
	Where results make sense

Topic: Disseminated intravascular coagulation

Related Topics

Microangiopathic hemolytic anemia

Thrombotic thrombocytopenic purpura

Immune thrombocytopenic purpura

Prothrombin time

Hemolytic uremic syndrome

Thrombocytopenia

Paroxysmal nocturnal hemoglobinuria

HELLP syndrome

Sheehan syndrome

Antiphospholipid syndrome

Hyperprolactinemia

Adrenal gland

Warfarin

Folic acid

Pituitary adenoma

	Disseminated intravascular coagulation - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-10-13)
		Disseminated intravascular coagulation (DIC) is a pathological process in the body where the blood starts to coagulate throughout the whole body.
		DIC results in lower fibrinogen (as it has all been converted to fibrin), and this can be tested for in the hospital lab.
		The prognosis for those with DIC, depending on its cause, is often grim, leading the acronym to be known colloquially as "death is coming" [1].
	www.sciencedaily.com /encyclopedia/disseminated_intravascular_coagulation (466 words)

	MedlinePlus Medical Encyclopedia: Disseminated intravascular coagulation (DIC)
		DIC is a disorder of the "clotting cascade." It results in depletion of clotting factors in the blood.
		DIC is when your body's blood clotting mechanisms are activated throughout the body instead of being localized to an area of injury.
		Risk factors are recent sepsis, recent injury or trauma, recent surgery or anesthesia, complications of labor and delivery, leukemia or disseminated cancer, recent blood transfusion reaction, and severe liver disease.
	www.nlm.nih.gov /medlineplus/ency/article/000573.htm (443 words)

	DIC (disseminated intravascular coagulation) (Site not responding. Last check: 2007-10-13)
		DIC is a disorder of diffuse activation of the clotting cascade that results in depletion of clotting factors in the blood.
		Disseminated intravascular coagulation (DIC) occurs when the blood clotting mechanisms are activated throughout the body instead of being localized to an area of injury.
		DIC may be stimulated by many factors including infection in the blood by bacteria or fungus, severe tissue injury as in burns and head injury, cancer, reactions to blood transfusions, and obstetrical complications such as retained placenta after delivery.
	www.shands.org /health/information/article/000573.htm (378 words)

	Disseminated Intravascular Coagulation (Site not responding. Last check: 2007-10-13)
		Disseminated intravascular coagulation (DIC) is a phenomenon characterized by activation of procoagulants.
		DIC is not a disease; it is a phenomenon that results from many different diseases, such as infections, malignant diseases, trauma, and some obstetric problems.
		Coagulation factors and platelets are consumed in this generalized clotting process, resulting in deficiency of coagulation proteins and thrombocytopenia, which increases the tendency to bleeding.
	www.lakeside.ca /Patient_Info/dic.htm (646 words)

	Directory of open access journals
		Disseminated intravascular coagulation arises from an overwhelming of the haemostatic regulatory mechanisms leading to an excessive generation of thrombin and a failure of the normal inhibitory pathways to prevent systemic effects of this enzyme.
		Patient was begun on high dose intravenous steroids with improvement of the disseminated intravascular coagulation laboratory values within 12 hours and resolution of disseminated intravascular coagulopathy within 4 days.
		Although disseminated intravascular coagulation associated with ulcerative colitis is usually related to septicemia, toxic megacolon or surgery, we present a case of an ulcerative colitis flare resulting in disseminated intravascular coagulation and a bladder hematoma.
	www.doaj.org /abstract?id=102847&year=2004&volume=4&issue=1&toc=y (272 words)

	DIC Disseminmated Intravascular Coagulation.
		DIC once referred to secondary activation of the coagulation system with fibrin deposition in the microvascularture.
		DIC is a major cause of acute renal failure and it also contributes to multiple system organ failure.
		Cornerstone treatment of DIC is the alleviation of the primary disorder.
	rnbob.tripod.com /dic.htm (392 words)

