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Topic: Dehydratase

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	PhhB, a Pseudomonas aeruginosa Homolog of Mammalian Pterin 4a-Carbinolamine Dehydratase/DCoH, Does Not Regulate ...
		occurs in the absence of carbinolamine dehydratase (4, 29).
		The isolation and characterization of clones of 4a-hydroxytetrahydrobiopterin dehydratase.
		PhhR, a divergently transcribed activator of the phenylalanine hydroxylase gene cluster of Pseudomonas aeruginosa.
	jb.asm.org /cgi/content/full/181/9/2789 (3862 words)

	Sloan-Kettering - Diagnostic and Therapeutic Applications of Retinol Dehydratase (SK 674)
		The invention relates to retinol dehydratase and the DNA molecule that encodes it.
		Retinol dehydratase is the enzyme that synthesizes the retro-retinoid anhydroretinol in the Spodoptera frugiperda insect cell line Sf-21.
		The isolated retinol dehydratase protein or polypeptide of the present invention can be combined with a pharmaceutically acceptable carrier or used alone for administration to mammals, particularly humans, for preventing cell growth and/or uncontrolled cell growth in cells, which are growth dependent on retinol and/or 14-hydroxy-4,14-retroretinol.
	www.mskcc.org /mskcc/html/53802.cfm (153 words)

	Studies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1 -- ...
		Pterin-4a-carbinolamine dehydratase (EC 4.2.1.-) is a protein associated with aromatic amino acid hydroxylation (1).
		The PAH stimulation assay was used to determine dehydratase activities of the mutants as described previously (26, 29).
		The dehydratase activities were determined as described in Materials and Methods.
	www.pnas.org /cgi/content/full/94/25/13469 (4764 words)

	THE MERCK MANUAL, Sec. 2, Ch. 14, The Porphyrias
		Patients with ALA-dehydratase-deficient porphyria (ADP) display little activity of ALA dehydratase in erythrocytes or in nonerythroid cells, whereas their parents show about 50% enzyme activity.
		In lead poisoning, deficient erythrocyte ALA dehydratase can be restored to normal in vitro with the sulfhydryl reagent dithiothreitol, whereas a genetic deficiency of this enzyme is not restored.
		This structural analog of ALA is a potent inhibitor of the dehydratase.
	www.merck.com /mrkshared/mmanual/section2/chapter14/14c.jsp (1848 words)

	L-Serine Catabolism via an Oxygen-Labile L-Serine Dehydratase Is Essential for Colonization of the Avian Gut by ...
		Effect of phenylhydrazine, hydroxylamine, and amino acids on serine dehydratase activity in cell extracts of the C.
		Reactivation is expressed as a percentage of the activity of the enzyme stored under anaerobic conditions for the duration of the inactivation in air and subsequent reactivation with Fe and DTT.
		The peptide sequences near the bound pyridoxal phosphate are conserved in serine dehydratase from rat liver and threonine dehydratases from yeast and Escherichia coli.
	iai.asm.org /cgi/content/full/72/1/260 (5274 words)

	References - threonine dehydratase - HORT640 - Metabolic Plant Physiology - Department of Horticulture and Landscape ... (Site not responding. Last check: 2007-10-24)
		Hammer VA, Rogers QR, Freedland RA 1996 Threonine is catabolized by L-threonine 3-dehydrogenase and threonine dehydratase in hepatocytes from domestic cats (Felis domestica).
		Parsot C 1986 Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase.
		Szamosi IT, Shaner DL, Singh BK 1994 Inhibition of threonine dehydratase is herbicidal.
	www.hort.purdue.edu /rhodcv/hort640c/referen/thrdeh.htm (520 words)

	Protein Content of Polyhedral Organelles Involved in Coenzyme B12-Dependent Degradation of 1,2-Propanediol in ...
		dehydratase increased approximately 10-fold, from 2.7 to 27.5
		The approximate ratio of the C subunit of diol dehydratase
		diol dehydratase catalyzes the conversion of 1,2-PD to propionaldehyde,
	jb.asm.org /cgi/content/full/185/17/5086 (5100 words)

	Plant Gene Register PGR96-033 (Site not responding. Last check: 2007-10-24)
		The cDNA encoding IGP dehydratase was isolated from a lamda ACT pea cDNA library (J. Kim and A. Theologis, unpublished data) by complementation of yeast (Saccharomyces serevisiae) lacking the his3 gene.
		The cDNA (1229 nucleotides) encodes an IGP dehydratase proenzyme (281 amino acids) with a putative 84 amino acid chloroplast transit peptide sequence that may allow the localization of the enzyme into the chloroplasts.
		The presence of a putative transit peptide in pea IGP dehydratase proprotein raises the prospect that the enzyme may be localized in the chloroplasts.
	www.tarweed.com /pgr/PGR96-033.html (638 words)

