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Topic: Elastin

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	Biomechanics - Wikipedia, the free encyclopedia
		The research and analysis can be carried forth on multiple levels, from the molecular, wherein molecular biomaterials such as collagen and elastin are considered, to the macroscopic level, all the way up to the tissue and organ level.
		The passive mechanical response of a particular tissue can be attributed to the various proteins, such as elastin and collagen, living cells, ground substances such as proteoglycans, and the orientations of fibers within the tissue.
		Elastin is also a major load-bearing constituent within skin, the vasculature, and connective tissues.
	en.wikipedia.org /wiki/Biomechanics (0 words)

	Elastin
		In the dermal connective tissue, the elastin fibers are thin and sinuous.
		Elastin is a large fibrous protein which is formed by spiral filaments than can be compared to springs.
		Elastin owes its properties to its thin structure which resembles that of rubber.
	kappaelastin.com /html/elastin.html (0 words)

	Elastin Research - Childrens Hospital Los Angeles
		We are interested in the structure and the role of elastin in the function of the valve cusp.
		The stiffness of aortic valve cusp elastin is roughly 1/2,000 of that of the whole intact valve cusp material.
		Degradation of elastin caused a significant increase in radial dimensions, with a corresponding decrease in radial extensibility and an increase in radial stiffness.
	www.childrenshospitalla.org /11945.cfm (0 words)

	Elastin and Collagen breakthrough Ethocyn
		Elastin is an extremely insoluble protein due to the extensive cross-linking at lysine residues.
		Elastin is found in all vertebrates studied except the primitive cyclosomes but has not been identified in invertebrates.
		Mammalian tropoelastin, the soluble precursor to elastin is a moderately conserved protein with an estimated 5.8 million years resulting in a 1% amino acid difference.
	www.freehealthguide.com /elastin (0 words)

	Elastin gene expression during aortic wall remodeling in response to sustained hypertension
		The purpose of this study is to evaluate the effects of altering wall motion, intralumenal pressure, and tensile stress on elastin.
		Elastin remodeling in response to acute, sustained hypertension was studied using a rat mid-thoracic aortic coarctation model.
		Acute, sustained hypertension induces elastin protein expression and subsequent increase in arterial wall thickness in response to aortic coarctation.
	www.stanford.edu /dept/biology/biohonors/Biologist/Maak01.htm (0 words)

	Two new elastin cross-links having pyridine skeleton. Implication of ammonia in elastin cross-linking in vivo.
		Implication of ammonia in elastin cross-linking in vivo.
		Isolation and structure analysis of two amino acids from bovine ligamentum nuchae elastin hydrolysates revealed the presence of pyridine cross-links in elastin.
		The concentration of IDP was significantly elevated in aorta elastin of rat with chronic liver cirrhosis induced by carbon tetrachloride (mean +/- S.D.; 11.1 +/- 0.9 nmol/mg elastin) when compared with normal rats (5.9 +/- 1.5 nmol/mg elastin).
	www.arclab.org /medlineupdates/abstract_11278561.html (0 words)

	Age-related changes in the glycation of human aortic elastin. (Site not responding. Last check: 2007-10-22)
		Non-enzymatic glycation of proteins is a consequence of hyperglycemia in diabetes and correlates with aging.
		Human insoluble elastins were prepared from macro- and microscopic unaltered regions of thoracic aortas, obtained from 68 accident victims, distributed in 15 age-groups, using the method of Starcher and Galione.
		These results are consistent with the interpretation that because of its long biological half-life, elastin is susceptible to the slow process of glycation and the following modifications would contribute to the age-related changes of connective tissue.
	www.arclab.org /medlineupdates/abstract_15036419.html (0 words)

	Impaired Distal Airway Development in Mice Lacking Elastin -- Wendel et al. 23 (3): 320 -- American Journal of ...
		Elastin is a major component of the mammalian lung, predominantly found in the alveoli.
		of elastin is implicated in the pathogenesis of emphysema (4),
		elastin expression is confined to the mesenchyme surrounding the
	ajrcmb.atsjournals.org /cgi/content/full/23/3/320 (0 words)

