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Topic: Deep brain stimulation

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In the News (Tue 20 Aug 19)

  Deep Brain Stimulation
Deep brain stimulation (DBS) in adults is a one- or two-stage procedure under both local and general anesthesia.
Deep brain stimulation does not usually improve the "on" state (the patients best condition), but hopes to improve the patient when they are in their worst state.
The stimulators can be programmed in many different ways (the voltage, the frequency with which the stimulus is delivered to the brain, the length of each stimulus, and the shape of the stimulus and region that it influences the brain cells) and each patient may be different.
www.neurosurgery.pitt.edu /imageguided/movement/stimulation.html   (1652 words)

 What is DBS?
Deep brain stimulation (DBS) is a way to inactivate the thalamus, the subthalamic nucleus, or globus pallidus without purposefully destroying the brain.
Deep brain stimulation of the subthalamic nucleus is effective for all major symptoms of Parkinson's disease, such as tremor, slowness of movement, rigidity, and problems with walking and balance.
Deep brain stimulation of the globus pallidus is effective for a wide range of Parkinson's symptoms.
www.clevelandclinicmeded.com /deepbrainpatient/whatisdbs.htm   (711 words)

 Deep Brain Stimulation for Parkinson's Disease
Deep brain stimulation of the subthalamic nucleus is a procedure in which tiny electrodes are placed via computer guidance and physiological mapping into the subthalamic nucleus on each side of the brain.
Electrical stimulation of the subthalamic nucleus effectively jams or blocks the abnormal circuitry of the brain in Parkinson’s disease, thus minimizing many of the disabling symptoms and improving the overall quality of life of patients suffering from this degenerative disease.
Reduction of the amount of dopamine in the brain interferes with the normal brain circuitry involved in movement; in particular, areas of the brain known as the basal ganglia, thalamus, subthalamic nucleus and motor cortex.
www.northshorelij.com /body.cfm?id=3751   (247 words)

 Medical College of Wisconsin - Deep Brain Stimulation   (Site not responding. Last check: 2007-11-04)
Deep Brain Stimulation (DBS) is a surgical option for patients with Parkinson's disease, Essential Tremor, dystonia, and other movement disorders that are not responding to the usual medications, or where those medications are causing unwanted side-effects.
Deep brain stimulation is a new and improved variation of an old surgery.
Deep brain stimulation involves the implantation of a very thin lead containing four electrode contacts into a specific target area in the brain.
www.mcw.edu /display/router.asp?docid=13534   (1060 words)

 From the Cleveland Clinic: Surgical Treatments: Deep Brain Stimulation
Deep brain stimulation is a way to inactivate parts of the brain that cause Parkinsons disease and its associated symptoms without purposefully destroying the brain.
In deep brain stimulation electrodes are connected by wires to a type of pacemaker device (called an impulse generator, or IPG) implanted under the skin of the chest, below the collarbone.
Consequently, deep brain stimulation of the thalamus is usually not performed for patients with Parkinson's disease.
www.webmd.com /content/article/46/1833_50743.htm   (1797 words)

 Deep Brain Stimulation on MedicineNet.com
Deep brain stimulation is a way to inactivate the parts of the brain that cause Parkinsons, the thalamus or globus pallidus, without purposefully destroying the brain.
In deep brain stimulation, electrodes are placed in the thalamus (for essential tremor and multiple sclerosis) or in the globus pallidus (for Parkinson's disease).
In addition, the surgery to place the stimulator in the subthalamic nucleus is generally easier than surgeries for the thalamus or globus pallidus.
www.medicinenet.com /deep_brain_stimulation/article.htm   (752 words)

 ScienceDaily: Deep Brain Stimulation Offers Benefits Against Parkinson's
Deep brain stimulation via electrodes implanted on both sides of the brain markedly improves the motor skills of patients with advanced Parkinson's Disease, says a new long-term study by researchers at the University of Toronto and Toronto Western Hospital.
Deep Brain Stimulation In Parkinson Disease Reduces Uncontrolled Movements (April 17, 2005) -- Deep brain stimulation of two different areas of the brain appears to improve problems with uncontrolled movements (dyskinesia) in patients with Parkinson disease (PD), according to an article in the...
Deep brain stimulation -- Deep brain stimulation (DBS) is one of a group of treatments involving surgical implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the...
www.sciencedaily.com /releases/2003/09/030926065600.htm   (1874 words)

 Parkinson's Disease: Deep Brain Stimulation
Dystonia is a new condition for deep brain stimulation.
The results of deep brain stimulation for other forms of dystonia have not been quite as good, but depending on the type of dystonia it is encouraging.
If we put the brain cells to sleep, we won't be able to hear their conversation and would not be sure where to put the electrodes.
www.medicinenet.com /script/main/art.asp?articlekey=54292   (3345 words)

