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Topic: Embryonic


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In the News (Tue 29 Dec 09)

  
  Stem cell - Wikipedia, the free encyclopedia
Embryonic stem cells are cultured cells obtained from the undifferentiated inner mass cells of a blastocyst, an early stage embryo that is 50 to 150 cells.
Embryonic stem cells are stem cells derived from the undifferentiated inner mass cells of a blastocyst, an early stage embryo consisting of 50-150 cells.
Embryonic stem cell researchers are currently attempting to grow the cells beyond the first stages of cell development, to overcome difficulties in host rejection of implanted stem cells, and to control the multiplying of implanted embryonic stem cells, which otherwise multiply uncontrollably, producing a tumor.
en.wikipedia.org /wiki/Stem_cell#Adult_stem_cells   (5715 words)

  
 What are embryonic stem cells? [Stem Cell Information]
Specifically, embryonic stem cells are derived from embryos that develop from eggs that have been fertilized in vitro—in an in vitro fertilization clinic—and then donated for research purposes with informed consent of the donors.
The blastocyst includes three structures: the trophoblast, which is the layer of cells that surrounds the blastocyst; the blastocoel, which is the hollow cavity inside the blastocyst; and the inner cell mass, which is a group of approximately 30 cells at one end of the blastocoel.
Embryonic stem cells that have proliferated in cell culture for six or more months without differentiating, are pluripotent, and appear genetically normal are referred to as an embryonic stem cell line.
stemcells.nih.gov /info/basics/basics3.asp   (1114 words)

  
 Implications of Policy Decisions on Human Embryonic Stem Cell Research in the United States
Although research with human embryonic stem cells was recognized as one of the most promising fields in science by Science, in 1991 (Bloom, 1999), the issue of public funding remains a powerful determinant in the future of stem cell research.
Embryonic germ cells on the other hand are obtained from fetal tissue after miscarriage or abortion and thus carry a lesser ethical burden than the use of embryonic stem cells.
Researchers using human embryonic stem cell lines hope to obtain substantial scientific benefits from a detailed understanding of the process of embryonic stem cell derivation and argue that the methods of derivation may affect the properties of the embryonic stem cells.
hcs.harvard.edu /~epihc/currentissue/spring2001/oestreich.html   (1941 words)

  
 ISSCR :: Stem Cell Science : Frequently Asked Questions
Embryonic stem cells are derived from the cells that make up the inner cell mass of the blastocyst.
Embryonic stem cells, which can form all types of functional adult cells, provide the hope that one day such cells can produce the cells or tissues to grow entire hearts, liver and even kidneys, thus solving the problem of the shortfall of organ donors.
Embryonic stem cell banks have also been established for the potential treatment of a wide variety of genetic and acquired diseases, ranging from neural to blood to pancreatic to heart to skin.
www.isscr.org /science/faq.htm   (6067 words)

  
 Researchers devise way to mass-produce embryonic stem cells
Embryonic stem cells are unspecialized, or undifferentiated, cells that can grow into any of the body's 200 different types of cells.
Also, embryonic stem cells are pluripotent — they can become any kind of cell in the body, while adult stem cells usually develop into a type of cell based on the kind of tissue that they originated from.
The next step is to use human embryonic stem cells, and the researchers have yet to decide which line of stem cells to use.
www.eurekalert.org /pub_releases/2005-03/osu-rdw031505.php   (750 words)

  
 The Anatomy of the Embryonic Disc
The embryonic disc is the mass of cells that sits on the surface of the yolk and gives rise to the chick and its extra-embryonic membranes.
The embryonic disc is also called the blastoderm, the blastodisc, the disc of blastomeres or, at later stages, the blastula.
The first diagram shows the embryonic disc as it sits on the yolk and the plane of section of the slides you will be viewing.
www.uoguelph.ca /zoology/devobio/210labs/embryodisc1.html   (493 words)

  
 Yale researcher testifies in support of embryonic stem cell research
Krause stressed the importance of embryonic stem cell research and the need for the administration to allow federally funded embryonic stem cell studies to proceed.
Krause told the subcommittee that it is not yet known whether adult stem cells have the same ability as embryonic cells to become all cell types.
She also said that in order for scientific discovery to continue rapidly, both adult and embryonic stem cells would need to be studied and compared.
www.eurekalert.org /pub_releases/2001-07/yu-yrt071801.php   (347 words)

