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Topic: Dolly the sheep

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	Dolly the sheep
		When Dolly was cloned in 1996 from a cell taken from a 6 year old ewe, she became the centre of a controversy that still continues today.
		Dolly was put down on February 14, 2003, due to complications from a lung infection.
		It is arguable that Dolly is perhaps the perfect example of scientists focusing in on highly specialised areas, to such an extent that they are no longer able to see the wider picture, and for that matter, the implications of their endeavours.
	www.ebroadcast.com.au /lookup/encyclopedia/do/Dolly.html (0 words)

	Good-bye to Dolly the cloned sheep.
		Dolly's life was ended at the age of 6 (about half the life expectancy of her breed) when a veterinarian confirmed she had a progressive lung disease.
		Dolly was cloned from the udder cell of a 6-year-old adult sheep.
		Dolly did produce offspring, so if there was a genetic component to her early death the progeny will be studied to see if the detrimental effects are passed on.
	www.thelabrat.com /review/dolly.shtml (0 words)

	Cloning Sheep
		The name "Dolly" came from a suggestion by the stockmen who helped with her birth, in honour of Dolly Parton, because it was a mammary cell that was cloned.
		When Dolly was cloned in 1996 from a cell taken from a six-year-old ewe, she became the center of much controversy that still exists today.
		Dolly was a Finn Dorset lamb, created from fully differentiated adult mammary cells using a technique called somatic cell nuclear transfer; her creation was described in a Nature publication in 1997.
	www.crystalinks.com /cloningsheep.html (0 words)

	cooltech.iafrica.com \| tech news Dolly the sheep is put down
		Dolly the sheep, the first mammal to be successfully cloned from an adult cell, has been put down after she was found to have a lung disease, the Roslin Institute in Scotland's capital Edinburgh said on Friday.
		Dolly's creator, Professor Ian Wilmut, told AFP it was "perhaps slightly young" for the six-year-old sheep to contract the illness, amid concerns that she had suffered premature ageing.
		Dolly's birth in July 1996 from the breast cell of a six-year-old adult ewe made scientific history and her death at six years old had serious implications and poses deep concerns over the science of cloning.
	cooltech.iafrica.com /technews/209810.htm (0 words)

	Guardian Unlimited \| The Guardian \| Dolly the sheep is put to sleep, aged only six
		Dolly the sheep, the world's first animal to be cloned from an adult cell, has been put to sleep, it was announced yesterday.
		Dolly was born on July 5 1996, from three mothers: one ewe to provide the DNA, another to provide the egg into which the DNA was injected, and a third to carry the resulting cloned embryo to term.
		Dolly's genetic mother (the DNA was taken from an udder cell, and her name was a reference to Dolly Parton) was six when she was cloned.
	www.guardian.co.uk /uk_news/story/0,3604,895944,00.html (0 words)

	Cloning-Information on cloning,Ethics,process, Dolly sheep,against human cloning
		Dolly (A Sheep), the first mammal to be cloned from adult DNA, was put down by lethal injection Feb. 14, 2003.
		Although most Finn Dorset sheep live to be 11 to 12 years of age, postmortem examination of Dolly seemed to indicate that, other than her cancer and arthritis, she appeared to be quite normal.
		The unnamed sheep from which Dolly was cloned had died several years prior to her creation.
	www.indianchild.com /cloning.htm (0 words)

	SignOnSanDiego.com > News > Science/Health -- Cloning pioneer Dolly the sheep put to death
		LONDON – Dolly the sheep, the world's first mammal cloned from an adult, was euthanized well short of her normal lifespan after being diagnosed with progressive lung disease, her creators said Friday.
		Dolly was born July 5, 1996 in a research compound of the Scottish institute, and she created an international sensation when the achievement was announced on Feb. 23, 1997.
		Dolly, a Finn Dorset sheep named after the singer Dolly Parton, bred normally on two occasions with a Welsh mountain ram called David, first giving birth to Bonnie in April 1998 and then to three more lambs in 1999.
	www.signonsandiego.com /news/science/20030214-1021-dollydies.html (0 words)

	Creating A Cloned Sheep Named Dolly
		Dolly is not an ordinary sheep, produced through the mating of a ewe and a ram.
		Dolly is special because she disproves the notion that cells from an adult animal are too specialized to generate a new organism.
		Dolly proves that it is possible to clone an apparently healthy animal from the nucleus of an adult cell.
	science-education.nih.gov /nihHTML/ose/snapshots/multimedia/ritn/dolly/index.html (0 words)

