| |
| |
United States Patent Application: 0040091925 |
 | | The solid phase matrix exhibits sufficient hydrophilicity and electropositivity to tightly bind the nucleic acids in a sample. |
 | | Electropositive elements can be rendered sufficiently hydrophilic by hydroxyl (--OH) or other groups, resulting in a solid phase matrix that tightly binds DNA, while proteins or inhibitors do not bind to the solid phase matrix. |
 | | Examples of electropositive materials suitable for purposes of this invention include, but are not limited to, materials generally containing one or more elements selected from the group consisting of aluminum, titanium, zirconium, hafnium, scandium, yttrium, lanthanum, vanadium, tantalum, chromium, molybdenum, tungsten, boron, gallium, indium, germanium, tin, and lead. |
| appft1.uspto.gov /netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-adv.html&r=1&f=G&l=50&d=PG01&S1=589,560&OS=589,560&RS= (13229 words) |
|