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Topic: Decompensation

	Risk factors for hepatic decompensation in patients with HIV/HCV coinfection and liver cirrhosis during ...
		The incidence of hepatic decompensation in this cirrhotic subgroup (14/134) was 10.4%.
		Decompensation in the remaining patient after 24 weeks was felt to reflect natural progression of liver disease and was excluded from the analysis..
		The early occurrence of hepatic decompensation in the course of interferon-based therapy suggests the possibility of a direct treatment effect such as hepatotoxicity or immune activation resulting in the clearance of HCV-infected liver cells.
	www.natap.org /2004/HCV/081904_03.htm (1710 words)

	Decompensation and Failure to Thrive in Wilderness Programs
		Decompensation and the failure of students to thrive in a wilderness program is a real but very infrequent event.
		Decompensation and a failure to thrive are more severe problems and very different problems than the failure of a student to benefit from a particular program.
		Decompensation and failure to thrive are usually the result of one or two of the following factors.
	www.oregoncounseling.org /Wilderness/Decompensation.htm (1056 words)

	Coronal Plane Trunk Shifts and Decompensational Perspectives in a New Design of an Asymmetrical TLSO Module - Journal ...
		Figure 3 depicts the proposed action of the shift in an asymmetrical orthosis from a scoliosis pattern of two curves, both being on the same side of the CSL because of the trunk shift created by the lumbar curve.
		Trunk shift in Patient 3 (Table 3 and Figure 10) was attempted because of a lack of a favorable response from axillary and trocanteric forces applied to the spine in her symmetrical module on the coronal plane.
		As is evident in Tables 1 to 6, a marked decrease in trunk shift and decompensation was achieved with the use of the shifting principle.
	www.oandp.org /jpo/library/2004_01_016.asp (3785 words)

	Decompensation And Failure to Thrive In Wilderness Therapy And Intervention Programs.
		Decompensation and the failure of students to thrive in a wilderness program are actual, yet very infrequent events.
		Decompensation is a more severe, and very different problem than the failure of a student to benefit from a particular program.
		Decompensation and failure to thrive are usually the result of one or both of the factors described below.
	www.strugglingteens.com /mconnorart/decompensate.html (1011 words)

	Decompensation - Wikipedia, the free encyclopedia
		In physiology, decompensation is the failure of the heart to maintain adequate blood circulation, marked by labored breathing, engorged blood vessels, and edema.
		Decompensation is also the decomposition of mental healthiness, whereby one who suffers from a mental illness falls into a decreasing ability to think and carry on daily activiites.
		The terminology is often used by personnel in psychiatric facilities to refer to patients who are having a severe manic episode following a relative period of normality.
	en.wikipedia.org /wiki/Decompensation (173 words)

	Hepatitis Central, Determinants of Outcome of Compensated Hepatitis C Virus-Related Cirrhosis, Current Information On ...
		The aim of this study was to assess the incidence of decompensation (ascites, jaundice, variceal bleeding, and encephalopathy), hepatocellular carcinoma (HCC) and death or liver transplantation in patients with compensated hepatitis C virus (HCV)-related cirrhosis, taking into account the viral genotype and interferon (IFN) therapy.
		Decompensation was considered to be related to HCC if decompensation and HCC were diagnosed at the same time.
		The probability of decompensation which was not related to HCC was quite high, 15% and 20% at 2 and 4 years, respectively.
	www.hepatitis-central.com /hcv/info/outcome/compensated.html (3345 words)

	HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis
		In other studies in which the survival of decompensated cirrhosis was assessed, HCC was not included as a type of decompensation.[25][26] This fact might have led to a reduction in the survival of the patients included in this survey.
		HE as the first decompensation has also been found previously to have a strong impact on the survival of patients with cirrhosis,[29][30] including those harboring HCV-related cirrhosis.[25] In our study, HE was associated with a poorer outcome independently of the number of simultaneous events patients presented.
		The event that led the patient to the hospital was considered as the type of the first hepatic decompensation in the analysis.
	www.natap.org /2005/HCV/040905_03.htm (3666 words)

