Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Excitability of the Soma in Central Nervous System Neurons -- Safronov et al. 78 (6): 2998 -- Biophysical Journal   (Site not responding. Last check: 2007-10-20) of a spinal dorsal horn neuron from the axon and the dendritic of overshoots (+17 mV in the dorsal horn neuron and +16 mV in in the dorsal horn neuron and 1.24 pA/µm www.biophysj.org /cgi/content/full/78/6/2998   (7123 words)

Role of NO in modulating neuronal activity in superficial dorsal horn of spinal cord during exercise pressor reflex -- ...   (Site not responding. Last check: 2007-10-20) expression was observed in the superficial dorsal horn at the increased in the superficial dorsal horn of the spinal cord at Stimulation of the mesencephalic locomotor region inhibits the discharge of neurons in the superficial laminae of the dorsal horn of cats. ajpheart.physiology.org /cgi/content/full/283/3/H1012   (4674 words)

Dorsal root ganglion - Wikipedia, the free encyclopedia This is a dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium stained with anti-neurofilament antibody. The dorsal root ganglia lie along the vertebral columna by the spine. The dorsal root ganglia develop in the embryo from neural crest cells. en.wikipedia.org /wiki/Dorsal_root_ganglion   (333 words)

Somatosensory I It is an area of large cells found lateral to the dorsal columns and in the ventral corner of the dorsal horn. The infection kills dorsal root ganglia in spinal segments from sacral to lumbar ganglia. The secondary fibers from the dorsal column nuclei cross to the contralateral side and ascend to the thalamusas the medial lemniscus. thalamus.wustl.edu /Neural_Systems_03/sys_web_2003/2003/20030226Lab.htm   (2845 words)

Molecular Pain | Full text | Depression of presynaptic excitation by the activation of vanilloid receptor 1 in the rat ... In a transverse slice of the lumbar spinal cord stained with the voltage-sensitive dye, stimulation was applied to one of the dorsal roots attached to the slice, and neuronal activity in the dorsal horn region ipsilateral to the stimulated dorsal root was recorded optically. In the spinal dorsal horn, the regulation of presynaptic spiking is known in the context of presynaptic inhibition. The types of primary afferent fibers activated by the electrical stimuli were initially identified by the field potentials recorded by a glass microelectrode positioned either in the superficial dorsal horn or at the entry zone of the root, as described previously [14]. www.molecularpain.com /content/2/1/8   (6127 words)

Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord -- Ding et ...   (Site not responding. Last check: 2007-10-20) of cutaneous afferents in the dorsal spinal cord. dorsal horn neurons of wild-type and Lmx1b mutant embryos with expression of Drg11 and Ebf3 was absent in the dorsal horn of dev.biologists.org /cgi/content/full/131/15/3693   (6843 words)

Posters.html Examination of dorsal horn-specific markers at embryonic stage indicates an abnormal morphogenesis of the dorsal horn neurons. Since primary afferent-induced LTP in the dorsal horn may be one mechanism for pain sensitization, we studied the effects of 5HT on synaptic plasticity in deep dorsal horn neurons. We conclude that LTP in the dorsal horn normally probably is under a tonic descending inhibiting control and that an intact descending inhibition may inhibit LTP in WDR neurons and possibly even reduce a long lasting increase of nociception. graulab.tamu.edu /Spinal/Posters.html   (7556 words)

Current and Emerging Issues in Cancer Pain: Research and Practice In contrast, at the time when dorsal rhizotomies were being proposed as a means to relieve pain originating from a localized peripheral area, it was reported that at least three consecutive dorsal roots must be sectioned to relieve pain (72). opioid receptors in the superficial layers of the cervical dorsal horn of the spinal cord. Responses of spinal dorsal horn neurons in rats with an experimental peripheral mononeuropathy. www.painresearch.utah.edu /cancerpain/ch09.html   (8125 words)

