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Topic: Diazepam


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Diazepam is used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
Diazepam is mainly used to treat anxiety, insomnia, and symptoms of acute alcohol or opiate withdrawal.
Diazepam is rarely used as a primary drug for the long-term treatment of epilepsy.
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 Diazepam - Wikipedia, the free encyclopedia
Diazepam was the second benzodiazepine to be invented by Leo Sternbach of Hoffmann-La Roche, and was approved for use in 1963.
Diazepam was the top-selling pharmaceutical in the United States from 1969 to 1982, with peak sales in 1978 of 2.3 billion pills.
(lethal dose in 50% of the population) of diazepam is 720mg/kg in mice and 1240mg/kg in rats.
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Diazepam / Valium is used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
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Diazepam is highly lipid soluble and is widely distributed throughout the body.
Diazepam is metabolized in the liver to several metabolites, including desmethyldiazepam (nordiazepam), temazepam, and oxazepam, all of which are pharmacologically active.
Too rapid of an injection of intravenous diazepam in small animals or neonates, may cause cardiotoxicity secondary to the propylene glycol in the formulation.
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Diazepam affects chemicals in the brain that may become unbalanced and cause anxiety, seizures, and muscle spasms.
Diazepam is in the FDA pregnancy category D. This means that diazepam is known to harm an unborn baby.
Diazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants.
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Diazepam is also used for the treatment of agitation, tremors, delirium, seizures, and hallucinations as a result of alcohol withdrawal.
Diazepam is used to abort active seizures and can be combined with other drugs in treating severe recurrent seizures.
Diazepam is metabolized by the liver and excreted mainly by the kidney.
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Valium (diazepam) is an anti-anxiety agent (benzodiazepine) used primarily for short-term relief of mild to moderate anxiety and the associated nervousness and tension.
Valium (diazepam) affects chemicals in the brain that may become unbalanced and cause anxiety, seizures and muscle spasms.
If Valium (diazepam) is taken with certain other drugs, the effects of either could be increased, decreased, or altered.
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