	Disseminated intravascular coagulation (Site not responding. Last check: 2007-10-13)
		This depletes the body of its platelets and coagulation factors, and there is an increased the risk of haemorrhage.
		There are a variety of causes of DIC, all usually causing the release of chemicals into the blood that instigates thecoagulation.
		DIC results in lower fibrinogen (as it has all been converted to fibrin),and this can be tested for in the hospital lab.
	www.therfcc.org /disseminated-intravascular-coagulation-111607.html (228 words)

	Disseminated Intravascular Coagulation - WSAVA 2002
		DIC, previously called consumptive coagulopathy or defibrination syndrome, is a complex syndrome in which excessive intravascular coagulation leads to multiple-organ microthrombosis (multiple organ failure-MOF) and paradoxical bleeding caused by the inactivation or excessive consumption of platelets and clotting factors secondary to enhanced fibrinolysis.
		DIC is not a specific disorder but rather a common pathway in a variety of disorders.
		Several hematologic findings help support a presumptive clinical diagnosis of DIC and include a regenerative hemolytic anemia (although occasionally, because the animal has a chronic disorder such as cancer, the anemia is nonregenerative), hemoglobinemia (caused by intravascular hemolysis), RBC fragments or schistocytes, thrombocytopenia, neutrophilia with a left-shift, and rarely neutropenia.
	www.vin.com /proceedings/Proceedings.plx?CID=WSAVA2002&PID=2596 (1441 words)

	eMedicine - Disseminated Intravascular Coagulation : Article by Alvin H Schmaier, MD
		Background: Disseminated intravascular coagulation (DIC) is a clinicopathologic syndrome of activated coagulation that manifests with bleeding or thrombosis.
		Biochemically, DIC is characterized by evidence of the simultaneous presence of thrombin and plasmin.
		Chronic or subacute DIC: In patients with so-called chronic or subacute DIC whose manifestation is thrombosis from excess thrombin formation, the symptoms and signs of venous thrombosis may be present.
	www.emedicine.com /med/topic577.htm (2324 words)

	Disseminated Intravascular Coagulation (DIC) Profile, Comprehensive Plus
		DIC can develop secondary to conditions including: obstetric accidents (placental abruption, sptic abortion), intravascular hemolysis (transfusion reactions), septicemia, viremia, metastatic malignancy, leukemia, burns, severe trauma, acute liver disease, prosthetic devices and vascular disorders.
		DIC occurs when the normal hemoststic balance is disrupted as the ressult of a systemic activation of the procoagulant and fibrinolytic systems.
		Over-activation of the coagulation cascade can, in turn, result in bleeding due to the depletion of platelets, fibrinogen, prothrombin and other hemostatic proteins in what is referred to as a consumption coagulopaty.
	www.labcorp.com /datasets/labcorp/html/chapter/mono/cf004500.htm (906 words)

	MEDSTUDENTS-INTENSIVE CARE
		Chronic DIC is usually associated with carcinomatosis, retained dead fetus syndrome or an aneurysm or hemangioma.
		Carcinoma may cause DIC by invasion of tissues and release of tissue factor, activation of leucocytes, secretion of tissue factor and direct activation of the prothrombinase complex.
		Also, as therapy for sepsis is improved, less cases of DIC are expected, so that we have good reasons to be optimistic and continue research on this topic, which is one of the most challenging issues in the Intensive Care field.
	www.medstudents.com.br /terin/terin2.htm (1949 words)

	CHEST: Disseminated intravascular coagulation in sepsis (Site not responding. Last check: 2007-10-13)
		Disseminated intravascular coagulation is a frequent complication of sepsis.
		Coagulation activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a procoagulant state resulting in inadequate fibrin removal and fibrin deposition in the microvasculature.
		Then, the pathophysiology of coagulation activation, consumption of coagulation inhibitors, and the inhibition of fibrinolysis leading to a procoagulant state are described in more detail.
	www.findarticles.com /p/articles/mi_m0984/is_4_128/ai_n15795175 (182 words)

