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Delivery system for suncare products - Patent 6074630 Dihydroxyacetone is an acceptable skin tanning agent to be utilized in the invention of Lentini et al. The color intensity produced by dihydroxyacetone on the skin is dependent on two factors: the amount and/or type of amine reactor sites per unit area available to react with the dihydroxyacetone, and the amount of dihydroxyacetone per unit area applied. In contrast, by using a cloth or pad matrix the amount of color that develops on the skin is controlled by two factors: the concentration of dihydroxyacetone in the solution, which is typically 15 to 60% w/w in water, and the relative affinity for the dihydroxyacetone solution between the cloth or pad and untreated skin. www.freepatentsonline.com /6074630.html   (7788 words)

Dihydroxyacetone - Wikipedia, the free encyclopedia Dihydroxyacetone (also known as DHA) is a simple carbohydrate that is primarily used as an ingredient in sunless tanning products. It is often derived from plant sources such as sugar beets and sugar cane, by the fermentation of glycerin. DHA may be prepared, along with glyceraldehyde, by the mild oxidation of glycerol, for example with hydrogen peroxide and a ferrous salt as catalyst. en.wikipedia.org /wiki/Dihydroxyacetone   (1001 words)

Code of Federal Regulations: 21 CFR 73.1150 - Dihydroxyacetone   (Site not responding. Last check: 2007-11-02) Dihydroxyacetone shall conform to the following specifications and shall be free from impurities other than those named to the extent that such impurities may be avoided by good manufacturing practice: Volatile matter (at 34.6 deg.C. for 3 hours at a pressure of not more than 30 mm. Dihydroxyacetone may be safely used in amounts consistent with good manufacturing practice in externally applied drugs intended solely or in part to impart a color to the human body. Certification of this color additive is not necessary for the protection of the public health and therefore batches thereof are exempt from the certification requirements of section 721(c) of the act. www.cfsan.fda.gov /~lrd/cf731150.html   (361 words)

Cosmetic compositions containing dihydroxyacetone and methods of stabilizing the same - Patent 6348202 Accordingly, the problem addressed by the present invention was to provide cosmetic preparations containing dihydroxyacetone which would be simultaneously distinguished by high dermatological compatibility, a favorable feeling on the skin and, in particular, by high stability in storage at relatively high temperatures. It has surprisingly been found that cosmetic preparations containing dihydroxyacetone which are distinguished by excellent stability in storage, even at elevated temperatures, can be obtained by using mixtures of alkyl and/or alkenyl oligoglycosides and polyol poly-12-hydroxystearates as nonionic emulsifiers. One preferred embodiment of the invention is characterized by the use of mixtures containing (a) alkyl oligoglucosides and (b) polyglycerol poly-12-hydroxystearates in a ratio by weight of 25:75 to 75:25 and preferably in a ratio by weight of 40:60 to 60:40 and, in addition a polyol, preferably glycerol. www.freepatentsonline.com /6348202.html   (3351 words)

Dihydroxyacetone.   (Site not responding. Last check: 2007-11-02) Dihydroxyacetone - also known as DHA is the active ingredient in most good quality self-tan or instant tan products. It is a colorless compound composed of 3-carbon sugars and causes a chemical reaction with the amino acids contained in the surface cells of the skin, which then develops and cause a darkening, or tanned, effect. Dihydroxyacetone does not cause any damage to the skin, as it only interacts with the stratum corneum - the horny layer of the skin. www.dermaxime.com /dihydroxyacetone.htm   (281 words)

Bulk Nutrition - Pyruvate for Fatloss by David Tolson   (Site not responding. Last check: 2007-11-02) Pyruvate is a three-carbon compound that occurs naturally in the body and is generated by the breakdown of glucose (glycolysis) and the catabolism of amino acids. He first found that when pyruvate and dihydroxyacetone were added to the diets of rats and swine, there was a significant reduction in body fat without any reduction in body protein or muscle content [1-2], and this effect has been confirmed in multiple studies since then [3-5]. This was followed by two clinical trials in which high doses of pyruvate and dihydroxyacetone (totaling 33-100 grams and containing 19-44 grams of pyruvate) enhanced fat loss without effecting nitrogen balance in subjects on low or very low calorie diets. www.bulknutrition.com /i22_Pyruvate.html   (1282 words)