	CNN.com - Dolly the sheep goes on display - Apr. 9, 2003
		Dolly, who drew worldwide attention when she was born in 1996, went on display at Edinburgh's Royal Museum Wednesday after being pickled and mounted.
		Dolly made shockwaves when born, a successful clone from a frozen cell taken from the mammary gland of her mother/twin who had died several years earlier.
		Dolly's skin was pickled and tanned to preserve it before being stretched over a fiberglass mould of her body, into which glass eyes were later inserted.
	www.cnn.com /2003/WORLD/europe/UK/04/09/dolly.display (0 words)

	BBC NEWS \| Science/Nature \| Dolly the sheep clone dies young
		Dolly the sheep, who became famous as the first mammal to be cloned from an adult cell, has died.
		A decision was taken to "euthanase" six-year-old Dolly after a veterinary examination showed that she had a progressive lung disease, the institute said in a statement.
		Dolly was a sheep created totally by design - even her name was picked specifically to be appealing.
	news.bbc.co.uk /1/hi/sci/tech/2764039.stm (0 words)

	Happy Dolly
		Dolly and two other cloned sheep have shorter telomeres -- the tiny strands of DNA at the end of chromosomes that scientists believe may hold the secrets to youth and aging.
		In Dolly's case the shortening was compounded because she was derived from a cell from a middle-aged animal.
		Dolly is unique, she has her own DNA set; she has her own character which is formed by both gene-gene interactions and gene-environment interactions.
	www.fortunecity.com /roswell/avebury/97/sheep.htm (0 words)

	CNN.com - First cloned sheep Dolly dies at 6 - Feb. 14, 2003
		Dolly had DNA in her cells that was typical of an older animal.
		The decision was taken to end her life at the age of 6 after a veterinary examination confirmed the lung disease, a statement from the institute said.
		Dolly, a Finn Dorset named after the country-western singer Dolly Parton, made headlines worldwide in 1996 when she became the first mammal to be cloned with DNA taken from an adult cell.
	www.cnn.com /2003/WORLD/europe/02/14/cloned.dolly.dies/index.html (0 words)

	USATODAY.com - Dolly the cloned sheep put to death (Site not responding. Last check: 2007-10-12)
		LONDON (AP) — Dolly the cloned sheep was put to death Friday, after premature aging and disease marred her short existence and raised questions about the practicality of copying life.
		The decision to end Dolly's life at age 6 — about half the life expectancy of her breed — was made because a veterinarian confirmed she had a progressive lung disease, according to the Roslin Institute, the Scottish lab where she was created and lived.
		Ian Wilmut, the leader of the team that created Dolly, said it was unlikely her illness was attributable to being a clone.
	www.usatoday.com /news/world/2003-02-14-cloned-sheep-dies_x.htm (0 words)

	Dolly the sheep dies young - 14 February 2003 - New Scientist (Site not responding. Last check: 2007-10-12)
		Dolly the sheep, the first mammal to be cloned from an adult cell, was put down on Friday afternoon, after developing a progressive lung disease.
		But as many sheep live to twice this age, her death will refuel the intense debate over the health and life expectancy of cloned animals.
		She was cloned using a cell taken from a healthy six-year-old sheep, and was born on 5 July 1996 at the Roslin Institute, Edinburgh, Scotland.
	www.newscientist.com /article.ns?id=dn3393 (0 words)

	BBC NEWS \| Science/Nature \| Goodbye Dolly
		Dolly the sheep, the first animal cloned from an adult cell, has died.
		Dolly was born in 1996 and revealed to the world in 1997, making headlines across the world.
		The fact that Dolly's genetic material came from a six-year-old sheep meant she may have aged faster than normal.
	news.bbc.co.uk /1/hi/sci/tech/2764069.stm (0 words)

	Dolly (Site not responding. Last check: 2007-10-12)
		Dolly, a sheep unremarkable except for her origin, has caused us to stop and think.
		Dolly, as the world knows, is the sheep cloned at Scotland's Roslin Institute.
		The Roslin scientists found that the human gene functioned in sheep and caused alpha-1 antitrypsin to be produced in the sheep's milk.
	www.ars.usda.gov /IS/AR/archive/may97/dolly0597.htm (0 words)

