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Definition of disaccharide - Merriam-Webster Online Dictionary Learn more about "disaccharide" and related topics at Britannica.com Find more about "disaccharide" instantly with Live Search See a map of "disaccharide" in the Visual Thesaurus www.m-w.com /cgi-bin/dictionary?book=Dictionary&va=disaccharide   (41 words)

Disaccharide - Wikipedia, the free encyclopedia A disaccharide is a sugar (a carbohydrate) composed of two monosaccharides. So, even if both component sugars are the same (e.g., glucose), different bond combinations result in disaccharides with different chemical and physical properties. Depending on the monosaccharide constituents, disaccharides are sometimes crystalline, sometimes water-soluble, and sometimes sweet-tasting. en.wikipedia.org /wiki/Disaccharide   (189 words)

[No title] The disaccharide composed of glucose and fructose is known as: a.sucrose. Lactose is a disaccharide: a.composed of glucose and fructose and found in sugar cane. The disaccharide composed of glucose and galactose is known as: a.sucrose. wiz2.pharm.wayne.edu /biochem/carboreview.doc   (3264 words)

[No title]   (Site not responding. Last check: 2007-10-17) The disaccharide includes cellobiuronic acid, and the cellobiuronic acid is present in the hydrolysate at a concentration of at least 5 wt% based on the total weight of polysaccharide. Thus, gellan as used in the present invention is a polysaccharide that incorporates repeating residues derived from the disaccharide cellobiuronic acid or derivatives of cellobiuronic acid such as acetylated cellobiuronic acid or esterified cellobiuronic acid. The total of the monosaccharides and disaccharides in the hydrolysate after the partial hydrolysis is preferably at least 50 wt%, more preferably at least 70 wt%, and still more preferably at least a 90 wt%, based on the total weight of the saccharides in the hydrolysate. www.wipo.int /cgi-pct/guest/getbykey5?KEY=00/08039.000217&ELEMENT_SET=DECL   (7509 words)

Sulfation of Chondroitin Sulfate in Human Articular Cartilage. THE EFFECT OF AGE, TOPOGRAPHICAL POSITION, AND ZONE OF ... The disaccharides of chondroitin sulfate released by digestion of the tissues with chondroitin ABC lyase were analyzed by capillary electrophoresis. S]sulfate and the disaccharide composition of the endogenous and The disaccharides released from the endogenous glycosaminoglycan chains, by the action of chondroitin ABC lyase, were determined by capillary electrophoresis using an UV monitor. www.jbc.org /cgi/content/full/274/22/15892   (5829 words)

Carbohydrates   (Site not responding. Last check: 2007-10-17) The more complex carbohydrates such as disaccharides and polysaccharides are composed of monosaccharides (usually glucose) bonded together in sequence. A disaccharide consisting of one glucose monomer and one galactose monomer. A disaccharide composed of a glucose monomer and a fructose monomer. www.mansfield.ohio-state.edu /~sabedon/biol1025.htm   (1257 words)

Patent 6,656,920   (Site not responding. Last check: 2007-10-17) The disaccharide can also be administered in combination with an effective amount of vitamin C, or a derivative thereof, such as a vitamin C ester. The invention is also directed to a pharmaceutical composition comprising a disaccharide in combination with vitamin C, or a derivative thereof, such as a vitamin C ester. The ratio of disaccharide to vitamin C, or a derivative thereof, in the dosage form is about 10 to 1 to about 1 to 10, more typically about 4 to 1 to about 1 to 4. www.pharmcast.com /Patents100/Yr2003/Dec2003/120203/6656920_Oral120203.htm   (3877 words)

disaccharide Sucrose, an important disaccharide (double sugar) is a polymer of glucose and fructose and is easily recognizable to most of us as common table sugar. Found naturally in mushrooms, honey, lobster and shrimp, the sweetener is a non-reducing disaccharide composed of two glucose molecules linked by an a 1-1 bond... Each apparently has a disaccharide backbone that was acylated at 2, 3, 2', and 3' positions by 3-hydroxy fatty acids. www.mongabay.com /igapo/biotech/disaccharide.html   (149 words)

Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of ... Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase -- Baizman et al. examined in the presence of the disaccharide analogues. the moenomycin disaccharide by the substitution of a nitrogen mic.sgmjournals.org /cgi/content/full/146/12/3129   (4652 words)

Lactose - Wikipedia, the free encyclopedia Lactose is a disaccharide that makes up around 2-8% of the solids in milk. The name comes from the Latin word for milk, plus the -ose ending used to name sugars. Lactose is a disaccharide consisting of two subunits, a galactose and a glucose linked together. en.wikipedia.org /wiki/Lactose   (277 words)

Disaccharide Intolerance I It is possible that the main title of the report Disaccharide Intolerance I is not the name you expected. Disaccharide intolerance I is a rare inherited metabolic disorder characterized by the deficiency or absence of the enzymes sucrase and isomaltase. Disaccharide intolerance I is inherited as an autosomal recessive genetic trait. www.webmd.com /hw/parenting_news/nord626.asp   (516 words)

