Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Ads by Google

Related Topics

Pain

Dorsal root ganglion - Wikipedia, the free encyclopedia This is a dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium stained with anti-neurofilament antibody. In anatomy and neurology, the dorsal root ganglion is a nodule on a dorsal root that contains cell bodies of afferent spinal nerve neurons. All of the axons in the dorsal root convey somatosensory information. en.wikipedia.org /wiki/Dorsal_root_ganglion   (117 words)

Rat Dorsal Root Ganglia Neurons - Cambrex In the absence of mitotic inhibitors, the neurons tend to cluster (ganglionate) and detach from the substrate. A ganglion is a group of nerve cells forming a nerve center, especially one located outside the brain or spinal cord. Dorsal Root Ganglion, also called Spinal Ganglion, is the ganglion of the posterior root of each spinal segmental nerve, containing the cell bodies of the unipolar primary sensory neurons. www.cambrex.com /prod.ratDRG   (259 words)

ePrintsUQ - Vulnerability of the Dorsal Root Ganglion in Experimental Allergic Encephalomyelitis The dorsal (posterior) root ganglion is a relatively neglected part of the nervous system from the clinical point of view. In recent studies on the pathophysiology of experimental allergic encephalomyelitis (EAE), the main animal model of multiple sclerosis, the DRG of the rabbit was shown to be the site of extensive inflammation and demyelination and of focal conduction block in a high proportion of the large diameter afferents. The vulnerability of the DRG is due to a deficient blood-nerve barrier and possibly also to a susceptibility of the branch point of the ganglion neurone to demyelination-induced conduction block. eprint.uq.edu.au /archive/00000725   (257 words)

Diabetes: Morphometry of dorsal root ganglion in chronic ... @ HighBeam Research   (Site not responding. Last check: 2007-10-22) Morphometry of dorsal root ganglion in chronic experimental diabetic neuropathy. The histogram of the diabetic DRG has a narrower small neuron peak, with a slight left-shift, with the division between large and small neurons remaining unchanged; an area of 1,500 [micro][m.sup.2] (diameter 20 [micro]m) separates large clear (type A) from small dark (type B) neurons qualitatively in both diabetic and control samples. Earlier pathological studies on spinal roots (10) and dorsal root ganglion showing demyelination, vacuolar degeneration, and pigmentary changes (11) have been supported by recent pathophysiological studies supporting the sensory neuron as a target and, in particular, the mitochondrion as the most relevant organelle. highbeam.com /library/doc0.asp?DOCID=1G1:84209429&...   (3484 words)

ePrintsUQ - Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - ... Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - A Histological and Electrophysical Study The DRG was the most affected region of the PNS and its involvement increased caudally. Originally published as M. Pender and T.A. Sears (1986) Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - A Histological and Electrophysiological Study, Journal of the Neurological Sciences, 72 (2-3): 231-242. eprint.uq.edu.au /archive/00002294   (284 words)

The expression and distribution of tau proteins and messenger RNA in rat dorsal root ganglion neurons during ... These isoforms are still present in all dorsal root ganglion neurons in neonates, whereas high molecular weight tau isoforms are expressed in a subset of dorsal root ganglion neurons. In the adult, high molecular weight tau is restricted to small- and medium-sized dorsal root ganglion neurons; its distribution largely coincides with the population of substance P and calcitonin gene related peptide peptidergic neurons. This differential distribution was observed in the cell body, dorsal roots and sciatic nerve axons. www.arclab.org /medlineupdates/abstract_7644032.html   (359 words)

Journal of Bone and Joint Surgery: Dorsal root ganglion neurones with dichotomising afferent fibres to both the lumbar ... Dorsal root ganglion neurones with dichotomising afferent fibres to both the lumbar disc and the groin skin: A possible neuronal mechanism underlying referred groin pain in lower lumbar disc diseases Dorsal root ganglion neurones with dichotomising axons are present in several species and are After immersion of the DRGs in the same fixative overnight at 4 deg C, and storage in 0.01 M phosphate buffered saline containing 20% (WN) sucrose for 24 hours at 4 deg C, we prepared 40 (mu)m sections using a cryostat. www.findarticles.com /p/articles/mi_qa3767/is_200305/ai_n9258272   (1231 words)

Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity   (Site not responding. Last check: 2007-10-22) Neurotoxicity was assessed by L5 dorsal root ganglion morphometry and H-reflex-related sensory nerve conduction velocity. Platinum concentrations in dorsal root ganglia and plasma were measured by inductively coupled plasma mass spectrometry. Dorsal root ganglion nucleolus size was significantly increased following single doses of paclitaxel of 10 and 20 mg kg www.nature.com /bjc/journal/v88/n12/abs/6601012a.html   (317 words)

Dorsal Root Ganglion In this slide of a section through a dorsal root ganglion, observe the large, pale staining ganglion cells. In pseudounipolar neurons, one axon divides close to the cell body into two processes, one of which becomes a "functional dendrite" (although it actually is a myelinated axon). The dorsal root ganglion is encapsulated in condensed C.T. that is continuous with the sheath of the peripheral nerves that enter and leave it. www3.umdnj.edu /histsweb/lab8/lab8DRG.html   (590 words)

Theses uitgebreid Uematsu's technique of radiofrequency thermocoagulation of the dorsal root ganglion was considered to be a relatively simple technique that could relieve pain and preserve motor function and proprioception. An RF-lesion made inside the dorsal root ganglion resulted in an indiscriminate destruction of nervous tissue, when viewed by light microscopy in HE-stained sections, two weeks after the lesion was made. These changes were not observed in a dorsal root ganglion when the lesion was made adjacent to the dorsal root ganglion and viewed using the same technique and timespan. www.fdg.unimaas.nl /anesthesiology/theses_uitgebreid.htm   (14766 words)

Membrane Potential Oscillations in Dorsal Root Ganglion Neurons: Role in Normal Electrogenesis and Neuropathic Pain -- ... DRG neurons were categorized by axon conduction velocity (CV) and the shape of the intracellularly recorded spike. Puil E, Spigelman I (1988) Electrophysiological responses of trigeminal root ganglion neurons in vitro. Rizzo MA, Kocsis JD, Waxman SG (1994) Slow sodium conductances of dorsal root ganglion neurons: intraneural homogeneity and interneuronal heterogeneity. www.jneurosci.org /cgi/content/full/19/19/8589   (5454 words)

Axon Regeneration The dorsal root ganglia that was not injected had no regeneration of the injured axons. The dorsal root ganglia that was injected with saline, had very little growth of the injured axons into the regions of the lesions. The dorsal root ganglia that was injected with db-cAMP, had growth of the injured axons. www.unr.nevada.edu /~chan2   (984 words)

Morphogenic Role for Acetylcholinesterase in Axonal Outgrowth during Neural Development   (Site not responding. Last check: 2007-10-22) DRG neuronal cultures were prepared from E-15 rat embryos as previously described (17-22). DRG neurons displayed a dose-dependent reduction in outgrowth in the presence of either BW284c51 or physostigmine (Figure 2). Inverse correlation of acetylcholinesterase (AChE) activity with the presence of neurofilaments inclusions in dorsal root ganglion neurons cultured in the presence of a reversible inhibitor of AChE. ehp.niehs.nih.gov /members/1999/Suppl-1/81-87bigbee/bigbee-full.html   (3929 words)

