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Topic: Deoxyribonucleotide

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	NationMaster - Encyclopedia: Deoxyribonucleotide (Site not responding. Last check: 2007-10-08)
		A deoxyribonucleotide is the monomer, or single unit, of DNA, or deoxyribonucleic acid.
		Deoxyribonucleotides are synthesized by reduction of the corresponding ribonucleotides.
		Deoxyribonucleotides are synthesized from ribonucleotides by the enzyme ribonucleotide reductase
	www.nationmaster.com /encyclopedia/Deoxyribonucleotide (431 words)

	* Deoxyribonucleotide - (Biology): Definition
		DEOXYRIBONUCLEOTIDE - nucleotides which are the building blocks of DNA and which lack the 2' hydroxyl moiety present in the ribonucleotides of RNA.
		In the cell, all deoxyribonucleotides are synthesized from ribonucleotide precursors.
		deoxyribonucleic acid A polymer of deoxyribonucleotides that is in the form of a double helix; DNA is the genetic molecule of life in that it codes for the sequence of amino acids in proteins;...
	en.mimi.hu /biology/deoxyribonucleotide.html (405 words)

	KMLE: 알기쉬운 의학용어 풀이집 - deoxyribonucleic acid (DNA): 데옥시리보핵산
		이 deoxyribonucleotide의 당은 다른 deoxy- ribonucleotide의 당과 인산을 사이에 놓고 결합을 하게 되어 하나의 긴 사슬을 형성하게 된다.
		즉 당과 인산이 주축이 되어서 deoxyribonucleotide의 긴 사슬을 만든다.
		이 deoxyribonucleotide의 사슬 두 개는 각각 deoxyribonucleotide에 부착되어 있는 염기들이 결합을 하여 두 개의 사슬이 결합되어 있는 이중나선 구조를 만들게 된다.
	www.kmle.co.kr /ebook_terminology_view.php?Num=447&Md=c6728e2728fd2d74fa8d096033d6cd47&TitleLetter=deoxyribonucleic+acid+%28DNA%29%3A+%B5%A5%BF%C1%BD%C3%B8%AE%BA%B8%C7%D9%BB%EA (105 words)

	Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using ...
		Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using HIV-1 reverse transcriptase.
		Deoxyribonucleotide insertion efficiencies were measured opposite site-directed abasic template lesions using human immunodeficiency virus 1 reverse transcriptase (HIV-1RT), and the efficiencies to continue primer synthesis beyond the lesion, by addition of the next correct deoxynucleotide, were measured as a function of sequence context.
		Insertion of purines was favored over pyrimidines, A > G > T approximately C. Primer extension past the lesion occurred by two distinct mechanisms, either by direct or by misalignment extension.
	www.aegis.com /aidsline/1994/feb/M9420025.html (545 words)

	Botany online: Molecular Genetics - Genetic Code
		A direct relation exists between deoxyribonucleotide sequences (DNA) and the amino acid sequences of proteins.
		Nucleotide sequences carry the information that determines amino acid sequences, or, expressed the other way round, the amino acid sequence of a protein is encoded by a nucleotide sequence.
		Deoxyribonucleotide sequences (DNA) consist of four different nucleotides (with the bases A, T, C and G), amino acid sequences of 20 different amino acids.
	www.biologie.uni-hamburg.de /b-online/e21/21a.htm (1870 words)

	Purine and Pyrimidine Metabolism
		Regulation of the synthesis of the deoxyribonucleotides is complex
		The pattern of regulation of deoxyribonucleotide synthesis is very complex.
		Regulation of the synthesis of the deoxyribonucleotides is complex to assure the correct ratio of nucleotides for DNA synthesis
	www.db.uth.tmc.edu /faculty/alevine/1521_2000/deoxyribo.htm (1174 words)

