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Topic: EMLA

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	Virtual Hospital: P & T News (Site not responding. Last check: 2007-11-02)
		EMLA cream (lidocaine 2.5% and prilocaine 2.5%) is an emulsion in which the oil phase is a eutectic mixture of lidocaine and prilocaine in a ratio of 1:1 by weight.
		EMLA cream may not be as effective in reducing anxiety associated with a procedure as it is in reducing pain.
		EMLA cream should not be used in infants less than one month of age or in infants under the age of 12 months who are receiving treatment with methemoglobin-inducing drugs since the risk of significant methemoglobinemia is increased in these populations.
	www.vh.org /adult/provider/pharmacyservices/PTNews/1994/11.94.html (3278 words)

	Pediatrician Visits Pain Free!
		EMLA Cream (lidocaine 2.5% and prilocaine 2.5%) is indicated as topical anesthetics for use on normal intact skin for local analgesia (pain relief).
		EMLA is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type or any other component of the product.
		EMLA is indicated for genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anesthesia.
	www.lapregnancy.com /scoops_m-q/pediatrician_visits_pain_free.htm (402 words)

	EHS: WOW-Topical Local Anesthetics: a comparison of ELA-Max and EMLA (Site not responding. Last check: 2007-11-02)
		EMLA is a prescription topical anesthetic emulsion cream that is applied to the skin and covered with an occlusive dressing for at least 60 minutes (depending on the required depth of penetration).
		EMLA (for 60 minutes) and ELA-Max (for 30 minutes) were randomly applied to each hand before the procedure.
		ELA-Max and EMLA with or without occlusion have similar efficacy at 5, 15, 30, and/or 60 minutes in children (N=147) for venipuncture pain and in adults for pain from gentle pinpricks (N=19) and from TCH application (N=10).
	www.mosbysdrugconsult.com /WOW/pu082.html (2361 words)

	Environmental Management and Law Association (Site not responding. Last check: 2007-11-02)
		EMLA has gone to the courtroom in over 50 cases each year for individuals and communities who have been victims of environmental injustices.
		EMLA has worked with government at all levels, including such projects as the Local Environmental Action Program (LEAP) which provides a framework within which local governments learn to manage their environmental assets and responsibilities.
		EMLA attorneys are also found teaching on environmental law and other topics in several Budapest universities including the ELTE Faculty of Law, the Pázmány Péter Catholic University, and the Central European University.
	www.emla.hu /newsite/1_1.html (550 words)

	Hairfacts: EMLA topical anesthetic
		EMLA is a thick white cream with very little smell and a rather bitter taste.
		EMLA was developed by Swedish pharmaceutical Astra (now part of Merck) and is only available in the U.S. by prescription.
		EMLA comes in 5 and 30 gram ointment tubes, with the 30-gram tube usually around $40.
	www.hairfacts.com /tips/pain/emla.html (796 words)

	Duke Children's Hospital & Health Center: Preparing Your Child for Special Procedures
		EMLA cream is a prescription medication which is used to help prevent the pain when an IV line is placed or during an injection (for a blood test or shot).
		EMLA cream is placed on the skin and is covered with a clear dressing.
		EMLA should be used with caution in patients less than 1 year of age since infants may have an increased risk of methemoglobinemia.
	dukehealth1.org /childrens_services/special_procedures.asp (822 words)

	El Mirage Ladies Auxiliary (Site not responding. Last check: 2007-11-02)
		The EMLA is a group of women that are dedicated to the support of the Land Speed Racers and their families when disasters arise.
		The overall purpose of the EMLA is to give emergency financial assistance to the families.
		The EMLA is independent of the SCTA and BNI or any particular club within the organizations.
	www.scta-bni.org /EMLA/emla2_5.htm (284 words)

	EHS: WOW-Guidelines for Using EMLA
		EMLA may be applied at home and may need to be kept on longer in persons with dark and/or thicker skin.
		In the United States, EMLA is approved for use in infants 37 weeks of gestational age and older.
		EMLA is contraindicated in anyone with a known history of sensitivity or allergy to amide-type local anesthetics (lidocaine, prilocaine, mepivacaine, bupivacaine, etidocaine) or to any other component of the product.
	www3.us.elsevierhealth.com /WOW/op022aaa.html (662 words)

