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Topic: Diffusion tensor imaging


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  Diffusion Tensor Imaging
Diffusion tensor imaging allows the observation of molecular diffusion in tissues in vivo and therefore the molecular organization in tissues.
The goal is to match diffusion tensor images of neonates, and to build an enabling technology to ultimately generate a statistical atlas of the development of the brain in babies between 28 and 40 weeks postconceptional age.
To better understand the characteristics of diffusion tensors and to be able to prove the correctness of the algorithms, a new way of displaying diffusion tensors was implemented.
www.rsierra.com /DA   (500 words)

  
 Diffusion Tensor Imaging Lab
Recall that the diffusion signal E(q) is related to the diffusion tensor D by the relationship
The eigensystem, i.e., the eigenvectors and associated eigenvalues, of the diffusion tensor D relects the orientational structure of the tissue within a voxel.
For each of the 7 diffusion gradients (see Description of acquired data), explain the relative diffusion signal in terms of the fiber orientation at that point in the callosum.
www.mit.edu /~hst.583/lab-manuals/lab4/HST583-Lab4.html   (1069 words)

  
 Diffusion Tensor MR Imaging of the Brain and White Matter Tractography -- Melhem et al. 178 (1): 3 -- American Journal ...
Diffusion anisotropy is predominantly caused by the orientation
MR imaging in brain tumors [75], migraines [76], and eclampsia [77].
Diffusion tensor MR imaging of the brain: effect of diffusion weighting on trace and anisotropy measurements.
www.ajronline.org /cgi/content/full/178/1/3   (6926 words)

  
 Diffusion tensor MR imaging of principal directions: a tensor tomography approach
The tensor tomography data acquisition method (rotating diffusion gradients) leads to a unique reconstruction of principal directions, whereas the conventional MRI acquisition technique (stationary diffusion gradients) leads to an ambiguous reconstruction of principal directions when the same number of measurements are used.
A computer-generated phantom was used to simulate the diffusion tensor field in the mid-ventricular region of the myocardium.
The principal directions of the diffusion tensor field were assumed to align with the fibre structure of the myocardium.
stacks.iop.org /0031-9155/47/2737   (354 words)

  
 Diffusion Tensor Imaging - Tensor Field Methods - Research - Scientific Computing and Imaging Institute
Diffusion tensor MRI visualization is a growing field of research.
The success of diffusion magnetic resonance imaging (MRI) is deeply rooted in the powerful concept that during their random, diffusion-driven displacements, molecules probe tissue structure at a microscopic scale well beyond the usual image resolution.
As diffusion is truly a three dimensional process, molecular mobility in tissues may be anisotropic, as in brain white matter.
www.sci.utah.edu /research/diff-tensor-imaging.html   (262 words)

  
 New technologies shed light on schizophrenia
Diffusion tensor imaging, a type of MRI, relates the size of keybrain-fiber bundles to different neuropsychological signs Washington -- Researchers at the Boston Veterans Affairs Health Care System - Brockton Division, Harvard Medical School, and the University of Massachusetts-Boston are using new imaging technology to gather valuable information about the brains of people with schizophrenia.
Diffusion tensor imaging (DTI) uses a regular MRI machine to analyze the movement of water molecules in and around the fibers that connect different parts of the brain.
Neuroscientists use DTI to track indicators of brain "connectivity" - factors such as the number, thickness, density and arrangement of axons (the hair-like extensions of neurons, which send messages to other neurons) and thickness of the insulating/conducting fatty myelin sheath in which they are embedded.
www.medicalnewstoday.com /medicalnews.php?newsid=15428   (804 words)

  
 Demonstration of Primary and Secondary Muscle Fiber Architecture of the Bovine Tongue by Diffusion Tensor Magnetic ...
Diffusion tensor MRI was performed on fresh excised cow tongues.
At each voxel, the orientation of the first and second eigenvectors of the diffusion tensor is represented graphically by the end-planes of cylinders.
Anisotropy of water diffusion in the myocardium of the rat.
www.biophysj.org /cgi/content/full/80/2/1024   (2622 words)

  
 Continuum, the Magazine of the University of Utah - Summer 2004
Employing diffusion tensor imaging, a technique that uses the dispersal of water molecules through cells, the researchers will look more closely at the white matter in the brains of study participants.
Diffusion tensor imaging allows much more detailed study of white matter, including how fibers are organized.
Diffusion tensor imaging has potential applications for other disorders and diseases, such as strokes, MS, amyotrophic lateral sclerosis (Lou Gehrig’s disease), tumors, and spinal cord injuries.
www.alumni.utah.edu /continuum/summer04/inside_view.htm   (2103 words)

  
 Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging -- ...
The voxel components of the diffusion tensor were determined by multilinear regression (3), and determination of the eigensystem
Diffusion anisotropy in excised normal rat spinal cord measured by NMR microscopy.
Diffusion tensor MR imaging of the human brain.
ajpheart.physiology.org /cgi/content/full/275/6/H2308   (7105 words)

