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Topic: EPSP


In the News (Sat 11 Oct 08)

  
  Excitatory postsynaptic potential - Wikipedia, the free encyclopedia
In neuroscience, an excitatory postsynaptic potential (EPSP) is a temporary increase in postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell.
Larger EPSPs result in greater membrane depolarization and thus increase the likelihood that the postsynaptic cell reaches the threshold for firing an action potential.
The neurotransmitter most often associated with EPSPs is the amino acid glutamate, and is the main excitatory neurotransmitter in the central nervous system.
en.wikipedia.org /wiki/EPSP   (665 words)

  
 Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases - Patent 5310667
If a variant of EPSP synthase could be identified that had a high K.sub.i for glyphosate and a lower K.sub.m for PEP than the current variant, it would enhance the ability to achieve glyphosate tolerance in plant species or plant tissues where it is difficult to engineer a high level of gene expression.
The EPSP synthase clone is then altered by oligonucleotide mutagenesis to insert the DNA substitution necessary to result in the alanine for glycine substitution in the first conserved amino acid sequence and an aspartic acid for glycine substitution in a second conserved amino acid sequence as previously described.
The DNA was hybridized with a nick-translated EPSP synthase sequence from pMON9531 in a Southern blot procedure.
www.freepatentsonline.com /5310667.html   (18206 words)

  
 Title of Invention: Glyphosate-tolerant 5-enolpyruv yl-3-phosphoshikimate synthase
The glyphosate-tolerant EPSP synthases are prepared by substituting an alanine residue for a glycine residue in a conserved sequence found between positions 80 and 120 in the mature wild-type EPSP synthase.
The nucleotide sequence for the mutant E. coli EPSP synthase aroA gene was determined by the method of Sanger (1977) and the corresponding amino acid sequence for the encoded EPSP synthase deduced therefrom.
Hence, for purposes of the present invention glyphosate-tolerant EPSP synthase polypeptides produced by substituting an alanine for the second glycine in a sequence homologous to the sequence (-L-G-N-A-G-T-A-) located between positions 80 and 120 is considered an equivalent of the present discovery and therefore within the scope of the invention.
www.nal.usda.gov /bic/Biotech_Patents/1994patents/05312910.html   (15235 words)

  
 BioMed Central | Full text | Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber ...
EPSPs were recorded from CA1 neurons in rat hippocampal brain slices in response to Schaffer-collateral fiber stimulation.
EPSPs were depressed to comparable levels by TTX (60 nM) or lowered stim, but facilitation was not changed, indicating a simple failure of axonal conduction.
Fiber volley and EPSP amplitudes were measured from peak negative voltage to baseline (minimum-to-baseline) or alternatively, their initial slopes were measured between 20% and 80% of minimum.
www.biomedcentral.com /1471-2202/7/5   (4603 words)

  
 EPSP Synthase
EPSP synthase was first purified as described by Lewendon and Coggins (20), but the method has since been improved through the use of a better vector employing the T7 promotor in E.
In the forward direction, EPSP synthase can be coupled with chorismate synthase, the enzyme in the Shikimate pathway which converts EPSP to chorismate; as EPSP synthase produces EPSP, chorsimate synthase can convert EPSP to chorismate which can be detected at 275 nm (20).
Since EPSP synthase can also proceed in the reverse direction, activity can also be assayed with coupling to pyruvate kinase and lactate dehydrogenase which oxidize NADH in the breakdown of pyruvate, allowing the detection of NADH loss at 340 nm which corresponds to pyruvate evolution by EPSP synthase (20).
www.arches.uga.edu /~gpries/bcmb8010/isolation.htm   (497 words)

  
 Background Synaptic Conductance and Precision of EPSP-Spike Coupling at Pyramidal Cells -- Zsiros and Hestrin 93 (6): ...
D, left:, the change of the EPSP half-width at depolarized potential relative to its half-width at the resting potential are plotted when current was injected (open bar; 3.0 ± 0.3, n = 16 experiments) and when conductance was injected (filled bar; 1.4 ± 0.1, n = 16).
Middle: the increase of EPSP amplitude at depolarized potential relative to its amplitude at resting potential when current was injected (open bar; 1.6 ± 0.1, n = 16 experiments) and when conductance was injected (filled bar; 1.5 ± 0.1, n = 16).
Right: the change of EPSP rise time at depolarized potential relative to the rise time at the resting potential are plotted when current was injected (open bar; 1.8 ± 0.1, n = 16 experiments) and when conductance was injected (filled bar; 1.3 ± 0.2, n = 16).
jn.physiology.org /cgi/content/full/93/6/3248   (6158 words)