	Disseminated Intravascular Coagulation: Bleeding and Clotting Disorders: Merck Manual Home Edition (Site not responding. Last check: 2007-10-13)
		Disseminated intravascular coagulation is a condition in which small blood clots develop throughout the bloodstream, blocking small blood vessels and depleting the platelets and clotting factors needed to control bleeding.
		The excessive clotting is usually stimulated by a substance that enters the blood as part of a disease (such as an infection or certain cancers) or as a complication of childbirth, retention of a dead fetus, or surgery.
		DIC that develops suddenly is life threatening and is treated as an emergency.
	www.merck.com /mmhe/sec14/ch173/ch173h.html (334 words)

	Disseminated Intravascular Coagulation
		DIC is a thrombohemorrhagic disorder characterized by primary thrombotic and secondary hemorrhagic diathesis causing multi-organ failure.
		DIC is not a primary disease. It is a complication of a variety of diseases which cause pathologic activation of the extrinsic and/or intrinsic coagulation pathways.
		Finally, DIC is characterized by concurrent thrombocytopenia and depletion of coagulation factors and antiboagulants such as antithrombin III, protein C and protein S. The formation of fibrin within the microcirculation causes microangiopathic hemolytic anemia with schistozyte and keratocyte formation due to damaged membranes of erythrocytes.
	www.addl.purdue.edu /newsletters/2005/Winter/DIC.htm (156 words)

	eMedicine - Disseminated Intravascular Coagulation : Article Excerpt by: Mary A Furlong, MD (Site not responding. Last check: 2007-10-13)
		Background: Disseminated intravascular coagulation (DIC) is a complex systemic thrombohemorrhagic disorder involving the generation of intravascular fibrin and the consumption of procoagulants and platelets.
		DIC is a pathophysiologic term describing a continuum of events that occur in the coagulation pathway in association with a variety of disease states.
		Pathophysiology: The pathophysiology of DIC involves the initiation of coagulation via endothelial injury or tissue injury and the subsequent release of procoagulant material in the form of cytokines and tissue factors.
	www.emedicine.com /emerg/byname/disseminated-intravascular-coagulation.htm (668 words)

	Disseminated intravascular coagulation (Site not responding. Last check: 2007-10-13)
		This depletes body of its platelets and coagulation factors and there is increased the risk of haemorrhage.
		There are a variety of causes of all usually causing the release of chemicals the blood that instigates the coagulation.
		are not given as by now all coagulation factors and platelets have been used These must be replaced by platelet transfusion and fresh frozen plasma to restore levels.
	www.freeglossary.com /Disseminated_intravascular_coagulation (434 words)

	Disseminated Intravascular Coagulation (Site not responding. Last check: 2007-10-13)
		LEO Pharma has also begun development of ATryn(r) in Europe as a potential treatment for disseminated intravascular coagulation, or DIC, associated with severe...
		The fibrin deposition in coagulation can block blood vessels, leading to ischaemic damage to some tissues.
		As well as this, red blood cells are damaged as they get shredded by the fibrin.
	www.wikiverse.org /disseminated-intravascular-coagulation (292 words)

	eMedicine - Disseminated Intravascular Coagulation : Article by Alvin H Schmaier, MD
		DIC is not a specific diagnosis, and its presence always indicates another underlying disease.
		Acute DIC: The physical findings associated with DIC usually are those of the underlying or inciting etiology; however, patients with acute DIC (ie, hemorrhagic variety associated with excess plasmin formation) have petechiae on the soft palate and legs from thrombocytopenia and ecchymosis at the venipuncture sites.
		Alternatively, DIC can appear as an indolent, subacute, or chronic disorder that is not associated with bleeding and presents as thrombosis as result of excess thrombin formation.
	www.emedicine.com /MED/topic577.htm (2324 words)

	Disseminated intravascular coagulation - Patient UK
		Disseminated intravascular coagulation - Patient UK PatientPlus articles are written for doctors and so the language can be technical.
		DIC is characterized by evidence of both thrombin and plasmin.
		In acute disseminated intravascular coagulation PT and aPTT are prolonged, and the platelet count and fibrinogen decrease.
	www.patient.co.uk /showdoc/40001040 (936 words)