	DNA Replication (Site not responding. Last check: 2007-10-08)
		A deoxyribonucleotide is composed of 3 parts: a molecule of the 5-carbon sugar deoxyribose, a nitrogenous base (def), and a phosphate group
		To synthesize the two chains of deoxyribonucleotides during DNA replication, the DNA polymerase enzymes involved are only able to join the phosphate group at the 5' carbon of a new nucleotide to the hydroxyl (OH) group of the 3' carbon of a nucleotide already in the chain.
		In the case of plant cells, which are surrounded by a cell wall in addition to the cytoplasmic membrane, carbohydrate-filled vesicles accumulate and fuse along the equator of the cell forming a cell plate that separates the cytoplasm into two daughter cells.
	student.ccbcmd.edu /courses/bio141/lecguide/unit6/genetics/DNA/DNArep/dnarep.html (1986 words)

	http://www.navi.net/~rsc/pchem/chap4.htm (Site not responding. Last check: 2007-10-08)
		The enzyme catalyzes the stepwise addiditon of deoxyribonucleotides to a DNA chain as shown in the picture.
		There are several required components of the reaction: all four of the deoxyribonucleotide triphosphates must be present as well as Mg DNA polymerase adds nucleotides to the 3'-hydroxy terminus of a pre-existing DNA.
		DNA polymerase catalyzes the nucleophilic attack of the 3'OH terminus of the primer on the innermost phosphorous atom (alpha-position) of a deoxyribonucleotide triphosphate.
	www.navi.net /~rsc/pchem/chap4.htm (1791 words)

	Deoxyribonucleotide - Encyclopedia, History, Geography and Biography
		The phosphate groups bind to the 5' carbon of the sugar.
		This page was last modified 20:24, 13 April 2006.
		This encyclopedia, history, geography and biography article about Deoxyribonucleotide contains research on
	www.arikah.com /encyclopedia/Deoxyribonucleotide (162 words)

	BIOML - Appendix B. Glossary
		DeoxyRibonucleic Acid: a biopolymer constructed from deoxyribonucleotides, by linking the 5' phosphate group of one deoxy-ribonucleotide to the 3' hydroxyl of another deoxyribonucleotide by a phosphodiester bond.
		Deoxyribonucleotides are the basic building blocks of DNA.
		They are composed of three parts: one beta-D-2-deoxyribose molecule (a sugar), a base (thymidine, guanine, cytosine or adenine) attached at the 1' position of the deoxyribose, and a phosphate group attached at the 5' position of the ribose.
	www.thegpm.org /BIOML/b_appb.htm (657 words)

	ChemCases: Cisplatin - 14. DNA
		The sugar present in a deoxyribonucleotide is deoxyribose, which lacks an oxygen that is present in its parent compound, ribose.
		The helical structure repeats after ten deoxyribonucleotide units on each chain (at intervals of 34 Å), as shown in Figure 1.
		One of these is DNA polymerase I, which catalyzes the step-by-step addition of activated deoxyribonucleotide units to a DNA chain; the activated deoxyribonucleotide units for adenine, guanine, thymine, and cytosine are represented as dATP, dGTP, dTTP, and dCTP, respectively.
	www.chemcases.com /cisplat/cisplat14.htm (1201 words)

	Lesson 3 Presentation 1 (Site not responding. Last check: 2007-10-08)
		The linkage takes place between the -OH group of the 3' deoxyribose carbon in one deoxyribonucleotide and the-OH group of the 5' deoxyribose carbon in another deoxyribonucleotide.
		The polarity of the phosphodiester linkages determines the polarity of the DNA strand.
		In this particular animation the polarity of the DNA strand is 5' to 3' (top to bottom), and the sequence of deoxyribonucleotides is 5'-pGpApTpC-3', this can also be written as 5'-GATC-3'; by convention the sequence of a single strand of DNA is written in the 5' to 3' orientation.
	www-unix.oit.umass.edu /~bioc565/interactive2/lesson3/presentations/presentation1/struc_dna.html (121 words)

	DNA Structure and Topology
		DNA is a double-stranded macromolecule in which each strand is a polymer of deoxyribonucleotide monomers.
		A DNA molecule is composed of two strands of deoxyribonucleotide polymers, in a very special geometric relationship in which one is entwined about the other such that an overall helical shape results.
		This is the familiar "double helix", described by Watson and Crick, in which the two helices share a common axis, and both are wound in a right-handed manner.
	www.rpi.edu /~bellos/new_page_1.htm (5130 words)