Cisplatin-Induced Apoptosis in Rat Dorsal Root Ganglion Neurons Is Associated with Attempted Entry into the Cell Cycle ... DNA from enriched DRG neuronal cultures was isolated by modification of a previous method (45). Konings, P.N.M., W.K. Makkink, A.M.L. van Delft, and G.S.F. Ruigt (1994) Reversal by NGF of cytostatic drug-induced reduction of neurite outgrowth in rat dorsal root ganglia in vitro. Moonen (1994) Image analysis of neuritic regeneration by adult rat dorsal root ganglion neurons in culture: quantification of the neurotoxicity of anticancer agents and of its prevention by nerve growth factor or basic fibroblast growth factor but not brain-derived neurotrophic factor or neurotrophin-3. www.jci.org /cgi/content/full/101/12/2842   (6589 words)

Traction of the lumbar spine for radicular low back pain 1988), the ramifications of extraneural inflammation in the IVF are vascular compromise inducing intraneural oedema in the DRG. Reduction in mechanical irritation from venous congestion around the DRG may be an explanation for the efficacy of a treatment technique such as traction. Reduced mechanical irritation of the DRG in the IVF may be responsible for the immediate and long lasting effects of the appropriate treatment for acute radicular pain, in some people. www.acay.com.au /~mkrause/traction.htm   (5259 words)

The Arginine-Rich Hexapeptide R4W2 Is a Stereoselective Antagonist at the Vanilloid Receptor 1: A Ca2+ Imaging Study in ... DRG cell cultures from days 2 to 4 were loaded for 50 to 60 min at 37°C in the dark with the cell permeant acetoxymethyl ester Savidge JR, Ranasinghe SP and Rang HP (2001) Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor VR1. Wardle KA, Ranson J and Sanger GJ (1997) Pharmacological characterization of the vanilloid receptor in the rat dorsal spinal cord. jpet.aspetjournals.org /cgi/content/full/301/3/981   (4168 words)

Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy -- Everill ... Burchiel, K. Spontaneous impulse generation in normal and denervated dorsal root ganglia: sensitivity to the alpha-adrenergic stimulation and hypoxia. Devor, M., and Wall, P. Cross-excitation in dorsal root ganglia of nerve-injured and intact rats. Stansfeld, C. Fagni, L., Marsh, S. Brown, D. and Feltz, A. Kinetics of the dendrotoxin-sensitive K current in dissociated dorsal root ganglion (DRG) neurons of the rat (Abstract). jn.physiology.org /cgi/content/full/82/2/700   (5768 words)

British Journal of Pharmacology - Local anaesthetics block hyperpolarization-activated inward current in rat small ...   (Site not responding. Last check: 2007-10-22) in the membrane of dorsal root ganglion neurones (DRG). In the tissue slice of the DRG, a dense population of DRG cells with apparently no connective tissue between the cells was seen under the microscope. Next, the effects of bupivacaine on the voltage response of DRG neurones to injected current pulses were investigated (Figure 6). www.nature.com /bjp/journal/v139/n7/full/0705363a.html   (5313 words)

[No title] Cannabinoid 1 receptor-mediated presynaptic inhibition of synaptic transmission in the dorsal horn of the spinal cord Nagy I; Dray A; Urban L; (12/12/1995)  "Possible branching of myelinated primary afferent fibres in the dorsal root of the rat. Nagy I; Urban L; Woolf CJ; (23/04/1993)  "Morphological and membrane properties of young rat lumbar and thoracic dorsal root ganglion cells with unmyelinated axons. www1.imperial.ac.uk /med/people/i.nagy.html   (3146 words)

Morphometry of Dorsal Root Ganglion in Chronic Experimental Diabetic Neuropathy -- Kishi et al. 51 (3): 819 -- Diabetes (10) and vacuolar degeneration of DRG neurons (11)—have DRG neurons in the rat and cat (16,21). neurofilament phosphorylation of dorsal root neurons and sural diabetes.diabetesjournals.org /cgi/content/full/51/3/819   (3181 words)