  
 Imaging Research Center, Cincinnati Children's Hospital Medical Center
The Imaging Research Center (IRC) is an interdisciplinary research laboratory operated by the Cincinnati Children's Research Foundation (CCRF) and the Department of Radiology at Cincinnati Children's Hospital Medical Center (CCHMC).
The IRC was established in 1993 and is led by Bernard J. Dardzinski, PhD, Division Chief of Radiology Research and the Imaging Research Center.
The IRC provides access to advanced imaging and image post-processing methods for collaborators involved in basic and clinical research at Cincinnati Children's and the University of Cincinnati Medical Center for the purpose of advancing the research goals of both institutions.
www.cincinnatichildrens.org /research/cores/irc   (482 words)

  
 Inter-Sequence and Inter-Imaging Unit Variability of Diffusion Tensor MR Imaging Histogram-Derived Metrics of the Brain ...
Inter-Sequence and Inter-Imaging Unit Variability of Diffusion Tensor MR Imaging Histogram-Derived Metrics of the Brain in Healthy Volunteers -- Cercignani et al.
of diffusion tensor MR imaging in the context of longitudinal
Diffusion tensor MR imaging holds significant promise for the
www.ajnr.org /cgi/content/full/24/4/638   (3865 words)

  
 Characterization of White Matter Damage in Ischemic Leukoaraiosis with Diffusion Tensor MRI -- Jones et al. 30 (2): 393 ...
On the trace image, diffusion is seen to be greatest in the CSF-filled ventricles and sulci, where there is little restriction to diffusion, and lower in tissue.
Mean diffusivity (trace/3) vs fractional anisotropy in leukoaraiosis patients, controls, and patients with infarcts secondary to carotid stenosis.
Diffusion Anisotropy of the Internal Capsule and the Corona Radiata in Association with Stroke and Tumors as Measured by Diffusion-weighted MR Imaging
stroke.ahajournals.org /cgi/content/full/30/2/393   (3917 words)

  
 NIC - Publications
Functional magnetic resonance imaging and evoked potential correlates of conscious and unconscious vision in parietal extinction patients.
Functional magnetic resonance imaging and diffusion tensor imaging in a case of central poststroke pain.
Combination of event-related fMRI and diffusion tensor imaging in an infant with perinatal stroke.
labnic.unige.ch /nic/htms/publication.html   (2434 words)

  
 Whole Brain Diffusion Tensor Imaging in HIV-Associated Cognitive Impairment -- Ragin et al. 25 (2): 195 -- American ...
Whole Brain Diffusion Tensor Imaging in HIV-Associated Cognitive Impairment -- Ragin et al.
tensor imaging indices with respect to severity of cognitive
of diffusion tensor imaging for noninvasive MR imaging measurement
www.ajnr.org /cgi/content/abstract/25/2/195   (313 words)

  
 NIH News Backgrounder--Diffusion Tensor Magnetic Resonance Imaging- - 12/04/2000   (Site not responding. Last check: 2007-10-03)
Diffusion Tensor Magnetic Resonance Imaging, or DT-MRI, is a technology that measures the random motion of hydrogen atoms within water molecules in all three dimensions, non-invasively, and in vivo.
Diffusion causes a drop of a dye that is placed at the center of a beaker of water to slowly spread apart in a spherical pattern.
Water in tissues containing a large number of fibers, like skeletal muscle, cardiac muscle, and brain white matter, diffuse fastest along the direction that the fibers are pointing in, and slowest at right angles to it.
www.nih.gov /news/pr/dec2000/nichd-04.htm   (315 words)

  
 ISMRM Morning Categorical: Diffusion Tensor Imaging
This four-hour course will focus on the rapidly evolving art of diffusion tensor imaging (DTI), highlighting the principles and practices of how and why DTI is performed.
Topics will include the theoretical background of proton diffusion, along with practical methods of how to measure and analyze the diffusion tensor (currently the most commonly used description of the diffusion process).
The course will also include exploration of methods which go behind the simple tensor-based model, such as q-space imaging, diffusion spectrum imaging, and the multi-exponential and/or multi-compartmental aspects of diffusion.
www.ismrm.org /03/morningcat4('03).htm   (182 words)

  
 Multiresolution Morphodynamic Diffusion Tensor Imaging   (Site not responding. Last check: 2007-10-03)
We have proposed and developed a new multiresolution morphological reconstruction approach for diffusion tensor imaging.
Our point of departure is a precise multiresolution statistical interpretation of a three-dimensional variational approach to segmentation that incorporates recursive procedures for computing estimates of inhomogeneous Gaussian Markov random fields.
The diffusion tensor is based on a regularized shape operator of the evolving level sets that preserves geometric features by a multiresolution anisotropic curvature evolution.
www.yorku.ca /tutor/cours/node9.html   (130 words)

