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| | Compounded Percutaneous Testosterone Gel: Use And Effects in Hypogonadal Men |
 | | Patients were withdrawn from their previous hormone therapy (where applicable), and baseline laboratory studies were obtained for total testosterone, free testosterone, dihydrotestosterone, estradiol, luteinizing hormone, follicle-stimulating hormone, complete blood counts, lipid panels, and chemistry panels. |
 | | The supraphysiologic levels of dihydrotestosterone occurred in all patients who applied all or part of the gel to the scrotal and thigh area (patients 1,2,3,4,8,9, and 10). |
 | | In this study, amounts as small as 15 mg and as much as 120 mg of topically applied testosterone gel were required to reach physiologic levels of testosterone, dihydrotestosterone, and estradiol, which implies an absorption efficiency of anywhere from 50% to as low as 6%. |
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