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Topic: Eflornithine

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	eflornithine - Womens Health and Medical Information on MedicineNet.com (Site not responding. Last check: 2007-11-03)
		Eflornithine is believed to block ODC and thereby slow the growth and differentiation of the cells within the hair follicles.
		PRESCRIBED FOR: Eflornithine is used to slow hair growth on the face and chin in women ages 12 and older.
		Eflornithine should not be washed away from the skin for at least eight hours after application.
	www.medicinenet.com /eflornithine/article.htm (537 words)

	eflornithine topical - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-11-03)
		Eflornithine topical is in the FDA pregnancy category C. This means that it is not known whether eflornithine topical will harm an unborn baby.
		Eflornithine topical is usually applied twice daily, at least eight hours apart, or as directed by your doctor.
		Eflornithine topical may cause temporary redness, rash, burning, stinging, or tingling, especially if it is applied to broken or irritated skin.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100107221 (1257 words)

	EFLORNITHINE HYDROCHLORIDE Drug Information EFLORNITHINE HYDROCHLORIDE
		This compound is not known to be metabolized and is primarily excreted unchanged in the urine.
		VANIQA (eflornithine hydrochloride) Cream, 13.9% is indicated for the reduction of unwanted facial hair in women.
		Eflornithine did not elicit mutagenic effects in an Ames reverse-mutation assay or clastogenicity in primary human lymphocytes, with and without metabolic activation.
	www.drugs.com /pdr/EFLORNITHINE_HYDROCHLORIDE.html (3100 words)

	New lease of life for resurrection drug
		The supply of eflornithine, nicknamed the ‘resurrection drug’ because of its spectacular effect on comatose patients in late stage gambiense sleeping sickness, may at last be assured.
		Eflornithine was discovered in 1980 by Dr Cyrus Bacchi, Pace University, New York, through a TDR-supported study on polyamine metabolism in trypanosomes (the causative organism of sleeping sickness).
		This study demonstrated that, in mice, eflornithine was effective against the enzyme ornithine decarboxylase, a key enzyme in the multiplication of trypanosomes.
	www.who.int /tdr/publications/tdrnews/news64/eflornithine.htm (398 words)

	AAD: Eflornithine Hcl 15% Cream Slows Excessive Growth Of Facial Hair
		The Eflornithine HCl cream 15% Phase III studies were conducted to evaluate the safety and efficacy of the topical cream in the treatment of women with excessive facial hair.
		The data from the two studies show that overall 70 percent of patients improve, and 35 percent of participants in the Eflornithine HCl group are rated as clinical successes (marked improvement or clear/almost clear) compared to nine percent in the vehicle group.
		The significant difference between participants on Eflornithine HCl cream 15% and those on vehicle was seen as early as after four weeks of treatment (P=0.017) in one study and after eight weeks of treatment (P is less than or equal to 0.001) in the second study.
	www.docguide.com /dg.nsf/PrintPrint/4640882642D5E4CF8525689E006D75B8 (730 words)

	Vaniqa / Cushing's Help and Support
		Do not use eflornithine topical without first talking to your doctor if you are breast-feeding a baby.
		Apply a thin layer of eflornithine topical to the affected areas of the face and nearby affected areas under the chin and rub it in thoroughly.
		You may not be able to use eflornithine topical, or you may require a dosage adjustment or special monitoring during treatment.
	www.cushings-help.com /vanqua-monograph.htm (1012 words)

	Eflornithine Cream Approved by FDA as Treatment for Unwanted Facial Hair / Cushing's Help and Support (Site not responding. Last check: 2007-11-03)
		Regardless of the cause, eflornithine cream demonstrated in clinical trials that it is effective in slowing the growth of unwanted facial hair in up to 60% of women.
		Eflornithine takes up to 2 months to work, and along with eflornithine, women should continue to use their current method of hair removal.
		Eflornithine is believed to work by blocking an enzyme that is necessary for hair growth.
	www.cushings-help.com /eflornithine.htm (516 words)