	Possible influence of [delta]-aminolevulinic acid dehydratase polymorphism and susceptibility to renal toxicity of ...
		Possible influence of [delta]-aminolevulinic acid dehydratase polymorphism and susceptibility to renal toxicity of lead: a study of a Vietnamese population
		We examined six newly identified polymorphisms in the [delta]-aminolevulinic acid dehydratase (ALAD) single-nucleotide polymorphisms (SNPs) to determine if these SNPs could modify the relationship between blood lead (PbB) and some renal parameters.
		This is a cross-sectional study of 276 lead-exposed workers in Vietnam.
	www.findarticles.com /p/articles/mi_m0CYP/is_10_113/ai_n15736898 (347 words)

	InterPro: IPR001533 Transcriptional coactivator/pterin dehydratase (Site not responding. Last check: 2007-10-24)
		DCoH is the dimerization cofactor of hepatocyte nuclear factor 1 (HNF-1) that functions as both a transcriptional coactivator and a pterin dehydratase [ 1 ].
		O76454 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) (PHS) (4-alpha- hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD)
		Q9CZL5 Pterin-4-alpha-carbinolamine dehydratase 2 (EC 4.2.1.96) (PHS 2) (4- alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF1-alpha dimerization cofactor)
	www.ebi.ac.uk /interpro/IEntry?ac=IPR001533 (2738 words)

	NPS@ similarity search results (Site not responding. Last check: 2007-10-24)
		NPSA swTHDH_YEAST THREONINE DEHYDRATASE PRECURSOR (EC 4.2.1.16) (T...
		NPSA sptrQ39469 THREONINE DEHYDRATASE BIOSYNTHETIC PRECURSOR (EC 4...
		NPSA swSDHL_YEAST L-SERINE DEHYDRATASE (EC 4.2.1.13) (L-SERINE DEA...
	www.cs.brandeis.edu /~kapilm/richter/blast_SRmouse2.htm (342 words)

	Pfam: domain structure of proteins in the Enolase_N Seed alignment (Site not responding. Last check: 2007-10-24)
		ENO1_MAIZE P26301 Enolase 1 (EC 4.2.1.11) (2-phosphoglycerate dehydratase 1) (2-phospho- D-glycerate hydro-lyase 1).
		ENO1_YEAST P00924 Enolase 1 (EC 4.2.1.11) (2-phosphoglycerate dehydratase 1) (2-phospho- D-glycerate hydro-lyase 1).
		ENO_SHIFL P0A6Q2 Enolase (EC 4.2.1.11) (2-phosphoglycerate dehydratase) (2-phospho-D- glycerate hydro-lyase).
	pfam.wustl.edu /cgi-bin/getdomainview?name=Enolase_N (220 words)

	=ALA Syntase======================================================================= (Site not responding. Last check: 2007-10-24)
		A query for ALA dehydratase (Section II/ B. Biosynthesis of Porphobilinogen) addressed to the Various protein databases listed in the Biology Workbench, yielded 30 unique records which are depicted under Sequenced ALA Dehydratases.
		Click on Sequences to view the various ALA Dehydratase sequences retrieved from various protein sequence databases by the Biology Workbench.
		Click on Sequence Similarity Search to view the Blast soybean ALA Dehydratase sequence similarity search results from the Biology workbench.
	w3.aces.uiuc.edu /nres/lppbp/ALADeh1.html (120 words)

	ref2
		PM, (2001) The X-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with two diacid inhibitors.
		The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors.
		Highly heterogeneous nature of delta-aminolevulinate dehydratase (ALAD) deficiencies in ALAD porphyria.
	www.arches.uga.edu /~malini/references.htm (731 words)

	ALA dehydratase reaction (Site not responding. Last check: 2007-10-24)
		The ALA dehydratase reaction occurs in the cytoplasm; the product is porphobilinogen (pronounce).
		The reaction is a condensation to form porphobilinogen, the first pyrrole
		> Heme and Iron >Main Menu > Synthesis > ALA dehydratase
	www.porphyrin.net /Heme_iron/synthesis/aladehydratase.html (81 words)