Mechanisms of Somatic Pain A[sp[fy20,2]e[rp nociceptors terminate in the superficial dorsal horn (laminae I and II), the neck of the dorsal horn (lamina V), and in the gray matter surrounding the central canal (lamina X) (53). In the dorsal horn, CGRP appears to be restricted to primary afferent fibers (13,84,85). Responses of spinothalamic tract cells in the superficial dorsal horn of the primate lumbar spinal cord. www.painresearch.utah.edu /cancerpain/ch05.html   (5411 words)

The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord -- Müller et al. 19 (6): ...   (Site not responding. Last check: 2007-10-20) in progenitors of the dorsal or in neuronal cells of the ventral Gene expression in progenitors of the dorsal spinal cord of Olig3 mutant embryos. Brown, A.G. The dorsal horn of the spinal cord. www.genesdev.org /cgi/content/full/19/6/733   (5943 words)

Dorsal horn administration of muscimol abolishes the muscle pressor reflex -- Wilson 90 (3): 919 -- Journal of Applied ...   (Site not responding. Last check: 2007-10-20) to the dorsal surface of the spinal cord. pressor reflex synapse in the dorsal horn of the spinal cord and In summary, blocking synaptic activity in the dorsal horn of the spinal cord using muscimol abolishes the muscle pressor reflex. jap.physiology.org /cgi/content/full/90/3/919   (4233 words)

THE DISTRIBUTION OF NEUROKININ 1 RECEPTOR SP is also present in interneurones within the dorsal horn (5), and axons descending from the brainstem and terminating within the spinal cord (6). SP-containing axons form a dense plexus in LI and dorsal part of LII which is derived mainly from primary afferents, but in addition significant numbers of SP-containing axons are present in the deeper laminae of the dorsal horn, in LX and in the motor nuclei of the ventral horn. Deeper dorsal horn; NK1 receptor expressing neurones are large and in some cases, a single neurone had a dendritic arborization extending mediolateral across the whole of the dorsal horn of one side of the spinal cord. www.isrvma.org /article/55_3_3.htm   (5018 words)

Segmental effect of spinal NK-1 receptor blockade on the pressor reflex -- Wilson and Hand 275 (3): 789 -- AJP - Heart ...   (Site not responding. Last check: 2007-10-20) increases NKA release in the dorsal horn of the spinal cord. Blockade of NK-1 receptors in the dorsal horn attenuated A quantitative study of the coexistence of peptides in varicosities within the superficial laminae of the dorsal horn of the rat spinal cord. ajpheart.physiology.org /cgi/content/full/275/3/H789   (4929 words)

Pressor reflex evoked by static muscle contraction: role of nitric oxide in the dorsal horn -- Wilson et al. 276 (6): ...   (Site not responding. Last check: 2007-10-20) in the dorsal horn of the spinal cord. Evidence for involvement of N-methylaspartate receptors in "wind-up" of class 2 neurones in the dorsal horn of the rat. Attenuation of the exercise pressor reflex: effect of an opioid agonist on substance P release in the L7 dorsal horn of cats. ajpregu.physiology.org /cgi/content/full/276/6/R1639   (4598 words)

PainOnline.com: New Word on where BDNF comes from which enters the dorsal horn. The "dorsal horn" is some anatomists idea of what the Rexed layers look like on cross section when stained with a silver stain. Dorsal horn simply means the area where neurons move into the cord, and in the case of spinothalamic pain fibers, having received the input, cross over to the other side before they ascend to the thalamus (brain). BDNF originating in the dorsal root ganglion, which is the collection of cell bodies whose axons reach the skin, moves into the cord along the dorsal horn, where it wreaks havoc by eliminating the possibility of inhibition of pain by GABA(A). www.painonline.com /mt-archives/2006/03/post.html   (790 words)

Spinoreticular neurons that receive group III input are inhibited by MLR stimulation -- Degtyarenko and Kaufman 93 (1): ...   (Site not responding. Last check: 2007-10-20) There is strong neuroanatomic evidence that dorsal horn neurons project to the VLM (13, 33). is believed to arise from the dorsal horn of the spinal cord (13). Stimulation of the mesencephalic locomotor region inhibits the discharge of dorsal horn neurons responsive to muscular contraction. jap.physiology.org /cgi/content/full/93/1/92   (3881 words)

