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| | Separation of olefinic isomers - Patent 6861512 |
 | | The principle of the separation using mobile phase additives described herein, namely, the alkanes, hexane, octane, decane, and dodecane, and the 1-alkenes, 1-hexene, 1-octene, 1-decene, and 1-dodecene is not yet clearly understood. |
 | | However, it was observed for the series of compounds tested, that the presence of a carboxylic acid or a phosphate group (which contains both ionic and polar groups) correlated with the alkane and 1-alkene mobile phase additives having a positive effect on the chromatographic separation of the cis- and trans-carbon-carbon double bond isomers. |
 | | Meaningful separation of the retinal and retinal isomeric pairs was not observed either in the presence or in the absence of an alkane or 1-alkene mobile phase additive. |
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