	EMLA Cream 5% , SPC from the eMC
		EMLA Cream should not be applied to genital mucosa in children.
		EMLA, like other local anaesthetics may be ototoxic and should not be instilled in the middle ear nor should it be used for procedures which might allow penetration into the middle ear.
		The use of EMLA prior to measles-mumps-rubella or intramuscular diptheria-pertussis-tetanus-inactivated poliovirus-Haemophilus influenzae b or Hepatitis B vaccines does not affect mean antibody titres, rate of seroconversion, or the proportion of patients achieving protective or positive antibody titres post immunization, as compared to placebo treated patients.
	emc.medicines.org.uk /emc/assets/c/html/displaydoc.asp?documentid=171 (932 words)

	AAP: Infants Treated with EMLA® (lidocaine/prilocaine) Cream Before Lumbar Puncture Experience Less Trauma (Site not responding. Last check: 2007-11-02)
		EMLA® (lidocaine 2.5 percent and prilocaine 2.5 percent) for topical analgesia relieves the pain associated with skin puncture, according to researchers led by Alla Shenkman, MD, from the Pediatric Emergency Department at Our Lady of Mercy Medical Center, in New York, New York, United States.
		The use of EMLA was associated with a lower risk of TLP (0.31, 95 percent, confidence interval [CI]: 0.13 - 0.73, p=0.006).
		The stratification analysis for age showed that the use of EMLA was protective for traumatic lumbar puncture for 29 of 37 children younger than 60 days (odds ratio [OR]: 0.30, 95 percent, CI: 0.12 - 0.75) and in 10 of 11 60 days or older (OR: 0.32, 95 percent, CI: 0.03 - 3.39, p=0.0031).
	www.pslgroup.com /dg/221322.htm (450 words)

	Hairfacts: Whealton, 1998 (EMLA and iontophoresis)
		EMLA has been shown to be useful in a variety of primary care procedures, including superficial biopsies.
		When EMLA is applied to atopic or psoriatic skin, its anesthetic effect is quicker, and there are higher, but less than toxic, levels of the lidocaine and prilocaine in the circulation.
		EMLA cream-induced allergic dermatitis: a role for prilocaine as an immunogen.
	www.hairfacts.com /medpubs/pain/whealton.html (1387 words)

	New Simple Treatment Available to Reduce Pain in Children During Routine Shots and Injections
		EMLA, which can be conveniently applied at home by parents prior to visits to the doctor or in office or clinical settings, is useful in a variety of needle procedures including IV placement, port access, blood and lab draws, lumbar punctures and superficial skin surgery.
		EMLA, applied to intact skin under a closed dressing, provides dermal pain relief by the release of lidocaine and prilocaine into the epidermal and dermal layers of the skin and the accumulation of lidocaine and prilocaine in the vicinity of dermal pain receptors and nerve endings.
		EMLA is not recommended for use on mucous membranes, and it is contraindicated for patients with a known history of sensitivity to local anesthetics of the amide type or to any other component of the product.
	www.kidsource.com /kidsource/content4/painfree.shots.html (830 words)

	children with DIABETES - EMLA Cream to be Taken Off the Market
		EMLA is an anesthetic cream often used by insulin pumpers to numb the skin prior to inserting an insulin pump infusion set.
		EMLA is being taken off the market because the packaging doesn't comply with the Poison Prevention Packaging Act.
		EMLA will no longer be available at pharmacies or to physicians for use in their offices.
	www.childrenwithdiabetes.com /d_0j_216.htm (226 words)

	Procedures & Techniques
		EMLA is a cream that is applied to the skin under a tegaderm for 1-2 hours prior to a painful procedure.
		EMLA (Eutectic Mixture of Local Anaesthetics, with Eutectic meaning that the resultant mixture has greater effect than the mere sum of its parts) is available by prescription only.
		Alternatively, I believe that EMLA can be left on for up to 4 hours for major procedures (please check this in the insert.) You could try leaving it on for 3 hours, in which case you'd have vasodilation, which may ease the whole procedure".
	www.cystic-l.org /handbook/html/procedures_techniques.htm (2653 words)

