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Topic: Cytolysis


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In the News (Tue 14 Feb 12)

  
  The Individualist: Cytolysis
Cytolysis is the lysis, or death, of cells due to the rupture of the cell membrane.
Cytolysis is caused by excessive osmosis, or movement of water, towards the inside of a cell.
In a hypertonic environment, plasmolysis occurs, which is nearly the complete opposite of cytolysis: Instead of expanding, the cytoplasm of the plant cell retracts from the cell wall, causing the plant to wilt.
www.dadamo.com /wiki/wiki.pl/Cytolysis   (531 words)

  
  NationMaster - Encyclopedia: Cytolysis
Cytolysis is the lysis, or death, of cells due to the rupture of the cell membrane.
Cytolysis in the absence versus that in the presence of 1 µg/mL MEM48 was P =.0052.
Cytolysis in the absence versus that in the presence of D-mannose was P =.028.
www.nationmaster.com /encyclopedia/Cytolysis   (1024 words)

  
 Spartanburg SC | GoUpstate.com | Spartanburg Herald-Journal   (Site not responding. Last check: 2007-09-17)
Cytolysis is the lysis of cells in a hypotonic environment.
Cytolysis is caused by excessive osmosis, or movement of water, towards the inside of a cell (hyperhydration).
Cytolysis can be prevented by several different mechanisms, including the contractile vacuole that exists in some paramecium which rapidly pump water out of the system of the cell.
www.goupstate.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=lysis   (315 words)

  
 ANNALS Feb2003: CYTOLYSIS OF EOSINOPHILS IN NASAL SECRETIONS   (Site not responding. Last check: 2007-09-17)
Currently, cytolysis is being reevaluated as the mode of degranulation of eosinophils in allergic nasal mucosa.
To examine whether eosinophils migrating to the nasal mucus degranulate by cytolysis, we sampled nasal mucus from 9 patients with nasal allergy and observed it under electron and light microscopes.
We concluded that eosinophils migrating to the nasal mucus degranulate mainly by cytolysis, and that granular proteins released from the necrotic eosinophils into the nasal mucus are one of the important factors causing hypersensitivity in the nasal mucosa.
www.annals.com /abs/annals1157.htm   (191 words)

  
 Respiratory Research | Full text | Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates ...
Eosinophil cytolysis causing extra-cellular spilling of eosinophil granules commonly occurs in asthmatic bronchi [13] but it is not known whether stimulation of the Fas-receptor may evoke cytolysis of eosinophils.
Eosinophil cytolysis, which emerges as a major mode of eosinophil degranulation in asthma and rhinitis is characterized by chromatolysis of the cell nucleus and rupture of the cell membrane, whereby the protein-rich specific eosinophil granules are released into the tissue [29].
Cytolysis has not previously been observed in mouse airway tissue eosinophils [34], but is of particular interest because this mode of degranulation is prominent in human airway eosinophilic diseases [29,35].
www.respiratory-research.com /render/render.asp?vol=6&iss=1&page=90&type=&item=&pubtype=content&   (5442 words)

  
 MedFriendly.com: Cytolysis
Cytolysis is the breakdown or destruction of cells.
In cytolysis, it is usually the cell membrane that is destroyed.
Cytolysis comes from the Greek word "kytos" meaning "a hollow cell," and the Greek word "lysis" meaning "loosening." Put the two words together and you have "loosening (of) a hollow cell."
www.medfriendly.com /cytolysis.html   (143 words)

  
 Cytolysis - Qwika
Cytolysis Cytolysis is the lysis, or death, of cells...
Cytolysis is caused by excessive osmosis, or movement...
of one anemy haemolytic, of one hepatic cytolysis and of one thrombopénie at a pregnant...
www.qwika.com /find/Cytolysis   (343 words)

  
 Cytolysis by Tumor Necrosis Factor is Preceded by a Rapid and Specific Dissolution of Microfilaments -- Scanlon et al. ...
Cytolysis by Tumor Necrosis Factor is Preceded by a Rapid and Specific Dissolution of Microfilaments -- Scanlon et al.
Cytolysis by Tumor Necrosis Factor is Preceded by a Rapid and Specific Dissolution of Microfilaments
In this report, we examine the mechanism of cytolysis in a 3T3-like mouse cell line, C3HA, which was sensitized to TNF by treatment with CHI.
www.pnas.org /cgi/content/short/86/1/182   (412 words)

  
 Infotrieve Online
We have investigated the detachment and cytolysis of 51Cr-labeled umbilical vein endothelial cells (HUVEC) induced by highly purified, enzymatically active, PR3 and elastase.
Elastase was responsible for 60% of the detachment and 19% of the cytolysis.
PR3-mediated cytolysis was inhibited by each of the c-ANCA+IgG preparations and also to a limited extent by control IgG, suggesting a partial nonspecific stabilization of the endothelial cells.
www4.infotrieve.com /newmedline/detail.asp?NameID=7805749&Session=&searchQuery=Klar%2DMohamad&count=18   (294 words)

