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Topic: Doxylamine


In the News (Wed 16 Dec 09)

  
  Doxylamine facts and comparsions at Drugs.com
Doxylamine may be taken with or without food.
Doxylamine is not recommended for use in CHILDREN younger than 12 years of age.
Doxylamine is to be used only by the patient for whom it is prescribed.
www.drugs.com /cdi/doxylamine.html   (1070 words)

  
  Doxylamine succinate (IARC Summary & Evaluation, Volume 79, 2001)
Doxylamine succinate is an ethanolamine-based antihistamine used in the management of insomnia and, in combination with antitussives and decongestants, in the relief of cough and cold symptoms.
Doxylamine induces thyroxine glucuronidation in mice, with concomitant decreases in serum thyroxine and increases in serum thyroid stimulating hormone concentrations.
Doxylamine succinate induced DNA damage in primary rat hepatocytes and inhibited intercellular communication, but it did not induce sister chromatid exchange in mammalian cells in culture or induce mutations in bacteria.
www.inchem.org /documents/iarc/vol79/79-05.html   (0 words)

  
 FIRST PHARM - Product Abflex
Doxylamine succinate has anticholinergic properties and should be used with care in conditions such as glaucoma and prostatic hyportrophy.
Doxylamine succinate may mask the warning symptoms of damage caused by ototoxic drugs and may effect the metabolism of drugs in the liver.
Overdosage of DOXYLAMINE SUCCINATE (an antihistamine) causes sedation.
www.firstpharm.co.za /Abflex.htm   (973 words)

  
 Nausea and Vomiting of Pregnancy - July 1, 2003 - American Family Physician
A single 25-mg doxylamine (Unisom) tablet taken at night can be used alone or in combination with pyridoxine (25 mg three times daily).
In the 1970s, a medication combining pyridoxine and doxylamine (Bendectin) commonly was used to treat women with nausea and vomiting of pregnancy.
doxylamine should not be taken by pregnant women or women who are nursing a baby; however, some research supports its efficacy and safety.
www.aafp.org /afp/20030701/121.html   (3426 words)

  
 Doxylamine - Drug information from Medic8.com
Doxylamine succinate is one of the many sedating antihistamines used by itself as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug, and a preparation is prescribed in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
In a study, it was found that doxylamine succinate is possibly more effective than the barbiturate, phenobarbital for use as a sedative.
Doxylamine succinate is a potent anticholinergic and has a side-effect profile common to such drugs (including drymouth, ataxia, urinary retention, and drowsiness).
www.medic8.com /medicines/Doxylamine.html   (0 words)

  
 MEDLINE Search on Medscape.com
Doxylamine is an antihistamine of the ethanolamine class.
Doxylamine succinate is an antihistaminic drugwith additional hypnotic, anticholinergic and local anesthetic effects first described in 1948.
Doxylamine succinate, an over-the-counter antihistamine, is commonly used as a nighttime sleep aid in the short-term management of insomnia.
search.medscape.com /medline-search?queryText=Doxylamine   (399 words)

  
 Are NyQuil nights more wasted than drunken nights
Doxylamine succinate is the active ingredient in Nyquil and other over-the-counter antihistamines which are used commonly as a sleep aids and which also contain antitussive and decongestant agents for relieving cold and flu symptoms.
They reported an observation of severe rhabdomyolysis in association with doxylamine overdose and warranted a high index of suspicion and evaluation for further complications in antihistamine toxicity, especially with the great number of nonprescription drugs containing doxylamine which are available to the general public.
Their results suggest that doxylamine is an inducer of liver microsomal cytochrome P450 in B6C3F1 mice, and so exposure to doxylamine also resulted in decreases in serum thyroxine levels with compensatory increases in serum thyroid-stimulating hormone level.
healthpsych.psy.vanderbilt.edu /NyquilR.htm   (1241 words)

  
 Data Sheet
Doxylamine succinate is a white or creamy white powder with a characteristic odour and has solubilities of approximately 1 g/mL in water and 500 mg/mL in alcohol at 25°C. It has a pKa of 5.8 and 9.3.
The safety and efficacy of doxylamine as a night time sleep aid in children younger than 12 years of age have not been established.
Haemodialysis, haemofiltration and peritoneal dialysis have not been studied in the treatment of doxylamine overdose but are unlikely to be effective in view of the high volume of distribution.
www.medsafe.govt.nz /profs/Datasheet/d/Dozilecap.htm   (0 words)

  
 Doxylamine - Wikipedia, the free encyclopedia
It is also the most effective over-the-counter sedative available in the United States, and more sedating than some prescription hypnotics.
For this reason, doxylamine has sometimes been used off label in a manner similar to diphenhydramine for the reduction of anxiety symptoms.
The dosage required to induce hypnosis (sleep) can be as low as 6.25 mg, but is usually effective in dosages of up to 25 mg.
en.wikipedia.org /wiki/Doxylamine   (353 words)

