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Topic: Elmiron

	Elmiron side effects (Pentosan) and drug interactions - prescription drugs and medications at RxList
		Two patients had severe abdominal pain or diarrhea and dehydration that required hospitalization.
		Because there was not a control group of patients with interstitial cystitis who were concurrently evaluated, it is difficult to determine which events are associated with Elmiron
		The adverse events described below were reported in an unblinded clinical trial of 2499 interstitial cystitis patients treated with Elmiron
	www.rxlist.com /cgi/generic2/pento_ad.htm (373 words)

	Frequently Asked Questions about Elmiron \| Interstitial Cystitis Advice
		Elmiron is typically considered to be a Heparinoid, which means that it is structurally similar to heparin sulfate an element found on the bladder surface mucin.
		Elmiron is thought to work like an artificial GAG layer, and thusly relief may be obtained as the bladder has a chance to be "protected" by this new GAG layer, while the original has time to regenerate and heal.
		Elmiron is quickly becoming the first line of defence when it comes to the treatment of IC with oral medications, despite the fact that it can take several months to see visible results.
	www.icadvice.com /node/9 (1995 words)

	NTP: Abstract for TR-512 - Elmiron (registered)
		Administration of Elmiron® was associated with the presence of vacuolated histiocytes in the mandibular and mesenteric lymph nodes, lung, kidney, and liver of male and female rats.
		Administration of Elmiron® was associated with the presence of vacuolated histiocytes in the mandibular and mesenteric lymph nodes, liver, and spleen of males and females.
		Elmiron® administration caused increased incidences of nonneoplastic lesions (presence of vacuolated histiocytes) of the rectum, lung, mesenteric lymph node, and spleen (males) in rats and of the liver, rectum, mesenteric lymph node, and spleen in mice.
	ntp-server.niehs.nih.gov /index.cfm?objectid=070B4D76-B391-AA90-BD4609F13A5F8915 (1812 words)

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