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Topic: Cystic medial necrosis

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Aneurysm

Aortic dissection

	eMedicine - Dissection, Aortic : Article Excerpt by: John Wiesenfarth, MD, MS, FACEP, FAAEM
		Cystic medial necrosis is the hallmark histologic change associated with dissection in those with Marfan syndrome.
		Cystic medial necrosis was first described by Erdheim in 1929.
		Early on, cystic medial necrosis described an accumulation of basophilic ground substance in the media with the formation of cystlike pools.
	www.emedicine.com /emerg/byname/dissection-aortic.htm (591 words)

	GE Healthcare - Brochure - Sonographic Evaluation of the Acute Abdomen
		Dissection of the aorta may be secondary to cystic medial necrosis or Marfan’s disease, or hypertension.
		The bacteria may reach the gallbladder via the blood stream or from the intestine by the common bile and cystic ducts or from the ulcerated duodenum either directly or by the portal vein.
		The most common cause of obstruction of the cystic duct is from a small gallstone that occludes the lumen of the duct.
	www.gehealthcare.com /usen/education/proff_leadership/products/msucmeaa.html (5277 words)

	Spartanburg SC \| GoUpstate.com \| Spartanburg Herald-Journal
		A degenerative breakdown of collagen, elastin, and smooth muscle caused by aging contribute to weakening of the wall of the artery.
		There is an association between cystic medial necrosis and Marfan syndrome.
		The term "cystic medial degeneration" is sometimes used instead of "cystic medial necrosis", because necrosis is not always found.
	www.goupstate.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=Cystic_medial_necrosis (142 words)

	Poly Cystic Ovaries (Site not responding. Last check: 2007-10-12)
		Cystic fibrosis 1: '''Cystic fibrosis''' ('''CF'''), also called '''mucoviscid 11: s recommended for families who may be carriers of cystic fibrosis.
		Cystic fibrosis transmembrane conductance regulator 1: '''Cystic fibrosis transmembrane conductance regulator''' (3: duce the abnormally thick mucus characteristic of cystic fibrosis.
		Cystic medial necrosis 1: '''Cystic medial necrosis''' is a disorder of large arter
	www.witchware.com /File/43078-Poly.Cystic.Ovaries.Html (654 words)

	Carotid artery aneurysm secondary to cystic medial necrosis
		Carotid artery aneurysm secondary to cystic medial necrosis is a rare clinical entity.
		The pathogenesis of carotid artery aneurysm secondary to cystic medial necrosis is discussed.
		In summary, cystic medial necrosis is a rare cause of isolated carotid artery aneurysm.
	www.rcsed.ac.uk /journal/vol46_3/4630010.htm (1103 words)

	Gsell-Erdheim syndrome (www.whonamedit.com)
		Cystic medial necrosis, medianecrosis aortae, medianecrosis aortae cystica idiopathica, medianecrosis aortae idiopathica, medianecrosis idiopathica aortae, medionecrosis idiopathica cystica.
		A historic term for idiopathic necrosis of the medial layer of the aorta with subsequent formation of cysts, without inflammatory changes, often leading to aortic rupture.
		Assumed to be a frequent cause of aneurisma dissecans aorta - aorta dissection, a dramatic sequence of aortic rupture.
	www.whonamedit.com /synd.cfm/2409.html (231 words)

	Arch Intern Med -- Abstract: Myxomatous degeneration and cystic medial necrosis associated with acromegaly, April 1, ...
		Arch Intern Med -- Abstract: Myxomatous degeneration and cystic medial necrosis associated with acromegaly, April 1, 1980, Ondreyco et al.
		to myxomatous degeneration and cystic medial necrosis of the aorta have
		cystic medial necrosis of the aorta and pulmonary artery.
	archinte.ama-assn.org /cgi/content/abstract/140/4/547 (132 words)

	Descending and Thoracoabdominal Aortic Aneurysms
		The etiology of thoracoabdominal aneurysms, in order of frequency, is medial degenerative disease (myxomatous or myxoid degeneration, senile aorta), dissection, Marfan syndrome (cystic medial necrosis), Ehlers-Danlos syndrome, infection (mycotic), aortitis (Takayasu's disease), and trauma (Table 41-1).
		The usual histologic changes of the aging aorta include cystic medial necrosis, elastin fragmentation, fibrosis with increased collagen, and medial necrosis.
		Body surface area is a better predictor of aortic size than height or weight and best correlates with aortic diameter in patients less than 50 years of age.
	www.ctsnet.org /edmunds/Chapter41section1.html (512 words)

	Medial degeneration
		Medial degeneration is a degenerative disorder in which elastic tissue and muscle fibres degenerate and various amounts of ground substance are deposited
		note that the now defunct term “cystic medial necrosis” is not used for medial degeneration as necrosis is not observed and the cysts are probably areas in which smooth muscle cells or elastic fibres once existed but have disappeared due to degeneration
		The best known clinical manifestation of medial degeneration is that which involves the ascending and transverse aortic arch causing anulo-aortic ectasia and aortic insufficiency.
	www.perfusion.com.au /CCP/Pathophysiology/Medial%20Degeneration.htm (286 words)

