 2007-08-21)
		The histological, immunophenotypic and clinical features of 19 primary cutaneous anaplastic large cell lymphomas (cutaneous ALCL) were compared with those of 18 primary nodal anaplastic large cell lymphomas (nodal ALCL) of T-cell or null cell type.
		Patients with cutaneous ALCL were generally older (median 61 years) than patients with nodal ALCL (median 24 years) and, in contrast to the latter group, did not show bimodal age distribution.
		The better survival of cutaneous ALCL patients could not be ascribed to differences in age, stage or initial mode of treatment.
	www.meb.uni-bonn.de /cgi-bin/mycite?ExtRef=ICDB/94010779 (305 words)

	AEE788, a Dual Tyrosine Kinase Receptor Inhibitor, Induces Endothelial Cell Apoptosis in Human Cutaneous Squamous Cell ...
		Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathway and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).
		Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice.
		Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis.
	clincancerres.aacrjournals.org /cgi/content/full/11/5/1963 (5524 words)

	Skin Research Center: Immunobiology of Cutaneous T Cell Lymphoma - Dermatology
		In two distinct ways, they were able to demonstrate that these peptides originate, at least in large measure, from distinctive components of the T cell receptor chains of the malignant cells.
		These peptides are derived from the clone-specific T cell receptor, and the results may also explain how normal T cells are regulated through an idiotypic network.
		These include epitopes on particular TCR chains, the CD45RO isoform preferentially expressed by memory T cells, and the cutaneous lymphoid associated antigen (CLA) shown by Picker and his colleagues to be the homing receptor for skin-seeking T cells.
	info.med.yale.edu /dermatology/src/guides/cutaneoustcell.html (2991 words)

	Sympathetic nonnoradrenergic cutaneous vasoconstriction in women is associated with reproductive hormone status -- ...
		Lundberg, JM, and Modin A. Inhibition of sympathetic vasoconstriction in pigs in vivo by the neuropeptide Y-Y1 receptor antagonist BIBP 3226.
		receptors in hypothalamic neuroendocrine areas are up-regulated by estradiol and decreased by progesterone cotreatment in the ovariectomized rat.
		receptor gene expression during the estrous cycle: role of progesterone receptors.
	ajpheart.physiology.org /cgi/content/full/282/1/H264 (5474 words)

	Cutaneous lymphomas
		The term primary cutaneous lymphomas designates a heterogeneous group of lymphoproliferative disorders arising from skin-homing T and B cells which present in the skin with no evidence of extracutaneous disease at the time of diagnosis and six months thereafter (1-3).
		The diagnosis of cutaneous lymphomas is made by recognizing the clinical manifestations and is supported by laboratory tests.
		Southern blot analysis of genes coding for Ig or for T-cell receptor was the method used in initial studies, which showed evidence for the monoclonal nature of both cutaneous T cell lymphoma (CTCL) and cutaneous B cell lymphoma (CBCL).
	www.mf.uni-lj.si /acta-apa/acta-apa-01-2/2-2-01.html (1609 words)

	WAO Educational Programs: World Allergy Forum
		Since the skin of patients with atopic dermatitis lacks an intact stratum corneum, dermal fibronectin receptors might be uncovered and increase the adherence of S. aureus (32;33).
		Leung et al demonstrated that staphylococcal exotoxins were able to upregulate the expression of the cutaneous homing receptor cutaneous lymphocyte antigen (CLA) on normal PBMC by induction of IL-12.
		Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T-cell-dependent response.
	www.worldallergy.org /educational_programs/world_allergy_forum/neworleans/werfel.shtml (4977 words)

	The Cutaneous Response in Humans to Treponema pallidum Lipoprotein Analogues Involves Cellular Elements of Both Innate ...
		B, Cutaneous inflammatory responses elicited 48 h after intradermal inoculation with the designated doses of lipidated and nonlipidated hexapeptides corresponding to the N terminus of the 17-kDa T.
		In situ identification of mononuclear cells in cutaneous infiltrates in discoid lupus erythematosus, sarcoidosis and secondary syphilis.
		Chemokines and chemokine receptors in the regulation of dendritic cell trafficking.
	www.jimmunol.org /cgi/content/full/166/6/4131 (6913 words)

	CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking -- Soler et al. 101 (5): 1677 -- Blood
		For each cutaneous lymphocyte donor, peripheral blood was compared with the database of 10 healthy donors presented in Figures 2 and 3.
		The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.
		Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity.
	www.bloodjournal.org /cgi/content/full/101/5/1677 (4974 words)

	eMedicine - Cutaneous CD30+ (Ki-1) Anaplastic Large-Cell Lymphoma : Article by Chung-Che Chang, MD, PhD (Site not responding. Last check: 2007-08-21)
		Age: Patients with primary cutaneous forms of ALCL are generally older (median age, 61 y) than patients with the systemic form of ALCL (median age, 24 y) and, in contrast to the latter group, do not show a bimodal age distribution.
		Patients with widespread systemic and cutaneous disease at first presentation should be considered to have the systemic form with skin involvement.
		CT scan of the chest and the abdomen may be performed for staging of lymphoma and for differentiating the primary cutaneous form from the systemic form involving the skin.
	www.emedicine.com /derm/topic534.htm (2615 words)

	A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations -- Baekkevold et al. ...
		A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations -- Baekkevold et al.
		The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells.
		Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes.
	www.jem.org /cgi/content/full/201/7/1045 (2871 words)

	Differential Effects of NGF and BDNF on Axotomy-Induced Changes in GABAA-Receptor-Mediated Conductance and Sodium ...
		Whole cell voltage-clamp recordings were obtained from identified cutaneous DRG afferent neurons with the use of the patch-clamp
		Identified cutaneous afferent DRG neurons ranging in size from 35 to 60 µm diam and corresponding to neurons with myelinated
		Cutaneous afferent neurons from axotomized animals whose transected nerve stumps were perfused with BDNF displayed GABA-induced
	jn.physiology.org /cgi/content/full/78/1/31 (5991 words)

	Gamma Delta T-cell Lymphoma of the skin
		T cells have receptors on their surfaces which allow it to interact with other cells and proteins.
		Thus, it is important to distinguish this variant of a cutaneous T-cell lymphoma from mycosis fungoides.
		The pathologist is responsible for analyzing the T-cell receptor type as well as examining special stains that will aid in the diagnosis.
	www.thedoctorsdoctor.com /diseases/ctcl_gammadelta.htm (1618 words)

	Heat stress induces ultrastructural changes in cutaneous capillary wall of heat-acclimated rock pigeon -- Arieli et al. ...
		Heat stress induces ultrastructural changes in cutaneous capillary wall of heat-acclimated rock pigeon -- Arieli et al.
		In heat-acclimated rock pigeons, cutaneous water evaporation is the major cooling mechanism when exposed at rest to an extremely
		Cutaneous blood flow in the pigeon Columba livia: its possible relevance to cutaneous water evaporation
	ajpregu.physiology.org /cgi/content/abstract/277/4/R967 (228 words)

	Immunopathogenesis and therapy of cutaneous T cell lymphoma -- Kim et al. 115 (4): 798 -- Journal of Clinical ...
		Chemokine receptor expression on neoplastic and reactive T cells in the skin at different stages of mycosis fungoides.
		The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells.
		Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sezary syndrome and mycosis fungoides.
	www.jci.org /cgi/content/full/115/4/798 (7179 words)

	Effects of cutaneous receptor stimulation on muscular atrophy developed in hindlimb unloading condition -- De-Doncker ...
		Effects of cutaneous receptor stimulation on muscular atrophy developed in hindlimb unloading condition -- De-Doncker et al.
		Stimulation of the cutaneous receptors was performed by fitting a latex balloon to the two plantar surfaces of hindfeet (Fig.
		cutaneous mechanoreceptors of the rat sole [assessed by electromyogram
	jap.physiology.org /cgi/content/full/89/6/2344 (4651 words)

	Genome and Hormones: Gender Differences in Physiology: Selected Contribution: Gender differences in the endothelin-B ...
		Endothelin ET-A and ET-B receptors cause vasoconstriction of human resistance and capacitance vessels in vivo.
		Cutaneous active vasodilation in humans is mediated by cholinergic nerve co-transmission.
		Endothelin-A receptor antagonist-mediated vasodilation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade.
	jap.physiology.org /cgi/content/full/91/5/2407 (3615 words)