Media Portfolio As an example, the disaccharide sucrose (table sugar) is broken into glucose and fructose during digestion. Structures (a) and (b) are monosaccharides; (d) is a disaccharide. carbohydrate, monosaccharide, aldehyde, ketone, glycoside linkage, disaccharide, polysaccharide wps.prenhall.com /wps/media/objects/476/488316/ch19.html   (3106 words)

ARS | Publication request: Hf/6-31g* Energy Surfaces for Disaccharide Analogs Despite the inability of analogs to make hydrogen bonds, their energy surfaces account fairly well for the conformations that are observed in crystals of the disaccharides. Thus, torsional energy and the simple bulk of ring structures are major factors in determining the disaccharide conformations. The shapes around the global minima depended on the number of anomeric carbons involved in the linkage, and the propensity for possibly important secondary minima with relative energies of 2 to 4 kcal/mol depended on whether the bond was axial or equatorial. www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=109783&pf=1   (420 words)

GlycoForum / Science of Hyaluronan-1 Both sugars are spatially related to glucose which in the beta configuration allows all of its bulky groups (the hydroxyls, the carboxylate moiety and the anomeric carbon on the adjacent sugar) to be in sterically favorable equatorial positions while all of the small hydrogen atoms occupy the less sterically favorable axial positions. The average length of a disaccharide is ~1 nm. In a physiological solution, the backbone of a hyaluronan molecule is stiffened by a combination of the chemical structure of the disaccharide, internal hydrogen bonds, and interactions with solvent. www.glycoforum.gr.jp /science/hyaluronan/HA01/HA01E.html   (2262 words)

Home The disaccharide units may be biosynthetically modified as N-acetyl or N-sulfate glucosamine, 2-O-sulfate uronic acid and 6-O-sulfate and/or 3-O-sulfate glucosamine. The disaccharide units in the derivative are either glucose -> glucosamine or idose -> glucosamine. The altered disaccharide residues in the derivative become uronic acid -> glucosamine, while the unmodified disaccharide units remain as uronic acid -> N - acetyl-glucosamine. www.heparinoids.com /catalog.htm   (925 words)

Disaccharides and Oligiosaccharides This section is divided into the reducing and non-reducing types of disaccharide. If two monosaccharides are linked through their anomeric centers the disaccharide formed is a non-reducing disaccharide. Sucrose (β-D-fructofuranosyl α-D-glucopyranoside) is the predominant disaccharide found in sugar cane and sugar beet. faculty.virginia.edu /mcgarveylab/Carbsyn/Carblist/html/disacch.html   (1024 words)

[No title] In the process of disaccharide formation, a molecule of water is lost and the reaction is termed dehydration synthesis. An example of this type of reaction, in which the disaccharide maltose is formed from two glucose molecules, may be represented as follows: The chemical combination of two glucose molecules (monosaccharides) produces the disaccharide maltose, or malt sugar. Note that the molecular formula for disaccharides, as represented by maltose, is. academic.wsc.edu /mathsci/bauer_j/writing.doc   (581 words)

Keratan sulfate disaccharide composition determined by FACE analysis of keratanase II and endo-{beta}-galactosidase ... Hounsell, E., Feeney, J., Scudder, P., Tang, P., and Feizi, T. (1986) 1H-NMR studies at 500 MHz of a neutral disaccharide and sulphated di-, tetra-, hexa- and larger oligosaccharides obtained by endo-beta-galactosidase treatment of keratan sulphate. Ota, M., Takamura, N., and Irimura, T. (2000) Involvement of cell surface glycans in adhesion of human colon carcinoma cells to liver tissue in a frozen section assay: role of endo-beta-galactosidase-sensitive structures. Plaas, A.H.K., West, L.A., Midura, R.J. and Hascall, V.C. (2001) Disaccharide composition of hyaluronan and chondroitin/dermatan sulfate. glycob.oxfordjournals.org /cgi/content/full/11/10/779   (6204 words)

Nonreducing End Structures of Chondroitin Sulfate Chains on Aggrecan Isolated from Swarm Rat Chondrosarcoma Cultures -- ... In addition, mercuric acetate treatment was employed to convert the unsaturated disaccharides to their respective substituted GalNAc derivatives by degrading the unsaturated uronosyl residue and cleaving the glycosidic bond(20, 21, 22), while leaving the saturated disaccharides intact. H ratio of 2.3 for the disaccharide peak 2 in Fig. A novel observation was made concerning the internal disaccharide composition of the CS chains from rat chondrosarcoma aggrecan. www.jbc.org /cgi/content/full/270/14/8009   (5845 words)