	USATODAY.com - Dolly the cloned sheep has arthritis (Site not responding. Last check: 2007-10-12)
		He said normal sheep of Dolly's age have been known to develop arthritis, but most don't until they are older.
		Dolly was born in a Scottish research compound in 1996, the world's first sheep to be successfully cloned from an adult cell.
		He also said Dolly was responding well to a treatment with anti-inflammatory drugs and that her condition will be closely monitored.
	www.usatoday.com /news/world/2002/01/04/dolly.htm (0 words)

	Dolly the sheep - Wikipedia, the free encyclopedia
		The name "Dolly" came from a suggestion by the stockmen who helped with her birth, in honor of Dolly Parton, because it was a mammary cell that was cloned
		The arthritis further fueled worry among some that this form of cloning may not be appropriate for mammals, and there is now a consensus both in- and outside scientific community that at this point the risk of unforeseen effects of cloning on the clone makes experiments in human reproductive cloning premature and unethical.
		After the cloning was successfully demonstrated by Dolly's creators once, many other large mammals have been cloned, including horses and bulls.
	www.higiena-system.com /wiki/link-Dolly_the_sheep (0 words)

	Dolly, now stuffed, goes on display - Science - MSNBC.com (Site not responding. Last check: 2007-10-12)
		Dolly’s birth in July 1996 was kept secret for months while her creators checked her lineage, but the eventual announcement, in February 1997, sent shockwaves around the world.
		Dolly was made from a frozen cell taken from the mammary gland of her mother/twin who died several years before her birth.
		While Dolly is best known for being an almost precise copy, she was in one way unique: she was the sole success of an experiment that tried to clone 276 sheep embryos.
	msnbc.msn.com /id/3077219 (0 words)

	The Scotsman - Dolly the sheep put down after growing old too soon (Site not responding. Last check: 2007-10-12)
		DOLLY the sheep, the world’s first cloned mammal, has been put down after being diagnosed with progressive lung disease.
		Dolly was born in July 1996 after being cloned from the udder cell of a six-year-old adult ewe, and named after the singer Dolly Parton.
		The cloning process to create Dolly involved transferring genetic material to an egg in the laboratory, where it was developed into an embryo and implanted into the womb of a female sheep.
	thescotsman.scotsman.com /index.cfm?id=184742003 (0 words)

	Dolly the Sheep and the GMO Agreement
		Dolly, the cloned sheep, was born in Scotland on July 5, 1996 and raised the stakes of cloning, bringing the world closer to the possibility of human cloning.
		Although Dolly is a clone, she is not a true genetic clone of one sheep, since she does not have precisely the same genetic makeup as the adult sheep she was cloned from.
		This is because Dolly’s cells, from the adult udder’s sheep, are not the same as the egg, with which it was merged.
	www.american.edu /TED/dolly.htm (4063 words)

	The Roslin Institute and Dolly the Sheep
		A decision was taken to "euthanize" six-year-old Dolly after a veterinary examination showed that she had a progressive lung disease, the institute said in a statement.
		Until then, almost all biologists thought that the cells in our bodies were fixed in their roles: the creation of Dolly from a mammary gland cell of a six year old sheep showed this was not the case and the achievement was voted Science Breakthrough of the Year at the end of 1997.
		At first Dolly was a 'clone alone' but in August 1998, a group in Hawaii published a report of the cloning of over 50 mice by nuclear transfer.
	www.martinfrost.ws /htmlfiles/roslin_dolly.html (0 words)

	Dolly the Sheep (Harpers.org)
		The leader of the research team that cloned Dolly the sheep warned against the premature cloning of farm animals for meat and milk production; cattle clones have suffered from severe defects such as diabetes, immune-system deficiencies, giant tongues, intestinal blockages, and squashed faces.
		Dolly the cloned sheep was put out of her misery.
		Dolly the sheep was stuffed and put on display at the National Museum of Scotland in Edinburgh.
	www.harpers.org /DollyTheSheep.html (0 words)

