
	Where results make sense

Topic: Dehydrogenase

In the News (Sun 27 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Glucose-6-phosphate dehydrogenase deficiency - Genetics Home Reference
		Glucose-6-phosphate dehydrogenase deficiency is a genetic disorder that occurs most often in males.
		Mutations in the G6PD gene cause glucose-6-phosphate dehydrogenase deficiency.
		Glucose-6-phosphate dehydrogenase deficiency occurs most frequently in areas of the world where malaria is common.
	ghr.nlm.nih.gov /condition=glucose6phosphatedehydrogenasedeficiency (871 words)

	Glud1 - Glutamate dehydrogenase 1, mitochondrial precursor
		Glutamate dehydrogenase (GDH) catalyzes reversible oxidative deamination of l-glutamate to alpha-ketoglutarate.
		Glud1 is a homologue of Gdh (Glutamate dehydrogenase, mitochondrial precursor) from Drosophila melanogaster.
		Glud1 is a homologue of GLUD2 (Glutamate dehydrogenase 2, mitochondrial precursor) from Homo sapiens.
	www.ihop-net.org /UniPub/iHOP/gg/121313.html (1746 words)

	Alcohol dehydrogenase - Wikipedia, the free encyclopedia
		Alcohol dehydrogenases are a group of dehydrogenase enzymes that occur in many organisms and facilitate the conversion between alcohols and aldehydes or ketones.
		Alcohol dehydrogenase is also involved in the toxicity of other types of alcohol: for instance, it oxidizes methanol to produce formaldehyde, and ethylene glycol to ultimately yield glycolic and oxalic acids.
		In yeast and many bacteria, alcohol dehydrogenase plays an important part in fermentation: pyruvate resulting from glycolysis is converted to acetaldehyde and carbon dioxide, and the acetaldehyde is then reduced to ethanol by alcohol dehydrogenase.
	en.wikipedia.org /wiki/Alcohol_dehydrogenase (622 words)

	ry - Xanthine dehydrogenase
		We conclude that the lack of xanthine dehydrogenase in these mutants leads to the absence of urate, which is the proximate cause of paraquat sensitivity.
		An extra electrophoretic band of xanthine dehydrogenase was observed on polyacrylamide gel from extracts of wild-type flies cultured on certain levels of molybdenum, but its appearance was not always correlated with the increases in specific activity.
		Two new mutants, deficient in aldehyde oxidase and xanthine dehydrogenase, have been isolated from a wild-type stock of Drosophila melanogaster and have been provisionally termed lxd-c and lxd-d, respectively, as both mutants appear to be allelic with lxd (low xanthine dehydrogenase).
	www.ihop-net.org /UniPub/iHOP/gi/66682.html (962 words)

	Alcohol dehydrogenase - Open Encyclopedia (Site not responding. Last check: 2007-11-05)
		Alcohol dehydrogenase also oxidizes methanol to formaldehyde, and the dangerous effects of the latter are the main reason for the toxicity of the former.
		The conventional treatment of methanol poisoning involves administration of ethanol: this keeps the alcohol dehydrogenase busy with ethanol, so that the methanol can be cleared out of the system before it is converted to formaldehyde.
		The version of alcohol dehydrogenase in women is less effective than that in men, which is part of the reason that women have a lower tolerance for alcohol than men.
	open-encyclopedia.com /Alcohol_dehydrogenase (549 words)

	Encyclopedia: Lactate dehydrogenase (Site not responding. Last check: 2007-11-05)
		Please see gel electrophoresis for the principles of electrophoresis Schematic representation of a protein electrophoresis gel In chemistry and medicine, protein electrophoresis is a method of analysing a mixture of proteins by means of gel electrophoresis, mainly in blood serum (blood plasma is not suitable).
		The enzyme is also found in cerebrospinal fluid where high levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis.
		High levels of the enzyme can also be found in cases of viral meningitis, generally indicating the presence of encephalitis and poor prognosis.
	www.nationmaster.com /encyclopedia/Lactate-dehydrogenase (1388 words)

	Very long-chain acyl-coenzyme A dehydrogenase deficiency - Genetics Home Reference
		Very long-chain acyl-coenzyme A dehydrogenase deficiency is a condition that prevents the body from converting certain fats to energy, particularly during periods without food (fasting).
		People with an early onset of very long-chain acyl-coenzyme A dehydrogenase deficiency are also at risk of serious complications such as liver abnormalities and life-threatening heart problems.
		Very long-chain acyl-coenzyme A dehydrogenase deficiency is estimated to affect 1 in 40,000 to 120,000 people.
	ghr.nlm.nih.gov /condition=verylongchainacylcoenzymeadehydrogenasedeficiency (768 words)