	Eflornithine hydrochloride. DermNet NZ
		Eflornithine administered by injection is used to treat African sleeping sickness, a disease caused by protozoa (tiny one-celled animals).
		Eflornithine HCl cream is indicated for the reduction of unwanted facial hair in women.
		Eflornithine HCl cream slows the rate of hair growth and is often used in combination with other hair removal techniques to maintain a hair-free complexion.
	dermnetnz.org /treatments/eflornithine.html (496 words)

	AAD: Eflornithine Helps Women Battle Excessive Facial Hair
		Eflornithine (HC1 cream) 15% is a new topical cream that has been shown to significantly reduce the rate of excessive facial hair growth in women.
		At the end of the 24-week studies, physicians assessed that the women treated with the eflornithine (HC1 cream) 15% showed significant improvement in the reduction of facial hair growth compared to the group that was treated with the control.
		Eflornithine (HC1 cream) 15% was recently approved by the U.S. Food and Drug Administration for treating excessive facial hair growth in women.
	www.docguide.com /dg.nsf/PrintPrint/71DC967FC810EA6785256931006857AD (826 words)

	MedlinePlus Drug Information: Eflornithine
		Eflornithine is used to slow the growth of unwanted hair on the face in women, usually around the lips or under the chin.
		Eflornithine works by blocking a natural substance that is needed for hair to grow and is located in your hair follicle (the sac where each hair grows).
		To help you remember to apply eflornithine cream, apply it around the same times every day, such as in the morning and in the evening.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a604031.html (792 words)

	Eflornithine - Wikipedia, the free encyclopedia
		Eflornithine appears to kill trypanosomes by acting as a suicide inhibitor of the enzyme ornithine decarboxylase (EC 4.1.1.17), this enzyme regulates cell division by catalysing the first step in polyamine biosynthesis.
		Eflornithine's effects against Trypanosoma brucei gambiense were discovered by chance and because its ability to bring patients back from coma, it became known as "Resurrection Drug".
		As of September 2005, the World Health Organization's eflornithine page is reporting that the India Institute of Chemical Technology in Hyderabad, India and ILEX Oncology in Texas, United States are both working on new ways of making eflornithine more cheaply.
	en.wikipedia.org /wiki/Eflornithine (606 words)

	Eflornithine
		Eflornithine is also an effective hair removal agent and is the active ingredient in Vaniqa brand hair removal cream.
		As of September 2005, the World Health Organization's eflornithine page is reporting that the India Institute of Chemical Technology in Hyderabad, India and ILEX Oncology in Texas, United States are both working on new ways of making eflornthine more cheaply.
		The WHO goes on to say that ILEX is experimenting with an oral formulation of the drug as a treatment for cancer and that trials of the new oral formulation for efficacy against sleeping sickness are underway.
	www.mrsci.com /Parasitology/Eflornithine.php (464 words)

	Vaniqa - Drugs & Vitamins - Drug Library - DrugDigest (Site not responding. Last check: 2007-11-03)
		Eflornithine injection is for infusion into a vein.
		Eflornithine is usually given in the hospital for severe infections.
		Eflornithine is usually given in a hospital or clinic setting.
	www.drugdigest.org /DD/DVH/Uses/0,3915,550121\|Vaniqa,00.html (527 words)

	Treatments for Unwanted Facial Hair
		Eflornithine 13.9% cream is a topical treatment that does not remove the hairs, but acts to reduce the rate of growth and appears to be effective for unwanted facial hair on the mustache and chin area.
		Eflornithine 13.9% cream can be used in combination with other treatments such as lasers and IPL to give the patient the best chance for successful hair removal.
		Eflornithine HCl 13.9% cream is an irreversible inhibitor of ornithine decarboxylase, an enzyme that has been associated with the prolongation of the anagen or growth phase of the hair.
	www.skintherapyletter.com /2005/10.10/1.html (1451 words)