	SBNet - Research Reports 2000 (Site not responding. Last check: 2007-10-08)
		Structural studies of enzymes in the deoxyribonucleotide metabolism provide important information for understanding the structural basis for regulation, specificity and catalytic mechanism of these enzymes, and is therefore helpful for the rational design of drugs targeted at the nucleotide metabolism
		Three enzymes in the de deoxyribonucleotide metabolism have been studied.
		Protonation behaviour of carboxylate residues in the interior of proteins: Structural and mutagenesis studies of the carboxylate cluster of ribonucleotide reductase R2: Xiao-Dong Su, Martin E. Andersson, Agnes Rinaldo-Matthis,Wolfgang Blodig, Bert-Ove Persson, Britt-Marie Sjöberg and Pär Nordlund.
	xray.bmc.uu.se /sbnet/rep00/rinaldo.html (331 words)

	Adenine Ribo- and Deoxyribonucleotide Metabolism in Human Erythrocytes, B- and T-Lymphocyte Cell Lines, and ...
		Adenine Ribo- and Deoxyribonucleotide Metabolism in Human Erythrocytes, B- and T-Lymphocyte Cell Lines, and Monocyte-Macrophages -- Valentine et al.
		Ordinarily packaged in DNA, adenine deoxyribonucleotides are preferentially concentrated in erythrocyte and lymphocyte cytosol in adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) deficiency.
		The adenylate kinase-mediated partition of approximately equimolar ribo- and deoxyribonucleotide substrates yielded a very large preponderance of AMP in the monophosphate compartment, the monophosphates along being directly vulnerable to degradative loss.
	www.pnas.org /cgi/content/abstract/82/19/6682 (334 words)

	TSRI - News and Publications
		External agents such as ultraviolet radiation, which produces a variety of base modifications (mainly pyrimidine dimers), and hydroxyurea, which depletes the pool of deoxyribonucleotide triphosphates by inhibiting ribonucleotide reductase, potently impede progression of replication forks.
		Suc22 is the small subunit of ribonucleotide reductase, a critical enzyme in the synthesis of deoxyribonucleotide triphosphates used for DNA replication and repair.
		Interestingly, other Cid13 homologs in fission yeast, budding yeast, and the soil nematode Caenorhabditis elegans have been implicated in genome maintenance and cell-cycle control, suggesting a broad regulatory theme for this newly identified class of enzyme.
	www.scripps.edu /news/sr/sr2003/mb0336.html (1040 words)

	[No title]
		---------------------------------------------------------- ---------------------------------------------------------- DNA-Regulatory-Sequence A sequence of DNA deoxyribonucleotides on a DNA strand that regulates the replication or transcription of DNA.
		---------------------------------------------------------- ---------------------------------------------------------- DNA-Sequence A nucleotide sequence of deoxyribonucleotides.
		---------------------------------------------------------- ---------------------------------------------------------- Polydeoxyribonucleotide A molecular chain of deoxyribonucleotides chemically bonded by a series of phosphodiester linkages.
	www.cs.utexas.edu /users/mfkb/RKF/comp-descr.km.html (8652 words)

	Deoxyribonucleotide - The Wordbook Encyclopedia
		Thewordbook is a comprehensive encyclopedia and a reference search engine, in which you have found this entry about Deoxyribonucleotide.
		TheWordbook.com is your reference book and invites you to quarry.
		Translation - whether it means now or is called meant.
	www.thewordbook.com /Deoxyribonucleotide (215 words)

	Discrimination against Deoxyribonucleotide Substrates by Bacterial RNA Polymerase -- Svetlov et al. 279 (37): 38087 -- ...
		Discrimination against Deoxyribonucleotide Substrates by Bacterial RNA Polymerase -- Svetlov et al.
		Articles by Svetlov, V. Articles by Artsimovitch, I. Discrimination against Deoxyribonucleotide Substrates by Bacterial RNA Polymerase
		between ribo- and deoxyribonucleotide substrates as well as
	www.jbc.org /cgi/content/abstract/279/37/38087 (388 words)

	Report
		A molecular chain of deoxyribonucleotides chemically bonded by a series of phosphodiester linkages.
		A nucleotide in which the 5' terminal group is a monophosphate.
		A sequence of DNA deoxyribonucleotides on a DNA strand that regulates the replication or transcription of DNA.
	www.cs.utexas.edu /users/mfkb/RKF/report.html (6522 words)

