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Topic: Desloratadine

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	desloratadine - Allergies: Allergy Symptoms, Treatment, and Medications on MedicineNet.com
		Desloratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of H1 receptor-containing cells by histamine.
		Desloratadine was approved by the FDA in December, 2001.
		PRESCRIBED FOR: Desloratadine is used for the treatment of allergies and chronic urticaria (hives) in adults and children 12 years of age or older.
	www.medicinenet.com /desloratadine/article.htm (485 words)

	Desloratadine (Clarinex)
		Desloratadine, a major metabolite of loratadine, is a new non-sedating antihistamine.
		Desloratadine absorption is rapid and is not affected by food.
		Desloratadine is primarily metabolized to the active metabolite 3-hydroxydesloratadine.
	uuhsc.utah.edu /pharmacy/bulletins/desloratadine.html (471 words)

	Clarinex (Desloratadine) drug description - prescription drugs and medications at RxList
		CLARINEX (desloratadine) Tablets are light blue, round, film coated tablets containing 5 mg deslorata-dine, an antihistamine, to be administered orally.
		brand of desloratadine orally-disintegrating tablets is a pink colored round tablet shaped units with a "C" debossed on one side.
		Desloratadine is a white to off-white powder that is slightly soluble in water, but very soluble in ethanol and propylene glycol.
	www.rxlist.com /cgi/generic/clarinex.htm (269 words)

	Desloratadine and Pseudoephedrine (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-10-29)
		Desloratadine and Pseudoephedrine ((des-LOR-at-a-deen and soo-doe-e-FED-rin)) is a combination of two medicines used to treat nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.
		Desloratadine works by preventing the effects of a substance called histamine, which is produced by the body.
		Desloratadine and pseudoephedrine combination is not recommended for use in pediatric patients under 12 years of age.
	www.mayoclinic.com /health/drug-information/DR500599 (1302 words)

	Does Desloratadine (Clarinex) Offer Effective Relief of Nasal Symptoms of Allergy?
		Desloratadine, a metabolite of loratadine, was developed with the goal of retaining the efficacy and safety of the newer-generation antihistamines, extending the potency and duration of action, and enhancing decongestant activity (see FIGURE).
		Also, the use of desloratadine in patients with chronic idiopathic urticaria was associated with significant reductions in pruritus, number of hives, size of the largest hive, and interference with sleep and daily activities.
		Desloratadine is excreted in the urine, predominantly as metabolites.
	www.uspharmacist.com /oldformat.asp?url=newlook/files/Drug/Clarinex.htm&pub_id=8&article_id=914 (1854 words)

	Desloratadine (Systemic) - MayoClinic.com
		Desloratadine has not been studied in pregnant women.
		Desloratadine has been tested in patients 65 years of age and older and has not been shown to cause different side effects or problems in older people than it does in younger adults.
		Desloratadine may be taken with or without food or on a full or empty stomach.
	www.mayoclinic.com /health/drug-information/DR500377 (1369 words)

	News - Desloratadine Improves Productivity and Symptoms in Patients with Seasonal Allergic Rhinitis: Presented at ACAAI
		To assess the effects of desloratadine on parameters of managerial performance in patients with SAR and to assess its efficacy in reducing symptoms of SAR, Dr. Satish's team conducted a randomised, double-blind, placebo-controlled, cross-over, single-center study.
		Desloratadine significantly improved performance in six of nine parameters compared with placebo in symptomatic patients.
		The desloratadine treated group also improved in the performance parameters of basic activity level, breadth of approach, and strategy when compared to the symptomatic, placebo-treated group, but the level of improvement did not reach the level recorded in the asymptomatic condition.
	www.docguide.com /news/content.nsf/news/8525697700573E1885256C750055D803 (569 words)

	Pharmacy Times: Clarinex (Desloratadine)
		Deslorata-dine (Clarinex, Schering-Plough Corporation, NJ) is the active metabolite of loratadine and was recently approved for the relief of both nasal and non-nasal symptoms of seasonal allergic rhinitis in adult patients.
		Desloratadine is extensively metabolized in the liver and has an active metabolite 3-hydroxydeslorata-dine, which is ultimately glucuronidat-ed.
		According to four major studies, 1,838 patients were randomized to desloratadine (2.5 to 20 mg daily) or a placebo for 2 to 4 weeks.
	www.pharmacytimes.com /article.cfm?ID=294 (521 words)

	Definition of Desloratadine
		Desloratadine is a tricyclic antihistamine, which has a selective and peripheral H
		Desloratadine is rapidly absorbed from the gastro-intestinal tract.
		Desloratadine is moderately bound to plasma proteins (85%).
	www.wordiq.com /definition/Desloratadine (215 words)

	AAAAI: Desloratadine Cuts Perennial Allergic Rhinitis Symptoms (Site not responding. Last check: 2007-10-29)
		Results showed that desloratadine was significantly (p=0.001) more effective than placebo at decreasing AM/PM reflective TSS (rhinorrhoea, nasal congestion/itching, sneezing, itching/burning eyes, tearing-watering eyes, itching of ears or palate) after 4 weeks of treatment.
		Desloratadine consistently reduced TSS (including nasal congestion) for all time points and intervals, and the difference between treatment groups was statistically significant (p
		Desloratadine demonstrated significant (p<0.01) decreases in reflective total non-nasal symptom scores compared with placebo at all time points and intervals beginning on Day 2.
	www.pslgroup.com /dg/22dbae.htm (452 words)

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