	Dolly, the famous cloned sheep! (Site not responding. Last check: 2007-10-12)
		Dolly, the famous cloned sheep represents the Holy Grail of human reproduction.
		Dolly was made from a mammary (breast) cell and showed that not only could a mammary cell make more mammary cells, but that it could make an entire lamb.
		When the DNA was taken out of the mammary cell and placed in an egg cell (ovum) from another sheep, apparently whatever is inside the egg cell caused the DNA to lose its differentiation and return to the germ cell state, capable of becoming anything, not just mammary tissue.
	www.humancloning.org /dolly.htm (0 words)

	Cloning - Wikipedia, the free encyclopedia
		Megan and Morag cloned from differentiated embryonic cells in June 1995 and Dolly the sheep in 1997.
		Dolly (1996-07-05 – 2003-02-14), a ewe, was the first mammal to have been successfully cloned from an adult cell (while the mice in USSR was cloned from embryo cell back in 1986[1]).
		The name "Dolly" came from a suggestion by Jesse Haase who helped with her birth, in honor of Dolly Parton, because it was a mammary cell that was cloned.
	en.wikipedia.org /wiki/Cloning (0 words)

	Dolly the Sheep — Infoplease.com
		Cells from the udder of a pregnant six year-old sheep were inserted into the uterus of another sheep to develop, and Dolly was born in July of 1996.
		(Her name was a sly nod to singer Dolly Parton.) Dolly had the DNA of her source, making her the first mammal successfully cloned using adult cells.
		Dolly was put to sleep in 2003 after doctors detected progressive lung disease, though she had only reached half the life span of a typical sheep.
	www.infoplease.com /biography/var/dollythesheep.html (0 words)

	Dolly in Hungary - Events - British Council Hungary (Site not responding. Last check: 2007-10-12)
		But the biggest miracle on display is likely to be Dolly - the world's first cloned mammal.
		She may be stuffed, but this sheep is the favourite in the pen as far as British biotechnology is concerned.
		Dolly usually lives in a glass case at the National Museum of Scotland, so we're pleased to see she's getting out more.
	www.britishcouncil.org /hungary-events-detail-dolly.htm (0 words)

	DJHeaf web site articles: The cloning of Dolly the sheep
		The fourth and final 'parent' of Dolly was her surrogate mother, who unlike many of the other sheep in these experiments, did not have to undergo a caesarian section.
		Dolly is thus not so much a revelation of scientific truth as a construct of the society which produced her.
		It seems so, because Dolly's genesis was funded by a grant from our government, a fact that came to public attention in the somewhat ironic circumstances of the announcement of its withdrawal shortly after the cloning story broke.
	www.heaf.freeuk.com /dolly.htm (0 words)

	Howstuffworks "Creating a Better Clone"
		PPL Therapeutics, a Scotland-based biotechnology company involved in the creation of Dolly, has produced two sheep clones whose genes have been selectively modified.
		To pinpoint the location on the sheep chromosome into which the new gene would be placed, researchers identified the flanking regions, like bookends, of the DNA that was to be replaced and the DNA to be introduced.
		Next, using the method that resulted in Dolly, the altered fibroblast cells were fused with sheep eggs from which the nuclei had been removed.
	www.howstuffworks.com /news-item60.htm (0 words)

	Education \| Cautious revolutionary
		These experiments at Roslin led to two sheep, Megan and Morag, cloned from a single embryo, and then to Dolly, cloned from a cell from the udder of a six-year-old Finn Dorset ewe.
		The nucleus of the adult cell was substituted for the nucleus of another female's egg and brought to term in the womb of a third sheep.
		Wilmut is a great ambassador, alongside Dolly, whom he once called the "friendly face of science", but years of hostile and ill-informed debate about cloning Saddam seem to have taken their toll.
	education.guardian.co.uk /print/0,3858,5246916-108966,00.html (0 words)

	Dolly: the sheep that could change our lives
		The first sheep altered using the method may be born later this year, though it will be several years before scientists will have developed the means to alter many genes simultaneously, which will be necessary to boost growth or make leaner beef.
		In earlier work, the Roslin team unveiled Megan and Morag, sheep that had been cloned by taking a cell from an early embryo, mass-producing it in the laboratory, and using these cells to "re-program" two emptied eggs.
		In this case, the resulting lamb - Dolly - was genetically identical to the sheep from which the cell was taken.
	www.telegraph.co.uk /htmlContent.jhtml?html=/archive/1997/02/24/nclo24.html (0 words)

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