  
 The Specious Logic of Embryonic Stem Cell Research
That "promise" is based on the oft-repeated statement that human embryonic stem cells (often described as "master cells" or "blank cells") possess the unique ability to form all cell types in the human body.
It is nothing short of hubris to believe that we can rip embryonic cells out of their normal context in the embryo, inject them into a "host" body, and expect them to perform perfectly every time.
The fact remains that embryonic cells are likely to perform their natural role only in the context of the intact, developing embryo, not as so many harvested crops.
www.nrlc.org /news/2004/NRL08/specious_logic_of_embryonic_stem.htm   (1344 words)

  
 Embryonic Stem Cell Research
What will be discussed here is the procedure of Embryonic stem cell use, as well as other sources of stem cells and the Islamic position on such use, which at this point is not totally clear.
Embryonic stem cells are so greatly looked at because "The stem cell is a unique and essential cell type found in animals.
I personally am unsure as to what the difference is, although some may argue the the use of embryonic stem cells are killing the unused embryo by man by means of taking the cells.
www.angelfire.com /la/IslamicView/StemCell.html   (1657 words)

  
 USATODAY.com - Study: Embryonic stem cells genetically stable   (Site not responding. Last check: 2007-10-09)
WASHINGTON (AP) — Embryonic stem cells develop a relatively small number of mutations and these can be detected by screening, according to a study that researchers say supports the eventual use of stem cells to treat disease.
Peter Stambrook, a cell biologist at the University of Cincinnati and a co-author of the study, said that the most common embryonic stem cell mutation found in the mice was the deletion of a chromosome that is replaced by a second copy of the remaining chromosome.
Embryonic stem cells are the master cells for development.
www.usatoday.com /news/health/genetics/2002-03-12-stem.htm   (676 words)

  
 Embryonic Stem Cell Research: Background, History, Current Policy, and Ethical Concerns
Though embryonic stem cells are not capable of implanting into the uterus and creating an organism, they could be used to understand the factors required for onset of organ formation.
Though human embryonic stem cells were first isolated in 1997, little research with human cells was carried out due to federal restrictions on the use of embryonic tissues for research.
Also, embryonic stem cells that were able to be isolated could only be multiplied 10 to 100 times, meaning quite a few embryos would need to be destroyed in order to obtain enough cells for routine use in clinical settings.
www.goshen.edu /bio/Biol410/BSSpapers99/bensmucker.html   (3207 words)

  
 Support Embryonic Stem Cell Research in N.Y. State | SCRNY.org
Di Scipio, who was injured in a diving accident nearly six years ago, said the religious and right-to-life groups opposed to embryonic stem cell research are causing confusion by not having all the facts.
Temple said embryonic stem cells are the only ones that can be used for spinal cord injuries because adult stem cells are highly specialized and require a genetic alteration beyond their capability.
She said because embryonic stem cells have not decided what they are going to be, they do not require the same genetic alteration.
scrny.org   (1165 words)

  
 Embryonic Stem Cell Debate   (Site not responding. Last check: 2007-10-09)
Embryonic stem cells ARE NOT the same as cord blood stem cells.
Embryonic stem cells come from aborted fetuses and leftover, donated embryos and this is why there is controversy over using federal money for stem cell research..
What we know for sure is that umbilical cord blood stem cells do not present the same ethical or moral issues as embryonic stem cells and most agree that these stem cells are the closest to embryonic stem cells that are safely available for research and treating diseases.
www.cordblooddonor.org /stemcell_debate.htm   (189 words)

  
 Washingtonpost.com: A Crucial Human Cell Isolated, Multiplied
The long-awaited discovery of so-called human embryonic stem cells -- the primordial human cells that give rise to all the specialized tissues in a developing fetus -- was hailed by researchers as a landmark event with vast biomedical potential.
With the therapeutic potential of embryonic cells suddenly very real, advocates are calling for a reexamination of that ban, saying the development of lifesaving applications will be hindered if federal dollars remain off-limits.
Lawyers at the National Institutes of Health were scrambling this week to settle that issue, even as Rep. Jay Dickey (R-Ark.), one of the authors of the congressional ban, reasserted his intention to keep the funding prohibition in place.
www.washingtonpost.com /wp-srv/national/cell110698.htm   (1237 words)