  
 Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine Information on Healthline
Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine may cause dizziness or drowsiness.
Doxylamine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.
Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine is used to treat nasal congestion, sinusitis (inflammation of the sinuses), runny nose, watery eyes, headache, body aches, and coughs associated with allergies, hay fever, and the common cold.
www.healthline.com /multumcontent/apap-dextromethorphan-doxylamine-pse   (0 words)

  
 Doxylamine Succinate
Chemistry - An ethanolamine-derivative antihistamine, doxylamine succinate occurs as a white to creamy-white powder with a characteristic odor.
Doxylamine succinate has solubilities of 0.5 g/ml in alcohol and 1 g/ml in water.
Doxylamine is also contraindicated in patients who are hypersensitive to it or other antihistamines in its class.
www.elephantcare.org /Drugs/doxylami.htm   (527 words)

  
 Syndol
Doxylamine is known as a sedating antihistamine because it enters the brain, where it causes drowsiness.
Paracetamol and doxylamine are not known to be harmful when used during pregnancy.
Doxylamine may also pass into breast milk, but its effects on a nursing infant are unknown.
www.netdoctor.co.uk /medicines/100002516.html   (1605 words)

  
 Unisom (doxylamine) and vitamin B6 for morning sickness
Doxylamine is the most proven, safe, and effective medication available for reducing nausea and vomiting during pregnancy.
and doxylamine was prescribed as Bendectin in the U.S. until 1983, when it was taken off of the market; it has continued to be available in Canada as Dilectin.
Although Bendectin was once thought to cause fetal problems, this medication is now considered to have one of the best safety profiles of all medications given during pregnancy, based on the tens of millions of women treated since 1956 with no known fetal effects.
www.webmd.com /hw/health_guide_atoz/tn9124.asp   (217 words)

  
 Drugs and Treatments - Sleep Tablet (Doxylamine) Oral - Patient Handout from RxList
Doxylamine is an antihistamine used as a sleep aid.
Before taking doxylamine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
It should not be used during the last 3 months of pregnancy since antihistamines may increase the risk of serious side effects in a newborn baby (e.g., seizures).
www.rxlist.com /drugs/drug-57139-Sleep+Tablet+(Doxylamine)+Oral.aspx?drugid=57139&drugname=Sleep+Tablet+(Doxylamine)+Oral   (0 words)

  
 Drugs and Treatments - Sleep Aid (Doxylamine) Oral - Patient Handout from WebMD
Doxylamine is an antihistamine used as a sleep aid.
Before taking doxylamine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
It should not be used during the last 3 months of pregnancy since antihistamines may increase the risk of serious side effects in a newborn baby (e.g., seizures).
rxlist.com /drugs/drug-89032-Sleep+Aid+(Doxylamine)+Oral.aspx?...+Oral   (1130 words)

  
 acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine
You may not be able to take acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Symptoms of an acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine overdose include a dry mouth, large pupils, flushing, sweating, nausea, vomiting, diarrhea, abdominal pain, seizures, confusion, an irregular heartbeat, hyperactivity, or hallucinations.
Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants.
www.ghc.org /kbase/entireTopic.jhtml?docId=d03349a1   (0 words)

  
 Birth Defects Research for Children, Inc.
The other active ingredient in Bendectin is Decapryn (doxylamine succinate), an antihistamine which belongs to a group called ethanolamines, the most potent and highly sedative of the antihistamines.
Doxylamine is structurally similar to another ethanolamine, Benadryl.
When doxylamine was applied directly to these cells, it interfered with the proper growth and differentiation of the mouse limb bud.
www.birthdefects.org /Research/bendectin2.htm   (3421 words)

  
 Eniva Vitamins, Minerals, Electrolyte Water, and Nutiritional Supplements Doxylamine
Doxylamine is an antihistamine used for short-term treatment of
Doxylamine is available alone in a nonprescription product for sleep and in combination with nonprescription drugs to treat symptoms of
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb.
www.vitamin-galore.com /Drug/Doxylamine.htm   (421 words)

  
 Doxylamine
lymph doxylamine nodes is limited to the early phase of pulmonary infection.
Teenage patients presented with symptoms of malaise, myalgia, chill, and rigor similar to those seen in adults, whereas the younger children presented mainly doxylamine with a cough and runny nose, and none had chills, rigor, or myalgia.
It states that efficacy is generally comparable between doxylanmine classes and within classes and that the doxylamime initial doxylamine selection will largely be based on the anticipated side effects for an individual patient, patient preference, quantity and quality doxyllamine of clinical trial data regarding the medication, and its cost.
fmaks.info /doxylamine   (1205 words)