	Sound off: Where the views and opinions of our staff and others are expressed on various topics that relate to Bush
		The folks with medical training who read me are probably going to wince at the over-simplification, but decompensation means reality tears apart the delusions, and the person holding the delusions proceeds to become unstuck.
		With a patient who has decompensated, you put him in a safe, cloistered environment, where stimulus is kept very low key, and you attempt to reassert as much of his previous perception of life as is practicable.
		The trouble with decompensation is that if the afflicted had a pathological personality before it happened, it will become far worse during and immediately after.
	www.topplebush.com /oped2124.shtml (1922 words)

	AASLD: Over-the-counter Analgesics Appear to Have Little Impact on Worsening Condition of Cirrhosis Patients (Site not responding. Last check: 2007-11-03)
		The researchers found that 19% of the patients hospitalised for cirrhotic decompensation used acetaminophen in the past 30 days compared to 26% of non-decompensated cirrhotics and 42% of non-cirrhotic controls.
		It was also found that 15% of the patients hospitalized for cirrhotic decompensation used NSAIDs in the past 30 days compared with 31% of non-decompensated cirrhotics and 34% of non-cirrhotic controls.
		Among patients hospitalised for cirrhotic decompensation, an average of 532 grams of alcohol was consumed in the past 30 days compared with 60 grams consumed on average among non-decompensated cirrhotics and 28 grams of alcohol consumed on average by the non-cirrhotic controls.
	www.pslgroup.com /dg/23de7e.htm (723 words)

	Delayed Response to Decompensation
		Webber's psychiatrist to his several-day period of decompensation, his elopement the evening before, and his planned return to the residence that morning.
		Webber eloped that evening, drove to his father's home, and refused to return for medications, staff made no attempt to bring him his medications, visit and assess his situation with his father, or call clinicians for assistance in assessing and responding to the entire scenario: Mr.
		Webber's nine-day period of decompensation, his report of this being a "difficult time" due to the anniversaries of family members' deaths, and the unusual events of that day, i.e., his elopement, driving in the dark, and wanting to stay with his mentally disabled father.
	www.cqc.state.ny.us /could_this_happen/case7.htm (1472 words)

	eMedicine - Heart Failure : Article by Michael E Zevitz, MD
		In patients with CHF, the risk of cardiac sudden death from ventricular tachycardia (VT) or ventricular fibrillation is considerable, and the degree of risk is correlated with the degree of decompensation and the degree of LV dysfunction.
		Alternatively, decompensation may occur as a result of failure or exhaustion of the compensatory mechanisms but without any change in the load on the heart in patients with persistent severe pressure or volume overload.
		Inappropriate reduction of therapy: The most common cause of decompensation in a previously compensated patient with heart failure is inappropriate reduction in the intensity of treatment, whether dietary sodium restriction, physical activity reduction, drug regimen reduction, or, most commonly, a combination of these measures.
	www.emedicine.com /med/topic3552.htm (11200 words)

	Corneal Decompensation After Intraocular Ophthalmic Surgery -- Missouri, 1998
		A case was defined as corneal endothelial decompensation within 24 hours after surgery in any patient undergoing intraocular ophthalmic surgery during January 5-14, 1998.
		To ascertain cases and to determine the background rate of corneal decompensation, medical records of patients undergoing ophthalmic surgery during September 1997-January 1998 were reviewed.
		When case-patients were compared with six randomly selected controls who underwent surgery during January 5-14 and did not have corneal decompensation, there were no differences in type of ophthalmic surgery performed; medications used before, during, or after surgery; type of local or general anesthesia; surgeons or anesthesiologists; or scrub and circulating nurses.
	www.cdc.gov /mmwr/preview/mmwrhtml/00052237.htm (1233 words)

	DECOMPENSATION
		Failure of compensation; cardiac decompensation is marked by dyspnea, venous engorgement, and edema.
		"DECOMPENSATION" is used about 15 times out of a sample of 100 million words spoken or written in English.
		All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.
	www.websters-online-dictionary.org /definition/english/De/Decompensation.html (289 words)

	12.00-Mental Disorders-Adult
		Episodes of decompensation are exacerbations or temporary increases in symptoms or signs accompanied by a loss of adaptive functioning, as manifested by difficulties in performing activities of daily living, maintaining social relationships, or maintaining concentration, persistence, or pace.
		Episodes of decompensation may be demonstrated by an exacerbation in symptoms or signs that would ordinarily require increased treatment or a less stressful situation (or a combination of the two).
		If you have experienced more frequent episodes of shorter duration or less frequent episodes of longer duration, we must use judgment to determine if the duration and functional effects of the episodes are of equal severity and may be used to substitute for the listed finding in a determination of equivalence.
	www.ssa.gov /disability/professionals/bluebook/12.00-MentalDisorders-Adult.htm (6098 words)

