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Topic: Distal convoluted tubule

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Macula densa

Osmotic pressure

Parathyroid hormone

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Confocal laser scanning microscopy

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	Distal convoluted tubule - Wikipedia, the free encyclopedia
		The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting duct system.
		and absorbing Na Sodium absorption by the distal tubule is mediated by the hormone aldosterone.
		Thiazide diuretics inhibit Na /Cl reabsorption from the DCT.
	en.wikipedia.org /wiki/Distal_convoluted_tubule (223 words)

	Magnesium Transport in the Renal Distal Convoluted Tubule -- Dai et al. 81 (1): 51 -- Physiological Reviews
		are absorbed in the distal tubule (19, 92, 93, 248, 252,
		that magnesium is reabsorbed in the superficial distal tubule,
		tubule, loop of Henle, and distal tubule (83, 113).
	physrev.physiology.org /cgi/content/full/81/1/51 (7807 words)

	[No title]
		In the proximal convoluted tubule all the glucose and amino acids are recovered by active transport across the tubular epithelium.
		In the distal convoluted tubule the movement of sodium, potassium and hydrogen ions are actively transported by a carrier mediated mechanism under the control of aldosterone.
		The cells of the distal convoluted tubule and afferent arteriole of a nephron are in close contact and are modified to a structure called the macula densa.
	www.nvo.com /jin/homepage4 (3188 words)

	The Urinary System
		The squamous parietal epithelium is continuous with the proximal convoluted tubule at the urinary pole (the point at which the proximal convoluted tubule joins the renal corpuscle).
		The macula densa is a region of the distal tubule adjacent to the vascular pole of the renal corpuscle.
		The distal tubule and the ascending thick limb (in the medullary ray) have a more cuboidal epithelium and, unlike, slide 74 odd, there is some staining of their cell borders.
	ect.downstate.edu /courseware/histomanual/urinary.html (1619 words)

	General Biology 2, lecture on Homeostasis
		In the thick region of the ascending limb Na is actively pumped from the tubule to the tissue fluid in the upper medulla.
		The osmotic potential of the filtrate decreases as the filtrate in the ascending limb moves from the inner medulla to the distal convoluted tubule.
		Approximately 65 -75% of the water and salts in the filtrate are reabsorbed from the proximal convoluted tubule.
	www.usd.edu /biol/genbio/153/ken/kr10.html (2280 words)

	Laboratory Twenty: Urinary System
		Cells of the macula densa are located in the wall of distal convoluted tubule adjacent to the vascular pole.
		Distal convoluted tubules have cuboidal epithelial cells that lack brush borders and have their nuclei situated near its apical surface.
		Compare the distribution of the tubules as one proceeds from the base of the pyramid (near the cortex of the kidney) to the apex of the pyramid (projects toward the calyx).
	medinfo.ufl.edu /year1/histo/review/lab20.html (1531 words)

	Untitled
		distal convoluted tubule and the efferent arteriole b.
		proximal convoluted tubule and the efferent arteriole e.
		OR B. Contrast the roles of aldosterone and ADH in the regulation of osmolarity balance by the renal tubules.
	www2.sunysuffolk.edu /kisield/23042293.htm (937 words)

	SIU SOM Histology CRR
		The length of a proximal convoluted tubule tends to be several times greater than that of a distal convoluted tubule, so sections of proximal tubules are much more common than those of distal tubules in a typical histological slide of renal cortex.
		The epithelium of the initial descending segment of the loop of Henle is similar to that of the proximal convoluted tubule, and is sometimes called the pars recta of the proximal tubule (in contrast to the convoluted pars convoluta).
		The macula densa is a patch of densely-packed epithelial cell nuclei along the distal convoluted tubule, adjacent to the afferent arteriole at the vascular pole of the corpuscle from which the tubule arose.
	www.siumed.edu /~dking2/crr/rnguide.htm (4384 words)

	[No title] (Site not responding. Last check: 2007-10-17)
		A distal convoluted tubule has been cut longitudinally and is located on the left of this slide.
		A macula densa of the distal convoluted tubule is at the left.
		The solitary dark-staining tubule at the left represents a straight portion of the proximal convoluted tubule.
	www.georgetown.edu /dml/educ/micro/urin/urin.txt (1192 words)

	[No title]
		As the reduced volume of filtrate ascends toward the distal convoluted tubule in the cortex, the removal of chloride and sodium (but not water) by the cells lining this portion of the loop causes the fluid in its lumen to gradually become isotonic or hypotonic.
		The distal tubule cpithelium forms a disk of tightly packed columnar cells called a macula densa at the point near the vascular pole of a renal corpuscle where it contacts an afferent arteriole.
		While the distal tubules are impermeable to water, the increased tonicity of blood leaving the kidneys draws water into the blood as it passes through other tissues, increasing blood volume and pressure.
	www.loyno.edu /~chood/histnoteuro.html (3463 words)