  
 Doxylamine
DOXYLAMINE (Unisom® Sleeptabs™) is an antihistamine commonly used as a nighttime sleep aid.
If you take doxylamine to help you sleep, take the dose no more than once per day about 30 minutes before bedtime.
Doxylamine may cause dry eyes and blurred vision.
www.stjohn.org /HealthInfoLib/swArticle.aspx?26,2421   (0 words)

  
 LENAPAIN TABLETS
Doxylamine succinate may also produce antimuscarinic effects including blurred vision, difficulty in micturition, dysuria, dryness of the mouth and tightness of the chest.
Doxylamine succinate may precipitate epileptiform seizures in patients with local lesions of the cerebral cortex.
Doxylamine should be used with care in the elderly, and in conditions such as closed-angle glaucoma, urinary retention, liver impairment, prostatic hypertrophy or pyloroduodenal obstruction.
www.intekom.com /pharm/lennon/lenapain.html   (1349 words)

  
 Doxylamine
Doxylamine is an antihistamine used for short-term treatment of
Doxylamine is available alone in a nonprescription product for sleep and in combination with nonprescription drugs to treat symptoms of
Antihistamines, including doxylamine, can cause “anticholinergic”; side effects such as dryness of mouth and heart palpitations.
www.pccnaturalmarkets.com /health/Drug/Doxylamine.htm   (378 words)

  
 doxylamine - OneLook Dictionary Search
We found 4 dictionaries with English definitions that include the word doxylamine:
Tip: Click on the first link on a line below to go directly to a page where "doxylamine" is defined.
doxylamine : The On-line Medical Dictionary [home, info]
www.onelook.com /?w=doxylamine   (76 words)

  
 Doxylamine
Doxylamine is an antihistamine used for short-term treatment of insomnia.
Doxylamine is available alone in a nonprescription product for sleep and in combination with nonprescription drugs to treat symptoms of allergy, colds, and upper respiratory infections.
Antihistamines, including doxylamine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations.
www.publix.com /wellness/notes/Display.do?id=Drug&childId=Doxylamine   (402 words)

  
 Doxylamine - [Alternative Medicine]
Doxylamine is an antihistamine used for short-term treatment of insomnia.
Doxylamine is available alone in a nonprescription product for sleep and in combination with nonprescription drugs to treat symptoms of allergy, colds, and upper respiratory infections.
Antihistamines, including doxylamine, can cause "anticholinergic" side effects such as dryness of mouth and heart palpitations.
www.peacehealth.org /kbase/cam/hn-1367008.htm   (0 words)

  
 Consumer Reports Medical Guide - Doxylamine
Doxylamine, an antihistamine, causes drowsiness as a side effect and is used in the short-term treatment of insomnia.
Do not give doxylamine to a child younger than 12 years of age unless directed to do so by a doctor.
Do not take doxylamine if you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] in the last 2 weeks.
www.consumerreports.org /mg/drug-reports/doxylamine.htm   (728 words)

  
 Doxylamine - Drugs & Vitamins - Drug Library - DrugDigest
Take doxylamine with food or milk if it upsets your stomach.
You should not take doxylamine to help you sleep for more than 2 weeks without first consulting your health care professional.
Tell your prescriber or health care professional if you are taking doxylamine for cold or allergy symptoms and there is no improvement in 1 or 2 days, or if you develop a high fever, have difficulty breathing, or your symptoms worsen.
www.drugdigest.org /DD/DVH/Uses/0,3915,227|Doxylamine,00.html   (0 words)

  
 Pharmacy: Doxylamine Succinate
I had been taking Doxylamine Succinate (Unisom) tablets for years (finally stopped for good about a week ago), & am wondering if the years of drugged sleep could've caused the dark circles under my eyes.
Although doxylamine is OTC and considered safe it is still not innocuos.
There are muscarinic and cholinergic receptors in the brain as well as histamine receptors that have been bathing in doxylamine for months.
en.allexperts.com /q/Pharmacy-1407/Doxylamine-Succinate.htm   (982 words)

  
 Insomnia relief - causes and treatments for falling and staying asleep at MedicineNet.com
Diphenhydramine (e.g., Sominex, Nytol) and doxylamine (e.g., Unisom) are the two antihistamines that are currently marketed as OTC sleep aids.
Scientists believe that diphenhydramine and doxylamine cause sedation by blocking the action of histamine in the brain, but the exact mechanism of action is not known.
Diphenhydramine and doxylamine also cause constipation, dry mouth, and difficulty urinating.
www.medicinenet.com /sleep_aids_and_stimulants/page2.htm   (997 words)

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