Boosting Exercise Performance with Pyruvate and Dihydroxyacetone: Nov 1997 Dihydroxyacetone is a product of the metabolism of glucose and glycerol. Then in the early 1980s, glucose polymer drinks (long chains of sugar molecules that stay connected in solution) were marketed as a way to replace glycogen stores without the added bulk of whole grains in the intestinal tract. Early studies used 100 g of DHAP as a mixture of 25 g pyruvate and 75 g dihydroxyacetone. www.vitamintrader.com /articles/1997_11_Pyruvate.html   (1471 words)

Dihydroxyacetone - the active ingredient in self tan Dihydroxyacetone (DHA) is a simple three-carbon sugar, non-toxic in nature which has received approval by the FDA. The use of dihydroxyacetone in the cosmetics industry came about from one woman's devotion to treating children suffering from glycogen storage disorders. Eva Wittgenstein was using DHA as the treatment and noticed that on contact with the skin the concentrate produced brown spots. www.pinkfridge.com /hab_tanning/dihydroxyacetone.htm   (363 words)

ThirdAge: Pyruvate Dihydroxyacetone dosages in studies of DHAP (pyruvate plus dihydroxyacetone) have ranged from 12 to 75 g daily. Both pyruvate and dihydroxyacetone appear to be quite safe, aside from mild side effects such as occasional stomach upset and diarrhea. Effect of pyruvate and dihydroxyacetone on metabolism and aerobic endurance capacity. www.thirdage.com /healthgate/files/21633.html   (1148 words)

Code of Federal Regulations: 21 CFR 73.2150 - Dihydroxyacetone   (Site not responding. Last check: 2007-11-02) The color additive dihydroxyacetone shall conform in identity and specifications to the requirements of Sec. Dihydroxyacetone may be safely used in amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in part to impart a color to the human body. Certification of this color additive is not necessary for the protection of the public health and therefore batches thereof are exempt from the requirements of section 721(c) of the act. www.cfsan.fda.gov /~lrd/cf732150.html   (218 words)

Imitation Tanners When you apply a sunless tanning product with dihydroxyacetone on your skin, it reacts with the amino acids in the epidermis of the skin and produces color. Dihydroxyacetone is the only ingredient approved by the US FDA for sunless tanning. Note that the tanned skin with dihydroxyacetone is not safe from sun. www.doctorgoodskin.com /pd/imitationtanners   (390 words)

Glucose 6-Phosphate Regulates Hepatic Glycogenolysis Through Inactivation of Phosphorylase -- Aiston et al. 52 (6): ... and incubation with octanoate or dihydroxyacetone, cause inactivation Octanoate and dihydroxyacetone inactivate phosphorylase and increase G6P. by octanoate and dihydroxyacetone is evidence for a physiological diabetes.diabetesjournals.org /cgi/content/full/52/6/1333   (3990 words)

Fluorescence spectral imaging of dihydroxyacetone on skin in vivo[para] Photochemistry and Photobiology - Find Articles Dihydroxyacetone (DHA) has been proposed as a potential alternative to dansyl chloride for use as a fluorescence marker on skin to assess stratum corneum turnover time in vivo. Abbreviations: CCD, charge-coupled device; DC, dansyl chloride; DHA, dihydroxyacetone; DHA-SC, DHA-skin complex; LCTF, liquid crystal tunable filter; OD, optical density; OTC, over-the-counter; ROI, region of interest; UVA, ultraviolet radiation in the 320-400 nm wavelength region. Two recent proposals for the replacement of DC include application of henna stains with optothermal detection (12) and application of dihydroxyacetone (DHA) with colorimetric measurements (10). findarticles.com /p/articles/mi_qa3931/is_200305/ai_n9299308   (860 words)

