Deoxyribose (more precisely 2-deoxyribose) is an aldopentose — a monosaccharide containing five carbon atoms, and including an aldehyde functional group.
In deoxyribose, the carbon furthest from the attached carbon is stripped of the oxygen atom in what would be a hydroxyl group in ribose.
Its close relative, deoxyribose, is a constituent of deoxyribonucleic acid (DNA), where it alternates with phosphate groups to form the 'back-bone' of the DNA polymer and binds to nitrogenous bases.
The sugar (ribose or deoxyribose) molecules in the nucleic acid are all oriented in the same direction.
Urasil is a pyrimidine base, occurring condensed with ribose or deoxyribose to form the nucleosides uridine and deoxyuridine in animal cells.
Introduction to DNA Structure(Site not responding. Last check: 2007-10-07)
The monomer units of DNA are nucleotides, and the polymer is known as a "polynucleotide." Each nucleotide consists of a 5-carbon sugar (deoxyribose), a nitrogen containing base attached to the sugar, and a phosphate group.
Deoxyribose lacks an hydroxyl group at the 2'-position when compared to ribose, the sugar component of RNA.
The deoxyribosesugars are joined at both the 3'-hydroxyl and 5'-hydroxyl groups to phosphate groups in ester links, also known as "phosphodiester" bonds.
A Structure for DNA (Nature April 2, 1953)(Site not responding. Last check: 2007-10-07)
It has been found experimentally (3,4) that the ratio of the amounts of adenine to thymine, and the ration of guanine to cytosine, are always very close to unity for deoxy ribose nucleic acid.
It is probably impossible to build this structure with a ribosesugar in place of the deoxyribose, as the extra oxygen atom would make too close a van der Waals contact.
The previously published X-ray data (5,6) on deoxyribose nucleic acid are insufficient for a rigorous test of our structure.
Note the use of "deoxyribose nucleic acid" rather than "deoxyribonucleic acid" that is more commonly used today.
D means this five-carbon sugar has the same stereochemical configuration at the Number 4 and 5 carbons as the Number 2 and 3 Carbons of D-glyceraldehyde.
"3',5' linkages" means that two deoxyribosesugars are connected to a phosphate in the middle by the Number 3 carbon on one sugar and by the Number 5 carbon on the other sugar.
Deoxyribose is made of carbon, hydrogen and oxygen atoms.
It forms one bond with the 5′ carbon on one deoxyribose and another bond with the 3′ carbon on the next deoxyribose in the chain.
Because of the way the phosphate binds to the 5′ carbon of one deoxyribose and the 3′ carbon of the other, on one end of a strand of DNA the 3′ side of the deoxyribose is free (not connected to another phosphate) and on the other end of the strand the 5′ end is free.
Deoxyribose belongs to the large family of sugars that includes sucrose (table sugar), fructose (found in fruit), and lactose (found in milk).
Let the students decide how the deoxyribose and phosphate should be represented (e.g.
For example, if students decide deoxyribose should be represented as a square, all students should thus represent their sugar and so on for all of the remaining components.
www.biol.sc.edu /~elygen/NucMod.html (606 words)
Lecture 1, Genetics(Site not responding. Last check: 2007-10-07)
Deoxyribose differs from ribose in that it has a hydrogen atom linked to the 2' carbon, rather than a hydroxyl group.
These are deoxyadenosine (adenine linked to deoxyribose), deoxycytidine (cytosine linked to deoxyribose), deoxyguanosine (guanine linked to deoxyribose), and thymidine (thymine linked to deoxyribose).
The biosynthesis of deoxyribose was studied with effect on capillaries.
Comparisons of the tracer patterns in ribose and deoxyribose isolated from the nucleic acids of skin and liver suggest that in young tissues the formation of deoxyribose may occur by direct reduction from ribose or via an intermediate common to ribose.
The data obtained from the livers of young adults do not support this concept unless the pattern of C/sup 14/ in the ribose which is the precursor of deoxyribose, is different from that of the ribose isolated from the RNA.
We identified in the genome of Salmonella enterica serovar Typhi the gene encoding deoxyribokinase, deoK.
deoxyribose by a factor of 70, compared to the parent
Bernier-Febreau, C., du Merle, L., Turlin, E., Labas, V., Ordonez, J., Gilles, A.-M., Le Bouguenec, C. Use of Deoxyribose by Intestinal and Extraintestinal Pathogenic Escherichia coli Strains: a Metabolic Adaptation Involved in Competitiveness.
EvC Forum: Are the sugars ribose and deoxyribose self assembling(Site not responding. Last check: 2007-10-07)
I can't find any study which shows if ribose and deoxyribose are self assembling or if they need to be assembled in a living organism like the sugar glucose.
My intrest is that if robose and deoxyribose can't self assemble then they must be produced in living things in a similar matter as glucose through the Calvin cycle in plants.
Yet we are confronted with every cell on earth that is filled with more nonrandom information, which would fill thousands of pages of books, and we try to expain it all away.
The sugar is deoxyribose in the C2'-endo conformation, and geometries for the gamma torsion angle (synclinal), the chi torsion angle (antiperiplanar), and the C3*-O3* and C5*-O5* bonds are inserted from other models.
The sugar is deoxyribose in the C3'-endo conformation, and geometries for the gamma torsion angle (synclinal), the chi torsion angle (antiperiplanar), and the C3*-O3* and C5*-O5* bonds are inserted from other models.
Model constructed for protonated 2'-deoxycytidine from subcomponents for protonated base and sugar.
The protoplasm composing the nucleus of a cell; karyoplasm.
A heterocyclic nitrogenous base, particularly a purine or pyrimidine, in N-glycosidic linkage with a sugar, particularly a pentose; it is often used specifically to denote a compound obtained by hydrolysis of nucleic acids, a purine or pyrimidine linked to ribose or deoxyribose, e.g., adenosine or cytidine.
Any of several compounds that consist of a ribose or deoxyribosesugar joined to a purine or pyrimidine base and to a phosphate group and that are the basic structural units of RNA and DNA.