	Mental Help Net - Glossary Item Detail
		To 'decompensate' means (more or less) to fall apart mentally and emotionally.
		Decompensation occurs during the onset of a psychotic process.
		Other (non-psychotic) persons may decompensate when the stressors they are faced with are greater than their coping abilities can manage.
	www.mentalhelp.net /poc/view_index.php?idx=37&id=138 (52 words)

	: DI 22511.005 - Documenting the Impact of a Medically Determinable Mental Impairment on an Individual’s Ability to ... (Site not responding. Last check: 2007-11-03)
		Deterioration or decompensation in work or work-like settings (i.e., the B4 criterion) refers to failure to adapt to stressful circumstances which cause the individual either to withdraw from that situation or to experience exacerbation of signs and symptoms or experience deterioration in previously attained adaptive skills.
		For the B3 criterion (deficiencies in concentration, persistence, or pace) and B4 criterion (episodes of deterioration or decompensation), documentation must be sufficient to permit an assessment of their frequency, duration, and effect on the claimant's function.
		Concerning repeated episodes of deterioration or decompensation, this criterion is satisfied only if the episodes are substantially as described for the “B4” criterion, or if the residual disease process has resulted in such marginal adjustment that any increase in mental demands or change in the environment would be predicted to cause such deterioration or decompensation.
	policy.ssa.gov /poms.NSF/lnx/0422511005 (1642 words)

	Increased liver decompensation risk with atypical hepatitis C virus antibody levels.
		Knowledge of serum markers of liver decompensation would facilitate care of patients with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections.
		In multivariate analysis, decompensation was associated with high anti-c100(p) titer (>/=1:4050; odds ratio [OR], 3.
		With high anti-c100(p) or low anti-c22(p), sensitivity for decompensation was 86%-96% and specificity was 21%-36%; with both markers, sensitivity was 29%-32% and specificity was 93%-96%.
	www.aegis.com /aidsline/2000/dec/A00C0801.html (417 words)

	Lamivudine Reduced Risk of Hepatic Decompensation & Liver Cancer by Half
		The primary end point was time to disease progression, defined by hepatic decompensation, hepatocellular carcinoma, spontaneous bacterial peritonitis, bleeding gastroesophageal varices, or death related to liver disease.
		Conclusions: Continuous treatment with lamivudine delays clinical progression in patients with chronic hepatitis B and advanced fibrosis or cirrhosis by significantly reducing the incidence of hepatic decompensation and the risk of hepatocellular carcinoma.
		Chronic hepatitis B is a highly variable disease in which factors such as the age of the patient, the duration of infection, the immune response of the host, and the viral genotype influence the activity, rate of progression, and severity of liver disease.
	www.natap.org /2004/HBV/100804_01.htm (3047 words)

	Rare Pediatric Disease Database (Site not responding. Last check: 2007-11-03)
		High protein diets, constipation, and infections usually trigger recurrent episodes of metabolic decompensation and these recurrent episodes are usually separated by periods of normal health.
		Metabolic decompensation leads to admission to the hospital where children are started on intravenous fluids and not allowed to eat.
		During an acute episode of metabolic decompensation, patients are admitted to the hospital for intravenous hydration and management of any associated complications.
	www.madisonsfoundation.org /content/3/1/display.asp?did=278 (780 words)

	Cancer and Wisdom of the Body: New Medicine and aging
		During decompensation WOB has to handle also the ensuing diseases, as described in the chapters on diabetes mellitus, and Parkinson's disease
		The physician's role is to slow down the decline of physiological functions (linear aging), and so delay the onset of decompensation (accelerated aging).
		Any decompensation is still the most optimal WOB solution in circumstances.
	www.what-is-cancer.com /papers/newmedicine/slowdownaging.html (2344 words)

	POST POLIO SYNDROME
		This mode of decompensation augured by fatigue, may be anterior horn cell based.
		Another mode of decompensation is muscle fiber based: Rapidly firing muscle fibers produce more lactic acid which may not be adequately dissipated.
		Decompensation may be caused by even slight embarrassment in strength due to inactivity or injury superimposed upon aging.
	www.plee.com /pps/ppspamph.htm (3236 words)