	News in Science - Can damaged tissues spring back into shape? - 13/09/2002
		An Australian team is ready to test a synthetic form of elastin — the stretchy component of arteries, lungs, bladders, ligaments and skin — for tissue repair in humans.
		One difference, however, is that the synthetic elastin is bound together using small amounts of a chemical 'cement' called glutaraldehyde, rather than the chemical that occurs in the original.
		Synthetic elastin could then be used to help scientists further understand the properties of natural elastin, as well as for applied research.
	www.abc.net.au /science/news/stories/s675466.htm (0 words)

	Ron Fields Nutrition - Dogs, Elastin
		Elastin is a combination of selective herbs, which help to restore mobility and the freedom of movement.
		Elastin will help protect your dog from wear and tear in its joints and contribute towards minimising the symptoms of deteriorating mobility caused by age.
		Elastin has been developed from the most up-to-date nutritional scientific knowledge specifically to prevent and remedy impaired motive ability.
	www.ronfieldsnutrition.co.uk /dogselastin.htm (0 words)

	Decreased elastin in vessel walls puts the pressure on -- D’Armiento 112 (9): 1308 -- Journal of Clinical ...
		The characterization of mice haploinsufficient for elastin (Eln
		An elastin gene mutation producing abnormal tropoelastin and abnormal elastic fibres in a patient with autosomal dominant cutis laxa.
		The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis.
	www.jci.org /cgi/content/full/112/9/1308 (0 words)

	CHEST: Lung Elastin and Matrix - ) (Site not responding. Last check: 2007-10-22)
		This is accomplished through the selective binding and subsequent release of growth factors and cytokines, and through its interaction with cell surface receptors[2-4] Although collagen and elastic fibers are the major constituents of the extracellular matrix, the overall function is defined by the interrelationships between all the various components.
		Elastin is synthesized and secreted from several cell types in the lung depending on the anatomic location.
		The organization of elastin in the lung extracellular matrix begins at the pseudoglandular stage of lung development in association with sites of airway branching.[25] Elastin synthesis is increased during the canalicular and saccular stage of fetal development and reaches a peak during alveolarization in the neonatal stage.
	www.findarticles.com /p/articles/mi_m0984/is_5_117/ai_62495068 (0 words)

	Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by ...
		Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases.
		Insoluble elastin pretreated with procyanidol oligomers (PCO) was resistant to the hydrolysis induced by both porcine pancreatic and human leukocyte elastases.
		(+) Catechin-insoluble elastin complexes were partially resistant to the degradation induced by human leukocyte elastase but were hydrolysed at the same rate as untreated samples by a constant amount of pancreatic elastase.
	www.cassia.org /library/Biochem%20Pharmacol,%2033%20%2024,%201984%20Dec%2015,%203933-9.htm (0 words)

	Solid-State 13C NMR Reveals Effects of Temperature and Hydration on Elastin -- Perry et al. 82 (2): 1086 -- Biophysical ...
		Elastin is the principal protein component of the elastic fiber in vertebrate tissue.
		Elastin is the principal protein component of the elastic fiber found in vertebrate tissue (Rosenbloom et al., 1993
		Insoluble elastin was purified from bovine nuchal ligament.
	www.biophysj.org /cgi/content/full/82/2/1086 (0 words)

	A critical role for elastin signaling in vascular morphogenesis and disease -- Karnik et al. 130 (2): 411 -- Development
		mutations of one elastin allele cause supravalvular aortic stenosis
		Elastin provides mechanical support to the vessel wall, and signals vascular smooth muscle cells to localize around the elastic lamellae and remain in a quiescent, contractile state.
		Increased Fibulin-5 and Elastin in S100A4/Mts1 Mice With Pulmonary Hypertension
	dev.biologists.org /cgi/content/full/130/2/411 (0 words)