Oxidative Phosphorylation--Electron Shuttles In the cytoplasm, dihydroxyacetone phosphate is converted to glycerol 3-phosphate by the enzyme glyceraldehyde 3-phosphate. Glycerol 3-phosphate can readily cross the outer mitochondrial membrane and so it diffuses into the mitochondria where it is then reduced to dihydroxyacetone phosphate with the transfer of electrons to an FAD containing enzyme. Dihydroxyacetone phosphate then diffuses back into the cytoplasm. www.dentistry.leeds.ac.uk /biochem/uttb/OXPHOS4.HTM   (915 words)

University of Berne, Biochemistry, Membrane, Protein, Dihydroxyacetone, Kinase The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) mediates the uptake and phosphorylation of carbohydrates, and is involved in signal trans­duc­tion (PM In response to the availability of carbohydrates it modulates catabolite repression, intermediate metabolism, gene expression and chemotaxis. A high resolution structure of a membrane protein catalyzing the vectorial transport of a substrate coupled to the transfer of a chemical group might reveal new insights into the structure and function of a membrane embedded protein (flexibility, induced fit to large substrate). Dihydroxyacetone is an important educt for large scale aldolase-catalyzed synthetic reactions. www.dcb.unibe.ch /groups/erni/research.html   (300 words)

Spray-on tanning catching on as a safer alternative - Minnesota Daily A June 2003 Food and Drug Administration report states dihydroxyacetone should not be inhaled or come in contact with eyes and the mouth. Amy Johnson, public affairs specialist at the FDA's Minneapolis district office, said studies are inconclusive on the effects dihydroxyacetone has on internal ingestion, but it has only been approved for external use. "Dihydroxyacetone has been used as a diet supplement in sports nutrition and is noncarcinogenic," a Mystic Tan pamphlet states. www.mndaily.com /articles/2004/04/26/9429   (553 words)

Sunless Tanning Products: Dihydroxyacetone, Sunless Tanning Lotion The FDA approved the main ingredient, Dihydroxyacetone (DHA) found in sunless tanning products to be safe for external applications 30 years ago. Our sunless tanning products contain a blend of Dihydroxyacetone, Erythrulose, essential oils and a powerful blend of vitamins; providing a rich, long lasting tan that revitalizes and hydrates the skin. DHA (Dihydroxyacetone) causes a chemical reaction that takes place on the outer layers of the epidermis and reacts with amino acids of the skin's keratin forming brown colored compounds. www.mist-it-tan.com /products.htm   (418 words)

Regulation and Physiological Role of the DAS1 Gene, Encoding Dihydroxyacetone Synthase, in the Methylotrophic Yeast ... The physiological role of dihydroxyacetone synthase (DHAS) in Candida boidinii was evaluated at the molecular level. Classical transketolase functions as the formaldehyde-assimilating enzyme during growth of a dihydroxyacetone synthase-negative mutant of the methylotrophic yeast Hansenula polymorpha on mixtures of xylose and methanol in continuous culture. Molin, M., Norbeck, J., Blomberg, A. Dihydroxyacetone Kinases in Saccharomyces cerevisiae Are Involved in Detoxification of Dihydroxyacetone. jb.asm.org /cgi/content/full/180/22/5885   (3389 words)

Dihydroxyacetone phosphate - Wikipedia, the free encyclopedia Dihydroxyacetone phosphate (DHAP) is a biochemical compound involved in many reactions, from the Calvin cycle in plants to the ether-lipid biosynthesis process in Leishmania mexicana. DHAP may be referred to as glycerone phosphate in older texts. Dihydroxyacetone phosphate lies in the glycolysis metabolic pathway, and is one of the two products of breakdown of fructose 1,6-phosphate, along with glyceraldehyde 3-phosphate. en.wikipedia.org /wiki/DHAP   (251 words)

Sunless Tanning: Facts And Myths - Sunless.com The drive some people have to get a tan is as powerful and all-consuming as the impulse of others to lose weight fast, thicken thinning hair, and restore failing virility. The purpose of this article is to examine what sunless tanning alternatives exist now, what may exist in the future, and what should never have existed at all. If there is a safe and effective alternative to dihydroxyacetone, the active ingredient in all sunless tanners, you will find out about it here. www.sunless.com /safe/melanotan.php   (286 words)