  
 Cytolysis - Wikipedia, the free encyclopedia
Cytolysis, or osmotic lysis, occurs when a cell bursts due to an osmotic imbalance that has caused excess water to move into the cell.
Different cells and organisms have adapted different ways of preventing cytolysis from occurring.
If the cell can pump out enough solutes so that an isotonic environment can be achieved, there will be no net movement of water.
en.wikipedia.org /wiki/Cytolysis   (347 words)

  
 Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease ...
Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease Inhibitor-Containing Antiretroviral Regimen in Human Immunodeficiency Virus-Infected Patients -- Savès et al.
The first cases of severe cytolysis were described in patients receiving IDV only (2, 10, 13, 19).
of the pathophysiology of acute cytolysis in antiretroviral-treated
aac.asm.org /cgi/content/full/44/12/3451   (2836 words)

  
 NCI Bethesda System 2001
Abundant lactobacilli with intermediate squamous cells, many of which show cytolysis (bare nuclei with partial or complete stripping of cytoplasm).
In determining specimen adequacy, nuclear preservation and visualization are of key importance, and changes such as cytolysis and partial obscuring of cytoplasmic detail may not necessarily interfere with specimen evaluation.
Abundant cytolysis(>~50%) may be mentioned as a quality indicator, but most such specimens do not qualify as unsatisfactory unless nearly all of the nuclei are devoid of cytoplasm.
www.cytopathology.org /NIH/view.php?patientId=324   (96 words)

  
 Protease Inhibitor Use & ALT Elevations
After a mean follow-up of 5 months, severe cytolysis developed in 23 patients, yielding an incidence of 5 per 100 patient-years (95% confidence interval, 3.2 to 7.6).
At the onset of severe cytolysis, two patients were receiving saquinavir (SQV), five patients were receiving ritonavir (RTV), seven patients were receiving indinavir (IDV), five patients were receiving nelfinavir (NFV), one patient was receiving SQV and RTV, one patient was receiving IDV and NFV, and one patient was receiving RTV and NFV.
The initially prescribed PIs were stopped after the occurrence of severe cytolysis in 17 other patients, among whom 6 were switched to another PI and 1 was switched to nevirapine.
www.natap.org /2000/dec/protease_inhib120800.htm   (1226 words)

  
 Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate -- Wolberg et ...   (Site not responding. Last check: 2007-09-17)
The in vitro destruction of tumor cells by specifically sensitized mouse lymphocytes was inhibited by adenosine; this inhibition was markedly potentiated by the presence of an inhibitor of adenosine deaminase.
The inhibition of cytolysis by adenosine was accompanied by a rapid elevation in lymphocytic adenosine 3',5'-monophosphate (cyclic AMP) concentrations.
Both the inhibition of cytolysis and the elevation of cyclic AMP were reversed by prolonged incubation of the lymphocytes in the presence of adenosine or, more rapidly, by removal of the adenosine.
www.sciencemag.org /cgi/content/abstract/187/4180/957   (543 words)

  
 Unbound MEDLINE | Monochloramine-induced cytolysis to cultured rat gastric mucosal cells: role of glutathione and iron ...
Monochloramine-induced cytolysis to cultured rat gastric mucosal cells: role of glutathione and iron in protection and injury.
To clarify mechanisms by which NH2Cl induces cytolysis, we determined the effects of glutathione (GSH) alteration and iron chelation on NH2Cl-induced damage in cultured rat gastric mucosal cells, because these are involved in oxidant injury.
However, the mechanisms of NH2Cl-induced damage seem to be distinctly different from cytolysis by H2O2 in terms of the mediation of cellular iron.
www.unboundmedicine.com /medline/ebm/record/10521083/abstract/Monochloramine_induced_cytolysis_to_cultured_rat_gastric_mucosal_cells:_role_of_glutathione_and_iron_in_protection_and_injury   (300 words)

  
 New Aspects of Degranulation and Fates of Airway Mucosal Eosinophils -- ERJEFÄLT and PERSSON 161 (6): 2074 -- ...
Eosinophils may be stimulated in vitro to undergo cytolysis (a) or apoptosis (b).
symptoms of allergic rhinitis, the occurrence of eosinophil cytolysis
cytolysis is a potent proinflammatory mechanism, and that the
ajrccm.atsjournals.org /cgi/content/full/161/6/2074   (6248 words)

  
 Interaction of an Adenovirus E3 14.7-Kilodalton Protein with a Novel Tumor Necrosis Factor Alpha-Inducible Cellular ...
not reverse the E3-14.7K inhibition of TR55 cytolysis (Fig.
A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor.
The adenovirus E3 14.7K protein, an antagonist of tumor necrosis factor cytolysis, increases the virulence of vaccinia virus in SCID mice.
mcb.asm.org /cgi/content/full/18/3/1601   (5935 words)

  
 Comparative Hepatology | Abstract | MHC class I expression protects rat colon carcinoma cells from hepatic natural ...
Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like colon carcinoma cells.
It is known that major histocompatibility complex (MHC) class I on tumour cells negatively regulates NK cell-mediated cytolysis, but this is found using blood- or spleen-derived NK cells.
Therefore, using isolated rat hepatic NK cells and the syngeneic colon carcinoma cell line CC531s, we investigated whether this protective role of MHC class I is also operative in hepatic NK cells, and addressed the mechanism of MHC class I protection.
www.comparative-hepatology.com /content/1/1/2/abstract   (339 words)

