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Topic: Dipyridamole


  
  Anti-Cancer Effect of Dipyridamole - Second Opinions
Reference is also given that dipyridamole tends to prevent this attachment of cancer cells flowing in the blood circulation to the endothelium and thus tends to prevent the formation of metastases.
She treated melanoma with dipyridamole because she is a dermatologist and that is the kind of cancer that she treated.
Dipyridamole, by preventing the formation of the white or platelet thrombus, will also be preventing the formation of a fibrin thrombus.
www.second-opinions.co.uk /dipyridamole.html   (1310 words)

  
  Dipyridamole - Wikipedia, the free encyclopedia
Dipyridamole is a drug that inhibits platelet aggregation and causes vasodilation.
Modified release dipyridamole is used in conjunction with aspirin (under the trade name Aggrenox®) in the secondary prevention of stroke and transient ischemic attack.
Dipyridamole is also used in nuclear cardiac stress testing as a coronary vasodilator.
en.wikipedia.org /wiki/Dipyridamole   (236 words)

  
 Atlas of Myocardial Perfusion SPECT: dipyridamole.html
Dipyridamole was the first pharmacological stress test agent introduced in the early 80-ties, it was initially administered as capsules (with many GI side effects) and later as IV infusion.
Dipyridamole inhibits the normal faciliated re-absorption of natural vasodilator Adenosine, which is synthesized and released from endothelial cells as part of local vaso-regulatory systems.
Dipyridamole thus leads to increased amount of extra-cellular Adenosine available to react with Adenosine receptors, stimulation of which leads to vascular smooth muscle cell relaxation and therefore coronary vasodilation (increased flow).
brighamrad.harvard.edu /education/online/Cardiac/dipyridamole.htm   (191 words)

  
 Dipyridamole
Dipyridamole (dye-peer-ID-a-mole) is used to lessen the chance of stroke or other serious medical problems that may occur when a blood vessel is blocked by blood clots.
Dipyridamole may also be used for other heart and blood conditions as determined by your doctor.
Dipyridamole is also sometimes used as part of a medical test that shows how well blood is flowing to your heart.
www.healthtouch.com /bin/EContent_HT/drugShowLfts.asp?fname=usp0659.htm&title=Dipyridamole&cid=HT   (1218 words)

  
 dipyridamole - Drug Finder - MSN Health & Fitness   (Site not responding. Last check: 2007-11-07)
Dipyridamole stops platelets (substances in your blood necessary for blood clotting) from sticking together or attaching to prosthetic heart valve surfaces.
Dipyridamole is used to prevent the formation of blood clots following heart valve replacement surgery.
Dipyridamole is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100059802   (1031 words)

  
 dipyridamole - Connecticut
Dipyridamole stops platelets (substances in your blood necessary for blood clotting) from sticking together or attaching to prosthetic heart valve surfaces.
Dipyridamole is used to prevent the formation of blood clots following heart valve replacement surgery.
Dipyridamole is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
www.saintfranciscare.com /18687.cfm   (936 words)

  
 Dipyridamole news articles   (Site not responding. Last check: 2007-11-07)
During pharmacologic stress with dipyridamole or adenosine stress, coronary vessels respond with an endothelial-mediated and smooth muscle-mediated vasodilation...
Dipyridamole, a non-nitrate coronary vasodilator that also inhibits platelet aggregation, is combined with other anticoagulant drugs, such as warfarin, to prevent thrombosis in patients with valvular or vascular disorders.
Dipyridamole is also used in myocardial perfusion imaging, as an antiplatelet agent, and in combination with aspirin for stroke prophylaxis.
www.mongabay.com /drugs/drugs/Dipyridamole.html   (892 words)

  
 Dipyridamole inhibits sickling-induced cation fluxes in sickle red blood cells -- Joiner et al. 97 (12): 3976 -- Blood
Dipyridamole was measured in HBS by fluorescence at 480 nm with excitation at 293 nm in a fluorescence spectrometer (Model
For quantification of dipyridamole, the difference between peak fluorescence at 293 nm and minimum fluorescence at 265 nm was calculated (depicted in panel B).
Dipyridamole fluorescence at 480 nm with excitation at 293 nm was assayed in supernatants of 2% RBC suspensions after the addition of the indicated concentrations of drug.
www.bloodjournal.org /cgi/content/full/97/12/3976   (5297 words)

  
 MedlinePlus Drug Information: Dipyridamole
Dipyridamole is used with other drugs to reduce the risk of blood clots after heart valve replacement.
Dipyridamole comes as a tablet to take by mouth.
Dipyridamole is also used with aspirin to reduce the risk of death after a heart attack and to prevent another heart attack.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682830.html   (548 words)

