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| | RAIS: Selenium (7782-49-2) (Site not responding. Last check: 2007-10-26) |
 | | Acute toxic effects observed in animals include pulmonary congestion, hemorrhages and edema, convulsions, altered blood chemistry (increased hemoglobin and hematocrit); liver congestion; and congestion and hemorrhage of the kidneys (Smith et al., 1937; Anderson and Moxon, 1942; Hopper et al., 1985). |
 | | In animals, acute inhalation exposures also result in severe respiratory effects including edema, hemorrhage, and interstitial pneumonitis (Hall et al., 1951; Dudley and Miller, 1937) as well as in splenic damage (congestion, fissuring red pulp, and increased polymorphonuclear leukocytes) and liver congestion and mild central atrophy (Hall et al., 1951). |
 | | In studies on laboratory animals, selenites or selenates have not been found to be carcinogenic; however, selenium sulfide produced a significant increase in the incidence of hepatocellular carcinomas in male and female rats and in female mice and a significant increase in alveolar/bronchiolar carcinomas and adenomas in female mice following chronic oral exposures (NCI, 1980c). |
| risk.lsd.ornl.gov /tox/profiles/selenium_f_V1.shtml (6912 words) |
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