	Innate Immune Responses to Herpes Simplex Virus Type 2 Influence Skin Homing Molecule Expression by Memory CD4+ ...
		Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells.
		Expression of cutaneous lymphocyte-associated antigen regulated by a set of glycosyltransferases in human T cells: involvement of alpha1,3-fucosyl transferase VII and beta1,4-galactosyltransferase I. Investig.
		Chemokine receptor deficiency is associated with increased chemokine expression in the peripheral and central nervous systems and increased resistance to herpetic encephalitis.
	jvi.asm.org /cgi/content/full/80/6/2863 (6246 words)

	Sensory Structures
		Tonic receptors (slowly adapting) - maintain a constant rate of firing as long as a stimulus is maintained.
		includes cutaneous receptors (located in the skin) and proprioceptors.
		Proprioceptors are located in muscles, tendons, and joint capules and allow the brain to sense the position of the body parts (kinesthetic sense).
	www.dwu.edu /biology/Mullican/anaout15.htm (536 words)

	Lipoprotein-Dependent and -Independent Immune Responses to Spirochetal Infection -- Salazar et al. 12 (8): 949 -- ...
		Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides.
		The cutaneous response in humans to Treponema pallidum lipoprotein analogues involves cellular elements of both innate and adaptive immunity.
		Down-regulation of Toll-like receptor expression in monocyte-derived Langerhans cell-like cells: implications of low-responsiveness to bacterial components in the epidermal Langerhans cells.
	cvi.asm.org /cgi/content/full/12/8/949 (6321 words)

	A Newly Described, Rare Variant of Cutaneous T-Cell Lymphoma - Journal Watch Dermatology
		A Newly Described, Rare Variant of Cutaneous T-Cell Lymphoma
		The vast majority of cutaneous T-cell lymphomas are CD4+ lymphomas
		All 3 patients were men, ranging in age from 46 to 74, who presented
	dermatology.jwatch.org /cgi/content/full/2000/911/1 (279 words)

	Degree of CD25 Expression in T-Cell Lymphoma Is Dependent on Tissue Site: Implications for Targeted Therapy -- Jones et ...
		C, unlike cutaneous T-cell lymphoma, the benign dermatopathic infiltrate expands the interfollicular regions, leaving the follicular compartment intact.
		Wasik MA, Vonderheid EC, Bigler RD, et al Increased serum concentration of the soluble interleukin-2 receptor in cutaneous T-cell lymphoma.
		Abnormalities of circulating T-cell subpopulations in patients with cutaneous T-cell lymphoma: cutaneous lymphocyte-associated antigen expression on T cells correlates with extent of disease.
	clincancerres.aacrjournals.org /cgi/content/full/10/16/5587 (4447 words)

	Response Properties of Mechanoreceptors and Nociceptors in Mouse Glabrous Skin: An In Vivo Study -- Cain et al. 85 (4): ...
		of the capsaicin receptor (VR1) in mice on nociception (Caterina
		In conclusion, we have characterized response properties of mouse cutaneous receptors using an in vivo approach.
		Response of cutaneous sensoy units with unmyelinated fibers to noxious stimuli.
	jn.physiology.org /cgi/content/full/85/4/1561 (7280 words)

	Dictionary of Cancer Terms - National Cancer Institute
		The gene that controls cell growth by making the human epidermal growth factor receptor 2.
		A protein on the surface of some cells that binds to stem cell factor (a substance that causes certain types of cells to grow).
		Altered forms of this receptor may be associated with some types of cancer.
	www.nci.nih.gov /dictionary/db_alpha.aspx?expand=c (6049 words)

	Rapid Acquisition of Tissue-specific Homing Phenotypes by CD4+ T Cells Activated in Cutaneous or Mucosal Lymphoid ...
		of adhesion and chemoattractant receptors at distinct anatomical
		receptors may be upregulated stochastically in secondary lymphoid
		C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential.
	www.jem.org /cgi/content/full/195/1/135 (4655 words)

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