	Glutamate Dehydrogenase - Ammonia Assimilation and Recycling - HORT640 - Metabolic Plant Physiology - Department of ...
		The mature alpha- and beta-subunits of 53,501 and 52,342 Da are identical in sequence except for an 11 amino acid extension at the N-terminus of the alpha-subunit (Miller et al, 1998).
		Abrahams GL, Abratt VR 1998 The NADH-dependent glutamate dehydrogenase enzyme of Bacteroides fragilis Bf1 is induced by peptides in the growth medium.
		Fincham JRS 1951 The occurrence of glutamate dehydrogenase in Neurospora and its apparent absence in certain mutant strains.
	www.hort.purdue.edu /rhodcv/hort640c/ammonia/am00001.htm (1399 words)

	Glucose-6-Phosphate Dehydrogenase Deficiency
		Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PDD) is an inherited, sex-linked, metabolic disorder characterized by an enzyme defect that leads to the breakdown of red blood cells (hemolysis) upon exposure to stresses associated with some bacterial infections or certain drugs.
		A deficiency of this enzyme may result in the premature destruction of red blood cells (an acute hemolytic anemia or a chronic spherocytic type) when an affected individual is exposed to certain medications or chemicals, experiences certain viral or bacterial infections, and/or inhales the pollen of, or consumes, fava beans (favism).
		Glucose- 6-Phosphate Dehydrogenase Deficiency is inherited as an X-linked genetic trait.
	my.webmd.com /hw/health_guide_atoz/nord774.asp (579 words)

	[No title]
		Conclusions: In conclusion the study indicates that glucose-6-phosphate dehydrogenase deficiency is common in the central region of Saudi Arabia and a lot of patients present with haemolytic episodes.
		Glucose 6 phosphate dehydrogenase deficiency is found in tropical and subtropical countries and is one of the important causes of haemolytic anaemia and neonatal jaundice
		Since glucose-6-phosphate dehydrogenase deficiency in marriage group exists, there is compelling need for introducing measures such as genetic counselling and public health education as part of the overall health and welfare services in the area.
	www.ayubmed.edu.pk /JAMC/PAST/14-3/SalamG6PD.htm (1393 words)

	NSDHL - NAD(P)-dependent steroid dehydrogenase
		Nsdhl is a 3beta-hydroxysterol dehydrogenase that is involved in the removal of C-4 methyl groups in the cholesterol biosynthetic pathway.
		NAD(P)H steroid dehydrogenase-like protein (Nsdhl), a mammalian C-3 sterol dehydrogenase involved in the conversion of lanosterol into cholesterol, was localized on lipid droplets by immunofluorescence microscopy and subcellular fractionation.
		Copper increased the expression of seven cholesterogenic genes (3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) synthase, IPP isomerase, squalene synthase, squalene epoxidase, methyl sterol oxidase, H105e3 mRNA and sterol-C5-desaturase) and low-density lipoprotein receptor (LDL-R), and decreased the expression of CD36 and lipid binding proteins.
	www.pdg.cnb.uam.es /UniPub/iHOP/gg/99021.html (371 words)

	Lactate Dehydrogenase Isozymes: Dissociation and Recombination of Subunits -- Markert 140 (3573): 1329 -- Science (Site not responding. Last check: 2007-11-05)
		Lactate Dehydrogenase Isozymes: Dissociation and Recombination of Subunits
		High Lactate Dehydrogenase Isoenzyme 1 in a Patient with Malignant Germ Cell Tumor Is Attributable to Aberrant Methylation of the LDHA Gene.
		Lactate Dehydrogenase of Trout: Hybridization in vivo and in vitro.
	www.sciencemag.org /cgi/content/abstract/140/3573/1329 (508 words)

	Biochemistry Study Questions on Fates of Pyruvate and Pyruvate Dehydrogenase
		Describe the role of TPP in the oxidative decarboxylation of pyruvate by pyruvate dehydrogenase.
		Describe the role of the lipoamide prosthetic group of dihydrolipoyl transacetylase in the oxidation of the hydroxyethyl-TPP complex of the pyruvate dehydrogenase complex.
		-dependent dihydrolipoyl dehydrogenase component of the pyruvate dehydroagenase complex to be a flavoprotein.
	www.umsl.edu /~starling/biochem/study/sq-18.htm (313 words)

	Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD)
		In some infants with congenital Short-Chain Acyl-CoA Dehydrogenase Deficiency, symptoms may include abnormal fluid accumulation in the brain (cerebral edema), enlargement of the liver and spleen (hepatosplenomegaly), fatty changes in the liver, suppression of the flow of bile from the liver (cholestasis), and/or progressive loss of liver function (focal hepatocellular necrosis).
		It is caused by a deficiency of the enzyme, medium-chain CoA Dehydrogenase.
		It affects infants and is caused by a deficiency of the enzyme, long-chain CoA dehydrogenase.
	hw.healthdialog.com /kbase/nord/nord1054.htm (1723 words)