  
 Grant Thornton LLP in Canada | Management Issues Papers | Employee Profit Sharing Plan (EPSP) can benefit business ...
An EPSP is an arrangement whereby an amount is paid to a trustee (or trustees) to be held for the benefit of some or all of your employees.
The epsp trust is exempt from tax and is not required to file a return.
An EPSP could be established so that the amount that would otherwise be paid as a bonus to the owner-manger is paid to the EPSP.
www.grantthornton.ca /mgt_papers/MIP_template.asp?MIPID=130   (727 words)

  
 Behavioral Neuroscience: EPSP & IPSP
Please remember that, like our model neuron, the following description is not how things really work, but it may help you to get a picture of the events which will then allow you to explore the information in more detail and revise and correct your understanding.
The vote is more than 2/3 in favor but there was not a quorum (not enough EPSPs) so the message is not sent.
Since the vote is not more than 2/3 in favor, the message is not sent.
www.indiana.edu /~iuepsyc/bn/materials/epsp-ipsp.htm   (1033 words)

  
 EPSP Amplitude Modulation at the Rat Ia-Alpha Motoneuron Synapse: Effects of GABAB Receptor Agonists and Antagonists -- ...
EPSP Amplitude Modulation at the Rat Ia-Alpha Motoneuron Synapse: Effects of GABAB Receptor Agonists and Antagonists -- Peshori et al.
The amplitudes of composite EPSPs were measured in a total of 103 motoneurons in response to 18 Hz stimulation (Fig.
of monosynaptic EPSPs in lumbosacral motoneurones of the anaesthetized
jn.physiology.org /cgi/content/full/79/1/181   (5155 words)

  
 EPSP Synthase
synthase (EPSPS) is one of two enzymes in the class of enolpyruvyltransferases.
EPSP synthase is involved in the shikimate pathway, using phosphoenolpyruvate (PEP) to convert shikimate-3-phosphate (S3P) to 5-enolpyruvyl-3-shikimate phosphate (Fig.
The purpose of this report is to summarize the function and importance of EPSP sythase and its interaction with substrates and the synthetic inhibitor glyphosate as well as to detail the structural aspects of these relationships.
gpries.myweb.uga.edu /bcmb8010   (477 words)

  
 Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of ...
EPSPs, we quantified the amplitude of the spinous Ca transient when the AP preceded the EPSP by 50 ms (Fig.
by an EPSP in the sequence AP-EPSP or an AP in the sequence EPSP-AP (Fig.
The reduction in fluorescence change evoked by an EPSP in the sequence AP-EPSP compared with that evoked by a single EPSP alone is illustrated by the difference between the shaded area and the thick line (second trace from bottom).
www.pnas.org /cgi/content/full/95/16/9596   (4598 words)

  
 Avoid Payroll Taxes with EPSP
However, recently the EPSP has gained considerable popularity with the new legislation of sec 120.4 regarding what is commonly referred to as the "kiddie tax" on split income from family trusts.
In order to continue qualifying as an EPSP, the trustee of the EPSP must annually allocate, either contingently or absolutely, all of the EPSP income, capital gains and employer contributions to the employees who are beneficiaries of the EPSP.
In order to establish an EPSP, documents relating to the establishment of the trust, including a Deed of Settlement for the employees profit sharing plan trust, and all related corporate resolutions should be prepared and executed by the appropriate parties.
www.blairgoates.com /photo2.html   (730 words)

