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| | The Scientist : How oxygen changed metabolism (Site not responding. Last check: 2007-11-02) |
 | | Previous work by first author Jason Raymond of Lawrence Livermore National Laboratory in California revealed that, in aerobic organisms, many anoxic enzymatic reactions were replaced with new reactions and enzymes. |
| | Still, Raymond and Segrè’s approach “has one serious shortcoming,” according to Wagner -- in many of the sampled genomes, enzymatic reactions are inferred based on sequence similarity to known enzymes in another organism. |
| | Raymond, D. Segrè, “The effect of oxygen on biochemical networks and the evolution of complex life,” Science, March 24, 2006. |
| www.the-scientist.com /news/display/23245 (879 words) |
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