  
 Persantin
Dipyridamole is also given to people who have experienced a stroke or a mini-stroke (transient ischaemic attack) caused by a clot reducing the blood flow to parts of the brain.
Dipyridamole is used to prevent the formation of further blood clots that could cause another stroke.
If you are taking dipyridamole regularly by mouth you should not be given an additional dose of dipyridamole by injection, unless your doctor feels it will be necessary for a heart test, in which case you should be asked to stop taking your oral dipyridamole 24 hours before the test.
www.netdoctor.co.uk /medicines/100002047.html   (1228 words)

  
 Vascular disease - clopidogrel and dipyridamole
Thereafter, or if MR dipyridamole is not tolerated, preventative therapy should revert to standard care (including long-term treatment with low-dose aspirin) 1.1.2 clopidogrel alone (within its licensed indications) is recommended for people who are intolerant of low-dose aspirin and either have experienced an occlusive vascular event or have symptomatic peripheral arterial disease.
This guidance refers to the modified-release (MR) formulation of dipyridamole only, which is licensed for the secondary prevention of ischaemic stroke and TIAs, either alone (Persantin Retard, 200 mg dipyridamole twice daily) or in combination with aspirin (Asasantin Retard, 200 mg dipyridamole plus 25 mg aspirin twice daily).
Given that any differences in the effects of clopidogrel and MR dipyridamole on non-vascular mortality seen in clinical trials are small, uncertain and based on indirect comparisons, the Committee concluded that the exclusion of the RR for non- vascular death is advisable for the modelling of lifetime treatment.
www.tripdatabase.com /spider.html?itemid=250054   (6772 words)

  
 Appraisal Consultation Document: Clopidogrel and modified-release dipyridamole in the secondary prevention of occlusive ...
Dipyridamole (Boehringer Ingelheim) has both antiplatelet and vasodilating properties and is thought to inhibit the uptake of adenosine (a potent inhibitor of platelet activation and aggregation) into blood and vascular cells.
The frequency of bleeding complications was significantly lower with MR dipyridamole (4.7%) than with aspirin (8.2%), and similar in the aspirin/MR dipyridamole (8.7%) and the aspirin (8.2%) groups.
Based on the evidence available for dipyridamole on effectiveness on stroke and on the modest cost per QALY, the Committee concluded that 2-year treatment with MR dipyridamole in combination with aspirin is recommended for the prevention of recurrent events in people who have had a stroke or TIA.
www.nice.org.uk /article.asp?a=105159   (5825 words)

  
 dipyridamole Side Effects, Interactions and Information - Drugs.com
Dipyridamole keeps the platelets in your blood from coagulating (clotting) to prevent blood clots from forming on or around an artificial heart valve.
Dipyridamole is used to prevent blood clots after heart valve replacement surgery.
Dipyridamole is often taken together with other medications to prevent blood clots.
www.drugs.com /MTM/dipyridamole.html   (1338 words)

  
 Dipyridamole - Patient UK
Dipyridamole reduces the stickiness of these platelets, therefore thinning the blood slightly and helping to prevent unwanted blood clots from forming within the body.
Dipyridamole is particularly useful for patients who have had surgery to replace heart valves as it allows the blood to move around the body and through the new valves more easily.
Dipyridamole is also used for patients who have previously had certain types of strokes or suffer from transient ischaemic attacks (attacks in which the blood vessels in the brain become narrow, temporarily cutting off the blood supply).
www.patient.co.uk /showdoc/30002141   (1062 words)

  
 Order PERSANTINE @ Rx Care Canada
The incidence of thromboembolic events in patients receiving dipyridamole in a dose of 400 mg/day in combination with anticoagulants was 1.3% compared to 14.3% to the control group treated with anticoagulant alone.
Dipyridamole is a coronary vasodilator in man. The mechanism of vasodilation has not been fully elucidated, but may result from inhibition of uptake of adenosine, an important mediator of coronary vasodilation.
I.V. dipyridamole as an adjunct to myocardial perfusion imaging should be used with caution in patients with unstable angina, as such patients may be at risk for severe myocardial infarction.
canadapharmacy.rxcarecanada.com /PERSANTINE.asp?prodid=PERSANTINE   (2205 words)

  
 aspirin and dipyridamole - [Medication]
Aspirin and dipyridamole is used to reduce the risk of stroke by preventing the formation of blood clots in patients who have had transient ischemic attacks (TIA or "mini-stroke") or ischemic stroke due to thrombosis.
Aspirin and dipyridamole is in the FDA pregnancy category D. This means that it is known to harm an unborn baby.
Symptoms of an aspirin and dipyridamole overdose include a warm feeling, flushes, sweating, restlessness, feeling of weakness, dizziness, ringing in the ears, blurred vision, a drop in blood pressure, and a rapid or irregular heart beat.
www.peacehealth.org /kbase/multum/d04497a1.htm   (1450 words)

  
 Dipyridamole, Permole, Persantine
Dipyridamole prevents platelet clumping and is used with
Controlled research is needed to determine whether taking garlic supplements together with dipyridamole might enhance the effectiveness of either compound taken alone.
Taking dipyridamole can cause a reduction in the amount of oxygen delivered to the heart, resulting in a rare side effect known as angina pectoris.
www.truestarhealth.com /Notes/1358008.html   (569 words)

