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Topic: Dexamethasone


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In the News (Sat 2 Jun 12)

  
  812. Dexamethasone (WHO Food Additives Series 33)
EXPLANATION Dexamethasone is a potent synthetic analogue of hydro-cortisone that has a long history of use in veterinary medicine for the treatment of a range of metabolic diseases and inflammatory disorders in companion and farm animals.
Dexamethasone is rapidly excreted in urine and faeces.
In a study with rats orally dosed with 0.5, 1, 1.5, 2, or 4 µg/kg bw/day dexamethasone for 7 days the corticosterone concentration was reduced in the highest-dose group and the activity of tyrosine aminotransferase in the liver was increased in a dose-related manner at 2 and 4 µg/kg bw/day.
www.inchem.org /documents/jecfa/jecmono/v33je09.htm   (4914 words)

  
 Dexamethasone Information on Healthline
Dexamethasone may also be called by its brand name, Decadron, and is one of the corticosteroids.
Dexamethasone may be used to decrease abnormally high levels of potassium that develop in association with cancer.
Dexamethasone should be used cautiously in patients with kidney or liver problems, hypothyroidism, high blood pressure, or a history of heart attack.
www.healthline.com /galecontent/dexamethasone   (951 words)

  
 Dexamethasone - Wikipedia, the free encyclopedia
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid hormones.
Dexamethasone is also given in cord compression where a tumor is compressing the spinal cord.
Dexamethasone is also used in certain hematological malignancies, especially in the treatment of multiple myeloma, in which dexamethasone is given alone or together with thalidomide (thal-dex) or a combination of adriamycin and vincristine (VAD).
en.wikipedia.org /wiki/Dexamethasone   (1043 words)

  
 Howstuffworks "Dexamethasone: A Profile of a Cortisonelike Drug"
Dexamethasone belongs to a group of drugs known as adrenocorticosteroids (or cortisonelike medications).
Dexamethasone is used to treat a variety of disorders, including endocrine and rheumatic disorders; asthma; blood diseases; certain types of cancer; eye disorders; gastrointestinal disturbances, such as ulcerative colitis; respiratory diseases; and inflammations such as arthritis, dermatitis, and poison ivy.
Dexamethasone can increase the elimination of aspirin and isoniazid from the body, thereby decreasing the effectiveness of these two medications.
health.howstuffworks.com /define-dexamethasone.htm   (1086 words)

  
 Dexamethasone suppression test
Dexamethasone suppression test measures the response of the adrenal glands to ACTH.
Dexamethasone is given and levels of cortisol are measured.
Dexamethasone is a synthetic steroid similar to cortisol, which suppresses ACTH secretion in normal people.
www.pennhealth.com /ency/article/003694.htm   (607 words)

  
 National MS Society | Decadron (Dexamethasone)   (Site not responding. Last check: 2007-10-11)
Dexamethasone is one of a group of corticosteroids (cortisone-like medicines) that are used to relieve inflammation in different parts of the body.
Dexamethasone is commonly used for this oral taper.
Oral dexamethasone may also be used instead of the high-dose, intravenous treatment if the intravenous treatment is not desired or is medically contraindicated.
www.nationalmssociety.org /Meds-Dexamethasone.asp   (898 words)

  
 Dexamethasone Information on Healthline
Dexamethasone is used to treat many different conditions.
Dexamethasone weakens the body's immune response and thus its ability to fight infection.
Dexamethasone is in the FDA pregnancy category C. This means that it is not known whether dexamethasone will harm an unborn baby.
www.healthline.com /multumcontent/dexamethasone   (803 words)

  
 1800PetMeds.com - Dexamethasone 0.5mg Scored Tablets
Dexamethasone is used to treat a number of conditions including allergies, inflammation, Addison's disease, certain types of colitis and many other diseases.
Dexamethasone is a corticosteroid used to treat a variety of conditions including lupus, arthritic inflammation, allergies, cancers, brain swelling and other conditions.
Not all forms of dexamethasone are FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats.
www.1800petmeds.com /pdetail.asp?SK=10740   (541 words)

  
 dexamethasone oral - Arthritis and arthritic conditions, medications, and treatment on MedicineNet.com
Dexamethasone is also used in the treatment of blood cell cancers (leukemias), and lymph gland cancers (lymphomas).
Finally, dexamethasone is used as a hormone replacement in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.
Gradually tapering dexamethasone not only minimizes the symptoms of corticosteroid insufficiency, it also reduces the risk of an abrupt flare of the disease under treatment.
www.medicinenet.com /dexamethasone_oral/article.htm   (763 words)