Peripheral Inflammation Sensitizes P2X Receptor-Mediated Responses in Rat Dorsal Root Ganglion Neurons -- Xu and Huang ... Grubb BD, Evans RJ (1999) Characterization of cultured dorsal root ganglion neuron P2X receptors. Labrakakis C, Gerstner E, MacDermott AB (2000) Adenosine triphosphate-evoked currents in cultured dorsal root ganglion neurons obtained from rat embryos: desensitization kinetics and modulation of glutamate release. Stanfa LC, Kontinen VK, Dickenson AH (2000) Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats. www.jneurosci.org /cgi/content/full/22/1/93   (6494 words)

Spinal   (Site not responding. Last check: 2007-10-22)  Their axons travel through the dorsal root into the gray matter of the cord.  the ventral and dorsal rootlets unite to form the spinal nerve. symptoms are caused by pressure or inflammation of the spinal cord or nerve roots. www.bonniemyer.com /Spinal.html   (2197 words)

Single-channel Properties of Recombinant Acid-sensitive Ion Channels Formed by the Subunits ASIC2 and ASIC3 from Dorsal ...   (Site not responding. Last check: 2007-10-22) Bevan, S., and Yeats, J. Protons activate a cation conductance in a sub-population of rat dorsal root ganglion neurons. Lingueglia, E., De Weille, J.R., Bassilana, F., Heurteaux, C., Sakai, H., Waldmann, R., and Lazdunski, M. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. Zeilhofer, H.U., Kress, M., and Swandulla, D. Fractional Ca currents through capsaicin- and proton-activated ion channels in rat dorsal root ganglion neurons. www.jgp.org /cgi/content/full/117/6/563   (5402 words)

Low-Threshold, Persistent Sodium Current in Rat Large Dorsal Root Ganglion Neurons in Culture -- Baker and Bostock 77 ... Large dorsal root ganglion (DRG) neurons would be expected to support the largest-diameter somatosensory axons, analogous Primary cultures of neurons were prepared from the lumbar DRGs of male Wistar rats (200-300 g). A high proportion of dissociated DRG neurons appears almost round in culture, and it is therefore quite easy to estimate an jn.physiology.org /cgi/content/full/77/3/1503   (6323 words)

Diabetes: Morphometry of dorsal root ganglion in chronic ... @ HighBeam Research   (Site not responding. Last check: 2007-10-22) Our sampling is appropriate, and the appropriate correction factors have been used. There are additional studies that support pathophysiologically important changes in DRG neurons with resultant axonal alterations. DRG blood flow is reduced (11, 26), and there is impaired neurotrophic support (31). highbeam.com /library/doc0.asp?docid=1G1:84209429&refid=ink_tptd_mag   (3484 words)

Profile The laboratory has begun investigating the biophysical and pharmacological properties of GABA receptors located on human adult and embryonic dorsal root ganglion cells. Department of Veterans Affairs: Neurosteroids and GABA receptors on human DRG neurons, 180,000/yr, Apr 1, 2002 to Mar 30, 2006. Hackman JC, Davidoff RA, Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions, Neuroscience, 41(1), 61-9, 1991 myprofile.cos.com /hackmanj22   (937 words)

Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations Energy Citations Database (ECD) Document #6213889 - The critical period for peripheral specification of dorsal root ganglion neurons is related to the period of sensory neurogenesis Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. The critical period for peripheral specification of dorsal root ganglion neurons is related to the period of sensory neurogenesis www.osti.gov /energycitations/product.biblio.jsp?osti_id=6213889   (124 words)

ASIC3 [Amiloride-sensitive Cation Channel 3; TNaC1; Testis Sodium Channel 1; Dorsal Root Ganglion ASIC (DRASIC)] , ... ASIC3 [Amiloride-sensitive Cation Channel 3; TNaC1; Testis Sodium Channel 1; Dorsal Root Ganglion ASIC (DRASIC)], control peptide for AB5678P : AG352 Please click here to select your location, to view pricing Optimal working concentration must be determined by the end user. www.chemicon.com /Product/ProductDatasheet.asp?ProductItem=AG352   (117 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.