	Agen Biomedical D-dimer Reference Centre (Site not responding. Last check: 2007-10-13)
		Such is the case in Disseminated Intravascular Coagulation (DIC), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), coronory heart disease and other arterial and venous thrombotic states.
		Although the hemorrhagic aspect of this disorder is not an insurmountable clinical consideration, it is the small and large vessel thromboses as a consequence of excess thrombin activation and fibrin deposition leading to reduced vascular flow, ischemia, and associated end-organ damage, that usually lead to irreversible morbidity and mortality.
		Although DIC has been described as low grade compensated or fulminant, commonly when a patient presents with suspected DIC such a clear differentiation of the disease process is unclear.
	www.agen.com.au /d-dimer/clinapp.htm (353 words)

	Disseminated Intravascular Coagulation (Site not responding. Last check: 2007-10-13)
		DIC is the syndrome that occurs when the clotting cascade goes awry.
		In DIC, the quantity of plasmin is significantly increased, leading to the generation of significant quantities of fibrin degradation products.
		DIC usually occurs because of an underlying cause.
	medinfo.ufl.edu /year2/coag/dic.html (379 words)

	Postgraduate Medicine: Disseminated intravascular coagulation
		DIC occurs when monocytes and endothelial cells are activated or injured by toxic substances elaborated in the course of certain diseases.
		Acute DIC: Acute promyelocytic leukemia, acute myelomonocytic or monocytic leukemia, disseminated prostatic carcinoma
		Disseminated intravascular coagulation in patients with multiple organ failure of non-septic origin.
	www.postgradmed.com /issues/2002/03_02/messmore.htm (1462 words)

	March, 1999 - Disseminated Intravascular Coagulation
		DIC is an acquired coagulation disorder with uncontrolled intravascular activation of coagulation and secondary fibrinolysis.
		Hence, the absence of thrombocytopenia excludes the diagnosis of DIC.
		Disseminated intravascular coagulation: objective clinical and laboratory diagnosis, treatment, and assessment of therapeutic response.
	www.itxm.org /TMU1998/tmu3-99.htm (1060 words)

	Disseminated Intravascular Coagulopathy (DIC) - FROM RONNIE Falcão's MIDWIFE ARCHIVES
		DIC is a situation of inappropriate coagulation within the blood vessels which leads to the consumption of clotting factors, thus resulting in the failure of the clotting mechanism at the site of bleeding.
		DIC begins with an event (possibly one of the above) that triggers widespread clotting with the formation of microthrombi throughout the circulation.
		So, DIC is not just a pregnancy related condition (DIC can occur in non-pregnant men, women and children), but it can become even worse due to the placental site being an open bleeding wound, and that the FDPs are interfering with the normal ligation of the vessels in the site.
	www.gentlebirth.org /archives/dic.html (772 words)

	Kongressberichte: A case of disseminated intravascular coagulation after intravenous injection of methadone capsules (Site not responding. Last check: 2007-10-13)
		Kaolin is a potent inducer of the intrinsic pathway of coagulation and is widely used in laboratory settings.
		We hypothesize that this patient developed disseminated intravascular coagulation (DIC) after intravenous administration of methadone capsules containing kaolin.
		As no other coagulation factors than fibrinogen were measured quantitatively, a pure hyperfibrinolysis cannot formally be excluded.
	www.toxi.ch /ger/congres_1083577175_24254.html (402 words)

	eMedicine - Disseminated Intravascular Coagulation : Article by Mary A Furlong, MD (Site not responding. Last check: 2007-10-13)
		Chronic DIC is characterized by subacute bleeding and diffuse thrombosis.
		DIC may be the result of a single or multiple conditions.
		Bick RL: Syndromes of disseminated intravascular coagulation in obstetrics, pregnancy, and gynecology.
	www.emedicine.com /emerg/topic150.htm (3348 words)

Try your search on: Qwika (all wikis)