  
 Embryonic Stem Cell Derived Neural Progenitors
Derived from the inner cell mass of the blastocyst, embryonic stem cells can be manipulated to differentiate into neural progenitor cells upon exposure to a specific combination of proteins/growth factors.
Neural progenitor cells that were induced to differentiate from mouse embryonic stem cells expressed certain factors that indicate their potential ability to respond to retinal specific epigenetic cues.
It is possible to apply this understanding to use neural progenitors derived from embryonic stem cells as cell replacement therapy to treat retinal degenerative diseases.
www.unr.nevada.edu /~msargent   (567 words)

  
 Embryonic Development   (Site not responding. Last check: 2007-10-09)
The events of the six-week embryonic stage include differentiation of germ layers into specific body cavities and the formation of the placenta, the umbilical cord, and the embryonic membranes which provide sustenance and protection to the embryo.
The embryonic stage lasts from the beginning of the third week to the end of the eighth week.
Early in the third week, a linear band known as the primitive streak appears along the dorsal midline of the embryonic disc, and establishes a structural foundation for development along a longitudinal axis, and will eventually give rise to the notochord, a primitive beginning of skeletal development.
www.innerbody.com /text/repo52.html   (383 words)

  
 Differentiation of Pluripotent Embryonic Stem Cells Into Cardiomyocytes -- Boheler et al. 91 (3): 189 -- Circulation ...   (Site not responding. Last check: 2007-10-09)
A gene trap approach in mouse embryonic stem cells: the lacZ reporter is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.
In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse.
Embryonic stem cells as an in vitro model for mutagenicity, cytotoxicity and embryotoxicity studies: present state and future prospects.
circres.ahajournals.org /cgi/content/full/91/3/189   (6932 words)

  
 Focus on Social Issues - Frequently Asked Questions: Stem Cell Research   (Site not responding. Last check: 2007-10-09)
While embryonic stem cells receive more press, ongoing research indicates that developed adult stem cells are as flexible as embryonic ones and equally capable of converting into various cell types for healing the body.
So far, success with animal embryonic stem cell experiments is limited and researchers have been unable to move beyond animal studies because of the unpredictability and tumor-causing propensity of these cells.
Today’s destructive embryonic stem-cell research is the latest version of non-consensual human experimentation as tiny humans are dissected like laboratory animals—all in the name of science.
www.family.org /cforum/fosi/bioethics/faqs/a0027980.cfm   (2015 words)

  
 USCCB - Practical Problems with Embryonic Stem Cells   (Site not responding. Last check: 2007-10-09)
“ES [embryonic stem] cells and their derivatives carry the same likelihood of immune rejection as a transplanted organ because, like all cells, they carry the surface proteins, or antigens, by which the immune system recognizes invaders.
For example, because undifferentiated embryonic stem cells can form tumors after transplantation in histocompatible animals, it is important to determine an appropriate state of differentiation before transplantation.
Embryonic stem cells also show genetic instability and carry considerable risks of cancer… When injected under the skin of certain mice, they grow into teratomas, tumors consisting of a jumble of tissue types, from gut to skin to teeth, and the same happens when injected into the brain.”
www.usccb.org /prolife/issues/bioethic/stemcell/obstacles51004.htm   (2126 words)

  
 Embryonic Stem Cell Research
Some Parkinson’s patients who have allowed themselves to be injected with fetal and embryonic tissue, suffered catastrophic consequences when their bodies either had an immune reaction and rejected the foreign material, or else the fetal tissue started dramatically overproducing, resulting in permanent morbidity of the Parkinson’s sufferer.
In spite of intense lobbying and pressure from the pro embryonic research side, the Bush administration rejected their demands that researchers be allowed to use federal funds to destroy embryonic human beings.
More embryonic children are destroyed by birth control than by embryonic stem cell research.
www.christiangallery.com /stemcell.htm   (2284 words)

  
 NEJM -- New Human Embryonic Stem-Cell Lines -- More Is Better
Embryonic stem cells are derived from the inner cell mass of
Embryonic stem cells are derived from the inner cell mass of the blastocyst; cells composing the inner cell mass are isolated and then plated on culture medium, below which is a layer of feeder cells.
of human embryonic stem cells, is therefore an important contribution.
content.nejm.org /cgi/content/full/350/13/1275   (964 words)

