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docosanol topical Docosanol is an antiviral medication used to treat cold sore infections caused by the herpes simplex virus. Docosanol topical is used to treat cold sores on the face and lips. Docosanol topical should be applied at the very first sign of a cold sore, such as the tingle, redness, bump, or itch. hw.healthdialog.com /kbase/multum/d04702a1.htm   (1138 words)

MedicineOnline.com Drug Information: Docosanol (Topical)   (Site not responding. Last check: 2007-10-15) Although topical docosanol will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. Children—Although there is no specific information comparing use of docosanol in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. Docosanol is best used as soon as possible after the signs and symptoms of herpes infection (for example, pain, burning, or blisters) begin to appear. www.medicineonline.com /druginfo/info2/Abreva/Docosanol_Topical   (859 words)

Infectious Disease News - Docosanol: OTC treatment for herpes labialis Incorporation of docosanol into the plasma membrane is believed to alter the normal membrane to inhibit the fusion of virons to the host cell. Docosanol is approved for use in adults and children older than 12 years. Docosanol is more affordable than other topical options for the recurrence of herpes labialis, and it’s unique mechanism of action may prevent the induction of drug-resistant viral mutant strains. www.infectiousdiseasenews.com /200201/pharmcon.asp   (1222 words)

Docosanol   (Site not responding. Last check: 2007-10-15) Docosanol is used to treat the symptoms of herpes simplex virus infections around the mouth. Docosanol 10% cream is a topical produced by Avanir treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). The active ingredient is docosanol, a saturated 22-carbon aliphatic alcohol, that exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV).The FDA has approved Docosanol as a non-prescribed medicine treatment for symptoms of herpes simplex virus infections. www.zwsw.com /english/show2.htm   (298 words)

[No title]   (Site not responding. Last check: 2007-10-15) Docosanol can reduce the duration of symptoms attributed to cold sores and fever blisters caused by HSV, however, docosanol is not virucidal. Docosanol exerts its action by inhibiting the fusion between the plasma membrane and the herpes simplex virus (HSV) envelope.[2925] It does not interfere with binding of HSV to HSV-specific receptors on target cells. Since docosanol does not affect the synthesis and replication of the virus, but modulates the host cell to prevent entry of the virion, development of resistance to docosanol is unlikely. www.chwframe.staywellsolutionsonline.com /modules/goldstandard/monograph.asp?cpnum=704&name=Docosanol   (760 words)

Incepta Pharma:::Products Docosanol is a 22-carbon, straight chain saturated alcohol that works by inhibiting fusion between the human cell plasma membrane and the Herpes simplex virus envelope, thereby preventing viral entry into the cells and subsequent viral replication. Docosanol cream is indicated for the topical treatment of acute and recurrent oral-facial Herpes simplex episodes (Herpes labialis or cold sores or fever blisters). Nursing Mothers: It is not known whether Docosanol is excreted in breast milk. www.inceptapharma.com /medicine/lafrost.htm   (320 words)

Docosanol -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-10-15) Docosanol 10% cream is a topical treatment for recurrent herpes simplex labialis episodes (episodes of (Caused by herpes simplex virus type 1 (HSV-1)) cold sores or fever blisters). Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent (Click link for more info and facts about viral replication) viral replication. Since the compound does not act directly on the virus, it is unlikely that it will produce drug resistant mutants of HSV. www.absoluteastronomy.com /encyclopedia/D/Do/Docosanol.htm   (128 words)

Docosanol (Topical): Drug Info: medical health network Topical docosanol is used to treat the symptoms of herpessimplex virus infections around the mouth. Children—Although there is no specificinformation comparing use of docosanol in children with usein other age groups, this medicine is not expected to causedifferent side effects or problems in children than it doesin adults. Docosanol is best used as soon as possible after thesigns and symptoms of herpes infection (for example, pain,burning, or blisters) begin to appear. medical-health-network.com /Drug_Info--Abreva--1974.html   (689 words)

Docosanol DOCOSANOL (Abreva™) skin cream treats herpes virus infections of the face and mouth. Docosanol will not cure herpes infections; it will help the sores heal faster and relieve the pain or discomfort. Docosanol skin cream is only for external use on the skin or lips; do not use in the eye. www.overlakehospital.staywellknowledgebase.com /26,704   (363 words)

MedlinePlus Drug Information: Docosanol (Topical)   (Site not responding. Last check: 2007-10-15) Docosanol (doe-KOE-san-ole) belongs to the family of medicines called antivirals. Topical docosanol is used to treat the symptoms of herpes simplex virus infections around the mouth. The dose of topical docosanol can be different for different patients. www.nlm.nih.gov /medlineplus/druginfo/uspdi/500219.html   (789 words)