	Mammalian Distal Tubule: Physiology, Pathophysiology, and Molecular Anatomy -- Reilly and Ellison 80 (1): 277 -- ...
		to the distal tubule of the micropuncture literature and comprises
		from TAL to DCT and at the junction with the CNT.
		of the distal tubule comprises primarily DCT, CNT, and intercalated
	physrev.physiology.org /cgi/content/full/80/1/277 (8741 words)

	NDI Terminology - tubule (Site not responding. Last check: 2007-10-17)
		distal convoluted tubule - A distal, rolled-together or coiled part of the ascending limb of the renal tubule (see below), extending from the distal straight tubule (see below) to the junctional (connecting) tubule (see below).
		distal straight tubule - Part of the renal tubule (see below) primarily on the ascending limb, extending from the thin tubule (see below) to the distal convoluted tubule (see above).
		renal tubule - One of the minute, reabsorptive, secretory, and collecting canals, made up of basement membrane lined with epithelium, that form the substance of the kidneys.
	www.ndif.org /Terms/tubule.html (309 words)

	Histology-World! Histology Test Bank-Renal 2a
		The proximal convoluted tubule leads to the loop of Henle.
		The distal convoluted tubule then leads to the collecting duct.
		The macula densa are specialized cells in the distal convoluted tubule that are sensitive to sodium.
	www.histology-world.com /testbank/renal2a.htm (730 words)

	Kidneys: Biology of the Kidneys and Urinary Tract: Merck Manual Home Edition
		Each tubule has three interconnected parts: the proximal convoluted tubule, the loop of Henle, and the distal convoluted tubule.
		All of the glomeruli are located in the cortex, while the tubules reside in both the cortex and the medulla.
		In the first part of the tubule, most of the sodium, water, glucose, and other filtered substances are reabsorbed and ultimately returned to the blood.
	www.merck.com /mmhe/sec11/ch141/ch141b.html (803 words)

	Cloning and localization of KCC4 in rabbit kidney: expression in distal convoluted tubule -- Velázquez and Silva ...
		Unidirectional potassium fluxes in renal distal tubule: effects of chloride and barium.
		Thiazide-sensitive sodium chloride cotransport in the early distal tubule.
		In situ studies of distal convoluted tubule in rat.
	ajprenal.physiology.org /cgi/content/full/285/1/F49 (5721 words)

	Distribution of Cell Membrane-associated Proteins Along the Human Nephron -- Kwon et al. 46 (12): 1423 -- Journal of ...
		In the same section, the intensity of staining is weak in cells of the descending thin limb of Henle, stronger in distal straight tubules, and strongest in distal convoluted tubules and collecting ducts.
		Distal straight tubule, distal convoluted tubule, and collecting duct show strong, widely spaced punctate staining along the luminal surface, consistent with the flattened morphology of the cells.
		The intensity of the staining is weakest in cells of proximal straight tubule and collecting duct, although it becomes stronger on the basolateral membrane of collecting duct cells in inner stripes of the outer medulla.
	www.jhc.org /cgi/content/full/46/12/1423 (5043 words)

	URINARY SYSTEM
		The pale areas radiating from the medulla into the cortex are medullary rays, which contain the straight collecting tubules and straight portions of proximal and distal tubules.
		most of the proximal convoluted tubules are collapsed and they appear to have a pink lumen.
		The tubules with tall cuboidal cells that have distinct lateral borders (negatively stained in this prep) are the collecting tubules.
	medocs.ucdavis.edu /CHA/402/labsyl/01/09.htm (1059 words)

	VI. Mechanisms of Salt & Water Reabsorption
		The distal tubule receives an hypotonic fluid, reabsorbs additional NaCl from it and, in the presence of ADH, reabsorbs sufficient water to bring the fluid to isotonicity.
		Mechanisms of NaCl reabsorption in the distal convoluted tubule.
		The collecting tubule has the ability to vary the urine composition over very wide ranges and this can result in large changes in the composition of the plasma and extracellular fluid.
	www2.kumc.edu /ki/physiology/course/six/6_3.htm (873 words)

	A Chloride Channel at the Basolateral Membrane of the Distal-convoluted Tubule: a Candidate ClC-K Channel -- Lourdel et ...
		The distal-convoluted tubule (DCT) of the kidney absorbs NaCl
		The cortical thick ascending limb and early distal convoluted tubule in the urinary concentrating mechanism.
		Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy.
	www.jgp.org /cgi/content/full/121/4/287 (6800 words)

	Kidney
		Glomerulus, proximal convoluted tubule, loop of Henle, distal convoluted tubule and collecting ducts.
		Vasopressin and angiotensin II release: net effect to increase salt absorption in the proximal tubule and loop of Henle.
		Absorbed in proximal tubule and in the loop of henle.
	www.meddean.luc.edu /lumen/meded/mech/cases/case24/kidney.htm (396 words)