	Anaerobic Growth of Bacillus mojavensis and Bacillus subtilis Requires Deoxyribonucleosides or DNA -- Folmsbee et al. ...
		deoxyribonucleotide pool for DNA synthesis and suggest that
		must be able to phosphorylate the deoxyribonucleoside to a deoxyribonucleotide.
		Hoff-Jorgensen, E. Microbiological assay method for deoxyribonucleosides, deoxyribonucleotides and deoxyribonucleic acid.
	aem.asm.org /cgi/content/full/70/9/5252 (3590 words)

	Biotechterms.org
		It is the growing end of the DNA chain and it simply provides a free 3'- OH end at which the enzyme DNA polymerase adds on deoxyribonucleotide units (monomers).
		Which deoxyribonucleotide is added is dictated by base pairing to the template DNA chain.
		Without a DNA primer sequence a new DNA chain cannot form since DNA polymerase is not able to initiate DNA chains.
	biotechterms.org /sourcebook/saveidretrieve.php3?id=1541 (136 words)

	Ribonucleotide Reductase Messenger RNA Expression and Survival in Gemcitabine/Cisplatin-Treated Advanced Non-Small Cell ...
		Ribonucleotide reductase converts ribonucleotide 5'-diphosphate to deoxyribonucleotide 5'-diphosphate, which is essential for DNA synthesis.
		Subsequent phosphorylation by uridylate-cytidylate monophosphate kinase generates difluorideoxycytidine 5'-diphosphate, which interferes with the function of ribonucleotide reductase and reduces the pool of deoxyribonucleotide diphosphate available for DNA synthesis.
		Overexpression of ribonucleotide reductase abrogates gemcitabine depletion of deoxyribonucleotide diphosphate, leading to efficient DNA synthesis and repair.
	clincancerres.aacrjournals.org /cgi/content/full/10/4/1318 (4208 words)

	Deoxyribonucleotide (Site not responding. Last check: 2007-10-08)
		Search for deoxyribonucleotide triphosphate in these other databases too cammino case di cura salo moravia racconti romani continuità derivabilità paese ciechi bilgietti di invito analisi de sera dì festa leopardi
		Search for deoxyribonucleotide in these other databases too Definition of deoxyribonucleotide : audigy2 zs soprattutto archelao versione latino biciclette hybrid apple ipod mini rosa 4gb loghi gratis sony ericsson t61 belli frasi home page ragazze calzature pirelli donna berretto sonagli riassunto giuseppe bertolucci villa margherita s.r.l.
		analisi promessi sposi cap 9 Induction of a Reductive Pathway for Deoxyribonucleotide Synthesis during Early Embryogenesis of the Sea Urchin.
	de-d-genome.red-path.com /deoxyribonucleotide.html (1842 words)

	Human deoxycytidine kinase is located in the cell nucleus -- Johansson et al. 94 (22): 11941 -- Proceedings of the ...
		DNA replication and repair require synthesis of deoxyribonucleotides.
		During the S-phase of the cell cycle, deoxyribonucleotides
		Enzymes involved in both the de novo synthesis of deoxyribonucleotides and DNA replication have been postulated to form a
	www.pnas.org /cgi/content/full/94/22/11941 (3171 words)

	SBNet - H. Eklund
		RNR has a unique additional allosteric regulation since triphosphate nucleotides regulate the substrate specificity in such a way that a balanced supply of the different deoxynucleotides is present during DNA synthesis.
		The reduction of a ribonucleotide to a deoxyribonucleotide is a chemically difficult reaction to perform and the reaction has to be initiated by an organic free radical.
		Most of the reductases characterised to date use an iron-containing protein for the generation of the catalytically necessary organic radical (class I).
	xray.bmc.uu.se /sbnet/eklund.html (3690 words)

	[No title]
		Primer-dependent DNA polymerase that catalyzes the repetitive addition of deoxyribonucleotide from deoxynucleotide triphosphates to the terminal 3'-hydroxyl of a DNA strand with the release of inorganic pyrophosphate.
		Tailing reactions which add complementary homopolymer tails to the 3' end of DNA vectors and cDNA
		Label 3' ends of DNA fragments with cordycepin triphosphates
	www.stratagene.com /products/displayProduct.aspx?pid=438 (288 words)

	Deoxyribonucleotide (Site not responding. Last check: 2007-10-08)
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	www.guideofpills.com /Deoxyribonucleotide.html (384 words)

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