Article: Tan Lines   (Site not responding. Last check: 2007-11-02) Its name, dihydroxyacetone or DHA, may sound intimidating but it’s a benign agent that has been refined to the point of perfection. More stable forms of dihydroxyacetone were eventually developed, addressing the problem of orange coloring. One shortcoming of a sunless tan is the unevenness of color that typically arises when people manually apply dihydroxyacetone to their skin. umanitoba.fitdv.com /new/articles/article.html?artid=693   (702 words)

Pyruvate Another interesting placebo-controlled study evaluated the effects of combined dihydroxyacetone and pyruvate (DHAP) when individuals who had previously lost weight increased their calorie intake. While all these studies are intriguing, we really need large studies (100 participants or more) to establish the benefits of pyruvate for weight loss. However, maximum safe dosages for children, women who are pregnant or nursing, or those with liver or kidney disease have not been established. www.al-hikmah.org /pyruvate.asp   (1009 words)

Frequently Asked Questions - Sunless.com Sunless tanners contain dihydroxyacetone [DHA] which reacts with the amino acids in the top [or "dead"] layer of your skin. The concern some doctors have is over whether or not the active ingredient, dihydroxyacetone or DHA, is able to penetrate the skin. The FDA frowns upon all other means of producing a tan without the sun, including tanning pills, which contain carotenoid color additives, and tanning "accelerators" which contain tyrosine or tyrosine derivatives. www.sunless.com /help/faq.php   (2332 words)

Aruba Tan Airbrush Tanning Systems - How DHA Gives a Tan - Consumer Site Many of these products take 45 minutes to one hour to start taking effect, and once you factor in drying time, you could be looking at about three hours spent achieving that sun-free tan. According to the American Academy of Dermatology, the most effective products available are sunless- or self-tanning lotions that contain dihydroxyacetone (DHA) as the active ingredient. DHA is a colorless sugar that interacts with the dead cells located in the stratum corneum of the epidermis. www.arubatan.com /consumers/c_howdhaworks.html   (688 words)

Dr. Hale's Breastfeeding and Medications Forum: Sunless tanning lotion and breastfeeding 2) The degree to which dihydroxyacetone is absorbed into the body from the I too tried to find some toxicology data on dihydroxyacetone and was unable to find anything other than "irritant". Thus I would not be overly worried about a breastfeeding infant were the mom to use these products. neonatal.ama.ttuhsc.edu /discus/messages/53/456.html?1058466337   (445 words)

Airbrush Tanning provided by Suddenly Younger and Slimmer of Los Alamitos, California   (Site not responding. Last check: 2007-11-02) Very simply, the DHA (dihydroxyacetone), reacts with the amino acids (proteins) in the outermost layer of your skin. The active ingredient is dihydroxyacetone and has been approved by the FDA for cosmetic applications. The balance of the spray is composed of inert carrying agents. www.visualedgedesign.com /bodywrap/losalamitos/tanning.htm   (604 words)

Facile syntheses of acyl dihydroxyacetone phosphates and lysophosphatidic acids having different acyl groups -- Das et ... Facile syntheses of acyl dihydroxyacetone phosphates and lysophosphatidic acids having different acyl groups -- Das et al. Facile syntheses of acyl dihydroxyacetone phosphates and lysophosphatidic acids having different acyl groups of acyl dihydroxyacetone phosphate (DHAP) and 1-acyl glycero-3-phosphate www.jlr.org /cgi/content/abstract/47/8/1874   (336 words)

Leishmania major Expresses a Single Dihydroxyacetone Phosphate Acyltransferase Localized in the Glycosome, Important ... Leishmania major Expresses a Single Dihydroxyacetone Phosphate Acyltransferase Localized in the Glycosome, Important for Rapid Growth and Survival at High Cell Density and Essential for Virulence -- Zufferey and Mamoun 281 (12): 7952 -- Journal of Biological Chemistry Articles by Zufferey, R. Articles by Mamoun, C. Leishmania major Expresses a Single Dihydroxyacetone Phosphate Acyltransferase Localized in the Glycosome, Important for Rapid Growth and Survival at High Cell Density and Essential for Virulence From the Department of Genetics and Developmental Biology and the Department of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, Farmington, Connecticut 06030-3301 www.jbc.org /cgi/content/abstract/281/12/7952   (379 words)

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