  
 [No title]
Use of the steroid dexamethasone in preterm infants with respiratory distress syndrome is associated with a significantly increased incidence of cerebral palsy and developmental delay, according to new research.
Researchers compared a three-day course of dexamethasone with a placebo (saline) administered from before 12 hours of age in preterm infants, who were being treated for respiratory distress syndrome (RDS) and had received surfactant treatment.
RDS is a disorder that occurs in premature infants and is characterized by a deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing, and by the accumulation of a protein-containing film lining the alveoli and their ducts.
www.mercola.com /2000/nov/5/steroids.htm   (872 words)

  
 MedlinePlus Drug Information: Dexamethasone Oral
Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands.
Dexamethasone is also used to treat certain types of cancer.
Dexamethasone makes your stomach and intestines more susceptible to the irritating effects of alcohol, aspirin, and certain arthritis medications: this effect increases your risk of ulcers.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682792.html   (1123 words)

  
 Dexamethasone
Dexamethasone is a member of the glucocorticoid class of hormones.
Dexamethasone is commonly used for several weeks or even months at a time to get a chronic process under control.
Dexamethasone is considered to be a long acting steroid, meaning that a dose lasts about two or two-and-a-half days.
www.marvistavet.com /html/body_dexamethasone.html   (650 words)

  
 Dexamethasone Helps Radiation-Induced Nausea - National Cancer Institute
Addition of the steroid drug dexamethasone to standard supportive care for patients undergoing radiation therapy to the stomach area provided significantly better complete control of vomiting, lower levels of nausea, and less use of emergency anti-nausea medications during the course of treatment.
A dexamethasone pill was given to the experimental group once a day during the first five radiation therapy fractions.
They note that in absolute terms, dexamethasone provided an 11 percent benefit in complete control of vomiting and a 6 percent benefit in complete control of nausea for the study period of 15 days.
www.cancer.gov /clinicaltrials/results/dexamethasone0806   (750 words)

  
 Dexamethasone
Dexamethasone decreases nausea and vomiting caused by other chemotherapy drugs, kills some types of cancer cells, and decreases brain swelling after injury or illness.
Dexamethasone is taken by mouth or injected into the veins.
Dexamethasone can decrease the ability of your body to fight infections, especially if you are taking other medicine for your cancer.
www.hci.utah.edu /patientdocs/hci/drugs/dexamethasone.htm   (668 words)

  
 Defective Drug Information -Dexamethasone
The drug is a steroid medicine and dexamethasone is sometimes given to premature infants because it was thought that the dexamethasone could prevent chronic lung disease.
When dexamethasone is used for chronic treatment, many dexamethasone side effects can occur because of the adrenal suppression it leads to.
Dexamethasone suppresses the body’s inflammatory response and often allows infection to occur as a result.
www.adrugrecall.com /dexamethasone/dexamethasone.html   (181 words)

  
 Intravenous dexamethasone for extubation of newborn infants
For the population as a whole, dexamethasone prior to extubation reduced the use of endotracheal reintubation [RR 0.18 (0.04,0.97), RD -0.086 (-0.162,-0.010)].
Dexamethasone was also effective in reducing the incidence of postextubation stridor [RR 0.39 (0.16,0.93), RD -0.167 (-0.307, -0.027), NNT 6 (3,37)].
It is possible that the benefits of dexamethasone derive, at least in part, from the improvements in pulmonary compliance demonstrated by Couser 1992, an effect that may have diminished over a longer period.
www.nichd.nih.gov /cochrane/Davis2/Davis.htm   (3472 words)

  
 Patient Education - Drugs - dexamethasone
Dexamethasone is used to treat a wide range of disorders such as asthma and arthritis.
Dexamethasone is ranked C. Always consult your physician before taking any drug during or when planning pregnancy.
With dexamethasone, the most annoying side effect for patients generally is the puffiness in the face and neck that can occur.
www.gicare.com /pated/dexamethasone.htm   (1031 words)

  
 Early Postnatal Dexamethasone Therapy for the Prevention of Chronic Lung Disease in Preterm Infants With Respiratory ...
Durand M, Sardesai S, McEvoy C Effects early dexamethasone therapy on pulmonary mechanics and chronic lung disease is very low birth weight infants: a randomized, controlled trial.
Eronen M, Kari A, Pesonen E, Hallman M The effect of antenatal dexamethasone administration on fetal and neonatal ductus arteriosus: a randomized double-blind study.
Wilson DM, Baldwin RB, Ariagno RL A randomized, placebo-controlled trial of effects of dexamethasone on hypothalamic-pituitary-adrenal axis in premature infants.
pediatrics.aappublications.org /cgi/content/full/100/4/e3   (4470 words)

  
 Dexamethasone 8 mg in combination with ondansetron 4 mg appears to be the optimal dose for the prevention of nausea and ...
Dexamethasone 8 mg in combination with ondansetron 4 mg appears to be the optimal dose for the prevention of nausea and vomiting after laparoscopic cholecystectomy
Dexamethasone for prophylaxis of nausea and vomiting after epidural morphine for post-caesarean section analgesia: comparison of droperidol and saline.
Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair.
www.cja-jca.org /cgi/content/full/49/9/922   (2098 words)