	CHARACTERIZATION OF ELASTIN ASSOCIATED CALCIFICATION (Site not responding. Last check: 2007-10-22)
		Elastin, a hydrophobic protein, is a major connective tissue component of large blood vessels and has a very high propensity for calcification, far exceeding that of the vascular collagenous matrix.
		Elastin auto-fluorescence and brightfield images were analyzed using image analysis software to calculate the ratio of calcium crystal area to elastin fibre area.
		Prerequisite conditions for elastin calcification were 2mM Ca and 2.5mM PO Calcium deposition was predominantly associated with the inner elastic layer (IEL) and the adventitia.
	www.pulsus.com /ccc2003/abs/a603.htm (0 words)

	Newhouse A1
		Both are rings of pure elastin, a sturdy protein made by vertebrate animals that helps skin, lungs and other body parts stretch.
		Replacement blood vessels were, literally, the stars: One video showed a shiny white elastin graft, freshly sewn onto a pig's severed artery, pulsing with blood in a field of red muscle.
		But he thinks elastin might be used sooner in humans to patch holes in the stomach or intestines, perhaps in the next two years.
	www.newhousenews.com /archive/dworkin022704.html (0 words)

	Arterial Elastin (Site not responding. Last check: 2007-10-22)
		Elastin is a rubberlike protein that allows tissues such as arteries to stretch.
		Pure elastin is hard and glassy, and it depends on water from its chemical environment for its rubber-like behavior.
		As an artery ages or as disease sets in, the chemistry of the artery wall changes; we are studying how these changes might affect the elastin.
	www.zoology.ubc.ca /labs/biomaterials/elastin.html (0 words)

	Transcriptional regulation of pulmonary elastin gene expression in elastase-induced injury -- Rich et al. 285 (2): 354 ...
		to the activation of elastin gene transcription (19).
		The cells/tissue that show the high elastin mRNA content are found in the area of the porcine pancreatic elastase injury.
		Transgenic mice carrying the 2.2-kb human elastin gene promoter/CAT reporter transgene were treated with an intratracheal dose of pancreatic elastase (10 µg) or saline solution (control).
	ajplung.physiology.org /cgi/content/full/285/2/L354 (0 words)

	::: EPC ::: Elastin Products Company ::: (Site not responding. Last check: 2007-10-22)
		Due to the recent single case of Mad Cow Disease in Washington State we want to assure you: all of our bovine elastins are prepared from ligaments obtained more than 6 months before the infection occurred.
		Also, in the processing of elastins they are autoclaved and / or / washed with hot NaOH.
		As an Elastin Products Company, Inc. client, now you can enjoy the simple, fast and secure method of ordering your materials and supplies at anytime during the day or night at your own convenience utilizing the Internet.
	www.elastin.com /default2.asp?pagenumber=1 (0 words)

	Chromosomal Mapping of Quantitative Trait Loci Controlling Elastin Content in Rat Aorta -- Gauguier et al. 45 (3): 460 ... (Site not responding. Last check: 2007-10-22)
		A, Distribution of elastin and collagen values (expressed as percent of dry weight), elastin-to-collagen ratios, and correlation between elastin and collagen contents in the aorta of 18-week-old male and female rats, taken together.
		of aortic elastin and the elastin/collagen ratio in the cross.
		Influence of elastin gene polymorphism on the elastin content of the aorta: A study in 2 strains of rat.
	hyper.ahajournals.org /cgi/content/full/45/3/460 (0 words)

	Elastin health and vitamins links
		Elastin health and vitamins links or references to the subject of elastin...
		Pycnogenol ® is a nutrient belonging to the bioflavonoid family whose main functions are antioxidant activity, and the stabilization and maintenance of collagen and elastin, two critical proteins in connective tissue, blood vessels and muscle.
		Grapeseed Extract is a nutrient belonging to the bioflavonoid family whose main functions are antioxidant activity, the stabilization of collagen and the maintenance of elastin, two critical proteins in connective tissue, blood vessels and muscle.
	www.passersbuy.com /healthproducts/elastin.html (0 words)

	Arterial reconstruction using an elastin-based biopolymer (Site not responding. Last check: 2007-10-22)
		Native elastin fragments were dialyzed, solubilized, repolymerized and injection molded into sheets and tubes of compliant, smooth EB, 500µm in thickness.
		Indocyanine green (ICG) dye was painted on the surface of the EB to be bonded to the aortic wall.
		These findings indicate the feasibility of deploying an elastin biomaterial to replace the internal elastic lamina as a means of reconstructing damaged arteries.
	omlc.ogi.edu /pubs/abs/gregory95.html (0 words)