	CIGNA - Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD) (Site not responding. Last check: 2007-11-05)
		Short-chain acyl-CoA dehydrogenase deficiency is an extremely rare inherited disorder of fat metabolism belonging to a group of diseases known as fatty acid oxidation disorders (FOD).
		It is caused by a deficiency of the enzyme medium-chain CoA dehydrogenase.
		It affects infants and is caused by a deficiency of the enzyme known as very-long-chain CoA dehydrogenase.
	www.cigna.com /healthinfo/nord1054.html (2224 words)

	AFGN - Aldehyde Dehydrogenase
		T-DNA mutants of SSADH1 are dwarfs with necrotic lesions and display an enhanced sensitivity to both UV-B light and heat stress that is correlated with an increase in H2O2 levels, suggesting that this gene may restrict levels of ROS intermediates in plant defense against environmental stress (Bouché et al., 2003).
		Bouché, N., Fait, A., Bouchez, D., Møller, S.G. and Fromm, H. Mitochondrial succinic-semialdehyde dehydrogenase of the gamma-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants.
		Plant J. Kirch, H.H., Nair, A. and Bartels, D. Novel ABA- and dehydration-inducible aldehyde dehydrogenase genes isolated from the resurrection plant Craterostigma plantagineum and Arabidopsis thaliana.
	www.uni-tuebingen.de /plantphys/AFGN/bartels.htm (797 words)

	PDB Molecule of the Month: Alcohol Dehydrogenase (Site not responding. Last check: 2007-11-05)
		Alcohol dehydrogenase is our primary defense against alcohol, a toxic molecule that compromises the function of our nervous system.
		Most of these are found primarily in the liver, including the beta3 form (PDB entry 1htb) and the similar enzyme from horse liver (PDB entry 6adh).
		The range of different types of alcohol dehydrogenase ensures that there will always be one that is perfect for the current task.
	www.rcsb.org /pdb/molecules/pdb13_1.html (318 words)

	Pyruvate Dehydrogenase Deficiency
		Pyruvate Dehydrogenase Deficiency is a rare disorder of carbohydrate metabolism inherited as an X-linked recessive genetic trait.
		Symptoms are caused by a deficiency of the enzyme pyruvate dehydrogenase resulting in persistent or recurrent metabolic acidosis (acidemia).
		Women who are carriers of an X-linked disorder have a 50 percent risk of transmitting the carrier condition to their daughters, and a 50 percent risk of transmitting the disease to their sons.
	hw.healthdialog.com /kbase/nord/nord413.htm (1237 words)

	Protein Expressions of Branched-Chain Keto Acid Dehydrogenase Subunits Are Selectively and Posttranscriptionally ... (Site not responding. Last check: 2007-11-05)
		of the gene encoding BCKA dehydrogenase kinase in tissues of
		The BCKA dehydrogenase activity was 100% greater in the liver
		Protein expression of branched-chain keto acid dehydrogenase subunits in liver of fed and 48-h starved rats.
	www.nutrition.org /cgi/content/full/131/6/1682 (3081 words)

	[No title] (Site not responding. Last check: 2007-11-05)
		Pyruvate is decarboxylated to acetyl-CoA by the pyruvate dehydrogenase complex and the acetyl-CoA is oxidized by the Krebs cycle.
		Isocitrate dehydrogenase I) iso-citrate + NADP+ ® oxalosuccinate + NADPH II) oxalosuccinate ® alpha-ketoglutarate + CO2 The oxalosuccinate is an enzyme bound intermediate.
		Succinate dehydrogenase Succinate + FAD ® Fumarate + FADH2 SDH is tightly bound to the membrane in close association with the electron transport chain.
	www.science.siu.edu /microbiology/micr425/KrebsCycle96 (2580 words)

	eMedicine - Pyruvate Dehydrogenase Complex Deficiency : Article by Richard E Frye, MD, PhD
		Background: Pyruvate dehydrogenase complex deficiency (PDCD) is one of the most common neurodegenerative disorders associated with abnormal mitochondrial metabolism.
		Pathophysiology: Pyruvate dehydrogenase complex (PDC) converts pyruvate to acetyl-CoA, which is one of the two essential substrates needed to produce citrate (see Image 1).
		The intramitochondrial pyruvate dehydrogenase complex is composed of 3 basic substrate-processing enzymes: a protein X and 2 regulatory enzymes.
	www.emedicine.com /ped/topic1969.htm (3544 words)