  
 Persantine (Dipyridamole) drug description - prescription drugs and medications at RxList
(dipyridamole USP) is a platelet inhibitor chemically described as 2,2',2",2'" -[(4,8-Dipiperidinopyrimido[5,4- d ]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol.
Dipyridamole is an odorless-yellow crystalline powder, having a bitter taste.
It is soluble in dilute acids, methanol and chloroform, and practically insoluble in water.
www.rxlist.com /cgi/generic/dipyrid.htm   (168 words)

  
 Dipyridamole
Dipyridamole is used with other medicines to prevent blood clots and problems such as stroke.
Dipyridamole comes in tablets and is usually taken three or four times a day.
Dipyridamole must be taken regularly to be effective.
www.clevelandclinic.org /health/health-info/docs/0600/0680.asp?index=4822   (638 words)

  
 Dipyridamole
Dipyridamole prevents platelet clumping and is used with warfarin (Coumadin®) to prevent blood clots from forming after heart valve replacement.
Controlled research is needed to determine whether taking garlic supplements together with dipyridamole might enhance the effectiveness of either compound taken alone.
Taking dipyridamole can cause a reduction in the amount of oxygen delivered to the heart, resulting in a rare side effect known as angina pectoris.
www.pccnaturalmarkets.com /health/Drug/Dipyridamole.htm   (559 words)

  
 Montefiore Professionals: Dipyridamole Cardiac Stress Imaging
The Dipyridamole Cardiac Stress Imaging test is designed to determine if there are any blockages in your coronary arteries, how severe they may be, and if there has been any damage to your heart from blockages in your arteries.
The electrodes allow us to closely watch your heart rate and electrocardiogram during the test.  An intravenous line (IV) will be placed in your arm so that we can inject the radioisotope compound (thallium or sestamibi) and the necessary medications into your blood stream.
Dipyridamole will be infused through the IV for approximately 4 minutes.
www.montefiore.org /prof/departments/nuclear/services/dipyridamole   (748 words)

  
 Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial ...
Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial infarction -- Hung et al.
Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial infarction
A dipyridamole induced reversible thallium-201 perfusion defect occurred in 123 patients (62%) in the study cohort.
heart.bmjjournals.com /cgi/content/full/78/4/346   (3993 words)

  
 Urodilatin, a Natriuretic Peptide Stimulating Particulate Guanylate Cyclase, and the Phosphodiesterase 5 Inhibitor ...
Urodilatin, a Natriuretic Peptide Stimulating Particulate Guanylate Cyclase, and the Phosphodiesterase 5 Inhibitor Dipyridamole Attenuate Experimental Pulmonary Hypertension.
After stable pressure plateau, dipyridamole was applied in different doses as a short-term infusion (10 min) or short-term inhalation (10 min) in incremental doses (intravenous: 2, 10, and 20 µg/kg min; inhaled: 0.1, 1, and 10 µg/kg min).
Dipyridamole was applied 15 min before urodilatin as a short-term infusion (10 min) or inhalation (10 min).
ajrcmb.atsjournals.org /cgi/content/full/25/2/219   (4108 words)

  
 What is the role of dipyridamole in long-term secondary prevention after an ischemic stroke or transient ischemic ...
of clopidogrel and modified-release dipyridamole in the secondary
Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke.
Dipyridamole for preventing recurrent ischemic stroke and other vascular events: a meta-analysis of individual patient data from randomized controlled trials [review].
www.cmaj.ca /cgi/content/full/173/9/1024   (1661 words)

  
 Long-Term Inhaled Nitric Oxide plus Dipyridamole for Pulmonary Arterial Hypertension
An inhibitor of phosphodiesterase type 5 (dipyridamole) was added during the second year to ameliorate the rebound of symptoms.
The evidence indicates that dipyridamole such as sildenafil enhances the vasodilator effects of iNO increasing the intracellular levels of cGMP by inhibition of the phosphodiesterase type 5 enzyme [10].
Although dipyridamole has been used in newborn pulmonary hypertension to wean from iNO and to improve the response to this gas, it has never been administered on a long-term basis in adults with PAH [10].
content.karger.com /ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=86258&Ausgabe=231167&ProduktNr=224278   (2315 words)

  
 CIGNA - aspirin and dipyridamole
The combination of aspirin and dipyridamole is used to reduce the risk of stroke in people who have had blood clots or a "mini-stroke" (also called a transient ischemic attack or TIA).
If you have any of these conditions, you may not be able to take aspirin and dipyridamole, or you may need a dosage adjustment or special tests during treatment.
Symptoms of an aspirin and dipyridamole overdose may include warmth or tingly feeling, sweating, restlessness, dizziness, weakness, feeling light-headed, or fainting.
www.cigna.com /healthinfo/d04497a1.html   (1656 words)

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