 Deep Brain Stimulation
Deep Brain Stimulation involves electrodes implanted in the brain connected to a pacemaker.
Seven years ago, he was proposed a new treatment involving brain surgery called Deep Brain Stimulation (DBS) and was one of the first people in the world to undergo this procedure.
Lesional surgery, in which the overactive areas of the brain are burned or cut, cannot be used for all patients since some areas of the brain are too sensitive to be treated in this manner.
www.firstscience.com /SITE/ARTICLES/dbs.asp   (940 words)

 :: American Parkinson Disease Association ::   (Site not responding. Last check: 2007-11-04)
When thalamotomy is performed, it is usually only done on one side of the brain because operating on both sides of the brain at the same time increases the chances of the patient developing complications, such as problems with vision and speech.
The stimulator is connected to the electrodes by thin wires (leads) that are tunneled under the skin in the neck and scalp.
Adjusting the stimulator and medications after electrode implantation is a major time commitment on the part of the neurological team and patient.
www.apdaparkinson.org /APDA/User1/DetailedInfo.aspx?url=Surgery.htm   (1319 words)

 Deep Brain Stimulation   (Site not responding. Last check: 2007-11-04)
An electrode is implanted in a specific part of the brain (the thalamus, the globus pallidus, or the subthalamic nucleus) mimicking the effect of a lesion but with the advantage of being reversible so that the electrode can be moved or removed altogether.
When the stimulator is switched "on", electrical signals are sent to the brain to stop or reduce the Parkinson's symptoms.
Deep brain stimulation is not a cure, but it can have a considerable impact on symptoms and could become the main surgical therapy for Parkinson's in the next two or three decades.
www.parkinsons.org.uk /Templates/Internal.asp?NodeID=93555   (851 words)

 Deep Brain Stimulation Slows Parkinson's Symptoms
The study found that the results of stimulating the STN, thought by many to be the preferred target for stimulation, and the GPi are generally comparable.
During stimulation therapy, a pacemaker-like device implanted under the skin near the collarbone sends electrical impulses through an insulated wire to two electrodes surgically implanted in the brain from the top of the skull.
Stimulation blocks the signals that cause the disabling motor symptoms of Parkinson's.
www.ohsu.edu /ohsuedu/newspub/releases/041305brain.cfm   (893 words)

 Deep brain stimulation: An experimental depression treatment - MayoClinic.com
Deep brain stimulation is a highly experimental treatment for depression in which the brain is stimulated with electrical impulses in an attempt to change mood.
Deep brain stimulation requires two surgical procedures — surgery on your brain to implant electrodes and surgery on your chest to implant a neurostimulator device.
Because deep brain stimulation involves brain surgery, the procedure may be especially risky.
www.mayoclinic.com /health/deep-brain-stimulation/MH00114   (792 words)

 deep brain stimulation surgery,deep brain stimulation surgery technique,deep brain stimulation
Chronic deep brain stimulation surgery is a rapidly emerging therapy for advanced Parkinson's disease.
Deep brain stimulation surgery technique involves implanting electrodes inside the deep nuclei of brain called as subthalamus.
The stimulation of subthalamic nucleus through this device leads to improvement in all the symptoms of advanced Parkinson's disease.
parkinsonindia.org /deep_brain_stimulation_surgery.htm   (580 words)

 Deep Brain Stimulation - Southeast (Richmond) PADRECC
Deep brain stimulation (DBS), a type brain surgery can be an effective treatment for reducing some of the symptoms of Parkinson’s disease.
The effects of the stimulator are reversible and can be changed or turned off by a trained healthcare professional.
In addition, the DBS procedure should not be performed on patients with cognitive decline or changes in memory not related to the medication(s) because the symptoms may be worsened.
www1.va.gov /netsix-padrecc/page.cfm?pg=1   (750 words)

 Atacand - Deep brain stimulation alters BP
The procedure, called deep brain stimulation, decreased or increased BP when different parts of the brain were activated.
Deep brain stimulation is already used to relieve pain and help Parkinson's disease sufferers regain some of their movement abilities, the researchers note.
Specifically, 10 Hz stimulation of the ventral area caused a mean systolic BP reduction of 14.2 mmHg in seven patients, while stimulation at 10 Hz of the dorsal area resulted in a mean increase of 16.7 mmHg in six patients.
www.atacand.com /secNewsItem/Deep-brain-stimulation-alters-BP.aspx?l1=1   (320 words)