	MedlinePlus Drug Information: Eflornithine (Topical) (Site not responding. Last check: 2007-11-03)
		Eflornithine (ee–FLOOR–nith–een) is used to slow down bodily substances called enzymes that help hair grow.
		Children—There is no specific information comparing use of eflornithine in children under the age of 12 years with use in other age groups.
		However, this medicine is not expected to cause different side effects or problems in older children than it does in adults.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/500227.html (835 words)

	#1. EFLORNITHINE - free sample vaniqa, vaniqa-cream, product vaniqa, order vaniqa - Maintenance Mode Enabled
		eflornithine - On most areas of the butalbital adalat body, hair is "peach fuzz" - thin, fine hair that is called "vellus" hair.
		You may not see eflornithine improvement for the first month of use.
		eflornithine - On most areas cialis levita of the body, hair is "peach fuzz" tramadol online paracetamol - thin, fine hair that is called "vellus" hair.
	xph25eflornithi.proboards92.com (461 words)

	Eflornithine (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-11-03)
		Eflornithine (ee-FLOR-ni-theen) is used to treat African sleeping sickness, a disease caused byprotozoa(tiny one-celled animals).
		However, studies in animals have shown that eflornithine causes death of the fetus and birth defects.
		Eflornithine can lower the number of white blood cells in your blood, increasing the chance of getting an infection.
	www.mayoclinic.com /health/drug-information/DR202609 (971 words)

	Eflornithine (Topical) - MayoClinic.com (Site not responding. Last check: 2007-11-03)
		Studies with eflornithine have not been done in pregnant women.
		It is not known whether eflornithine passes into breast milk.
		There is no specific information comparing use of eflornithine in children under the age of 12 years with use in other age groups.
	www.mayoclinic.com /health/drug-information/DR500227 (853 words)

	Eflornithine for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency ...
		Eflornithine for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: a preliminary review.
		Eflornithine is an antiprotozoal agent active against P. carinii.
		Eflornithine has been used on a compassionate basis in AIDS patients with PCP who were intolerant of or unresponsive to traditional agents.
	www.aegis.com /aidsline/1989/jun/M8960096.html (408 words)

	Guide to Hair Removal - Eflornithine HCl 13.9% Cream, VANIQA (via CobWeb/3.1 planetlab2.isi.jhu.edu) (Site not responding. Last check: 2007-11-03)
		Eflornithine hydrochloride 13.9% cream is a permanent inhibitor of ornithine decarboxylase, an enzyme that has been associated with the prolongation of the anagen or growth phase of the hair.
		After 24 weeks of treatment in clinical trials, it was shown to be effective on the upper lip and chin.
		Clinical observations identified hair loss as a side-effect of eflornithine therapy and led to the development of Vaniqa, which gained US regulatory approval in July 2001, as the first and only prescription cream clinically proven to slow the growth of unwanted facial hair in women.
	www.guidetohairremoval.com.cob-web.org:8888 /eflornithine-hcl-cream/index.html (220 words)

	Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy.
		Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy.
		Eflornithine (DFMO) was used to treat 31 AIDS patients with confirmed Pneumocystis carinii pneumonia who had clinically failed treatment with pentamidine, sulphamethoxazole-trimethoprim or both agents as their first-line therapy.
		Eflornithine appears to be a useful salvage therapy in patients failing first-line treatments.
	www.aegis.com /aidsline/1991/apr/M9140590.html (323 words)

