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Topic: Delta cell

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PP cell

Alpha cell

Islets of Langerhans

Beta cell

Pancreas

Somatostatin

Stomach

Burg Eltz

Diabetes

Energizer

Fibrinogen

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NS Mutsu

Anthony

	T-cell subtype - delta/gamma
		Delta Gamma is a provisional subtype of t-cell lymphomas.
		Source: Gamma delta T-cell neoplasms: a clinicopathological study of 11 cases.
		Gamma delta T-cell neoplasms: a clinicopathological study of 11 cases.
	www.lymphomation.org /type-t-cell-delta-gamma.htm (144 words)

	TSRI - News and Publications
		What had been learned of gamma-delta T cells in the nearly two decades since their initial discovery was that they arise early in fetal development in the thymus.
		Unlike other T cells in the body, which display a wide diversity of receptors that recognize a wide diversity of antigens - the molecular components of various pathogenic invaders - the gamma-delta T cells in the skin seem to have little, if any, diversity and display a uniform receptor and recognize only a single antigen.
		The new study showed that when skin is cut or damaged, keratinocytes, a type of epithelial cell common in the epidermis, release the antigen that is recognized by the gamma-delta T cells, which then become activated.
	www.scripps.edu /news/press/042602.html (670 words)

	MiniPleated Air Filters: Delta Filtration's C-Cell Filter (Site not responding. Last check: 2007-10-22)
		The Delta C-Cell is a synthetic mini-pleats filter derived from 100% polypropylene filter media made from a modified meltblown process.
		The Delta C-Cell is designed to be suitable for a variety of HVAC applications.
		As an additional advantage, the Delta C-Cell is sold as single slabs or as an unbranded complete unit with a plastic frame, thus facilitating manufacturers who wish to attach their own logo.
	www.deltafiltration.com /html/mini_pleats.shtm (396 words)

	V-Cell Gas Turbine Air Filters: Delta Filtration (Site not responding. Last check: 2007-10-22)
		Gas turbine filters: Delta Filtration's V-Cell pleated bagfilters are the ideal filters for gas turbine intake in a variety of locations.
		Our Delta V-Cell is a next generation product made especially for the purpose of providing clean, uniform air intake.
		Delta V-Cell gas turbine filters provide great cost-effectiveness both in performance and in disposal.
	www.deltafiltration.com /html/gasturbine.shtm (484 words)

	Matthew D. Rand
		Delta is processed by mechanism known as regulated intramebrane proteolysis (RIP), which ironically was first characterized as the mechanism by which the Notch receptor itself is activated.
		The proven utility of cultured Drosophila cell lines for expression of recombinant proteins, the relative ease of genetic manipulation of Drosophila tissues in vivo and the remarkable conservation of genes in flies and man have made Drosophila a premier tool to dissect the function of proteins.
		While full-length Delta localizes primarily to the plasma membrane and some cytoplasmic compartments, intracellular domain of Delta is seen to preferentially localize in the nucleus.
	www.uvm.edu /~annb/faculty/rand (1085 words)

	T cell receptor delta repertoire in inflamed and noninflamed colon of patients with IBD analyzed by CDR3 spectratyping ...
		T cells are a minor T cell population in humans, and their functions are still largely unknown (reviewed in Refs.
		T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage.
		T cell receptor-positive cells of the human gastrointestinal mucosa: occurrence and V region gene expression in Heliobacter pylori-associated gastritis, coeliac disease and inflammatory bowel disease.
	ajpgi.physiology.org /cgi/content/full/282/6/G1024 (4607 words)

	Search Tuna Report for islets of langerhans (Site not responding. Last check: 2007-10-22)
		There are five types of cells in an islet: beta cells, which make insulin; alpha cells, which make glucagon; delta cells, which make somatostaton; and PP cells and D1 cells, about which little is known....
		Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas....
		The beta cells of the Langerhans islets produce insulin, which lowers blood sugar and in some clinical conditions, where too much of it is around, hypoglycemia would result....
	www.searchtuna.com /ftlive2/502.html (1510 words)