Lecture 5   (Site not responding. Last check: 2007-10-20) The motor component of the spinal nerve originates from the ventral horn of the spinal cord and leaves the spinal cord through the ventral root. The sensory neuron synapses in the dorsal horn on the interneuron, which sends information to the motor neuron in the ventral horn which tells the bicep to move. The dorsal median septum and the ventral fissure are on either side of the central canal. www.georgetown.edu /users/rgk8/neuronr5.htm   (1328 words)

Neural Plasticity Research Group Physiology and morphology of multireceptive neurons with C-afferent fiber inputs in the deep dorsal horn of the rat lumbar spinal cord. Dynamic alterations in the cutaneous mechanosensitive receptive fields of dorsal horn neurons in the rat spinal cord. Nagy I, Maggi CA, Dray A, Woolf CJ, Urban L. The role of neurokinin and NMDA receptors in capsaicin sensitive synaptic transmission in the dorsal horn of the rat spinal cord. www.mgh.harvard.edu /nprg/pubs95.htm   (1124 words)

P2X Receptor-Mediated Modulation of Sensory Transmission to the Spinal Cord Dorsal Horn -- Gu 9 (5): 370 -- The ...   (Site not responding. Last check: 2007-10-20) P2X Receptor-Mediated Modulation of Sensory Transmission to the Spinal Cord Dorsal Horn -- Gu 9 (5): 370 -- The Neuroscientist P2X Receptor-Mediated Modulation of Sensory Transmission to the Spinal Cord Dorsal Horn Endogenous ATP Involvement in Mustard-Oil-Induced Central Sensitization in Trigeminal Subnucleus Caudalis (Medullary Dorsal Horn) nro.sagepub.com /cgi/content/abstract/9/5/370   (229 words)

A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones -- MALCANGIO et al. 16 ...   (Site not responding. Last check: 2007-10-20) neurones in the dorsal horn of the spinal cord. SOM) in the dorsal horn of the spinal cord. Noxious stimuli applied to the periphery are conveyed to the dorsal horn of the spinal cord by specialized sensory neurones (nociceptors). www.fasebj.org /cgi/content/full/16/7/730   (1694 words)

subp This indicated that substance P was concentrated in the dorsal roots of mammalian spinal cord.[3] By the 1970s, the biochemical properties of purified substance P were elucidated: a proteinaceous substance composed of amino acids that, subsequently, could be synthetically derived. Intense peripheral stimulation may induce release of substance P into the dorsal horn, causing central hyperexcitability and an increased sensitivity to pain.[13] Although high concentrations of substance P are present in the dorsal horn, it is not the primary afferent transmitter, contrary to early proposals. Electrophysiologic evidence shows that iontophoretic application of substance P to dorsal horn neurons causes a delayed, slow, and prolonged excitation.[2,4] The slow response to substance P was the first evidence that excluded it as a primary afferent transmitter. fmscommunity.org /subp.htm   (3226 words)

Spinal Dorsal Horn Calcium Channel {alpha}2{delta}-1 Subunit Upregulation Contributes to Peripheral Nerve ...   (Site not responding. Last check: 2007-10-20) -1 subunit in dorsal spinal cord that correlated with neuropathic tactile allodynia -1 subunit in spinal dorsal horn ipsilateral to spinal nerve ligation injury. -1 subunit expression in dorsal spinal cord and DRG of sham and nerve-injured rats. www.jneurosci.org /cgi/content/full/24/39/8494   (3527 words)

Therapy Information Services - Neuroscience Dorsally, the floor of the fourth ventricle is formed; immediately and deep to this floor lie a number of CN nuclei. In the caudal pons, the trapezoid body is between the lemniscal fibers and the pontocerebellar fibers and indicates the crossing of the acoustic fibers from the cochlear nuclei, which ascend into the MB as the lateral lemniscus and terminate in the inf colliculus. The aqueduct divides the MB into the dorsal tectum, which consists of the inf and sup colliculi, and the ventral tegmentum, which is bounded ventrally by the crus cerebri. www.therapyedu.com /neuro/chap12.htm   (4974 words)