	Lactate dehydrogenase -- Facts, Info, and Encyclopedia article (Site not responding. Last check: 2007-11-05)
		As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD).
		Every LDH molecule consists of four subunits, where each subunit is either H each M (based on their (Click link for more info and facts about electrophoretic) electrophoretic properties.) There are, therefore, five LDH isotypes:
		In (A collection of pus in a body cavity (especially in the lung cavity)) empyema, the LDH levels generally will exceed 1000 U/l.
	www.absoluteastronomy.com /encyclopedia/l/la/lactate_dehydrogenase.htm (690 words)

	Genomics\|HuGENet\|Reviews\|Alcohol dehydrogenase and head/neck cancer\|PubMed ID: 14693654
		Possession of the fast metabolizing alleles for alcohol dehydrogenase (ADH), ADH1B* 2 and ADH1C* 1, and the null allele for aldehyde dehydrogenase (ALDH), ALDH2* 2, results in increased acetylaldehyde levels and is hypothesized to increase the risk of head and neck cancer.
		Alcohol dehydrogenases (ADHs) are enzymes involved in the metabolism of ethanol to acetaldehyde (1).
		Subsequent conversion of acetaldehyde to acetate is catalyzed by the mitochondrial enzyme aldehyde dehydrogenase (ALDH) (Figure 1).
	www.cdc.gov /genomics/hugenet/reviews/adh.htm (5403 words)

	Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency
		Bennett MJ, Rinaldo P, Millington DS, Tanaka K, Yokota I, Coates PM (1991) Medium-chain acyl-CoA dehydrogenase deficiency: postmortem diagnosis in a case of sudden infant death and neonatal diagnosis of an affected sibling.
		Patel JS and Leonard JV (1995) Ketonuria and medium-chain acyl-CoA dehydrogenase deficiency.
		Roe CR, Millington DS, Maltby DA, Kinnebrew P (1986) Recognition of medium-chain acyl-CoA dehydrogenase deficiency in asymptomatic siblings of children dying of sudden infant death or Reye-like syndromes.
	www.geneclinics.org /profiles/mcad/details.html (6297 words)

	A mutation in the E1 alpha subunit of pyruvate dehydrogenase associated with variable expression of pyruvate ... (Site not responding. Last check: 2007-11-05)
		A mutation in the E1 alpha subunit of pyruvate dehydrogenase associated with variable expression of pyruvate dehydrogenase complex deficiency -- Wexler et al.
		A mutation in the E1 alpha subunit of pyruvate dehydrogenase associated with variable expression of pyruvate dehydrogenase complex deficiency
		dehydrogenase heterotetramer in specific tissues because of a disruption in
	www.pedresearch.org /cgi/content/abstract/32/2/169 (258 words)

	References - formaldehyde dehydrogenase - HORT640 - Metabolic Plant Physiology - Department of Horticulture and ...
		Barber RD, Donohue TJ 1998 Function of a glutathione-dependent formaldehyde dehydrogenase in Rhodobacter sphaeroides formaldehyde oxidation and assimilation.
		Hedberg JJ, Griffiths WJ, Nilsson SJ, Hoog JO 2003 Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry.
		Uotila L, Koivusalo M 1979 Purification of formaldehyde and formate dehydrogenases from pea seeds by affinity chromatography and S-formylglutathione as the intermediate of formaldehyde metabolism.
	web.ics.purdue.edu /~drhodes/hort640c/referen/faldh.htm (603 words)

	Structure Function Relationships Among Aldehyde Dehydrogenases (Site not responding. Last check: 2007-11-05)
		Aldehyde dehydrogenase (ALDH), often in tandem with Alchohol dehydrogenase, acts in detoxifying a wide variety of organic compounds, toxins and pollutants.
		A plot of the degree of sequence similarity for pairs of sequences within the same major aldehyde dehydrogenase group compared to pairs of sequences in different groups.
		The three dimensional structure is of the Rat class III aldehyde dehydrogenase monomer.
	www.psc.edu /biomed/pages/research/Col_HBN_ALDH.html (918 words)

	Substrate specificities of peroxisomal members of short-chain alcohol dehydrogenase superfamily: expression and ...
		Substrate specificities of peroxisomal members of short-chain alcohol dehydrogenase superfamily: expression and characterization of dehydrogenase part of Candida tropicalis multifunctional enzyme -- Qin et al.
		The alignment reveals 372 members of short chain alcohol dehydrogenase superfamily (http://www.toulouse.inra.fr/prodom) (2).
		dehydrogenase was obtained by expression and purification of
	www.jlr.org /cgi/content/full/41/1/93 (2373 words)

Try your search on: Qwika (all wikis)