  
 Control of Feedforward Dendritic Inhibition by NMDA Receptor-Dependent Spike Timing in Hippocampal Interneurons -- ...
H, EPSP kinetics as a function of EPSP amplitude: notice the similar size of fast (filled circles) and slow (filled triangles) EPSPs and the lack of correlation.
EPSP is attributable to a large spread of a single kinetic population
A summary plot of EPSP half width is shown after stimulation of stratum lacunosum-moleculare (L), the border between stratum lacunosum-moleculare and stratum radiatum (L/R), and stratum radiatum (R).
www.jneurosci.org /cgi/content/full/22/13/5462   (7450 words)

  
 Mechanism of Chorismate Synthase: ROLE OF THE TWO INVARIANT HISTIDINE RESIDUES IN THE ACTIVE SITE -- Kitzing et al. 279 ...
The time course of the generation of chorismate from EPSP is shown in experiments with wild-type NcCS and the two single histidine mutant proteins, as indicated in the graph.
MOPS buffer, pH 7 and 25 °C, in the absence of EPSP.
Binding of EPSP to the H17A and H106A mutant proteins in the presence of oxidized FMN.
www.jbc.org /cgi/content/full/279/10/9451   (5149 words)

  
 [No title]   (Site not responding. Last check: 2007-10-21)
I wish to thank all our partners for the fruitful cooperation and express the conviction that our cooperation will continue in a fruitful way also in the future for our common objective of enhancing the capabilities of the private sector to contribute more significantly to reducing unemployment and poverty in the country.
Finally I express my high appreciation for the hard and dedicated efforts of all my colleagues and counterparts from EPSP as well as our colleagues from CIM and DED, whose contribution is indispensable for the work of EPSP.
Highlights of her visit were meetings with the EPSP programme manager, staff, counterparts, MTEVT officials and a field trip to Taiz.
www.epspye.com   (2230 words)

  
 Bidirectional plasticity of excitatory postsynaptic potential (EPSP)-spike coupling in CA1 hippocampal pyramidal ...
EPSP slopes and population spike (PS) amplitudes were measured.
After HFS, a given EPSP slope evoked a larger PS (superimposed blue and red traces).
After LFS a given EPSP slope evoked a smaller PS (superimposed red and green traces).
www.pnas.org /cgi/content/full/99/22/14512   (3573 words)

  
 Title of Invention: Glyphosate-tolerant 5-enolpyruv yl-3-phosphoshikimate synthases
The petunia EPSP synthase cDNA clone can be expressed in E. coli to produce a fully functional EPSP synthase enzyme when the cDNA clone is properly tailored for expression in E.
EPSP synthase, the wild-type EPSP synthase coding sequence in phage M9568 was mutagenized with the oligonucleotide.
napus EPSP synthase gene is isolated and inserted into a plant transformation vector similar to pMON987 described hereinbefore.
www.nal.usda.gov /bic/Biotech_Patents/1994patents/05310667.html   (18305 words)

  
 Profit Sharing Plans
Under the Income Tax Act (Canada), an Employee Profit Sharing Plan allows participating employees, usually corporate executives, to receive income from the corporation without either the employee or the company being subject to payroll levies such as Canada Pension Plan contributions and Employment Insurance contributions.
Ideal for self-employed corporate owners and for older corporate executives, an EPSP allows participating employees to take advantage of this ability for up to seven years without losing benefits because of the 15% drop-out rule.
The EPSP allows corporate executives to receive payments from the corporation without being subject to payroll levies (CPP and EI contributions) (Sec.
www.serre.ca /MAP-Assist/epsp_root.html   (170 words)

  
 GBL Inc. - Employee Profit Sharing Plan (EPSP)
GBL Inc. - Employee Profit Sharing Plan (EPSP)
Established under section 144 of the Income Tax Act, the EPSP is a special purpose trust that allows the beneficiaries of the plan to share in the profits of the company
How it Works A trust called The Employee Profit Sharing Plan for XYZ Company is set up using a three person trust agreement.
www.gblinc.ca /products/epsp.html   (206 words)

  
 Integrated Ocean Drilling Program
Integrated Ocean Drilling Program - EPSP: Environmental Protection and Safety Panel
Guidelines for EPSP safety review report and presentation, and expedition safety package (326.89 KB)
If you experience any difficulties on this website, please contact the Webmaster.
www.iodp.org /epsp   (362 words)

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