	1993-1994 Scientific Report
		In view of the central role of TCR-mediated signal transduction in T cell function, it is important to understand the mechanism by which signals are passed from the exterior to the interior of the cell.
		Although SP alpha-beta+ cells were very difficult to detect in the thymus, a sufficient number escaped the blockade to partially populate the periphery, particularly with SP CD4+ T cells.
		These cells were predominantly of the CD45Rlo, L-selectinlo, CD44high phenotype typical of memory cells, presumably reflecting an imbalance between the rate of conversion of naive into memory T cells versus the very low rate of re-supply of naive cells from the thymus.
	www.fccc.edu /research/reports/scirep94/kappes94.htm (1483 words)

	Complex Proteolytic Processing Acts on Delta, a Transmembrane Ligand for Notch, during Drosophila Development -- Klueg ...
		The contribution of Delta isoforms from second instar larvae is negligible, based on previous experiments in which it was determined that a minimum of 180 mg/ml of larvae are needed to detect larval Delta isoforms by immunoprecipitation (our unpublished results).
		The Delta extracellular domain is detected with GP581 guinea pig polyclonal antiserum in panel E, and localization of the intracellular domain is assessed with MAb9E in panel F. Arrows in panel F indicate vesicles that reacts only with MAb9E.
		Technau, G.M., and Campos-Ortega, J.A. Cell autonomy of expression of neurogenic genes of Drosophila melanogaster.
	www.molbiolcell.org /cgi/content/full/9/7/1709 (7796 words)

	ipedia.com: Islets of Langerhans Article (Site not responding. Last check: 2007-10-22)
		The endocrine cells of the pancreas are grouped in the so-called Islets of Langerhans.
		The second most abundant cell type is the glucagon-releasing alpha cells (15-20%).
		Islet cells can influence each other through paracrine and autocrine communication, and beta-cells are coupled electrically to beta-cells (but not to other cell-types!).
	www.ipedia.com /islets_of_langerhans.html (241 words)

	Notch-induced Proteolysis and Nuclear Localization of the Delta Ligand -- Bland et al. 278 (16): 13607 -- Journal of ...
		The Delta protein is a single-pass transmembrane ligand for the Notch family of receptors.
		Full-length (Dlfl) and extracellular (Dlec) Delta were detected in cell lysates and medium, respectively, by Western blotting with monoclonal antibody 9B directed to the extracellular domain of Drosophila Delta.
		B, DlV5-transfected S2, Kc167, and SF9 cells were incubated with the indicated concentration of APMA and cell lysates analyzed by Western blotting with anti-V5 antibody.
	www.jbc.org /cgi/content/full/278/16/13607 (3533 words)

	Delta cell, pancreatic definition - Diabetes Mellitus, Type 2, Type 1, and Metabolic Disorders treatment and medications
		Delta cell, pancreatic: A type of cell in the pancreas (the organ of the digestive system located behind the stomach).
		Within the pancreas, the delta cells are located in areas called the islets of Langerhans.
		The delta cells make somatostatin, a hormone that inhibits the release of numerous hormones in the body.
	www.medterms.com /script/main/art.asp?articlekey=7037 (179 words)

	Mutations in {alpha}-tubulin promote basal body maturation and flagellar assembly in the absence of {delta}-tubulin -- ...
		Cells that swam to the upper 5 ml were transferred.
		Compared are ratios of sizes of daughter cells following mitotic cell division in wild-type and mutant cell populations.
		Maturation of basal bodies is hypothesized to occur at two time points in the cell cycle: early maturation occurs at the end of mitosis and a later maturation event takes palce at G2/M. Young basal bodies that show early maturation are shown in purple.
	jcs.biologists.org /cgi/content/full/117/2/303 (6430 words)

	TRDJ1 - T cell receptor delta joining 1
		A large series of 202 childhood precursor-B cell acute lymphoblastic leukemia (ALL) patients was analyzed by Southern blotting (SB) for cross-lineage rearrangements and/or deletions in the T cell receptor TCRB, TCRG and TCRD loci.
		A total of 54 primers was developed (1) to amplify rearrangements of the TCRD, TCRG, and IGK (Kde) genes as well as TAL1 deletions; (2) to sequence the junctional regions and breakpoint fusion regions; and (3) to perform MRD detection in bone marrow or peripheral blood samples during follow-up of ALL patients.
		To determine the sensitivity of heteroduplex analysis with renaturation at 4 degrees C, (c)DNA of T cell malignancies with proven clonal rearrangements was serially diluted in (c)DNA of polyclonal mononuclear peripheral blood cells and amplified using V and C primers (TCRB genes) or V and J primers (TCRG and TCRD genes).
	www.ihop-net.org /UniPub/iHOP/gg/98285.html (2249 words)