  
 Search Results for embryonic - Encyclopædia Britannica
The organization of the embryo as a whole appears to be determined to a large extent during gastrulation, by which process different regions of the blastoderm are displaced and brought into new...
Embryonic stem cells (often referred to as ES cells) are stem cells that are derived from the inner cell mass of a mammalian embryo at a very early stage of development, when it is composed of a...
Darwin and his followers found support for evolution in the study of embryology, the science that investigates the development of organisms from fertilized egg to time of birth or hatching.
www.britannica.com /search?query=embryonic&submit=Find&source=MWTEXT   (490 words)

  
 Embryonic Stem Cell Lines Derived from Human Blastocysts -- Thomson et al. 282 (5391): 1145 -- Science
Embryonic stem (ES) cells are derived from totipotent cells of the early mammalian embryo and are capable of unlimited, undifferentiated
Keller, G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine.
Progenitor and embryonic stem cell transplantation for myocardial angiogenesis and functional restoration.
www.sciencemag.org /cgi/content/full/282/5391/1145   (7027 words)

  
 Poll: Americans Oppose Funding Embryonic Stem Cell Research, Human Cloning
That might make it seem as if Americans are divided on whether they want their tax dollars to pay for research involving the destruction of human embryos or research using adult stem cells.
However, when given a choice between funding all stem cell research (embryonic and adult) or just adult stem cells, Americans said they prefer funding adult stem cell research by a 61 to 23 percent margin.
According to the poll, sponsored by the U.S. Conference of Catholic Bishops, opposition to funding embryonic stem cell research is strongest among women, lower-income groups, senior citizens and those who attend church regularly.
www.lifenews.com /bio434.html   (445 words)

  
 Experts: Bush Stem Cell Policy Limits NIH   (Site not responding. Last check: 2007-10-09)
Although embryonic stem cells have the potential to turn into any cell type in the body, and thus treat various diseases ranging from Parkinson's to diabetes, they are controversial because harvesting them requires the destruction of an embryo.
Lanza charged Bush's policy on embryonic stem cells -- which significantly limited the number of cell lines that could be used for federally funded research to those already in existence -- was driving the NIH decision to fund the adult stem cell projects.
Until embryonic stem cell researchers show their project has a good chance of succeeding, there is no reason for the NIH to fund it, he said.
www.newsmax.com /archives/articles/2003/1/3/63718.shtml   (961 words)

  
 Multilineage Differentiation from Human Embryonic Stem Cell Lines -- Odorico et al. 19 (3): 193 -- Stem Cells
Embryonic stem cells alone are able to support fetal development in the mouse.
Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.
Embryonic stem cells as a model for studying regulation of cellular differentiation.
stemcells.alphamedpress.org /cgi/content/full/19/3/193   (6545 words)

  
 UCSD discovery shows how embryonic stem cells perform 'quality control' inspections
Biologists at the University of California, San Diego have found a fundamental mechanism used by embryonic stem cells to assure that genetically damaged stem cells do not divide and pass along the damage to daughter stem cells.
"What we discovered is a primary mechanism that allows embryonic stem cells to perform quality control inspections during their self-renewal, the process by which these cells undergo unlimited cellular division to produce an unlimited number of daughter cells," says Yang Xu, an associate professor of biology at UCSD who headed the research team.
Xu and his team made their discovery while working with embryonic stem cell lines from mice, which possess the same known properties and capabilities as human embryonic stem cells.
www.eurekalert.org /pub_releases/2004-12/uoc--uds122004.php   (421 words)

  
 genome.gov | Cloning/Embryonic Stem Cells
The experiment that led to the cloning of Dolly the sheep in 1997 was different: It used a cloning technique called somatic cell nuclear transfer and resulted in an animal that was a genetic twin -- although delayed in time -- of an adult sheep.
This technique can also be used to produce an embryo from which cells called embryonic stem (ES) cells could be extracted to use in research into potential therapies for a wide variety of diseases.
Thus, in the past five years, much of the scientific and ethical debate about somatic cell nuclear transfer has focused on its two potential applications: 1) for reproductive purposes, i.e., to produce a child, or 2) for producing a source of ES cells for research.
www.genome.gov /10004765   (1529 words)

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