  
 Dexamethasone Suppression Tests / Cushing's Help and Support   (Site not responding. Last check: 2007-10-11)
Dexamethasone suppression tests have been employed for more than 30 years in the evaluation of patients with Cushing's syndrome.
Dexamethasone often fails to suppress the function of the hypothalamus, pituitary, and
A formal low dose Dexamethasone suppression test is performed as specified above, except that a 9th dose of Dexamethasone is taken at 6:00 AM on day three.
www.cushings-help.com /dex_tests.htm   (842 words)

  
 ADAP drugs: dexamethasone   (Site not responding. Last check: 2007-10-11)
Dexamethasone suppresses inflammation and normal immune response, and is used systemically and locally to treat chronic inflammatory disorders, severe allergies, and other diseases.
If youíve been taking dexamethasone for over a period of a year, you may need to take it at times of high stress such as surgery or serious illness until your adrenal glands recover their function.
Dexamethasone is not compatible with daunorubicin, doxorubicin, mataraminol or vancomycin.
www.aegis.com /factshts/network/access/drugs/dexa.html   (447 words)

  
 Dexamethasone 21 Isoniconate, Anti-inflammatory Horse Medication
Dexamethasone-21-isonicotinate is an esterified form of dexamethasone that is approved and marketed for horses.
Dexamethasone 21 isoniconate is generally used as an anti-inflammatory drug in the treatment of musculoskeletal problems.
Dexamethasone 21 isoniconate is given by intra-muscular injection.
www.wedgewoodpharmacy.com /dexamethasone.asp   (882 words)

  
 MedlinePlus Drug Information: Dexamethasone Ophthalmic
Dexamethasone reduces the irritation, redness, burning, and swelling of eye inflammation caused by chemicals, heat, radiation, infection, allergy, or foreign bodies in the eye.
Dexamethasone eye drops may be used to reduce redness, burning, and swelling or inflammation in the ear.
If the brand of dexamethasone you are using contains benzalkonium chloride, wait at least 15 minutes after using the medicine to put in soft contact lenses.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682869.html   (865 words)

  
 Tobramycin And Dexamethasone (Ophthalmic) - MayoClinic.com
Tobramycin (toe-bra-MYE-sin) and dexamethasone (dex-a-METH-a-sone) is a combination of an antibiotic and a corticosteroid (kor-ti-ko-STER-oid).
However, in animals, the dexamethasone part of the medicine caused birth defects when it was applied to the eyes.
It is not known how much ophthalmic tobramycin and dexamethasone is absorbed into the body, or how much passes into breast milk.
www.mayoclinic.com /health/drug-information/DR203776   (1086 words)

  
 Overnight Dexamethasone Suppression Test
The overnight dexamethasone suppression test involves taking a dose of a corticosteroid medication called dexamethasone to see how it affects the level of a hormone called cortisol in the blood.
Dexamethasone, which is like cortisol, decreases the pituitary release of ACTH, which in turn decreases the adrenal gland release of cortisol.
An overnight dexamethasone suppression test is a screening test for Cushing's syndrome.
www.webmd.com /hw/health_guide_atoz/hw6479.asp   (1016 words)

  
 dexamethasone   (Site not responding. Last check: 2007-10-11)
Dexamethasone is a synthetic steroid that is chemically related to the natural hormones secreted by the adrenal cortex.
In emergency care, dexamethasone is generally used in the treatment of allergic reactions, asthma, spinal cord injury and occasionally the management of shock.
Due to onset of action, dexamethasone should not be considered a first-line medication for allergic reactions
www.templejc.edu /dept/ems/drugs/dexamethasone.html   (122 words)

  
 Medical Dictionary: Dexamethasone - WrongDiagnosis.com
Dexamethasone: A synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland).
Dexamethasone Sodium Phosphate 4 mg/1 ml Injection, SPC from the eMC
Dexamethasone Sodium Phosphate 120 mg /5 ml Injection, SPC from the eMC
www.wrongdiagnosis.com /medical/dexamethasone.htm   (284 words)

  
 A Three-day Course of Dexamethasone Therapy to Prevent Chronic Lung Disease in Ventilated Neonates: A Randomized Trial ...
Yoder MC, Chua R, Tepper R Effect of dexamethasone on pulmonary inflammation and pulmonary function of ventilator-dependent infants with bronchopulmonary dysplasia.
Early postnatal dexamethasone therapy for the prevention of chronic lung disease in premature infants with respiratory distress syndrome: a multicenter clinical trial.
Tapia JL, Ramirez R, Cifuentes J, The effect of early dexamethasone administration on bronchopulmonary dysplasia in preterm infants with respiratory distress syndrome.
pediatrics.aappublications.org /cgi/content/full/104/1/91   (5306 words)

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