Title: Table Used immunofluorescence to label VR1 in the dorsal root ganglia and the spinal dorsal horn to determine the effects on primary sensory neurons. VR1 immunoreactivity was depleted in the dorsal root ganglia of the RTX treated rats, while VR1 immunoreactivity was present in small and medium sized dorsal root ganglia of control rats. In control rats, CTB was observed in all dorsal horn laminas except lamina II and in RTX-treated rats, CTB appeared to enter lamina II from lamina III. www.unr.nevada.edu /~zincze/neurobiology.htm   (1110 words)

Columbia University - Faculty Nociceptors carrying pain input from the periphery terminate in the superficial aspect of the spinal cord dorsal horn. The input travels along primary afferent axons of the dorsal root ganglia and its excitatory signal is transmitted by the release of glutamate, substance P and possibly ATP onto target dorsal horn neurons. In this laboratory, we use electrophysiological, optical, and immunocytochemical techniques to study the regulation of synaptic transmission in the superficial dorsal horn. cpmcnet.columbia.edu /dept/physio/faculty/AmyMacDermott.html   (369 words)

Zhou-Feng Chen Spinal dorsal horn is a pivotal center for integrating and relaying pain-sensing signals (nociceptive) from the periphery to the brain. In addition, we have performed genome wide profiling of the dorsal horn-enriched genes and are using gene targeting to study the function of some of identified genes in mice. Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord. dbbs.wustl.edu /dbbs/website.nsf/RIB/7C7EFC832618CE8986256D4E005B2CDC   (374 words)

Asymmetric Cross-inhibition between GABAA and Glycine Receptors in Rat Spinal Dorsal Horn Neurons -- Li et al. 278 ... Asymmetric Cross-inhibition between GABAA and Glycine Receptors in Rat Spinal Dorsal Horn Neurons -- Li et al. and Glycine Receptors in Rat Spinal Dorsal Horn Neurons dissociated neurons from rat sacral dorsal commissural nucleus. www.jbc.org /cgi/content/abstract/278/40/38637   (562 words)

PGE2 selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons - Nature ...   (Site not responding. Last check: 2007-10-20) Despite the crucial role that prostaglandins (PGs) have in the sensitization of the central nervous system to pain, their cellular and molecular targets leading to increased pain perception have remained elusive. on fast synaptic transmission onto neurons in the rat spinal cord dorsal horn, the first site of synaptic integration in the pain pathway. may facilitate the transmission of nociceptive input through the spinal cord dorsal horn to higher brain areas where pain becomes conscious. www.nature.com /neurolink/v5/n1/abs/nn778.html   (313 words)

Lecture Notes: CNS Pathways - Revised 9/18/00 There is a degeneration of the dorsal roots and columns leading to a loss of tactile and proprioceptive sensations of the pelvic limbs, ataxia and severe joint derangement Reticulospinal Tracts: Throughout the brainstem are groups of scattered nerve cells collectively known as the reticular formation- Arising from the RF are two tracts of both crossed and uncrossed fibers which descend in the lateral (medullary) and anterior (pontine) funiculi to synapse with lower motor neurons in the ventral horn. Tectospinal Tracts: These fibers arise from cell bodies in the superior colliculus of the midbrain, cross-over and descend in the ventral funiculus to synapse in the ventral horn. www.fiu.edu /~condon/pathway.htm   (948 words)

Differential effects of halothane and isoflurane on lumbar dorsal horn neuronal windup and excitability -- Cuellar et ...   (Site not responding. Last check: 2007-10-20) Differential effects of halothane and isoflurane on lumbar dorsal horn neuronal windup and excitability -- Cuellar et al. Differential effects of halothane and isoflurane on lumbar dorsal horn neuronal windup and excitability Windup in Dorsal Horn Neurons Is Modulated by Endogenous Spinal {micro}-Opioid Mechanisms bja.oxfordjournals.org /cgi/content/abstract/94/5/617   (487 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.