	About eflornithivnx2 - Home
		eflornithine - Vaniqa has not been approved for use by children younger than 12 years of age.
		No warranty, eflornithine either expressed or implied, is made in regards to this information.
		EFLORNITHINE - TOPICAL (eh-FLOOR-nith-een) COMMON BRAND NAME(S): Vaniqa USES: This medication is used to slow down the growth of eflornithine unwanted facial hair in women.
	eflornithivnx2.proboards102.com (685 words)

	topical eflornithine (Vaniqa (R)) in hirsutism - General Practice Notebook
		eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase present in hair follicles
		eflornithine cream was applied twice daily for 24 weeks, followed by an 8-week no treatment period
		in the UK topical eflornithine is being marketed as a treatment to reduce the frequency of a woman's usual method of hair removal and not as a replacement for the current method
	www.gpnotebook.co.uk /simplepage.cfm?ID=x20050629122728305140 (1143 words)

	Topical chemotherapy of experimental CNS-trypanosomiasis: drug combinations
		In the early stage the parasites are confined to the blood, lymph and tissues, and can be easily cured with pentamidine, used exclusively for Trypanosoma brucei gambiense infections, and diminazene aceturate (berenil) or suramin, used in both infections.
		At the present time, eflornithine with melarsoprol is the only clearly effective combination.
		Unfortunately, eflornithine, due to its price and production problems, is not widely available, leaving this and other eflornithine combinations without much future.
	www.fao.org /docrep/W5781E/w5781e0e.htm (1283 words)

	Arch Otolaryngol Head Neck Surg -- Abstract: alpha-difluoromethylornithine ototoxicity. Chemoprevention clinical trial ... (Site not responding. Last check: 2007-11-03)
		were randomized to receive oral eflornithine at daily doses between 0.5 and
		As the daily dose of eflornithine increased, the magnitude and incidence of
		Administration of eflornithine is associated with a predictable shift in
	archotol.ama-assn.org /cgi/content/abstract/123/12/1281 (248 words)

	Eflornithine Cream - Treatment for unwanted hair
		Eflornithine works by inhibiting the growth of facial hair and was shown in controlled clinical trials to provide clinically meaningful and statistically significant improvement in the reduction of facial hair growth in women.
		In most cases, unwanted facial hair is caused by hereditary factors.
		Results demonstrated clinically and statistically significant improvement in the reduction of facial hair growth in women treated with eflornithine compared with the group that was treated with a placebo cream.
	hirsutism.homestead.com /Eflornithine.html (509 words)

	Eflornithine (Topical)
		Eflornithine (ee-FLOOR-nith-een) is used to slow down bodily substances called enzymes that help hair grow.
		Mothers who are taking this medicine and wish to breast-feed should discuss this with their doctor.
		Use of any information is solely at the user's own risk.
	allnutritionals.com /drugs/e/eflornithine-topical.shtml (811 words)

	Clinical Trial: Eflornithine in Treating Patients At High Risk of Developing Prostate Cancer
		The use of eflornithine may be an effective way to prevent the development of prostate cancer.
		PURPOSE: Randomized phase II trial to determine the effectiveness of eflornithine in preventing prostate cancer in patients who are at high risk of developing the disease.
		Compare the levels of polyamines (putrescine, spermidine, and spermine) and progression-related genes in the prostate tissue of patients at high genetic risk for prostate cancer treated with eflornithine (DFMO) vs placebo.
	clinicaltrials.gov /ct/show/NCT00006101 (483 words)

	Eflornithine (Systemic)
		Eflornithine (ee-FLOR-ni-theen) is used to treat African sleeping sickness, a disease caused byprotozoa (tiny one-celled animals).
		Mothers who are receiving this medicine and who wish to breast-feed should discuss this with their doctor.
		Adults-Dose is based on body weight and must be determined by your doctor.
	allnutritionals.com /drugs/e/eflornithine-systemic.shtml (955 words)

	Healthopedia.com Drugs Information - Eflornithine (Ornidyl)
		Eflornithine (ee-FLOR-ni-theen) is used to treat African sleeping sickness, a disease caused by protozoa (tiny one-celled animals).
		USP DI® and Advice for the Patient® are registered trademarks of USP used under license to Micromedex, a business of Thomson Healthcare Inc. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
		Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
	www.healthopedia.com /drugs/detailed/eflornithine-systemic (206 words)

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