Non-Prescription Abreva (Docosanol) Cream Shortens Cold Sore Healing Time   (Site not responding. Last check: 2007-10-15) Docosanol's effectiveness was proven in two large multicenter, randomized, double-blind, placebo-controlled clinical trials with 370 patients being treated with docosanol and 367 patients being treated with placebo. "Patients who were treated with docosanol at the first sign of a tingle, redness, bump or itch, saw significant reductions in the duration of pain and/or burning, itching, or tingling; the time to complete healing of classical lesions and the cessation of the ulcer/soft crust stage," said Rick Barbarash, Pharm. "Docosanol is the only non-prescription agent that has been approved by the FDA and shown to reduce healing time and the duration of symptoms in patients with cold sores," he continued. www.pslgroup.com /dg/1f519a.htm   (405 words)

Topical docosanol may be beneficial in treating HIV-related Kaposi's sarcoma   (Site not responding. Last check: 2007-10-15) WESTPORT, CT (Reuters Health) - The antiviral agent docosanol appears safe and may be effective as a topical treatment for Kaposi's sarcoma (KS) lesions in HIV-infected patients, according to the results of a pilot study published in the January 1st issue of AIDS Research and Human Retroviruses. Docosanol has shown activity against a broad spectrum of lipid-enveloped viruses in vitro, is currently approved by the US Food and Drug Administration for the topical treatment of recurrent oral-facial herpes simplex infections. On average, docosanol led to a 20% decrease in lesion area, and its efficacy was independent of anti-HIV regimen, HIV viral load, or previous KS treatments. www.aidsmeds.com /news/20010227drgd001.html   (439 words)

Abreva (Docosanol) Approved For Marketing In Canada As a result, docosanol 10% cream reduces the length of time patients experience discomfort from cold sores," said Stephen Sacks, M.D., a leading clinician and scientist in the field of antiviral therapy and founder and president of Viridae Clinical Sciences, Inc. in Vancouver, British Columbia. In pursuit of additional uses for docosanol 10% cream and to further develop its docosanol franchise, Avanir is currently evaluating the efficacy and safety in animal models of new topical formulations of docosanol that could be used to treat genital herpes. Additional indications of docosanol 10% cream that could include genital herpes and herpes zoster, also known as shingles, may also be explored under this agreement. www.docguide.com /dg.nsf/PrintPrint/211EC60D6BB6528285256BC8004551DB   (1061 words)

Dental-Professional.com - FAQs   (Site not responding. Last check: 2007-10-15) Docosanol and its metabolite (n-docosanoic acid) are present in many common foods and are virtually unavoidable in the diet. Treating cells with docosanol alters the properties of the host cell membrane in a way that inhibits or blocks, the causative agent of cold sores — the herpes simplex virus — from entering the cell via its normal pathway. Docosanol has not been tested, nor is it indicated for preventing cold sores. www.dental-professional.com /faqs.asp?SubjectID=15   (394 words)

Docosanol Topical - Talk Medical · Docosanol is an antiviral medication used to treat cold sore infections caused by the herpes simplex virus. · Docosanol Topical is used to treat cold sores on the face and lips. · Docosanol Topical should be applied at the very first sign of a cold sore, such as the tingle, redness, bump, or itch. www.talkmedical.com /medications/1941/Docosanol-Topical   (754 words)

Newly Approved Drug Therapies (627): ABREVA (docosanol), AVANIR PHARMACEUTICALS Abreva is a docosanol 10% cream for the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters). A subgroup in the trial noted that docosanol stopped cold sore episodes from progressing to the blister stage in 34% of patients who applied it at the early sign of an outbreak (redness) compared to 23% in the equivalent placebo group. Docosanol works by inhibiting fusion between the human cell plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication. www.centerwatch.com /patient/drugs/dru627.html   (626 words)

Avanir Pharmaceuticals - Product R & D - Docosanol The active ingredient is docosanol, a saturated 22-carbon aliphatic alcohol, that exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). The FDA has approved docosanol 10% cream as a treatment for cold sores and fever blisters. In addition, Abreva has significantly contributed to the 70% increase in the dollar growth of the market, and is the brand most recommended by pharmacists for the treatment of cold sores (Pharmacy Times, October 2001). www.avanir.com /product/product.php?ID=1   (489 words)