 Deep brain stimulation - Wikipedia, the free encyclopedia
In neurotechnology, deep brain stimulation (DBS) is a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain.
Researchers reported in 2005 that electrical stimulation of a small area of the frontal cortex brought about a "striking and sustained remission" in four out of six patients suffering from clinical depression, whose symptoms had previously been resistant to medication, psychotherapy and electroconvulsive therapy.
Using brain imaging, the reserchers noticed that activity in the subgenual cingulate region (SCR or Brodmann area 25) — the lowest part of a band of tissue that runs along the midline of the brain — seemed to correlate with symptoms of sadness and depression.
en.wikipedia.org /wiki/Deep_brain_stimulation   (1657 words)

 LOZANO: Deep brain stimulation   (Site not responding. Last check: 2007-11-04)
The nuclear structures of the brain are populated by neurons that speak individual languages.
When we say we're applying electrical stimulation in the subthalamic nucleus (STN), what we really mean is that there's a stimulating electrode in the STN, which affects an unknown number and unknown kinds of neural elements at an unknown distance in the vicinity of the electrodes.
This suggests that stimulation may, in fact, excite axon terminals and that these axon terminals are releasing their GABA, which is going across the synaptic cleft, interacting with GABA A receptors in the post synaptic cell and shutting down activity in the post synaptic neuron.
www.vard.org /jour/01/38/6/gsted386.htm   (6536 words)

 Deep Brain Stimulation for Treatment of Movement Disorders   (Site not responding. Last check: 2007-11-04)
Deep brain stimulation suppresses tremor by delivering mild electrical stimulation to block brain signals that cause the uncontrollable shaking.
Deep brain stimulation can be done on one or both sides of the brain, depending on the disorder and the patient's problems.
Deep brain stimulation has dramatically changed the lives of many patients with uncontrollable tremors.
www.mayoclinic.org /movement-disorders/deep-brain-stimulation.html   (425 words)

 Deep Brain Stimulation for Movement Disorders   (Site not responding. Last check: 2007-11-04)
Deep brain stimulation is one of the most recent and promising advances in movement disorder surgery.
Deep brain simulation (DBS) is a technology that allows neurosurgeons to treat patients with a variety of movement disorders.
These electrodes are placed within the target brain region and are used to deliver the high frequency stimulation designed to block or disrupt the function of the surrounding brain.
www.med.ege.edu.tr /~norolbil/2001/NBD15501.html   (1814 words)

 Deep Brain Stimulation
Deep brain stimulation (DBS) electrode implanted intracranially with wires connecting to pulse generators in the intraclavicular region
Deep Brain Stimulation (DBS) is a surgical option for patients with Parkinson’s disease, Essential Tremor, dystonia, and tremor due to multiple sclerosis.
While the electrode is being advanced through the brain, the patient does not feel any pain because of the unique nature of the human brain and its inability to generate pain signals.
cms.clevelandclinic.org /neuroscience/body.cfm?id=141   (1078 words)

 ScienceDaily: Experimental Electrode Implant Treatment Shows Promise For Helping Severely Depressed
Significant clinical response was seen in four of the six study patients with chronic stimulation of the subgenual cingulate region, with sustained improvement through six months to the study endpoint.
While DBS in other brain areas has been used to treat disorders such as epilepsy and Parkinson's disease, this is the first report of DBS in the subgenual region for major depression.
It is the culmination of 15 years of research using brain imaging technology that has worked to characterize functional brain abnormalities in major depression and mechanisms of various antidepressant treatments.
www.sciencedaily.com /releases/2005/03/050308092842.htm   (2261 words)

 Deep Brain Stimulation
Attend a free deep brain stimulation educational seminar, presented by the UM Department of Neurology.
Deep brain stimulation (DBS) is a procedure used to treat Parkinson's patients.
This wire is inserted just under the skin and lead along the length of the neck up to the scalp where it is placed through a small hole in the skull.
www.umm.edu /neurosciences/deep_brain.html   (682 words)

 Deep Brain Stimulation   (Site not responding. Last check: 2007-11-04)
Dr. Michael Oh and Dr. Terry Ryan, senior resident in the division of neurosurgery, implant the electrode used in Deep Brain Stimulation.
Deep Brain Stimulation (DBS) is a Food and Drug Administration (FDA) approved procedure which targets structures in the brain that control movement and muscle function.
By applying continuous electrical stimulation to these targeted areas, signals in the brain that previously caused the disabling motor symptoms of Parkinson’s disease are blocked.
www.muhealth.org /~news/2003/DEEPBRAIN03.shtml   (594 words)

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