	The Body: AIDS and HIV Tuberculosis: (Gamma)(Delta) T Cell Counts Lowered in Patients
		"However, the dynamics of these cells in the peripheral blood of patients with tuberculosis with and without HIV infection is not fully understood." Both HIV infection and tuberculosis were associated with reduced levels of (gamma)(delta) T cells in peripheral blood, Carvalho and coauthors found.
		The researchers evaluated T cell populations in 74 TB patients, 20 of whom were coinfected with HIV.
		T cell counts in these patients were compared with those seen in healthy blood donors and asymptomatic HIV patients, they said.
	www.thebody.com /cdc/news_updates_archive/may1_02/hiv_tb.html (362 words)

	Hepatosplenic T-cell lymphoma: sinusal/sinusoidal localization of malignant cells expressing the T-cell receptor gamma ... (Site not responding. Last check: 2007-10-22)
		The morphologic pattern of lymphoma was that of a sinusal/sinusoidal infiltration in spleen, marrow, and liver.
		In one patient, tumor progression was associated with phenotypic changes that resulted in a CD3-TCR-gamma delta- phenotype with the same delta-gene rearrangement as initially.
		These observations suggest the existence of a new type of peripheral T-cell lymphoma characterized by its hepatosplenic presentation, and by the sinusal/sinusoidal tropism and the TCR-gamma delta phenotype of the malignant cells.
	imsdd.meb.uni-bonn.de /cgi-bin/mycite?ExtRef=MEDL/90268107 (186 words)

	Delta Cell Encyclopedia Article, Definition, History, Biography (Site not responding. Last check: 2007-10-22)
		Looking For delta cell - Find delta cell and more at Lycos Search.
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	www.jobsinart.com /search/encyclopedia/Delta_cell (225 words)

	Increased Allergen-Specific, Steroid-Sensitive gamma delta T Cells in Bronchoalveolar Lavage Fluid from Patients with ...
		T cells may be one of the cellular components involved in the
		The gamma delta chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes.
		T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4.
	www.annals.org /cgi/content/full/124/2/223 (3023 words)

	Molecular and Cellular Immunology Section, Laboratory of Immunogenetics, Division of Intramural Research, National ... (Site not responding. Last check: 2007-10-22)
		By determining the three-dimensional structures of receptors, ligands, and receptor-ligand complexes and by studying their associations in solution, we are examining the macromolecular interactions that allow the parasite to specifically invade a particular cell type.
		Some proteins are known to be essential for cell invasion; others are essential for the parasite life cycle, but their function is not known.
		The parasite receptors, being on the cell surface, are also prime candidates for the development of anti-malarial vaccines as natural immunity to malaria appears to correlate with immune responses to cell surface receptors.
	www.niaid.nih.gov /dir/labs/lig/garboczi.htm (462 words)

	T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of ... (Site not responding. Last check: 2007-10-22)
		T cells bearing T cell receptor (TCR) gamma and delta chain heterodimers are first generated early in ontogeny.
		Disruption of the mouse TCR C delta gene segment by a gene targeting method caused the complete loss of T cells bearing TCR gamma delta chains, but had little or no effect on the development of T cells bearing TCR alpha beta chains.
		The analyses of TCR gamma and delta genes in the mutant mice suggest that intracellular mechanisms acting at the level of DNA rearrangement play key roles in the differential gamma and delta gene rearrangements and in the generation of the highly restricted junctional sequences during fetal thymic development.
	www.bioscience.org /knockout/ref/itohara.htm (184 words)

	Gamma delta T cells in rhesus monkeys and their response to simian immunodeficiency virus (SIV) infection. (Site not responding. Last check: 2007-10-22)
		The outgrowth of simian gamma delta T cells in response to Daudi cells is similar to that in humans, but the exposure to IL-2 stimulates preferentially the simian V delta 1 subset rather than the V gamma 9/V delta 2 subset as found in humans.
		Upon SIV infection of the monkeys, we observed a transient increase of the percentage of total gamma delta T cell and the V gamma 9 subset.
		The results clearly indicate that gamma delta T cells in rhesus monkeys are influenced by SIV infection.
	www.aegis.com /aidsline/1996/feb/M9620730.html (530 words)