Abreva(TM) Approved for Marketing in Canada "Docosanol 10% cream has a novel mechanism of action and is most effective early in the course of an outbreak. Preliminary research findings are not always supportable by the scale-up of commercial operations, and many known and unknown risks and uncertainties could cause actual results to differ materially from those indicated in these forward-looking statements. Further, market acceptance for docosanol and other drug products is unpredictable and substantially outside of the influence and/or control of the Company. www.prnewswire.com /cgi-bin/stories.pl?ACCT=104&STORY=/www/story/05-28-2002/0001736152&EDATE=   (923 words)

Docosanol Information and Resources Online at The Drug Database - Find Useful Articles and Websites on Docosanol Right ... Docosanol 10% cream is a topical treatment for recurrent herpes simplex labialis episodes... Abreva is a docosanol 10% cream for the topical treatment of recurrent oral-facial herpes simplex... simplex episode in the 370 docosanol 10% cream-treated patients was approximately... www.thedrugdatabase.com /directory/D/Docosanol   (420 words)

IngentaConnect Docosanol: a topical antiviral for herpes labialis   (Site not responding. Last check: 2007-10-15) Docosanol is a compound with a unique mechanism of action involving viral fusion inhibition. In randomised, clinical trials, a 10% docosanol cream formulation, initiated within 12 h of symptoms onset, demonstrated efficacy in reduction of time-to-healing compared with a polyethylene glycol control. Docosanol is the first topical antiviral approved for over-the-counter use in recurrent herpes labialis. www.ingentaconnect.com /content/apl/eop/2004/00000005/00000012/art00014   (196 words)

HighBeam Research: Library Search: Results   (Site not responding. Last check: 2007-10-15) Docosanol 10% cream has a novel mechanism of action... Docosanol 10% is a topical cream discovered and... Docosanol 10% cream is intended as a topical treatment... www.highbeam.com /library/search.asp?q=Docosanol&refid=healthcyclopedia&COOKIE=NO&token=E242F54017F94043B760C2EC24A25D30   (572 words)

Docosanol (Topical) - MayoClinic.com Topical docosanol has not been studied in pregnant women. It is not known whether docosanol passes into breast milk. Although there is no specific information comparing use of docosanol in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. www.mayoclinic.com /health/drug-information/DR500219   (803 words)

Docosanol - Wikipedia, the free encyclopedia Docosanol 10% cream is a topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, Docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). This page was last modified 08:34, 10 November 2005. en.wikipedia.org /wiki/Docosanol   (170 words)

DOCOSANOL Drug and Prescription Information, Side Effects, Use, and Dosage DOCOSANOL (Topical) (Cream) is used for the Treatment Docosanol (doe-KOE-san-ole) Treats fever blisters and cold sores caused by herpes simplex. Store DOCOSANOL (Topical) (Cream) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. www.healthdigest.org /DOCOSANOL-(Topical)-(Cream)_3079_PRO.php   (323 words)

Avanir's Docosanol 10% Cream Approved for Marketing in Korea   (Site not responding. Last check: 2007-10-15) Discovered and developed by Avanir, docosanol 10% cream successfully received non-prescription status, which allows the product to be sold over-the-counter (OTC). Additional indications for docosanol 10% cream including genital herpes and herpes zoster, also known as shingles, may also be explored under the Shanghai company research agreement. To further develop its docosanol franchise, Avanir is evaluating in pre-clinical studies the efficacy and safety of new topical formulations of docosanol that could be used to treat genital herpes. www.docguide.com /dg.nsf/PrintPrint/AD6BCAAB8477F03F85256BC9004D14B8   (868 words)

Docosanol   (Site not responding. Last check: 2007-10-15) Docosanol news vertical portal can now be syndicated quickly and easily using our new Really Simple Syndication feeds. Based on the XML data format, RSS is the world's most established way to add Docosanol headlines to your site. For any further understanding that could lead to the prevention, treatment, and/or cure of the disorders, we recommend that affected individuals seek the advice or counsel of his or her own personal physician(s). docosanol.diseasemap.com /free_rss.html   (408 words)

docosanol topical side effects   (Site not responding. Last check: 2007-10-15) Each report summarizes docosanol topical interactions, docosanol topical side effects, dosing and more. It takes just minutes to learn what you need to know about docosanol topical: whether you are on a safe dose and what other hazards may exist like interactions, conflicts with other diseases you may have, duplication of therapy, reproductive hazards...all customized for you. Some other popular drug information and interaction topics this week have included: pravastatin side effects as well as EryPed side effects, Vitamin C side effects, Neurontin side effects and Norinyl 1-35 side effects. www.medicationadvisor.com /side_effects/docosanol_topical.htm   (1192 words)

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