	Building Elastin . Incorporation of Recombinant Human Tropoelastin into Extracellular Matrices using Nonelastogenic ...
		Total mean elastin protein per flask was 0.4, 0.5, 0.8, and 1.6 mg in samples taken on Days 1, 3, 7, and 14, respectively.
		Elastin in a neonatal rat smooth muscle cell culture has greatly decreased susceptibility to proteolysis by human neutrophil elastase.
		Role of plasma and serum proteases in the degradation of elastin.
	ajrcmb.atsjournals.org /cgi/content/full/24/6/733 (0 words)

	=== Wrinkles wrinkles and collagen and elastin ===
		A wrinkle is a ridge or crease of a surface.
		Our wrinkles and collagen and elastin website is extremely new so we have not yet managed to include lots of content, but what we have done so far is researched the very best wrinkles and collagen and elastin sites on the net.
		Our work was endless in order to find the best information we could on wrinkles and collagen and elastin and pick out just a couple of the very best sites for you to visit.
	www.sightings-in1.com /wrinkles/wrinkles-and-collagen-and-elastin.htm (0 words)

	Heparin-binding EGF-like growth factor regulates elastin and FGF-2 expression in pulmonary fibroblasts -- Liu et al. ...
		Elastin is synthesized as a soluble precursor, tropoelastin,
		Elastin mRNA levels were determined by Northern blot analysis.
		Levels of elastin mRNA and transcription in HB-EGF-treated cells are shown as relative to those in control cells.
	ajplung.physiology.org /cgi/content/full/285/5/L1106 (0 words)

	The Nature of Elastin
		A gene for elastin is missing: Dr. Colleen Morris of the University of
		regarding genes, elastin, and the consequences of this discovery for
		What is the difference between the elastin made by individuals with WS and individuals who have inherited supravalvular arterial stenosis
	www.wsf.org /medical/literature/layreader/elastin.htm (0 words)

	Elastin Ampules - pure elastin for healthful skin.
		Elastin Ampules - pure elastin for healthful skin.
		It (10 vial box) is the most potent form of elastin and the very same lyophilized extract that originally made elastin so popular in Europe.
		Reviva Lab's ampules (Collagen, Elastin, Hyaluronic, etc.) are among the world's highest-potency supplements.
	www.healthproductsusa.net /3_elastin_ampules_health.htm (0 words)

	Lung Elastin and Matrix -- Starcher 117 (5 Supplement 1): 229 -- Chest
		Structure of the primary cross-linking amino acids of elastin, desmosine, and isodesmosine.
		tied to elastin metabolism is the 10- to 12-nm glycoprotein microfibrils.
		Hinek, A, Rabinovitch, M (1994) 67-kD elastin binding protein is a protective "companion " of extracellular insoluble elastin and intracellular tropoelastin.
	www.chestjournal.org /cgi/content/full/117/5_suppl_1/229S-a (0 words)

	Ozone, but not nitrogen dioxide, fragments elastin and increases its susceptibility to proteolysis -- Winters et al. ...
		Ozone, but not nitrogen dioxide, fragments elastin and increases its susceptibility to proteolysis -- Winters et al.
		Ozone, but not nitrogen dioxide, fragments elastin and increases its susceptibility to proteolysis
		O3-solubilized elastin ranged in size from 5 to 20 kD.
	ajrccm.atsjournals.org /cgi/content/abstract/150/4/1026 (0 words)

	Action of Tropoelastin and Synthetic Elastin Sequences on Vascular Tone and on Free Ca2+ Level in Human Vascular ...
		Action of Tropoelastin and Synthetic Elastin Sequences on Vascular Tone and on Free Ca2+ Level in Human Vascular Endothelial Cells -- Faury et al.
		To determine the elastin sequence(s) responsible for vasomotor
		for mediating the elastin peptide–related effects is the elastin/laminin
	circres.ahajournals.org /cgi/content/abstract/82/3/328 (0 words)

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