	Aidsmap \| Hepatic decompensation risk factors in APRICOT study reported
		Advanced cirrhosis and concurrent treatment with ddI (didanosine) are the key risk factors for the development of decompensated cirrhosis (a marked and sometimes irreversible decline in liver function) during treatment of hepatitis C with pegylated interferon and ribavirin, according to an analysis of the APRICOT study published in the September 3
		Thirteen of fourteen hepatic decompensations happened during the first twenty-four weeks of treatment and were considered related to treatment.
		Six deaths were attributed to hepatic decompensation, while four of the eight remaining cases had resolved by week 78.
	www.aidsmap.com /en/news/B02AB236-5C09-47CC-895D-0E58FADE4B79.asp (680 words)

	Glasgow - 2002[PL12-4] Risk factors for hepatic decompensation in cirrhotic patients with HIV-HCV coinfection treated ...
		Variables associated with hepatic decompensation in univariate analysis were: higher total bilirubin and alkaline phosphatase; lower albumin, hemoglobin and platelets; and didanosine treatment (p<0.05).
		The majority of risk factors associated with hepatic decompensation, however, are biological markers for advanced cirrhosis.
		Therefore, patients with early stage cirrhosis may not be at high risk of decompensation and should be considered for HCV treatment.
	www.aegis.com /conferences/hiv-glasgow/2002/PL12-4.html (342 words)

	Risk Factors for Hepatic Decompensation in Patients with HIV-HCV Coinfection and Liver Cirrhosis During ... (Site not responding. Last check: 2007-11-03)
		Hepatic decompensation was reported from two recent trials (APRICOT and RIBAVIC) assessing interferon (IFN)-based treatment of hepatitis C virus (HCV) in HIV-HCV-coinfected patients.
		APRICOT is a randomized, partially-blinded, controlled trial comparing treatment with peg-IFN [alfa]-2a (Pegasys) 180 [mu]g once weekly plus ribavirin/placebo 400 mg twice daily with IFN [alfa]-2a (Roferon A) 3 million units three times weekly plus ribavirin 400 mg twice daily for 48 weeks in a total of 859 patients.
		The risk factors associated with hepatic decompensation were increased bilirubin, decreased haemoglobin, increased alkaline phosphatase or decreased platelets, and treatment with didanosine (ddI; Videx).
	www.hivandhepatitis.com /hiv_hcv_co_inf/082704_a.html (445 words)

	101. Jahrestagung der DOG, 25. - 28. 9. 2003 - Allgemeine Informationen (Site not responding. Last check: 2007-11-03)
		He presented with visual loss to hand movements in addition to corneal as well as tensio decompensation on his better right eye.
		No signs of inflammation were detected; the corneal transplant remained unaffected and ocular tension regular.
		Conclusions: Even big cysts with subsequent corneal decompensation can be treated with mere sector iridectomy avoiding wide en-bloc excision of surrounding ocular tissue.
	www.dog.org /2003/abstracts/336_e.html (903 words)

	AEGiS-TAG: Battleground: Schering and Roche Duke It Out Over the Huge Hepatitis C Market As Concerns Arise for Some ...
		Among the seven patients, three patients were enrolled by investigators even though they violated the protocol entry criteria; two patients had Child's class B and one had previous splenectomy...All three of these patients who violated entry criteria had further progression of hepatic decompensation and later died.
		Study personnel should be educated on the importance of careful assessment for evidence of hepatic decompensation in co-infected patients with cirrhosis who are being treated with antiretroviral therapy, especially at baseline, but also throughout therapy, particularly within the first 16 weeks.
		Patients with evidence of hepatic decompensation should be withdrawn from therapy immediately and carefully followed until they recover completely.
	www.aegis.com /pubs/tag/2001/TG011002.html (1668 words)

	Scheda Pubblicazione (Site not responding. Last check: 2007-11-03)
		During follow-up HCC developed in 32 (9%) of the 349 patients and decompensation was observed in 88 (28%) of 317 tumor-free patients.
		Five years after diagnosis, the probability of HCC appearance was 6% and the probability of decompensation was 23%.
		After the first episode of decompensation the probability of survival was 35% at 5 years.
	centri.univr.it /ricerca/pubblica.asp?Azione=VediScheda&IDPubblicazione=3201&Tipo=Rivista (304 words)

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