	Delta eases rules on cell phones while U wait - May 26, 1999
		NEW YORK (CNNfn) - Delta Air Lines Inc. said Wednesday it will allow passengers to use their cell phones and laptop computers while they are stuck on the tarmac waiting for take-off.
		The changes come after Delta conducted "extensive" testing to ensure that use of a cell phone or laptops won't interfere with airplane communications and navigation systems.
		The new rules, which Delta adopted voluntarily, will also allow passengers to use cell phones while their airplane sits at the gate with the boarding door open.
	money.cnn.com /1999/05/26/travelcenter/delta (402 words)

	Delta Green/Cell and Agent Dossiers
		"Delta Green remains an unofficial, illegal conspiracy within the federal government, just as it has since 1970.
		This tabfile presents brief write-ups of currently active cells and agents, with means of contact provided.
		Delta Green is an award-winning setting of modern conspiracy and Lovecraftian horror from Pagan Publishing.
	www.delta-green.com /humint/dossiers (313 words)

	Mysterious Immune Cell Seen To Promote Wound Repair
		Unlike the canonical T cells of immunology -- the white blood cells -- most gamma-delta T cells do not circulate through the bloodstream.
		In the epidermis where the gamma-delta T cells are concentrated -- numbering half a thousand cells per square centimeter -- they have a spiny, stretched-out, finger-like shape that contacts as many skin cells as possible.
		Unlike other T cells in the body, which display a wide diversity of receptors that recognize a wide diversity of antigens -- the molecular components of various pathogenic invaders -- the gamma-delta T cells in the skin seem to have little, if any, diversity and display a uniform receptor and recognize only a single antigen.
	unisci.com /stories/20022/0426022.htm (653 words)

	Down-regulation of Delta by proteolytic processing -- Mishra-Gorur et al. 159 (2): 313 -- The Journal of Cell Biology
		Full-length Delta (DlFL) was detected in the cell lysates (C), whereas DlEC is detected in the medium (M) by Western analysis with 9B antibody.
		In assessing the developmental significance of Delta cleavage,
		Delta (Dl) is cleaved and consequently inactivated either directly or indirectly by Kuzbanian (Kuz).
	www.jcb.org /cgi/content/full/159/2/313 (6894 words)

	T cell receptor delta repertoire in inflamed and noninflamed colon of patients with IBD analyzed by CDR3 spectratyping ...
		T cell receptor delta repertoire in inflamed and noninflamed colon of patients with IBD analyzed by CDR3 spectratyping -- Holtmeier et al.
		T cells might play an important role in autoimmune conditions like inflammatory bowel disease (IBD).
		T cells specific only for the inflamed mucosa.
	ajpgi.physiology.org /cgi/content/abstract/282/6/G1024 (205 words)

	Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma -- Toro ... (Site not responding. Last check: 2007-10-22)
		T-cell receptor delta gene rearrangement in childhood T-cell acute lymphoblastic leukemia.
		Primary cutaneous CD30-positive large cell lymphoma: definition of a new type of cutaneous lymphoma with a favorable prognosis: a European Multicenter Study of 47 patients.
		Cytotoxic cell antigen expression in anaplastic large cell lymphomas of T- and null-cell type and Hodgkin's disease: evidence for distinct cellular origin.
	www.bloodjournal.org /cgi/content/full/101/9/3407 (3648 words)

	PDX-1 and Cell-Cell Contact Act in Synergy to Promote {delta}-Cell Development in a Human Pancreatic Endocrine ...
		Cell lines from the fetal and adult pancreas that were developed
		When that factor was expressed in the cell lines
		Stem Cells, May 1, 2004; 22(3): 265 - 274.
	mend.endojournals.org /cgi/content/abstract/14/6/814 (482 words)

	Unusual Hematologic Malignancies: Case 3. CNS Involvement in CD56-Positive Intestinal Gamma/Delta T-Cell Lymphoma -- ...
		NK cell lymphomas, and the TCR gene is not rearranged.
		the tumor cells, and the presence of clonal TCR gene rearrangement
		Chan JKC, Sin VC, Wong KF, et al: Nonnasal lymphoma expressing the natural killer cell marker CD 56: A clinicopathologic study of 49 cases of an uncommon aggressive neoplasm.
	www.jco.org /cgi/content/full/20/17/3742 (807 words)

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