	New use patent for 1) EMLA and 2) Elamax for post-cryotherapy anesthesia (Site not responding. Last check: 2007-11-02)
		Abstract: Topical anesthetics, EMLA and Elamax, are currently approved, indicated and recommended for pre-surgical anesthesia of normal intact skin.
		EMLA and Elamax has been used and proven to provide effective and faster anesthesia when applied to skin lesions treated by cryotherapy (frozen and liquid nitrogen).
		EMLA and Elamax have proven to be effective when used as a post-cryotherapy anesthesia.
	www.research.drexel.edu /techcom/engine.asp?deva=ForInvestors.HealthScience.030488 (366 words)

	About EMLA Anesthetic Disc (Site not responding. Last check: 2007-11-02)
		EMLA is a unique product that numbs your child's skin at the injection site and makes needle insertions and other procedures less painful.
		EMLA can only be prescribed by your child's doctor, but can easily be applied at home before the procedure.
		You can use EMLA for repeated procedures in the same place on his or her skin without the skin becoming permanently numb.
	www.emla-us.com /facts (510 words)

	Rxsubmit.com - Emla (Site not responding. Last check: 2007-11-02)
		EMLA: Peel away the protective liner and place the disc on the procedure site, usually 1 hour before the procedure or as directed by your doctor.
		Caution is advised when prescribing or using EMLA in the elderly since they may be more sensitive to the effects of the drug.
		EMLA should not be used in infants under 1 month of age.
	rxsubmit.com /emla.html (534 words)

	EMLA Cream Safe & Effective (But Caution in the First Three Months ofLife)
		EMLA may be of little or no use in reducing the pain of heel pricks or venepuncture in newborn infants up to 3 months.
		EMLA should be used with caution in infants because of reports of methaemoglobinaemia.
		EMLA cream must be applied at least 60 minutes before procedures involving intact skin, and covered with an occlusive dressing (details are on the package insert).
	www.medsafe.govt.nz /Profs/PUarticles/EMLA.htm (606 words)

	Pain of circumcision, pain control
		EMLA (Eutectic Mixture of Local Anesthetics): This topical anesthetic cream from Astra Pharma is much touted for relief of circumcision pain, but studies show that it is only slightly effective for that purpose.
		EMLA cream is not approved for use in the first thirty days of life due to the threat of methemoglobinemia, a blood disease.
		The package insert from the manufacturer states that EMLA should not be used on mucosal tissue (which would rule out its use for circumcision), and in any case should not be used on children under 12 months of age, because of the risks of its use.
	www.cirp.org /library/pain (2548 words)

	University of Iowa PSRC EMLA (Lidocaine and Prilocaine Cream) Information (Site not responding. Last check: 2007-11-02)
		In areas of high blood flow, time to onset may be delayed and effectiveness reduced secondary to the medication being taken up into the vasculature.
		EMLA is approved for use on intact skin in infants as young as 37 weeks gestational age.
		The size and age of the patient determine the amount of cream that can be safely applied and the maximum application time.
	anesthesia.uihc.uiowa.edu /proceduralsedation3/adult/EMLA.asp (506 words)

	A Systematic Review of Lidocaine-Prilocaine Cream (EMLA) in the Treatment of Acute Pain in Neonates -- Taddio et al. ... (Site not responding. Last check: 2007-11-02)
		EMLA was administered to 21 preterm neonates (7 to
		The efficacy of EMLA for decreasing pain from venipuncture was assessed in two studies involving 127 procedures (Table 1).
		Randomized Controlled Study The efficacy of EMLA in alleviating the pain from LP was investigated in one study (Table 1).
	pediatrics.aappublications.org /cgi/content/full/101/2/e1 (5274 words)

	[No title] (Site not responding. Last check: 2007-11-02)
		EMLA COMPLICATIONS ---------------------------------------------------- Dear colleagues, like they say, if you've done it long enough, the statistics are going to catch up with you.
		Now, the insert for EMLA says that in about 1% there may be a rash.
		I applied the EMLA on the face because I was going to remove their dermatosis papulosa nigrans.
	matrix.ucdavis.edu /rxderm-archives/emla-complication (660 words)