Carbohydrates - Chemical Structure, Simple Carbohydrates, Complex Carbohydrates, Digestion and Absorption, Glycolysis Instead, it often combines with glucose to form the disaccharide lactose, often referred to as milk sugar. Those composed of two sugars are specifically referred to as disaccharides, or double sugars. Pancreatic amylase breaks starch into disaccharides and small polysaccharides, and enzymes from the cells of the small-intestinal wall break any remaining disaccharides into their monosaccharide components. www.faqs.org /nutrition/Ca-De/Carbohydrates.html   (2481 words)

A Disaccharide Precursor of Sialyl Lewis X Inhibits Metastatic Potential of Tumor Cells -- Fuster et al. 63 (11): 2775 ... A Disaccharide Precursor of Sialyl Lewis X Inhibits Metastatic Potential of Tumor Cells -- Fuster et al. on the disaccharides diverts the assembly of sLe The extent of adhesion was normalized to the value obtained for cells not treated with disaccharide. cancerres.aacrjournals.org /cgi/content/full/63/11/2775   (4820 words)

HF/6-31G* Energy Surfaces for Disaccharide Analogs   (Site not responding. Last check: 2007-10-17) Quantum mechanical HF/6-31G* theory was used to calculate Ramachandran energy surfaces for 12 analogs of disaccharides. Despite the absence of hydroxyl groups, the surfaces account well for the conformations that are observed in crystals of the related disaccharides. The contour shapes around the global minima depend on the number of anomeric carbons involved in the linkage, while the propensity for alternative minima that have relative energies less than 4 kcal/mol depends mostly on whether the linkage bond in question is axial or equatorial. pollux.chem.umn.edu /publications/abstract143.html   (238 words)

Anomalous Structure of Urinary Glycosaminoglycans in Patients with Pseudoxanthoma Elasticum -- Maccari et al. 49 (3): ... HPLC chromatograms of unsaturated disaccharide calibrators (A), unsaturated disaccharides from CS extracted and purified from normal urine (B), and unsaturated disaccharides from CS extracted and purified from PXE-affected urine (C). HPLC separation of unsaturated nonsulfated and variously sulfated disaccharides of HS after treatment with heparinase and heparitinase I. HPLC chromatograms of unsaturated disaccharides from HS extracted and purified from normal (A) and PXE-affected (B) urine. Volpi N. Hyaluronic acid and chondroitin sulfate unsaturated disaccharides analysis by high-performance liquid chromatography and fluorimetric detection with dansylhydrazine. www.clinchem.org /cgi/content/full/49/3/380   (4461 words)

Tertiary Structure of Staphylococcus aureus Cell Wall Murein -- Dmitriev et al. 186 (21): 7141 -- The Journal of ...   (Site not responding. Last check: 2007-10-17) It is noteworthy that the simulation orients the arms of the peptide antenna perpendicularly to the axis of the disaccharide moiety. Twin barrels correspond to the disaccharide units; those marked with a darker color (1 and 1') are above those marked with a lighter color (2 and 2'). The semicircular arrow points to the ends of short and long peptide arms which belong to two bridges that need to be connected. jb.asm.org /cgi/content/full/186/21/7141   (5573 words)

Maunula: Towards the Synthesis of the Disaccharide Fragment of Pradimicin, ISBN 951-22-7038-2 Dissertation for the degree of Doctor of Philosophy to be presented with due permission of the Department of Chemical Technology for public examination and debate in Auditorium KE 2 (Komppa Auditorium) at Helsinki University of Technology (Espoo, Finland) on the 18 Pradimicin is a novel antibiotic consisting of a benzo[a]naphthacenequinone aglycon, an amino acid and a disaccharide fragment. In this study, the α-analogue of the disaccharide derivative of pradimicin A was synthesized in its protected form. lib.tkk.fi /Diss/2004/isbn9512270382   (283 words)

Enzymatic Synthesis in Vitro of the Disulfated Disaccharide Unit of Corneal Keratan Sulfate -- Akama et al. 277 (45): ... Enzymatic Synthesis in Vitro of the Disulfated Disaccharide Unit of Corneal Keratan Sulfate -- Akama et al. disaccharide units of keratan sulfate GAG are monosulfated disaccharide The remaining structure is further sulfated on the Gal residues by KSG6ST to produce highly sulfated keratan sulfate disaccharides. www.jbc.org /cgi/content/full/277/45/42505   (5383 words)

Abstract: Detection of a potential receptor for the H blood group antigen on rat colon carcinoma cells and normal ... Up-regulation of the synthesis of carbohydrate tumor-associated antigens terminated by the disaccharide Fucα1-2Gal is frequent in colon carcinoma and associated with poor prognosis. Using polyacrylamide-based neoglycoconjugates, we looked for a potential receptor for this disaccharide, and observed that a neoglycoconjugate probe containing the H-disaccharide could bind rat colon-carcinoma cells in a dose-dependent manner, whereas very little binding was evidenced when a probe containing glucose was used. Binding of the H-disaccharide probe could be inhibited by the free H-disaccharide as well as by unlabeled neoglycoconjugates containing a terminal H-disaccharide. carbohyd.siobc.ras.ru /abstract.php?id=58   (299 words)

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