  
 White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging -- ...
The grey rectangles represent the mean values (±2 SD) for mean diffusivity and MMSE (A) and for fractional anisotropy and MMSE (B) from the normal controls.
Atrophy of the hippocampus, parietal cortex and insula in Alzheimer's disease: a volumetric magnetic resonance imaging study.
Diffusion and perfusion MR imaging in cases of Alzheimer's disease: correlations with cortical atrophy and lesion load.
jnnp.bmjjournals.com /cgi/content/full/72/6/742   (3595 words)

  
 Evaluation of White Matter Anisotropy in Krabbe Disease with Diffusion Tensor MR Imaging: Initial Experience -- Guo et ...
Diffusion tensor MR imaging was not available prior to treatment.
MR imaging of anisotropically restricted diffusion in the brain of neonates and infants.
Normal brain in human newborns: apparent diffusion coefficient and diffusion anisotropy measured using diffusion tensor MR imaging.
radiology.rsnajnls.org /cgi/content/full/218/3/809   (5161 words)

  
 Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis -- Werring et al. 52 (8): ...
Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis -- Werring et al.
Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis
Diffusion tensor imaging demonstrates deviation of fibres in normal appearing white matter adjacent to a brain tumour
www.neurology.org /cgi/content/abstract/52/8/1626   (2082 words)

  
 Whole Brain Diffusion Tensor Imaging in HIV-Associated Cognitive Impairment -- Ragin et al. 25 (2): 195 -- American ...
MR imaging is limited by the diffuse nature of the neuropathologic
diffusion tensor imaging indices are presented in Table 1.
Diffusion tensor imaging in patients with epilepsy and malformations of cortical development.
www.ajnr.org /cgi/content/full/25/2/195   (3366 words)

  
 Practice parameter: Neuroimaging of the neonate: Report of the Quality Standards Subcommittee of the American Academy ...
Magnetic resonance imaging of the brain in a cohort of extremely preterm infants.
Sonography, CT, and MR imaging: a prospective comparison of neonates with suspected intracranial ischemia and hemorrhage.
Quantitative apparent diffusion coefficient measurements in term neonates for early detection of hypoxic-ischemic brain injury: initial experience.
neurology.org /cgi/content/full/58/12/1726   (7034 words)

  
 Preterm Children Have Disturbances of White Matter at 11 Years of Age as Shown by Diffusion Tensor Imaging -- NAGY et ...   (Site not responding. Last check: 2007-10-03)
From the tensor FA images were calculated (11).
The vector plots are overlaid on the average of the FA images of all subjects (A) or on a color-coded image where, blue, red, and green represent left-right, anterior-posterior, and superior-inferior directions, respectively, on the basis of the three components of the major direction of diffusion in a given voxel (B).
As the arrows represent the direction of water diffusion in a given voxel and water tends to diffuse along white matter fibers, this coherence measure in effect measures how well white matter fibers are organized in the brain.
www.pedresearch.org /cgi/content/full/54/5/672   (4816 words)

  
 Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging -- ...
Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging -- Scollan et al.
Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging
Diffusion tensor magnetic resonance imaging (MRI) is a possible new means of elucidating the anatomic structure of the myocardium.
ajpheart.physiology.org /cgi/content/abstract/275/6/H2308   (463 words)

  
 Ventricular myocardial architecture as visualised in postmortem swine hearts using magnetic resonance diffusion tensor ...
Ventricular myocardial architecture as visualised in postmortem swine hearts using magnetic resonance diffusion tensor imaging -- Schmid et al.
Ventricular myocardial architecture as visualised in postmortem swine hearts using magnetic resonance diffusion tensor imaging
We calculated the diffusion tensor and the corresponding
ejcts.ctsnetjournals.org /cgi/content/abstract/27/3/468   (376 words)

  
 Arch Neurol -- Abstract: Assessment of Normal-Appearing White and Gray Matter in Patients With Primary Progressive ...   (Site not responding. Last check: 2007-10-03)
Arch Neurol -- Abstract: Assessment of Normal-Appearing White and Gray Matter in Patients With Primary Progressive Multiple Sclerosis: A Diffusion-Tensor Magnetic Resonance Imaging Study, September 2002, Rovaris et al.
Average diffusivity values were significantly higher in patients
Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI
archneur.ama-assn.org /cgi/content/abstract/59/9/1406   (475 words)

  
 Department of Radiology: Physician's Directory
Magnetic resonance imaging, MRI, MR imaging of brain development, diffusion tensor imaging, perfusion MR imaging and functional MR imaging, functional neuroimaging with magnetic resonance
A prospective longitudinal diffusion tensor imaging study of brain injury in newborns.
Differences in water diffusion between gray matter and white matter in stroke: Diffusion tensor MR imaging experience in twelve patients.
www.wuphysicians.wustl.edu /physician2.asp?PhysNum=2720   (602 words)

  
 Imaging of Alzheimer's Disease -- Lee et al. 13 (3): 199 -- Journal of Neuroimaging
Imaging of Alzheimer's Disease -- Lee et al.
Imaging is widely used in the evaluation of Alzheimer's disease
and functional imaging are being explored for potential use
jon.sagepub.com /cgi/content/abstract/13/3/199   (327 words)

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