	Hairfacts: Romsing, 1999 (EMLA/tetracaine)
		We have evaluated the anaesthetic effect of tetracaine gel 1 g, applied for 45 min, compared with EMLA cream 2 g, applied for 60 min, in a randomized, double-blind study in 60 children aged 3-15 yr.
		Venous cannulation was performed 15 min after removal of the EMLA cream (n = 20) and tetracaine gel (n = 20).
		We conclude that tetracaine gel provided effective, rapid, long-lasting and safe local anaesthesia, and was significantly better than EMLA cream in reducing pain during venous cannulation in children using the recommended application periods for both formulations.
	www.hairfacts.com /medpubs/pain/romsing.html (191 words)

	EHS: WOW-EMLA approved for newborns, available in disc, and relieves pain of chest tube removal
		Since EMLA cream was first approved for use in the United States in 1993, the pediatric indication was over 1 month of age.
		The new lower age limit removes the objection to using EMLA on newborns for common procedures, such as circumcision, intramuscular injections of vitamin K and hepatitis B vaccine, and heel lancing for genetic testing or bilirubin levels.
		In a study of parental application of EMLA cream at home, parents rated the placement of the occlusive dressing (Tegaderm) as the most difficult part of the procedure.
	www.mosbysdrugconsult.com /WOW/pu051.html (662 words)

	Emla Cream
		EMLA (eutectic mixture of lidocaine and prilocaine) cream is currently not recommended for use in infants
		There are insufficient data to support the use of EMLA cream for circumcision in newborn infants at this time.
		EMLA cream is presently not recommended for use on genital skin or mucosa." Dosage and Administration: "Use in infants under the age of 6 months: Not recommended" "DO NOT APPLY EYES OR ON OPEN WOUNDS.
	www.circumcisionquotes.com /emla.html (587 words)

	Neuroscience Products
		When EMLA is applied to normal intact skin for an hour, the skin at the application site becomes numb.
		EMLA® Cream is available in 5 gram and 30 gram tubes.
		EMLA® is not recommended for use on mucous membranes.
	www.accolateinfo.com /content/products/productDisplay.asp?id=30 (255 words)

	Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers: [Un gel de ...
		Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers: [Un gel de piroxicam, compare a une creme EMLA, est associe a moins de douleur apres une canulation veineuse chez des volontaires] -- Dutta et al.
		Occurrence of erythema and edema with EMLA or with piroxicam
		EMLA® cream versus ethyl-chloride spray: a comparison of the analgesic efficacy in children.
	www.cja-jca.org /cgi/content/full/50/8/775 (1342 words)

	Pediatrics: EMLA toxicity after application for allergy skin testing.@ HighBeam Research (Site not responding. Last check: 2007-11-02)
		EMLA (eutectic mixture of local anesthetics) is a eutectic mixture of lidocaine and prilocaine used to provide topical anesthesia for various procedures.
		When used properly, EMLA can provide anesthesia to a depth of 5 mm in intact skin, allowing for better pain control during superficial procedures (eg, venipuncture and lumbar puncture).
		The adverse effects most commonly related to the use of EMLA are mild local reactions such as edema, erythema, and transient pallor.
	www.highbeam.com /library/doc0.asp?DOCID=1G1:113646370&refid=holomed_1 (207 words)

	EMLA: The BME Encyclopedia (Site not responding. Last check: 2007-11-02)
		EMLA is an acronym for Eutectic Mixture of Local Anesthetics.
		When EMLA is applied to normal intact skin for an hour under an anaerobic bandage (which means that it needs to be isolated from the air during activation — this is done either by a
		It should be noted that while EMLA cream is over-the-counter in Canada, it is a prescription-only substance in most countries, including the US.
	encyc.bmezine.com /?EMLA (234 words)

	Can EMLA cream be used for pain relief during circumcision?
		This concern was stemmed from previous observations that EMLA use may have caused mild forms methemoglobinemia in newborns.
		EMLA cream is effective at decreasing the pain associated with circumcision although it was not felt to be as effective as using the dorsal penile nerve block technique.
		In addition, EMLA is a prescription medication, so unless your moyel is a physician, he probably will not be able to obtain it.
	parenting.ivillage.com /newborn/ncare/0,,3q4z,00.html (575 words)

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