	Carbonic Anhydrase I antibody (ab8952) datasheet
		Conjugation, Dot, ELISA, IP, WB CA II, CA2, CAII, Car2, Carbonate dehydratase II, Carbonic anhydrase 2, Carbonic...
		WB CA II, CA2, CAII, Car2, Carbonate dehydratase II, Carbonic anhydrase 2, Carbonic...
		Dot, ELISA, IP, WB CA II, CA2, CAII, Car2, Carbonate dehydratase II, Carbonic anhydrase 2, Carbonic...
	www.abcam.com /?datasheet=8952 (327 words)

	[No title]
		271 3e-72 gi2688968 (AF027980) imidazole glycerol phosphate dehydratase...
		161 3e-39 gi3982576 (AF023140) imidazoleglycerol phosphate dehydratase [...
		65 5e-10 >gi2506514spP06633HIS7_YEAST IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD) >gi2144537pirDWBYH imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) - yeast (Saccharomyces cerevisiae) >gi1420477embCAA99417
	proteome.bnl.gov /blast2/YOR202W.blastp (107 words)

	EC 4.2.1.24 (Site not responding. Last check: 2007-10-24)
		Other name(s): aminolevulinate dehydratase; d-aminolevulinate dehydratase; d-aminolevulinic acid dehydrase; d-aminolevulinic acid dehydratase; aminolevulinic dehydratase; d-aminolevulinic dehydratase; 5-levulinic acid dehydratase
		Komai, H. and Neilands, J.B. The metalloprotein nature of Ustilago d-aminolevulinate dehydratase.
		Yamasaki, H. and Moriyama, T. d-Aminolevulinic acid dehydratase of Mycobacterium phlei.
	www.chem.qmul.ac.uk /iubmb/enzyme/EC4/2/1/24.html (86 words)

	C.jejuni
		Cj0316, pheA, probable chorismate mutase\prephenate dehydratase, len: 357 aa; similar to many e.g.
		PHEA_ECOLI chorismate mutase (EC 5.4.99.5) \ prephenate dehydratase (EC 4.2.1.51) (386 aa), fasta scores; opt: 482 z-score: 733.8 E(): 0, 33.1% identity in 366 aa overlap.
		Contains PS00857 and PS00858 Prephenate dehydratase signatures 1 and 2, and Pfam match to entry PF00800 PDT, Prephenate dehydratase, score 268.20, E-value 1.1e-76
	www.sanger.ac.uk /Projects/C_jejuni/CDS/Cj0316.shtml (142 words)

	EC 4.3.1.19 (Site not responding. Last check: 2007-10-24)
		The enzyme from a number of sources also acts on
		The reaction catalysed probably involves initial elimination of water (hence the enzyme's original classification as EC 4.2.1.16, threonine dehydratase), followed by isomerization and hydrolysis of the product with C-N bond breakage.
		Cohn, M.S. and Phillips, A.T. Purification and characterization of a B6-independent threonine dehydratase from Pseudomonas putida.
	www.chem.qmul.ac.uk /iubmb/enzyme/EC4/3/1/19.html (161 words)

	Neisseria meningitidis
		NMA1772, hisB, imidazoleglycerol-phosphate dehydratase, len: 305aa; C-terminal similar to many eg.
		SW:P06987 (HIS7_ECOLI) hisB, imidazoleglycerol-phosphate dehydratase from Escherichia coli (355 aa) fasta scores; E(): 0, 49.7% identity in 195 aa overlap.
		Contains Pfam match to entry PF00475 IGPD, Imidazoleglycerol-phosphate dehydratase; Prosite match to PS00954 Imidazoleglycerol-phosphate dehydratase signature 1 and Prosite match to PS00955 Imidazoleglycerol-phosphate dehydratase signature 2.
	www.sanger.ac.uk /Projects/N_meningitidis/seroA/CDS/NMA1772.shtml (112 words)

	Bioperl Reformatted HTML of BLASTX output with Bioperl Bio::SearchIO system
		3-isopropylmalate dehydratase, small subunit; protein id: At2g43090.1, supported by cDNA: 31507., supported by cDNA: gi_14334969, supported by cDNA: gi_17104628 [Arabidopsis thaliana] pirH84861 3-isopropylmalate dehydratase, small subunit [imported] - Arabidopsis thaliana gbAAC64298.1
		putative 3-isopropylmalate dehydratase, small subunit [Arabidopsis thaliana] gbAAL34203.1
		putative 3-isopropylmalate dehydratase, small subunit [Arabidopsis thaliana] gbAAM15163.1
	www.biology.duke.edu /chlamy_genome/db_search/blast/nr/6/6033_1.html (256 words)

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