| | Lippincott-Schwartz Lab (Site not responding. Last check: 2007-09-19) |
 | | The endomembrane system of eukaryotic cells is responsible for delivery of newly synthesized protein and lipid to the outside of the cell; for uptake, processing and degradation of extracellular molecules; and for the regeneration and functioning of intracellular organelles. |
 | | This activity is essential for the maintenance and functioning of the endomembrane system. |
 | | Using a variety of GFP-based fluorescent imaging techniques, including dual-color time-lapse imaging, photobleaching and photoactivation, we have sought to understand the basis for protein targeting and retention within organelles; the processes by which transport intermediates form and move between compartments; and, the principles underlying organelle breakdown, reassembly and maintenance. |
| dir2.nichd.nih.gov /nichd/cbmb/sob/lab_interests.html (500 words) |