  
 Effective osteosarcoma cytolysis using cytokine-induced killer cells pre-inoculated with tumor RNA-pulsed dendritic ...
Effective osteosarcoma cytolysis using cytokine-induced killer cells pre-inoculated with tumor RNA-pulsed dendritic cells.
In addition to the observed CIK cell-induced osteosarcoma cytolysis, the pre-incubation of CIK cells with autologous dendritic cells pulsed with tumor's total RNA further enhanced the tumor cytolysis to greater than 6-fold.
The anti-tumor cytolysis was optimized in complete autologous setting, and was attenuated with allogeneic components.
bonecancer.researchtoday.net /archive/2/10/600.htm   (297 words)

  
 Protease inhibitors associated with hepatic cytolysis
Severe cytolysis developed in 23 patients, including 16 infected with hepatitis C and 5 infected with hepatitis B, the investigators report.
In multivariate analysis, positivity for hepatitis C antibodies was associated with a hazard ratio of 7.95, and positivity for hepatitis B surface antigen with a hazard ratio of 6.67.
The investigators observed "no association between severe cytolysis and the type of protease inhibitor or the response at month 1 in terms of CD4+ cell count and plasma HIV RNA level."
www.aidsmeds.com /news/20001205epid002.html   (360 words)

  
 MEDLINE_1966-1995 - Resultado de la búsqueda <página 1>
Cytolysis of the L929 target occurred when it was cocultured with BCG-activated macrophages even when these effector cells did not secrete TNF, either due to prior chemical crosslinking or to lack of exposure to a triggering level of lipopolysaccharide.
Furthermore, by introduction of the anti-TNF antiserum over a dose-range, it was shown that macrophage cytolysis both of L929 and EMT-6 targets occurred in the absence of bioavailable, fluid-phase TNF.
Thus, even for targets susceptible to fluid-phase TNF, TNF-dependent, direct macrophage-mediated cytolysis appears to be a function independent of secreted TNF and one that utilizes effector-target contact to express the action of a membrane form of the molecule.
www.bireme.br /cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE_1966-1995&exprSearch=2167918&indexSearch=UI&lang=e   (282 words)

  
 NIH Office of Technology Transfer (OTT) >> Abstract Search   (Site not responding. Last check: 2007-09-17)
Therapeutic uses of ultrasound (e.g., sonoporation, thrombolysis, HIFU, sonophoresis, acoustic hemostasis) may induce changes in tissue state, including apoptosis and cytolysis, through thermal effects (e.g., hyperthermia), mechanical effects (e.g., acoustic cavitation or through radiation force, acoustic streaming and other ultrasound induced forces), and chemical effects (via sonochemistry or by the activation of solutes by sonoluminescence).
ultrasound bioreactors, are limited by the need to decrease cytolysis of microbes or animal and plant cells.
Accordingly, the protecting molecules used to carry out the methods of the invention possess the ability to protect cells against ultrasound mediated cytolysis, without hindering ultrasound induced physical effects that could be utilized to create beneficial effects.
ott.od.nih.gov /db/abstxt.asp?refno=1177   (231 words)

  
 Respiratory Research | Abstract | Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates ...
We thus hypothesized that effects of anti-Fas mAb in vivo may include both apoptosis and cytolysis of eosinophils and, hence, that established eosinophilic inflammation may not resolve by this treatment.
Anti-Fas mAb evoked apoptosis of 28% and cytolysis of 4% of eosinophils present in allergen-challenged airway tissues.
This outcome may partly reflect the ability of anti-Fas to evoke direct cytolysis of non-apoptotic eosinophils in airway tissues.
www.respiratory-research.com /render/render.asp?vol=6&iss=1&page=90&type=abstract&item=&pubtype=content&   (382 words)

  
 Dept. of Immunology, Gideon Berke Complete Publications
Stulting, R.D. and Berke, G. The use of 51Cr release as a measure of lymphocyte-mediated cytolysis in vitro.
Fishelson, Z. and Berke, G. T lymphocyte-mediated cytolysis: Dissociation of the binding and lytic mechanisms of the effector cell.
Berke, G. Lymphocyte-mediated Cytolysis: Effectors, lytic signals and the mechanism whereby early membrane derangements result in target cell death.
www.weizmann.ac.il /immunology/BerkePuball.html   (3320 words)

  
 Decreased apoptosis and sensitivity to macrophage mediated cytolysis of endometrial cells in endometriosis -- Dmowski ...
Decreased apoptosis and sensitivity to macrophage mediated cytolysis of endometrial cells in endometriosis -- Dmowski et al.
Decreased apoptosis and sensitivity to macrophage mediated cytolysis of endometrial cells in endometriosis
the capacity of monocytes to mediate cytolysis of the misplaced
humupd.oxfordjournals.org /cgi/content/abstract/4/5/696   (551 words)

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