	Intracranial Aneurysms: Current Evidence and Clinical Practice - August 15, 2002 - American Family Physician
		Patients with fusiform aneurysms characteristically present with symptoms of cranial-nerve or brain-stem compression, but the symptoms are not commonly associated with subarachnoid hemorrhage.
		Dissecting aneurysms are the result of cystic medial necrosis or a traumatic tear of an artery.
		Like dissecting aneurysms elsewhere in the body (e.g., dissecting aortic aneurysms), they form as blood courses through a false lumen while the true lumen is collapsed upon itself.
	www.aafp.org /afp/20020815/601.html (3075 words)

	Cardiovascular Lab 1f
		Histologically, dissection is often associated with cystic medial necrosis.
		The term "cystic medial necrosis" is a misnomer, since no true cysts are formed, nor is there actual necrosis of tissue.
		The accumulation of this mucopolysaccharide material may be found to a mild degree in normal individuals.
	www.pathology.vcu.edu /education/cardio/lab1.f.html (142 words)

	Erdheim's cystic medial necrosis - General Practice Notebook (Site not responding. Last check: 2007-10-12)
		Cystic medial necrosis or degeneration is a disorder of large arteries, in particular the aorta, where there is a focal degeneration of the elastic tissue and the muscle in the media, with the presence of mucoid material in the media.
		It is more frequent after 40 years of age and is twice as common in males than in females.
		Oxbridge Solutions Ltd® is an independent company owned by the authors which does not receive income from any other organisation or individual.
	www.gpnotebook.com /cache/-1993015250.htm (134 words)

	Baylor Health Care System: Giant cell arteritis
		Other etiologies of aneurysm include cystic medial necrosis, syphilis, other bacterial infections, rheumatic aortitis, and trauma.
		Cystic medial necrosis involves degeneration of collagen and the elastic fibers, and then deposition of a mucoid material in the aortic media, as is seen in Marfan syndrome and in other conditions, such as pregnancy.
		Cystic medial necrosis also can be seen in systemic hypertension, which our patient has.
	www.baylorhealth.edu /proceedings/11_4/11_4_cpc.html (2541 words)

	Bilateral subclavian artery aneurysm associated with idiopathic cystic medial necrosis -- Fee et al. 26 (4): 387 -- The ...
		Bilateral subclavian artery aneurysm associated with idiopathic cystic medial necrosis -- Fee et al.
		Bilateral subclavian artery aneurysm associated with idiopathic cystic medial necrosis
		repair of a subclavian artery aneurysm secondary to cystic medial necrosis
	ats.ctsnetjournals.org /cgi/content/abstract/26/4/387 (229 words)

	Cardiovascular Case 4
		The aortic wall in most cases of aortic dissection is weakened by cystic medial necrosis.
		This low power micrograph shows a cross section of aorta with multiple areas of cystic medial necrosis.
		The areas of cystic medial necrosis can be recognized as zones in which the elastic laminae have been lost.
	omeweb2.ucdavis.edu /pmd/robbins/cvd4/cvd470.htm (73 words)

	Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, ...
		Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation -- Ihling et al.
		Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation
		Keywords: mucoid cystic medial degeneration of the aorta; p53 accumulation; apoptosis; cell proliferation
	www.heartjnl.com /cgi/content/full/82/3/286 (5133 words)

	[No title]
		Mediated by antibodies that cross-react with neurons (type II immune injury) Erythema marginatum, a snake-like red skin eruption Subcutaneous nodules, little masses of fibrinoid with granulomas around them, over the bony bumps on arms and legs.
		Cystic renal dysplasia: failure of drainage during intrauterine life, fibrous tissue, tubules, and cartilage.
		Causes of hypopituitarism: Sheehan's (necrosis of pituitary during post-partum shock), empty-sella syndromes, pituitary adenoma, surgery, radiation, trauma, rarely autoimmunity.
	www.pathguy.com /boildown.txt (11062 words)

	Spontaneous Dissection of Three Major Coronary Arteries Subsequent to Cystic Medial Necrosis -- Conraads et al. 116 ...
		Spontaneous Dissection of Three Major Coronary Arteries Subsequent to Cystic Medial Necrosis -- Conraads et al.
		coronary arteries due to severe cystic medial necrosis.
		Cystic medial necrosis of the coronary arteries is a rare finding,
	www.chestjournal.org /cgi/content/full/116/5/1473 (1422 words)