	Estradiol Enhances Thiazide-sensitive NaCl Cotransporter Density in the Apical Plasma Membrane of the Distal Convoluted ...
		The distal convoluted tubule is a homogeneous segment composed of tall, cuboidal epithelial cells that contain extensive basolateral plasma membrane infoldings, long, vertically oriented mitochondria that are regularly spaced between the basolateral plasma membrane infoldings, an apically situated nucleus, moderate apical plasma membrane microprojections, and few apical cytoplasmic vesicles.
		The boundary length of the apical plasma membrane within a fixed span of the apical surface of DCT cells was significantly increased in OVX-EST rats compared with OVX-VEH rats, indicating that the number or length of apical plasma membrane microprojections in DCT cells was significantly increased by estradiol replacement.
		cotransporter in the apical plasma membrane of the distal convoluted
	www.jci.org /cgi/content/full/101/8/1661 (5155 words)

	Renal System Anatomy Including Kidneys - nephrologychannel
		Urine formation occurs in the renal tubules, which travel from the outer tissue of the kidney (called the cortex), to the inner tissue (called the medulla), and return to the cortex.
		Substances that remain in the urine are reabsorbed, increasing the concentration of the urine.
		Antidiuretic hormone, aldosterone, and atrial natriuretic factor are hormones that change the permeability of the distal convoluted tubule and the collecting tubule, regulating urine volume and helping to maintain blood pressure.
	www.nephrologychannel.com /anatomy.shtml (697 words)

	[No title] (Site not responding. Last check: 2007-10-17)
		(b) Reabsorption occurs in the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, and the collecting duct.
		From Bowman’s capsule, the filtrates pass sequentially through the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, the collecting duct, the ureter, and finally to the urinary bladder.
		When blood volume decreases, the concentration of salts increases; this change is sensed by the hypothalamus, which in turn stimulates the posterior lobe of the pituitary to release ADH.
	www.cord.edu /faculty/jrutherf/homeworkkey-ch46.doc (371 words)

	Alwanza: Healthcare: Urinary System Tutorial
		The purpose of the renal corpuscle is to extract the renal filtrate (it is not yet to be called urine) from blood.
		Peritubular Capillaries: The network of capillaries surrounding the proximal convoluted tubule, the loop of Henle and the distal convoluted tubule.
		absorption of some plasma and nutrients from the renal filtrate by the peritubular capillaries from the proximal and distal convoluted tubules and the loop of Henle (aka tubular reabsorption).
	www.alwanza.com /healthcare/urinaryInfo.html (1123 words)

	CRR HISTOLOGY SAQ urinary tract
		A principal function for the distal convoluted tubule is:
		closely-packed nuclei in the epithelium of the proximal convoluted tubule.
		epithelial cells of proximal and distal convoluted tubules.
	www.siumed.edu /~dking2/crr/SAQrn.htm (1554 words)

	Negative regulators of sodium transport in the kidney: Key factors in understanding salt-sensitive hypertension? -- ...
		The components comprising the aldosterone-sensitive distal nephron are shown in bright yellow.
		The aldosterone-sensitive distal nephron expresses genes needed for the specificity of the aldosterone signaling cascade, i.e.
		Loffing, J., and Kaissling, B. Sodium and calcium pathways along the mammalian distal nephron: from rabbit to human.
	www.jci.org /cgi/content/full/111/7/947 (2114 words)

	Vasopressin-stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted ...
		of the renal tubule and is regulated by hormones [1,2].
		Morphology of immortalized late DCT, CCD and IMCD cells.Confluent mpkDCT (A), mpkCCD (B) and mpkIMCD (C) cells have a uniform shape and form domes.
		the distal tubule that is similar in the mouse, rat and rabbit.
	ndt.oxfordjournals.org /cgi/content/full/16/2/238 (3384 words)

	Mutations in the Chloride Channel Gene, CLCNKB, Leading to a Mixed Bartter-Gitelman Phenotype -- JECK et al. 48 (6): ... (Site not responding. Last check: 2007-10-17)
		by impaired NaCl reabsorption in the distal convoluted tubule
		in the distal thiazide-sensitive sodium chloride transport (9).
		Sutton RA, Marichak V, Halebe A, Wilkins GE 1992 Bartter’s syndrome: evidence suggesting a distal tubular defect in a hypocalciuric variant of the syndrome.
	www.pedresearch.org /cgi/content/full/48/6/754 (3267 words)

	[No title]
		Proximal convoluted tubule Glomerulus and Bowman's capsule Loop of Henle Proximal part of the distal convoluted tubule Distal part of the distal convoluted tubule Collecting tubule
		Kidney tubule is the target tissue of ______.
		The portion of the nephron that lies within the medulla is: Proximal convoluted tubule Distal tubule Bowman's capsule Loop of Henle
	www2.eou.edu /~dkerley/hphys/FINAL.HTM (4399 words)

	urinary (Site not responding. Last check: 2007-10-17)
		increasing the synthesis and insertion into membrane of water channel proteins in the cells of the collecting duct of the renal tubule.
		decreasing the synthesis and insertion into membrane of water channel proteins in the cells of the collecting duct of the renal tubule.
		Having the ascending and descending tubules and the collecting duct adjacent to one another and having the Loop surrounded by the vasa recta helps create the concentration gradients and osmotic forces which drive the process.
	www.utm.edu /staff/amills/urinary.htm (1274 words)

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