	Non-uniform aortic medial degenerative changes associated with aortic valve disease -- Veinot 22 (6): 1036 -- European ...
		medial disease (cystic medial necrosis), coarctation and congenital
		Agozzino L., Ferraraccio F., Esposito S., Trocciola A., Parente A., Della Corte A., De Feo M., Cotrufo M. Medial degeneration does not involve uniformly the whole ascending aorta: morphological, biochemical and clinical correlations.
		Roberts W.C. The congenitally bicuspid aortic valve: a study of 85 autopsy cases.
	ejcts.ctsnetjournals.org /cgi/content/full/22/6/1036-a (460 words)

	Angiotensin II Type 2 Receptor Mediates Vascular Smooth Muscle Cell Apoptosis in Cystic Medial Degeneration Associated ...
		Cystic medial degeneration (CMD) is a histological abnormality
		Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms.
		Apoptosis of medial smooth muscle cells in dilated ascending aortas of patients with Marfan’s syndrome and annulo-aortic ectasia.
	circ.ahajournals.org /cgi/content/full/104/suppl_1/I-282 (2748 words)

	[No title]
		Cardiovascular: cystic medial necrosis of the aorta, aortic incompetence, aortic dissection, aortic aneurysm, floppy mitral valve Ocular: subluxation of lenses Adult polycystic kidney disease is associated with what other diseases or disorders?
		(2) Pleural mesothelioma and bronchogenic carcinoma T/F Bronchiectasis is associated with bronchial obstruction, cystic fibrosis, and poor ciliary motility.
		Cystic Name the histologic type of fibrocystic breast disease: hyperplasia of breast stroma.
	umed.med.utah.edu /usmle/PDA/Pathology.txt (16095 words)

	Cystic articles, support groups, and resources
		Cystic mass in the Adnexal (Ovarian Cancer Forum)
		Is this Cystic Fibrosis, Asthma, or some other Pulmonary Disorder (Respiratory Disorders Forum)
		Solid and Cystic cysts of the ovaries (Ovarian Cancer Forum)
	www.medhelp.org /HealthTopics/Cystic.html (201 words)

	1996-1997 Annual Report (Site not responding. Last check: 2007-10-12)
		Cheng, Y., Sweetwood, J., Taylor, C., Roby, K.F., and Terranova, P.F. Proliferative and cytolytic effects of tumor necrosis factor alpha on mouse ovarian surface epithelial cells in vitro, XI Ovarian Workshop: Ovarian Cell Growth, Apoptosis and Cancer, July 24-26, 1996, London, Ontario, Canada.
		Summary of Research: My research focus is to test the hypothesis that EGF family of growth factors and their receptors could mediate the embryo/uterine interactions during early perimplantation period in mice.
		The studies are planned to investigate the role of G-protein mediated and tyrosine kinase-mediated signaling pathways in prostate tumor progression.
	www.kumc.edu /physiology/1996-7.htm (12706 words)

	Encyclopedia: Cystic medial necrosis
		People who viewed "Cystic medial necrosis" also viewed:
		Updated 233 days 15 hours 28 minutes ago.
		Cystic medial necrosis is a disorder of large arteries, in particular the aorta, where there is a focal degeneration of the elastic tissue and the muscle in the tunica media (the middle layer of the artery), with the presence of mucoid material in the media.
	www.nationmaster.com /encyclopedia/Cystic-medial-necrosis (146 words)

	Aneurysm (Site not responding. Last check: 2007-10-12)
		A dissecting aneurysm indicates a hemorrhagic separation in the aortic wall, usually within the medial layer.
		Other possible causes include cystic medial necrosis, trauma, syphilis, and infection.
		Femoral and popliteal aneurysms: Progressive atherosclerotic changes in the medial layer of the femoral and popliteal arteries may lead to aneurysm.
	www.med-help.net /Aneurysm.html (660 words)

	Aneurysm of the pulmonary artery with cystic medial necrosis and massive pulmonary valvular insufficiency. Report of ... (Site not responding. Last check: 2007-10-12)
		Aneurysm of the pulmonary artery with cystic medial necrosis and massive pulmonary valvular insufficiency.
		Institute of Cardiology, Department of Surgery, Abidjan, Ivory Coast.
		associated with pulmonary artery hypertension and showed cystic medial
	www.ejcts.ch /cgi/content/abstract/1/2/119 (172 words)

	THE MERCK MANUAL--SECOND HOME EDITION, Aneurysms in Ch. 35, Aneurysms and Aortic Dissection
		Thoracic aortic aneurysms are being identified more often than in the past because computed tomography (CT) of the chest to screen for other disorders is used more widely.
		In a common form of thoracic aortic aneurysm, the walls of the aorta degenerate (a condition called cystic medial necrosis), and the part of the aorta nearest the heart enlarges.
		This enlargement may cause a malfunction of the valve between the heart and the aorta (aortic valve), allowing blood to leak backward into the heart when the valve is closed.
	www.merck.com /pubs/mmanual_home2/sec03/ch035/ch035b.htm (2002 words)

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